Cryo-EM structure of human Apo CNGA1 channel in K+/Ca2+
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7lft
Q-score: 0.638
Xue J, Han Y, Zeng W, Wang Y, Jiang Y
Neuron (2021) 109 pp. 1302-1313.e4 [ DOI: doi:10.1016/j.neuron.2021.02.007 Pubmed: 33651975 ]
- Cgmp-gated cation channel alpha-1 (64 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Apo cnga1 homotetramer in k+/ca2+ (Cell from Homo sapiens)
- Water (18 Da, Ligand)
Cryo-EM structure of human cGMP-bound open CNGA1 channel in K+/Ca2+
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7lfw
Q-score: 0.551
Xue J, Han Y, Zeng W, Wang Y, Jiang Y
Neuron (2021) 109 pp. 1302-1313.e4 [ DOI: doi:10.1016/j.neuron.2021.02.007 Pubmed: 33651975 ]
- Cgmp-bound open cnga1 homotetramer in k+/ca2+ (Cell from Homo sapiens)
- Cyclic guanosine monophosphate (345 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Cgmp-gated cation channel alpha-1 (64 kDa, Protein from Homo sapiens)
Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+/Ca2+
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7lfx
Q-score: 0.458
Xue J, Han Y, Zeng W, Wang Y, Jiang Y
Neuron (2021) 109 pp. 1302-1313.e4 [ DOI: doi:10.1016/j.neuron.2021.02.007 Pubmed: 33651975 ]
- Cgmp-bound open cnga1 homotetramer in na+/ca2+ (Cell from Homo sapiens)
- Cyclic guanosine monophosphate (345 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Cgmp-gated cation channel alpha-1 (64 kDa, Protein from Homo sapiens)
Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7lfy
Q-score: 0.416
Xue J, Han Y, Zeng W, Wang Y, Jiang Y
Neuron (2021) 109 pp. 1302-1313.e4 [ DOI: doi:10.1016/j.neuron.2021.02.007 Pubmed: 33651975 ]
- Cgmp-gated cation channel alpha-1 (64 kDa, Protein from Homo sapiens)
- Sodium ion (22 Da, Ligand)
- Cgmp-bound open cnga1 homotetramer in na+ (Cell from Homo sapiens)
- Cyclic guanosine monophosphate (345 Da, Ligand)
- Water (18 Da, Ligand)
Cryo-EM structure of human cGMP-bound CNGA1_E365Q channel in Na+/Ca2+
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7lg1
Q-score: 0.527
Xue J, Han Y, Zeng W, Wang Y, Jiang Y
Neuron (2021) 109 pp. 1302-1313.e4 [ DOI: doi:10.1016/j.neuron.2021.02.007 Pubmed: 33651975 ]
- Calcium ion (40 Da, Ligand)
- Cyclic guanosine monophosphate (345 Da, Ligand)
- Cgmp-bound cnga1_e365q homotetramer in na+/ca2+ (Cell from Homo sapiens)
- Cgmp-gated cation channel alpha-1 (64 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
cryo-EM structure of TRPM4 in apo state with short coiled coil at 3.1 angstrom resolution
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 6bcj
Q-score: 0.502
Guo J, She J, Zeng W, Chen Q, Bai XC, Jiang Y
Nature (2017) 552 pp. 205-209 [ Pubmed: 29211714 DOI: doi:10.1038/nature24997 ]
- Homotetramer of mouse trpm4 (Complex from Mus musculus)
- Sodium ion (22 Da, Ligand)
- Water (18 Da, Ligand)
- Transient receptor potential cation channel subfamily m member 4 (140 kDa, Protein from Mus musculus)
cryo-EM structure of TRPM4 in apo state with long coiled coil at 3.5 angstrom resolution
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 6bcl
Q-score: 0.43
Guo J, She J, Zeng W, Chen Q, Bai XC, Jiang Y
Nature (2017) 552 pp. 205-209 [ Pubmed: 29211714 DOI: doi:10.1038/nature24997 ]
- Homotetramer of mouse trpm4 (Complex from Mus musculus)
- Sodium ion (22 Da, Ligand)
- Transient receptor potential cation channel subfamily m member 4 (140 kDa, Protein from Mus musculus)
cryo-EM structure of TRPM4 in ATP bound state with short coiled coil at 2.9 angstrom resolution
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 6bco
Q-score: 0.509
Guo J, She J, Zeng W, Chen Q, Bai XC, Jiang Y
Nature (2017) 552 pp. 205-209 [ Pubmed: 29211714 DOI: doi:10.1038/nature24997 ]
- Transient receptor potential cation channel subfamily m member 4 (140 kDa, Protein from Mus musculus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Homotetramer mouse trpm4 (Complex from Mus musculus)
cryo-EM structure of TRPM4 in ATP bound state with long coiled coil at 3.3 angstrom resolution
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 6bcq
Q-score: 0.433
Guo J, She J, Zeng W, Chen Q, Bai XC, Jiang Y
Nature (2017) 552 pp. 205-209 [ Pubmed: 29211714 DOI: doi:10.1038/nature24997 ]
- Homotetramer of mouse trpm4 (Complex from Mus musculus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Transient receptor potential cation channel subfamily m member 4 (140 kDa, Protein from Mus musculus)
Resolution: 3.64 Å
EM Method: Single-particle
Fitted PDBs: 5wpq
Q-score: 0.432
Chen Q, She J, Zeng W, Guo J, Xu H, Bai XC, Jiang Y
Nature (2017) 550 pp. 415-418 [ DOI: doi:10.1038/nature24035 Pubmed: 29019981 ]
- Mucolipin-1 (66 kDa, Protein from Mus musculus)
- Homotetramer of mouse trpml1 (66 kDa, Cellular component from Mus musculus)
- Sodium ion (22 Da, Ligand)