Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8rcr
Q-score: 0.329
Ekundayo B, Arullampalam P, Gerber CE, Hammerli AF, Guichard S, Boukenna M, Ross-Kaschitza D, Lochner M, Rougier JS, Stahlberg H, Abriel H, Ni D
Nat Commun (2025) 16 pp. 833-833 [ DOI: doi:10.1038/s41467-025-56131-2 Pubmed: 39828793 ]
- Cholesterol (386 Da, Ligand)
- Homotetramer (500 MDa, Complex from Homo sapiens)
- Transient receptor potential cation channel subfamily m member 4 (83 kDa, Protein from Homo sapiens)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8rcu
Q-score: 0.325
Ekundayo B, Arullampalam P, Gerber CE, Hammerli AF, Guichard S, Boukenna M, Ross-Kaschitza D, Lochner M, Rougier JS, Stahlberg H, Abriel H, Ni D
Nat Commun (2025) 16 pp. 833-833 [ DOI: doi:10.1038/s41467-025-56131-2 Pubmed: 39828793 ]
- 4-chloranyl-2-[2-(3-iodanylphenoxy)ethanoylamino]benzoic acid (431 Da, Ligand)
- Homotetramer (500 MDa, Complex from Homo sapiens)
- Transient receptor potential cation channel subfamily m member 4 (83 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
Cryo-EM structure of tetrameric human SAMHD1 State V - Depleted relaxed
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 8qxo
Q-score: 0.417
Acton OJ, Sheppard D, Kunzelmann S, Caswell SJ, Nans A, Burgess AJO, Kelly G, Morris ER, Rosenthal PB, Taylor IA
Nat Commun (2024) 15 pp. 3775-3775 [ DOI: doi:10.1038/s41467-024-48237-w Pubmed: 38710701 ]
- Magnesium ion (24 Da, Ligand)
- Homotetramer of samhd1 (Complex from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Deoxynucleoside triphosphate triphosphohydrolase samhd1 (72 kDa, Protein from Homo sapiens)
- 2'-deoxyadenosine 5'-triphosphate (491 Da, Ligand)
- 2'-deoxycytidine-5'-triphosphate (467 Da, Ligand)
- Fe (iii) ion (55 Da, Ligand)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8fhw
Q-score: 0.579
Washington EJ, Zhou Y, Hsu AL, Petrovich M, Tenor JL, Toffaletti DL, Guan Z, Perfect JR, Borgnia MJ, Bartesaghi A, Brennan RG
bioRxiv (2024) [ Pubmed: 36993618 DOI: doi:10.1101/2023.03.14.530545 ]
- Uridine-5'-diphosphate (404 Da, Ligand)
- 6-o-phosphono-alpha-d-glucopyranose (260 Da, Ligand)
- Alpha,alpha-trehalose-phosphate synthase (udp-forming) (76 kDa, Protein from Cryptococcus neoformans var. grubii H99)
- Cryo-em structure of cryptococcus neoformans trehalose-6-phosphate synthase homotetramer in complex with uridine diphosphate and glucose-6-phosphate (307 kDa, Complex from Cryptococcus neoformans var. grubii H99)
Type IIS Restriction Endonuclease PaqCI, DNA bound
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 8epx
Q-score: 0.545
Kennedy MA, Hosford CJ, Azumaya CM, Luyten YA, Chen M, Morgan RD, Stoddard BL
Nucleic Acids Res (2023) 51 pp. 4467-4487 [ DOI: doi:10.1093/nar/gkad228 Pubmed: 36987874 ]
- Homotetramer paqci with associated dna duplexes (Complex from Paucibacter aquatile)
- Dna 1b (6 kDa, DNA from DNA molecule)
- Dna 4a (4 kDa, DNA from DNA molecule)
- Dna 1a (7 kDa, DNA from DNA molecule)
- Calcium ion (40 Da, Ligand)
- Dna 2b (5 kDa, DNA from DNA molecule)
- Dna 3a (5 kDa, DNA from DNA molecule)
- Dna 3b (5 kDa, DNA from DNA molecule)
- Type iis restriction endonuclease paqci (56 kDa, Protein from Paucibacter aquatile)
- Dna 2a (4 kDa, DNA from DNA molecule)
- Dna 4b (4 kDa, DNA from DNA molecule)
Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+/Ca2+
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7lfx
Q-score: 0.458
Xue J, Han Y, Zeng W, Wang Y, Jiang Y
Neuron (2021) 109 pp. 1302-1313.e4 [ DOI: doi:10.1016/j.neuron.2021.02.007 Pubmed: 33651975 ]
- Cyclic guanosine monophosphate (345 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Cgmp-gated cation channel alpha-1 (64 kDa, Protein from Homo sapiens)
- Cgmp-bound open cnga1 homotetramer in na+/ca2+ (Cell from Homo sapiens)
Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7lfy
Q-score: 0.416
Xue J, Han Y, Zeng W, Wang Y, Jiang Y
Neuron (2021) 109 pp. 1302-1313.e4 [ DOI: doi:10.1016/j.neuron.2021.02.007 Pubmed: 33651975 ]
- Water (18 Da, Ligand)
- Cgmp-bound open cnga1 homotetramer in na+ (Cell from Homo sapiens)
- Cgmp-gated cation channel alpha-1 (64 kDa, Protein from Homo sapiens)
- Sodium ion (22 Da, Ligand)
- Cyclic guanosine monophosphate (345 Da, Ligand)
CBD-bound full-length rat TRPV2 in nanodiscs, state 2
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6u88
Q-score: 0.527
Pumroy RA, Samanta A, Liu Y, Hughes TE, Zhao S, Yudin Y, Rohacs T, Han S, Moiseenkova-Bell VY
eLife (2019) 8 [ Pubmed: 31566564 DOI: doi:10.7554/eLife.48792 ]
- Homotetramer of rat trpv2 (Complex from Rattus norvegicus)
- Transient receptor potential cation channel subfamily v member 2 (86 kDa, Protein from Rattus norvegicus)
- Cannabidiol (314 Da, Ligand)
CBD-bound full-length rat TRPV2 in nanodiscs, state 1
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6u8a
Q-score: 0.497
Pumroy RA, Samanta A, Liu Y, Hughes TE, Zhao S, Yudin Y, Rohacs T, Han S, Moiseenkova-Bell VY
eLife (2019) 8 [ Pubmed: 31566564 DOI: doi:10.7554/eLife.48792 ]
- Homotetramer of rat trpv2 (Complex from Rattus norvegicus)
- Transient receptor potential cation channel subfamily v member 2 (86 kDa, Protein from Rattus norvegicus)
- Cannabidiol (314 Da, Ligand)
cryo-EM structure of TRPM4 in apo state with short coiled coil at 3.1 angstrom resolution
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 6bcj
Q-score: 0.502
Guo J, She J, Zeng W, Chen Q, Bai XC, Jiang Y
Nature (2017) 552 pp. 205-209 [ Pubmed: 29211714 DOI: doi:10.1038/nature24997 ]
- Sodium ion (22 Da, Ligand)
- Homotetramer of mouse trpm4 (Complex from Mus musculus)
- Water (18 Da, Ligand)
- Transient receptor potential cation channel subfamily m member 4 (140 kDa, Protein from Mus musculus)