Structural basis of human PRPS2 filaments
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 7yk1
Q-score: 0.62
Lu GM, Hu HH, Chang CC, Zhong J, Zhou X, Guo CJ, Zhang T, Li YL, Yin B, Liu JL
Cell Biosci (2023) 13 pp. 100-100 [ Pubmed: 37248548 DOI: doi:10.1186/s13578-023-01037-z ]
- Filament structure of human phosphoribosylpyrophosphate synthetase2. (Complex from Homo sapiens)
- Phosphate ion (94 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Ribose-phosphate pyrophosphokinase 2 (35 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Cryo-EM structure of alpha-synuclein singlet filament from Juvenile-onset synucleinopathy
Resolution: 2.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8bqv
Q-score: 0.74
Yang Y, Garringer HJ, Shi Y, Lovestam S, Peak-Chew S, Zhang X, Kotecha A, Bacioglu M, Koto A, Takao M, Spillantini MG, Ghetti B, Vidal R, Murzin AG, Scheres SHW, Goedert M
Acta Neuropathol (2023) 145 pp. 561-572 [ Pubmed: 36847833 DOI: doi:10.1007/s00401-023-02550-8 ]
- Water (18 Da, Ligand)
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha-synuclein singlet filament extracted from the human brain with jos (Tissue from Homo sapiens)
- Unknown protein (613 Da, Protein from Homo sapiens)
Cryo-EM structure of alpha-synuclein filaments doublet from Juvenile-onset synucleinopathy
Resolution: 2.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 8bqw
Q-score: 0.652
Yang Y, Garringer HJ, Shi Y, Lovestam S, Peak-Chew S, Zhang X, Kotecha A, Bacioglu M, Koto A, Takao M, Spillantini MG, Ghetti B, Vidal R, Murzin AG, Scheres SHW, Goedert M
Acta Neuropathol (2023) 145 pp. 561-572 [ Pubmed: 36847833 DOI: doi:10.1007/s00401-023-02550-8 ]
- Water (18 Da, Ligand)
- Unknown protein (783 Da, Protein from Homo sapiens)
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha-synuclein doublet filament extracted from the human brain with jos (Tissue from Homo sapiens)
E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5P
Resolution: 2.3 Å
EM Method: Single-particle
Fitted PDBs: 7xmu
Q-score: 0.664
Hu HH, Lu GM, Chang CC, Li Y, Zhong J, Guo CJ, Zhou X, Yin B, Zhang T, Liu JL
eLife (2022) 11 [ Pubmed: 35736577 DOI: doi:10.7554/eLife.79552 ]
- Phosphate ion (94 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- E.coli prpp syhthetase filament structure complex with adp,pi, mg2+ and r5p (Cellular component from Escherichia coli str. K-12 substr. MG1655)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 5-o-phosphono-alpha-d-ribofuranose (230 Da, Ligand)
- Ribose-phosphate pyrophosphokinase (35 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7xmv
Q-score: 0.625
Hu HH, Lu GM, Chang CC, Li Y, Zhong J, Guo CJ, Zhou X, Yin B, Zhang T, Liu JL
eLife (2022) 11 [ Pubmed: 35736577 DOI: doi:10.7554/eLife.79552 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Water (18 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 5-o-phosphono-alpha-d-ribofuranose (230 Da, Ligand)
- E.coli prpp syhthetase filament structure complex with adp,amp, mg2+ and r5p (Cellular component from Escherichia coli str. K-12 substr. MG1655)
- Ribose-phosphate pyrophosphokinase (35 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
E.coli phosphoribosylpyrophosphate (PRPP) synthetase type B filament bound with Pi
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7xn3
Q-score: 0.574
Hu HH, Lu GM, Chang CC, Li Y, Zhong J, Guo CJ, Zhou X, Yin B, Zhang T, Liu JL
eLife (2022) 11 [ Pubmed: 35736577 DOI: doi:10.7554/eLife.79552 ]
- Phosphate ion (94 Da, Ligand)
- E.coli prpp syhthetase type b filament structure complex with pi (Cellular component from Escherichia coli str. K-12 substr. MG1655)
- Water (18 Da, Ligand)
- Ribose-phosphate pyrophosphokinase (35 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
Structure of bare actin filament
Resolution: 5.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 6bno
Q-score: 0.211
Gurel PS, Kim LY, Ruijgrok PV, Omabegho T, Bryant Z, Alushin GM
eLife (2017) 6 [ Pubmed: 29199952 DOI: doi:10.7554/eLife.31125 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Actin, alpha skeletal muscle (41 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Bare actin filament (42 kDa, Complex from Oryctolagus cuniculus)