Resolution: 3.96 Å
EM Method: Single-particle
Fitted PDBs: 8d21
Q-score: 0.395
Andrews SF, Cominsky LY, Shimberg GD, Gillespie RA, Gorman J, Raab JE, Brand J, Creanga A, Gajjala SR, Narpala S, Cheung CSF, Harris DR, Zhou T, Gordon I, Holman L, Mendoza F, Houser KV, Chen GL, Mascola JR, Graham BS, Kwong PD, Widge A, Dropulic LK, Ledgerwood JE, Kanekiyo M, McDermott AB
Sci Transl Med (2023) 15 pp. eade4976-eade4976 [ DOI: doi:10.1126/scitranslmed.ade4976 Pubmed: 37075126 ]
- 1b06 light chain (11 kDa, Protein from Homo sapiens)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus)
- 1b06 heavy chain (13 kDa, Protein from Homo sapiens)
- Cryo-em structure of the vrc321 clinical trial, vaccine-elicited, human antibody 1b06 in complex with a stabilized nc99 ha trimer (Complex)
- Hemagglutinin ha1 chain (36 kDa, Protein from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 1b06 fab with nc99 ha trimer (Complex from Influenza A virus)
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 7l0l
Q-score: 0.555
Andrews SF, Raab JE, Gorman J, Gillespie RA, Cheung CSF, Rawi R, Cominsky LY, Boyington JC, Creanga A, Shen CH, Harris DR, Olia AS, Nazzari AF, Zhou T, Houser KV, Chen GL, Mascola JR, Graham BS, Kanekiyo M, Ledgerwood JE, Kwong PD, McDermott AB
Nat Med (2022) 28 pp. 373-382 [ Pubmed: 35115707 DOI: doi:10.1038/s41591-021-01636-8 ]
- Hemagglutinin ha1 chain (38 kDa, Protein from Influenza A virus (A/Canada/720/2005(H2N2)))
- 316-310-1b11 heavy chain (25 kDa, Protein from Homo sapiens)
- 316-310-1b11 fab in complex with an h2 can05 ha trimer (Complex from Influenza A virus)
- 316-310-1b11 light chain (23 kDa, Protein from Homo sapiens)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/Canada/720/2005(H2N2)))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.87 Å
EM Method: Single-particle
Fitted PDBs: 7mfg
Q-score: 0.411
Andrews SF, Raab JE, Gorman J, Gillespie RA, Cheung CSF, Rawi R, Cominsky LY, Boyington JC, Creanga A, Shen CH, Harris DR, Olia AS, Nazzari AF, Zhou T, Houser KV, Chen GL, Mascola JR, Graham BS, Kanekiyo M, Ledgerwood JE, Kwong PD, McDermott AB
Nat Med (2022) 28 pp. 373-382 [ Pubmed: 35115707 DOI: doi:10.1038/s41591-021-01636-8 ]
- 310-030-1d06 light (11 kDa, Protein from Homo sapiens)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus)
- 310-030-1d06 heavy (13 kDa, Protein from Homo sapiens)
- Hemagglutinin ha1 chain (36 kDa, Protein from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 310-030-1d06 fab in complex with an h1 nc99 ha trimer (Complex from Influenza A virus)
Cryo-EM structure of SRR2899884.46167H+MEDI8852L fab in complex with Victoria HA
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 7kc1
Q-score: 0.461
Chuang GY, Shen CH, Cheung CS, Gorman J, Creanga A, Joyce MG, Leung K, Rawi R, Wang L, Yang ES, Yang Y, Zhang B, Zhang Y, Kanekiyo M, Zhou T, DeKosky BJ, Graham BS, Mascola JR, Kwong PD
Front Immunol (2021) 12 pp. 662909-662909 [ DOI: doi:10.3389/fimmu.2021.662909 Pubmed: 34135892 ]
- Fab heavy chain (24 kDa, Protein from Homo sapiens)
- Fab light chain (22 kDa, Protein from Homo sapiens)
- Hemagglutinin (38 kDa, Protein from Influenza A virus)
- Fusion protein of hemagglutinin and envelope glycoprotein (25 kDa, Protein from Human immunodeficiency virus 1)
- Cryo-em structure of srr2899884.46167h+medi8852l fab in complex with victoria ha (Complex from Influenza A virus)
- Cryo-em structure of srr2899884.46167h+medi8852l fab in complex with victoria ha (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)