Cryo-EM structure of the GPR61-Gs complex
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 8kgk
Q-score: 0.469
Nie Y, Qiu Z, Chen S, Chen Z, Song X, Ma Y, Huang N, Cyster JG, Zheng S
Nat Commun (2023) 14 pp. 5901-5901 [ DOI: doi:10.1038/s41467-023-41654-3 Pubmed: 37737235 ]
- Gpr61 and mini-gs (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Nanobody 35 (17 kDa, Protein from Lama glama)
- Nb35 (Complex from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cryo-em structure of the gpr61 and mini-gs complex with nb35 (Complex)
- Guanine nucleotide-binding protein g(olf) subunit alpha,guanine nucleotide-binding protein g(s) subunit alpha isoforms short (29 kDa, Protein from Homo sapiens)
- G-protein coupled receptor 61 (42 kDa, Protein from Homo sapiens)
Cryo-EM structure of the GPR161-Gs complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8kh4
Q-score: 0.48
Nie Y, Qiu Z, Chen S, Chen Z, Song X, Ma Y, Huang N, Cyster JG, Zheng S
Nat Commun (2023) 14 pp. 5901-5901 [ DOI: doi:10.1038/s41467-023-41654-3 Pubmed: 37737235 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Nanobody 35 (17 kDa, Protein from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Cryo-em structure of the gpr161 and mini-gs complex with nb35 (Complex from Homo sapiens)
- G-protein coupled receptor 161 (41 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(olf) subunit alpha,guanine nucleotide-binding protein g(s) subunit alpha isoforms short (29 kDa, Protein from Homo sapiens)
Cryo-EM structure of the adhesion GPCR ADGRF1 in complex with miniGs
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7wu3
Q-score: 0.501
Qu X, Qiu N, Wang M, Zhang B, Du J, Zhong Z, Xu W, Chu X, Ma L, Yi C, Han S, Shui W, Zhao Q, Wu B
Nature (2022) 604 pp. 779-785 [ DOI: doi:10.1038/s41586-022-04580-w Pubmed: 35418679 ]
- Nanobody nb35 (17 kDa, Protein from Lama glama)
- Nanobody nb35 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Adhesion g-protein coupled receptor f1 (74 kDa, Protein from Homo sapiens)
- [(2~{r})-2-oxidanyl-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propyl] hexadecanoate (496 Da, Ligand)
- The adhesion gpcr adgrf1 in complex with minigs (Complex from Homo sapiens)