CryoEM structure of A/Solomon Islands/3/2006 H1 HA in complex with 05.GC.w2.3C10-H1_SI06
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8u44
Q-score: 0.387
McIntire KM, Meng H, Lin TH, Kim W, Moore NE, Han J, McMahon M, Wang M, Malladi SK, Mohammed BM, Zhou JQ, Schmitz AJ, Hoehn KB, Carreno JM, Yellin T, Suessen T, Middleton WD, Teefey SA, Presti RM, Krammer F, Turner JS, Ward AB, Wilson IA, Kleinstein SH, Ellebedy AH
J Exp Med (2024) 221 [ DOI: doi:10.1084/jem.20240668 Pubmed: 38935072 ]
- Hemagglutinin ha2 chain (26 kDa, Protein from Influenza A virus)
- Immune complex of a/solomon islands/3/2006 h1 ha with fab 3c10 (Complex from Homo sapiens)
- Hemagglutinin ha1 chain (40 kDa, Protein from Influenza A virus)
- 05.gc.w2.3c10-h1_si06 heavy chain (25 kDa, Protein from Homo sapiens)
- 05.gc.w2.3c10-h1_si06 light chain (25 kDa, Protein from Homo sapiens)
- Fab (Complex from Homo sapiens)
- Ha (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8tqi
Q-score: 0.499
Suryadevara N, Otrelo-Cardoso AR, Kose N, Hu YX, Binshtein E, Wolters RM, Greninger AL, Handal LS, Carnahan RH, Moscona A, Jardetzky TS, Crowe Jr JE
Nat Microbiol (2024) 9 pp. 2128-2143 [ Pubmed: 38858594 DOI: doi:10.1038/s41564-024-01722-w ]
- Light chain fab rpiv3-23 (23 kDa, Protein from Homo sapiens)
- Hemagglutinin-neuraminidase glycoprotein (Complex from Human respirovirus 3)
- Recombinant rpiv3-28 fab (Complex from Homo sapiens)
- Heavy chain fab rpiv3-28 (23 kDa, Protein from Homo sapiens)
- Light chain fab rpiv3-28 (23 kDa, Protein from Homo sapiens)
- Heavy chain fab rpiv3-23 (24 kDa, Protein from Homo sapiens)
- Hemagglutinin-neuraminidase (50 kDa, Protein from Human respirovirus 3)
- Hpiv3 hn in complex with rpiv3-23 and rpiv3-28 fabs (Complex from Human respirovirus 3)
- Recombinant rpiv3-23 fab (Complex from Homo sapiens)
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 8v7o
Q-score: 0.453
Nagashima KA, Dzimianski JV, Yang M, Abendroth J, Sautto GA, Ross TM, DuBois RM, Edwards TE, Mousa JJ
Structure (2024) 32 pp. 1079- [ Pubmed: 38810648 DOI: doi:10.1016/j.str.2024.05.001 ]
- #58 light chain (11 kDa, Protein from Homo sapiens)
- Complex of cobra ha x6 with #58 fab (Complex from Homo sapiens)
- Hemagglutinin (62 kDa, Protein from Influenza A virus)
- #58 heavy chain (14 kDa, Protein from Homo sapiens)
Cryo-EM structure of X6 COBRA (H1N1) hemagglutinin bound to CR6261 Fab
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8f38
Q-score: 0.615
Nagashima KA, Dzimianski JV, Yang M, Abendroth J, Sautto GA, Ross TM, DuBois RM, Edwards TE, Mousa JJ
Structure (2024) 32 pp. 1079- [ Pubmed: 38810648 DOI: doi:10.1016/j.str.2024.05.001 ]
- Water (18 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cr6261 fab light chain (23 kDa, Protein from Homo sapiens)
- Hemagglutinin (63 kDa, Protein from synthetic construct)
- Cryo-em structure of x6 cobra (h1n1) hemagglutinin bound to cr6261 fab (450 kDa, Complex)
- Cr6261 fab heavy chain (24 kDa, Protein from Homo sapiens)
S1V2-72 Fab bound to EHA2 from influenza B/Malaysia/2506/2004
Resolution: 4.98 Å
EM Method: Single-particle
Fitted PDBs: 8udg
Q-score: 0.202
Finney J, Moseman AP, Kong S, Watanabe A, Song S, Walsh Jr RM, Kuraoka M, Kotaki R, Moseman EA, McCarthy KR, Liao D, Liang X, Nie X, Lavidor O, Abbott R, Harrison SC, Kelsoe G
PNAS (2024) 121 pp. e2316964120-e2316964120 [ DOI: doi:10.1073/pnas.2316964120 Pubmed: 38147556 ]
- S1v2-72 light chain (22 kDa, Protein from Homo sapiens)
- S1v2-72 heavy chain (24 kDa, Protein from Homo sapiens)
- Hemagglutinin (17 kDa, Protein from Influenza B virus (B/Malaysia/2506/2004))
- Complex of two s1v2-72 fabs with postfusion ha2 (Complex from Influenza B virus (B/Malaysia/2506/2004))
1F8 mAb in complex with the computationally optimized broadly reactive H1 influenza hemagglutinin P1
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8ct6
Q-score: 0.485
Dzimianski JV, Han J, Sautto GA, O'Rourke SM, Cruz JM, Pierce SR, Ecker JW, Carlock MA, Nagashima KA, Mousa JJ, Ross TM, Ward AB, DuBois RM
Commun Biol (2023) 6 pp. 454-454 [ Pubmed: 37185989 DOI: doi:10.1038/s42003-023-04793-3 ]
- Cobra p1 hemagglutinin (Complex from Influenza A virus)
- 1f8 heavy chain (23 kDa, Protein from Mus musculus)
- 1f8 monoclonal antibody (Complex from Mus musculus)
- Cobra p1 ha in complex with 1f8 mab (Complex from Homo sapiens)
- Cobra p1 ha (63 kDa, Protein from Influenza A virus)
- 1f8 light chain (23 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of H1 NC99 influenza hemagglutinin bound to Fab 310-63E6
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 7scn
Q-score: 0.534
Sangesland M, Torrents de la Pena A, Boyoglu-Barnum S, Ronsard L, Mohamed FAN, Moreno TB, Barnes RM, Rohrer D, Lonberg N, Ghebremichael M, Kanekiyo M, Ward A, Lingwood D
Immunity (2022) 55 pp. 1693-1709.e8 [ Pubmed: 35952670 DOI: doi:10.1016/j.immuni.2022.07.006 ]
- Hemagglutinin ha2 chain (26 kDa, Protein from Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1))
- 310-63e6 fab, light chain (11 kDa, Protein from Homo sapiens)
- 310-63e6 fab, heavy chain (13 kDa, Protein from Homo sapiens)
- Hemagglutinin ha1 chain (35 kDa, Protein from Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Structure of h1 nc99 influenza hemagglutinin bound to 310-63e6 fab (Complex from Influenza A virus)
Structure of H1 influenza hemagglutinin bound to Fab 310-39G10
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 7sco
Q-score: 0.451
Sangesland M, Torrents de la Pena A, Boyoglu-Barnum S, Ronsard L, Mohamed FAN, Moreno TB, Barnes RM, Rohrer D, Lonberg N, Ghebremichael M, Kanekiyo M, Ward A, Lingwood D
Immunity (2022) 55 pp. 1693-1709.e8 [ Pubmed: 35952670 DOI: doi:10.1016/j.immuni.2022.07.006 ]
- 310-39g10 fab, light chain (11 kDa, Protein from Homo sapiens)
- Hemagglutinin ha2 chain (26 kDa, Protein from Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1))
- 310-39g10 fab, heavy chain (12 kDa, Protein from Homo sapiens)
- Structure of h1 nc99 influenza hemagglutinin bound to fab 310-39g10 (Complex from Influenza A virus)
- Hemagglutinin ha1 chain (35 kDa, Protein from Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)