Hemagglutinin H1 New Caledonia 1999 in complex with monoclonal antibody Fab 43_S0008
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 9b2m
Q-score: 0.377
Ataca S, Sangesland M, de Paiva Froes Rocha R, Torrents de la Pena A, Ronsard L, Boyoglu-Barnum S, Gillespie RA, Tsybovsky Y, Stephens T, Moin SM, Lederhofer J, Creanga A, Andrews SF, Barnes RM, Rohrer D, Lonberg N, Graham BS, Ward AB, Lingwood D, Kanekiyo M
Cell Rep (2024) 43 pp. 114990-114990 [ DOI: doi:10.1016/j.celrep.2024.114990 Pubmed: 39580804 ]
- Heavy chain monoclonal antibody fab 3_s0008 (24 kDa, Protein from Mus sp.)
- Light chain monoclonal antibody fab 3_s0008 (24 kDa, Protein from Mus sp.)
- Hemagglutinin h1 new caledonia 1999 in complex with monoclonal antibody fab 43_s0008 (330 kDa, Complex from Homo sapiens)
- Hemagglutinin ha1 chain (37 kDa, Protein from Influenza A virus)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8ur5
Q-score: 0.429
Ellis D, Dosey A, Boyoglu-Barnum S, Park YJ, Gillespie R, Syeda H, Hutchinson GB, Tsybovsky Y, Murphy M, Pettie D, Matheson N, Chan S, Ueda G, Fallas JA, Carter L, Graham BS, Veesler D, Kanekiyo M, King NP
Cell Rep (2023) 42 pp. 113552-113552 [ Pubmed: 38096058 DOI: doi:10.1016/j.celrep.2023.113552 ]
- I53_dn5 nanoparticle displaying the trimeric ha heads with heptad domain, th-1heptad-i53_dn5 (local refinement of th-1heptad) (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Trimer head ha,hemagglutinin ha1 chain (44 kDa, Protein from synthetic construct)
- Trimer head ha (Complex from synthetic construct)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8ur7
Q-score: 0.403
Ellis D, Dosey A, Boyoglu-Barnum S, Park YJ, Gillespie R, Syeda H, Hutchinson GB, Tsybovsky Y, Murphy M, Pettie D, Matheson N, Chan S, Ueda G, Fallas JA, Carter L, Graham BS, Veesler D, Kanekiyo M, King NP
Cell Rep (2023) 42 pp. 113552-113552 [ Pubmed: 38096058 DOI: doi:10.1016/j.celrep.2023.113552 ]
- Pentamer (Complex from synthetic construct)
- I53_dn5 nanoparticle displaying the trimeric ha heads with heptad domain, th-6heptad-i53_dn5 (Complex)
- Trimer head ha (Complex from synthetic construct)
- Trimer head ha,hemagglutinin ha1 chain (48 kDa, Protein from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Boyoglu-Barnum S, Ellis D, Gillespie RA, Hutchinson GB, Park YJ, Moin SM, Acton OJ, Ravichandran R, Murphy M, Pettie D, Matheson N, Carter L, Creanga A, Watson MJ, Kephart S, Ataca S, Vaile JR, Ueda G, Crank MC, Stewart L, Lee KK, Guttman M, Baker D, Mascola JR, Veesler D, Graham BS, King NP, Kanekiyo M
Nature (2021) 592 pp. 623-628 [ DOI: doi:10.1038/s41586-021-03365-x Pubmed: 33762730 ]
Boyoglu-Barnum S, Ellis D, Gillespie RA, Hutchinson GB, Park YJ, Moin SM, Acton OJ, Ravichandran R, Murphy M, Pettie D, Matheson N, Carter L, Creanga A, Watson MJ, Kephart S, Ataca S, Vaile JR, Ueda G, Crank MC, Stewart L, Lee KK, Guttman M, Baker D, Mascola JR, Veesler D, Graham BS, King NP, Kanekiyo M
Nature (2021) 592 pp. 623-628 [ DOI: doi:10.1038/s41586-021-03365-x Pubmed: 33762730 ]
Boyoglu-Barnum S, Ellis D, Gillespie RA, Hutchinson GB, Park YJ, Moin SM, Acton OJ, Ravichandran R, Murphy M, Pettie D, Matheson N, Carter L, Creanga A, Watson MJ, Kephart S, Ataca S, Vaile JR, Ueda G, Crank MC, Stewart L, Lee KK, Guttman M, Baker D, Mascola JR, Veesler D, Graham BS, King NP, Kanekiyo M
Nature (2021) 592 pp. 623-628 [ DOI: doi:10.1038/s41586-021-03365-x Pubmed: 33762730 ]
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7kna
Q-score: 0.499
Boyoglu-Barnum S, Ellis D, Gillespie RA, Hutchinson GB, Park YJ, Moin SM, Acton OJ, Ravichandran R, Murphy M, Pettie D, Matheson N, Carter L, Creanga A, Watson MJ, Kephart S, Ataca S, Vaile JR, Ueda G, Crank MC, Stewart L, Lee KK, Guttman M, Baker D, Mascola JR, Veesler D, Graham BS, King NP, Kanekiyo M
Nature (2021) 592 pp. 623-628 [ DOI: doi:10.1038/s41586-021-03365-x Pubmed: 33762730 ]
CryoEM structure of influenza hemagglutinin A/Victoria/361/2011 in complex with cyno antibody 3B10
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 6wzt
Q-score: 0.315
Darricarrere N, Qiu Y, Kanekiyo M, Creanga A, Gillespie RA, Moin SM, Saleh J, Sancho J, Chou TH, Zhou Y, Zhang R, Dai S, Moody A, Saunders KO, Crank MC, Mascola JR, Graham BS, Wei CJ, Nabel GJ
Sci Transl Med (2021) 13 [ DOI: doi:10.1126/scitranslmed.abe5449 Pubmed: 33658355 ]
- Cyno antibody light chain (23 kDa, Protein from Macaca fascicularis)
- Cyno antibody (Complex)
- Hemagglutinin (Complex from Macaca fascicularis)
- Hemagglutinin (56 kDa, Protein from Influenza A virus)
- Cyno antibody heavy chain (24 kDa, Protein from Macaca fascicularis)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Influenza hemagglutinin a/victoria/361/2011 in complex with 3b10 fab (336 kDa, Complex from Influenza A virus)
Darricarrere N, Qiu Y, Kanekiyo M, Creanga A, Gillespie RA, Moin SM, Saleh J, Sancho J, Chou TH, Zhou Y, Zhang R, Dai S, Moody A, Saunders KO, Crank MC, Mascola JR, Graham BS, Wei CJ, Nabel GJ
Sci Transl Med (2021) 13 [ DOI: doi:10.1126/scitranslmed.abe5449 Pubmed: 33658355 ]
- Cyno antibody heavy chain (Protein from Macaca fascicularis)
- Hemagglutinin (Complex from Influenza A virus)
- Influenza hemagglutinin a/vietnam/1203/2004 in complex with 1c4 fab (336 kDa, Complex)
- 1c4 fab (Complex from Macaca fascicularis)
- Influenza hemagglutinin (a/vietnam/1203/2004) (Protein from Influenza A virus)
- Cyno antibody light chain (Protein from Macaca fascicularis)
CryoEM structure of influenza hemagglutinin A/Michigan/45/2015 in complex with cyno antibody 1C4
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6xgc
Q-score: 0.392
Darricarrere N, Qiu Y, Kanekiyo M, Creanga A, Gillespie RA, Moin SM, Saleh J, Sancho J, Chou TH, Zhou Y, Zhang R, Dai S, Moody A, Saunders KO, Crank MC, Mascola JR, Graham BS, Wei CJ, Nabel GJ
Sci Transl Med (2021) 13 [ DOI: doi:10.1126/scitranslmed.abe5449 Pubmed: 33658355 ]
- 1c4 fab heavy chain (25 kDa, Protein from Macaca fascicularis)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/Michigan/45/2015(H1N1)))
- Hemagglutinin ha1 chain (36 kDa, Protein from Influenza A virus (A/Michigan/45/2015(H1N1)))
- 1c4 fab light chain (22 kDa, Protein from Macaca fascicularis)
- 1c4 fab (Complex from Macaca fascicularis)
- Hemagglutinin (Complex from Influenza A virus (A/Michigan/45/2015(H1N1)))
- A/michigan/45/2015(h1n1) hemagglutinin in complex with 1c4 fab (320 MDa, Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)