Influenza A virus Hemagglutinin H5/Vietnam/1204/2004 in complex with D04 Fab
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8ume
Q-score: 0.462
Feldman J, Ramos ASF, Vu M, Maurer DP, Rosado VC, Lingwood D, Bajic G, Schmidt AG
Sci Immunol (2025) 10 pp. eado9572-eado9572 [ Pubmed: 39854479 DOI: doi:10.1126/sciimmunol.ado9572 ]
- Fab light chain (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab heavy chain (24 kDa, Protein from Homo sapiens)
- Hemagglutinin (62 kDa, Protein from Influenza A virus)
- Ha/fab (350 MDa, Complex from Homo sapiens)
Resolution: 2.68 Å
EM Method: Single-particle
Fitted PDBs: 9ekf
Q-score: 0.597
Morano NC, Guo Y, Becker JE, Li Z, Yu J, Ho DD, Shapiro L, Kwong PD
Structure (2025) 33 pp. 228-233.e3 [ Pubmed: 39884273 DOI: doi:10.1016/j.str.2025.01.001 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab 65c6 light chain (23 kDa, Protein from Homo sapiens)
- Complex of hemagglutinin from h5n1 ha a/texas/37/2024 with antibody (360 kDa, Complex from Homo sapiens)
- Fab 65c6 heavy chain (25 kDa, Protein from Homo sapiens)
- Hemagglutinin (65 kDa, Protein from Influenza A virus)
Hemagglutinin H1 New Caledonia 1999 in complex with monoclonal antibody Fab 43_S0008
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 9b2m
Q-score: 0.377
Ataca S, Sangesland M, de Paiva Froes Rocha R, Torrents de la Pena A, Ronsard L, Boyoglu-Barnum S, Gillespie RA, Tsybovsky Y, Stephens T, Moin SM, Lederhofer J, Creanga A, Andrews SF, Barnes RM, Rohrer D, Lonberg N, Graham BS, Ward AB, Lingwood D, Kanekiyo M
Cell Rep (2024) 43 pp. 114990-114990 [ DOI: doi:10.1016/j.celrep.2024.114990 Pubmed: 39580804 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain monoclonal antibody fab 3_s0008 (24 kDa, Protein from Mus sp.)
- Hemagglutinin ha1 chain (37 kDa, Protein from Influenza A virus)
- Heavy chain monoclonal antibody fab 3_s0008 (24 kDa, Protein from Mus sp.)
- Hemagglutinin h1 new caledonia 1999 in complex with monoclonal antibody fab 43_s0008 (330 kDa, Complex from Homo sapiens)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus)
Cryo-EM structure of hemagglutinin H5 A/Texas/37/2024 in complex with LSTa and antibody CR9114
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 9dwe
Q-score: 0.559
Good MR, Fernandez-Quintero ML, Ji W, Rodriguez AJ, Han J, Ward AB, Guthmiller JJ
Nat Commun (2024) 15 pp. 10768-10768 [ DOI: doi:10.1038/s41467-024-54934-3 Pubmed: 39737954 ]
- Hemagglutinin (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin h5 a/texas/37/2024 homotrimer bound to lsta and cr9114 fab (Complex from Homo sapiens)
- Cr9114 fab fab heavy chain (12 kDa, Protein from Homo sapiens)
- Hemagglutinin (65 kDa, Protein from Influenza A virus)
- Cr9114 fab (Complex from Homo sapiens)
- Cr9114 fab light chain (11 kDa, Protein from Homo sapiens)
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 9dzq
Q-score: 0.335
Miller RJ, Durie IA, Gingerich AD, Elbehairy MA, Branch AG, Davis RG, Abbadi N, Brindley MA, Mousa JJ
Nat Commun (2024) 15 pp. 10825-10825 [ DOI: doi:10.1038/s41467-024-55101-4 Pubmed: 39738006 ]
- Human antibody piv3hn-05 light chain (22 kDa, Protein from Homo sapiens)
- Human antibody piv3hn-13 heavy chain (23 kDa, Protein from Homo sapiens)
- Complex of the piv3 hn protein with two human antibodies (200 kDa, Complex from Human respirovirus 3)
- Hemagglutinin-neuraminidase (51 kDa, Protein from Human respirovirus 3)
- Human antibody piv3hn-13 light chain (23 kDa, Protein from Homo sapiens)
- Human antibody piv3hn-05 heavy chain (24 kDa, Protein from Homo sapiens)
Vaccine elicited Fab C968.180 with influenza H10 JD13 HA trimer
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 9bu6
Q-score: 0.489
Mantus GE, Chopde AJ, Gorman J, Cominsky LY, Ourahmane A, Creanga A, Shimberg GD, Gillespie RA, Van Wazer DJ, Zhou T, Gajjala SR, Williams C, Maestle E, Reed DS, Serebryannyy L, Costner P, Holman L, Casazza JP, Koup RA, Dropulic LK, Kwong PD, McDermott AB, Kanekiyo M, Andrews SF
Sci Transl Med (2025) 17 pp. eadr8373-eadr8373 [ DOI: doi:10.1126/scitranslmed.adr8373 Pubmed: 39742506 ]
- Fab c968.180 heavy chain (14 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin ha2 (26 kDa, Protein from Influenza A virus)
- Fab c968.180 light chain (11 kDa, Protein from Homo sapiens)
- Hemagglutinin ha1 (35 kDa, Protein from Influenza A virus)
- Vaccine elicited fab c968.180 with influenza h10 jd13 ha trimer (Complex from Influenza A virus)
Vaccine elicited Fab c115.131 with influenza H10 JD13 HA trimer
Resolution: 3.96 Å
EM Method: Single-particle
Fitted PDBs: 9bu8
Q-score: 0.414
Mantus GE, Chopde AJ, Gorman J, Cominsky LY, Ourahmane A, Creanga A, Shimberg GD, Gillespie RA, Van Wazer DJ, Zhou T, Gajjala SR, Williams C, Maestle E, Reed DS, Serebryannyy L, Costner P, Holman L, Casazza JP, Koup RA, Dropulic LK, Kwong PD, McDermott AB, Kanekiyo M, Andrews SF
Sci Transl Med (2025) 17 pp. eadr8373-eadr8373 [ DOI: doi:10.1126/scitranslmed.adr8373 Pubmed: 39742506 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin ha2 (26 kDa, Protein from Influenza A virus)
- Fab c115.131 light chain (11 kDa, Protein from Homo sapiens)
- Hemagglutinin ha1 (35 kDa, Protein from Influenza A virus)
- Vaccine elicited fab c115.131 with influenza h10 jd13 ha trimer (Complex from Influenza A virus)
- Fab c115.131 heavy chain (13 kDa, Protein from Homo sapiens)
Influenza A virus Hemagglutinin H3/Darwin/6/2021 in complex with Fab ADI-85666
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 9bdf
Q-score: 0.563
Maurer D, Ferreira Ramos AS, Bajic G, Aaron GS
To Be Published
- Adi-85666 fab light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Adi-85666 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Ha/fab (350 MDa, Complex from Homo sapiens)
- Hemagglutinin (57 kDa, Protein from Influenza A virus)
Influenza A virus Hemagglutinin H3/Darwin/6/2021 in complex with Fab ADI-85647
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 9bdg
Q-score: 0.551
Maurer D, Ferreira Ramos AS, Bajic G, Aaron GS
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Influenza a virus hemagglutinin h3/darwin/6/2021 in complex with fab adi-85647 (350 kDa, Complex from Homo sapiens)
- Fab adi-85647 heavy chain (25 kDa, Protein from Homo sapiens)
- Ig-like domain-containing protein (23 kDa, Protein from Homo sapiens)
- Hemagglutinin (57 kDa, Protein from Influenza A virus)
A3R-Gi complex bound to adenosine
Resolution: 3.27 Å
EM Method: Single-particle
Fitted PDBs: 8yh2
Q-score: 0.379
Oshima HS, Ogawa A, Sano FK, Akasaka H, Kawakami T, Iwama A, Okamoto HH, Nagiri C, Wei FY, Shihoya W, Nureki O
Nat Commun (2024) 15 pp. 9294-9294 [ Pubmed: 39511145 DOI: doi:10.1038/s41467-024-53473-1 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Rattus rattus)
- Scfv16 (27 kDa, Protein from Mus musculus)
- A3r-gi complex bound to adenosine (Complex from Ovis aries)
- Adenosine (267 Da, Ligand)
- Hemagglutinin,adenosine receptor a3,gfp chimera (88 kDa, Protein from Human orthopneumovirus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2,guanine nucleotide-binding protein g(i) subunit alpha-1 chimera (48 kDa, Protein from Homo sapiens)