Structure of human soluble guanylate cyclase in the inactive state at 3.1 angstrom
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8hbe
Q-score: 0.526
Nitric Oxide (2023) 134-135 pp. 17-22 [ DOI: doi:10.1016/j.niox.2023.03.002 Pubmed: 36972843 ]
- Guanylate cyclase soluble subunit alpha-1 (77 kDa, Protein from Homo sapiens)
- Human soluble guanylate cyclase (Complex from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Guanylate cyclase soluble subunit beta-1 (70 kDa, Protein from Homo sapiens)
Consensus map of human soluble guanylate cyclase in the inactive state at 3.2 angstrom
Nitric Oxide (2023) 134-135 pp. 17-22 [ DOI: doi:10.1016/j.niox.2023.03.002 Pubmed: 36972843 ]
Focus refined map of N-lobe of soluble guanylate cyclase in the inactive state at 3.1 angstrom
Nitric Oxide (2023) 134-135 pp. 17-22 [ DOI: doi:10.1016/j.niox.2023.03.002 Pubmed: 36972843 ]
Focus refined map of C-lobe of human soluble guanylate cyclase in the inactive state at 3.1 angstrom
Nitric Oxide (2023) 134-135 pp. 17-22 [ DOI: doi:10.1016/j.niox.2023.03.002 Pubmed: 36972843 ]
Structure of human soluble guanylate cyclase in the NO+Rio state at 3.1 angstrom
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8hbf
Q-score: 0.539
Nitric Oxide (2023) 134-135 pp. 17-22 [ DOI: doi:10.1016/j.niox.2023.03.002 Pubmed: 36972843 ]
- Guanylate cyclase soluble subunit beta-1 (70 kDa, Protein from Homo sapiens)
- Guanylate cyclase soluble subunit alpha-1 (77 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Human soluble guanylate cyclase (Complex from Homo sapiens)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Nitric oxide (30 Da, Ligand)
- Methyl ~{n}-[4,6-bis(azanyl)-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]-~{n}-methyl-carbamate (422 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
Nitric Oxide (2023) 134-135 pp. 17-22 [ DOI: doi:10.1016/j.niox.2023.03.002 Pubmed: 36972843 ]
Focus refined map of N-lobe of human soluble guanylate cyclase in the NO+Rio state at 3.1 angstrom
Nitric Oxide (2023) 134-135 pp. 17-22 [ DOI: doi:10.1016/j.niox.2023.03.002 Pubmed: 36972843 ]
Focus refined map of C-lobe of human soluble guanylate cyclase in the NO+Rio state at 3.1 angstrom
Nitric Oxide (2023) 134-135 pp. 17-22 [ DOI: doi:10.1016/j.niox.2023.03.002 Pubmed: 36972843 ]
Structure of human soluble guanylate cyclase in the NO-activated state at 3.1 angstrom
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8hbh
Q-score: 0.537
Nitric Oxide (2023) 134-135 pp. 17-22 [ DOI: doi:10.1016/j.niox.2023.03.002 Pubmed: 36972843 ]
- Guanylate cyclase soluble subunit beta-1 (70 kDa, Protein from Homo sapiens)
- Guanylate cyclase soluble subunit alpha-1 (77 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Human soluble guanylate cyclase (Complex from Homo sapiens)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Nitric oxide (30 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
Consensus map of huamn soluble guanylate cyclase in the NO-activated state at 3.2 angstrom
Nitric Oxide (2023) 134-135 pp. 17-22 [ DOI: doi:10.1016/j.niox.2023.03.002 Pubmed: 36972843 ]