Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7qxb
Q-score: 0.278
Sekne Z, Ghanim GE, van Roon AM, Nguyen THD
Science (2022) 375 pp. 1173-1176 [ Pubmed: 35201900 DOI: doi:10.1126/science.abn6840 ]
- Telomeric dna (Complex from Homo sapiens)
- Telomerase reverse transcriptase (127 kDa, Protein from Homo sapiens)
- Histone h2b (18 kDa, Protein from Homo sapiens)
- Histones (Complex from Homo sapiens)
- Complex of telomeric dna-bound human telomerase with tpp1-pot1 (Complex)
- Tpp1-pot1 (Complex from Homo sapiens)
- Adrenocortical dysplasia homolog (mouse), isoform cra_a (49 kDa, Protein from Homo sapiens)
- Telomerase reverse transcriptase and telomeric rna (Complex from Homo sapiens)
- Protection of telomeres protein 1 (71 kDa, Protein from Homo sapiens)
- Histone h2a (14 kDa, Protein from Homo sapiens)
- Human telomerase rna (145 kDa, RNA from Homo sapiens)
- Telomeric dna (9 kDa, DNA from Homo sapiens)
cryo-EM Structure of Nucleosome containing mouse histone variant H2A.Z
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7m1x
Q-score: 0.391
Lewis TS, Sokolova V, Jung H, Ng H, Tan D
Nucleic Acids Res (2021) 49 pp. 11379-11391 [ Pubmed: 34643712 DOI: doi:10.1093/nar/gkab907 ]
- Histone h3 (Complex from Xenopus laevis)
- Histone h4 (Complex from Xenopus laevis)
- Dna (136-mer) (45 kDa, DNA from unidentified)
- Dna (136-mer) (45 kDa, DNA from unidentified)
- Nucleosome core particle containing variant h2a.z and canonical core histones (Complex)
- Histone variant h2a.z (Complex from Mus musculus)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Histone h2a.z (13 kDa, Protein from Mus musculus)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Dna (136-mer) (Complex from unidentified)
- Histone h2b (Complex from Xenopus laevis)
- Histone h3 (15 kDa, Protein from Xenopus laevis)
OCT4-SOX2-bound nucleosome - SHL-6
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 6t90
Q-score: 0.451
Michael AK, Grand RS, Isbel L, Cavadini S, Kozicka Z, Kempf G, Bunker RD, Schenk AD, Graff-Meyer A, Pathare GR, Weiss J, Matsumoto S, Burger L, Schubeler D, Thoma NH
Science (2020) 368 pp. 1460-1465 [ Pubmed: 32327602 DOI: doi:10.1126/science.abb0074 ]
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Dna (146-mer) (46 kDa, DNA from synthetic construct)
- Pentanedial (100 Da, Ligand)
- Histone h2b type 1-j (14 kDa, Protein from Homo sapiens)
- Histones (Complex from Homo sapiens)
- Green fluorescent protein,pou domain, class 5, transcription factor 1 (70 kDa, Protein from Homo sapiens)
- G protein/gfp fusion protein,pou domain, class 5, transcription factor 1 (oct4) (Complex from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Transcription factor sox-2 (12 kDa, Protein from Homo sapiens)
- Dna (Complex from synthetic construct)
- Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
- Sox2 (Complex from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Dna (146-mer) (45 kDa, DNA from synthetic construct)
- Ternary complex of oct4-sox2 and shl-6 nucleosome (Complex)
Structure of human Sox11 transcription factor in complex with a nucleosome
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6t7a
Q-score: 0.37
Dodonova SO, Zhu F, Dienemann C, Taipale J, Cramer P
Nature (2020) 580 pp. 669-672 [ DOI: doi:10.1038/s41586-020-2195-y Pubmed: 32350470 ]
- Transcription factor sox-11 (12 kDa, Protein from Homo sapiens)
- Structure of human sox11 transcription factor in complex with a nucleosome (218 kDa, Complex)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Dna (147-mer) (45 kDa, DNA from synthetic construct)
- Dna (147-mer) (45 kDa, DNA from synthetic construct)
- Histone h2a type 1-b/e (16 kDa, Protein from Homo sapiens)
- Histone h2b type 1-k (13 kDa, Protein from Homo sapiens)
- Dna (Complex from synthetic construct)
- Sox11 transcription factor, histones (Complex from Homo sapiens)
- Histone h3.2 (15 kDa, Protein from Homo sapiens)