Human cardiac myosin II and associated essential light chain in the rigor conformation
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8efd
Q-score: 0.318
Doran MH, Rynkiewicz MJ, Rassici D, Bodt SML, Barry ME, Bullitt E, Yengo CM, Moore JR, Lehman W
J Gen Physiol (2023) 155 [ DOI: doi:10.1085/jgp.202213267 Pubmed: 36633586 ]
- Myosin light chain 1/3, skeletal muscle isoform (20 kDa, Protein from Mus musculus)
- Beta-cardiac myosin ii (99 kDa, Protein from Homo sapiens)
- Mouse skeletal essential light chain (Complex from Mus musculus)
- Complex of the human beta cardiac myosin ii in the rigor form with the associated essential light chain. (Complex)
- Human beta-cardiac myosin ii (Complex from Homo sapiens)
Human beta-cardiac myosin II bound to ADP-MG2+ and the associated essential light chain
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8efe
Q-score: 0.323
Doran MH, Rynkiewicz MJ, Rassici D, Bodt SML, Barry ME, Bullitt E, Yengo CM, Moore JR, Lehman W
J Gen Physiol (2023) 155 [ DOI: doi:10.1085/jgp.202213267 Pubmed: 36633586 ]
- Magnesium ion (24 Da, Ligand)
- Myosin light chain 1/3, skeletal muscle isoform (20 kDa, Protein from Mus musculus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Beta-cardiac myosin ii (99 kDa, Protein from Homo sapiens)
- Mouse skeletal essential light chain (Complex from Mus musculus)
- Complex of the human beta cardiac myosin ii bound to adp-mg2+ with the associated essential light chain. (Complex)
- Human beta-cardiac myosin ii (Complex from Homo sapiens)
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 8efh
Q-score: 0.458
Doran MH, Rynkiewicz MJ, Rassici D, Bodt SML, Barry ME, Bullitt E, Yengo CM, Moore JR, Lehman W
J Gen Physiol (2023) 155 [ DOI: doi:10.1085/jgp.202213267 Pubmed: 36633586 ]
- Magnesium ion (24 Da, Ligand)
- Human cardiac tropomyosin (Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Beta-cardiac myosin ii (99 kDa, Protein from Homo sapiens)
- Tropomyosin alpha-1 chain (32 kDa, Protein from Homo sapiens)
- Actin, alpha cardiac muscle 1 (42 kDa, Protein from Sus scrofa)
- Cardiac f-actin complex (Complex from Sus scrofa)
- Human cardiac actin-tropomyosin-beta-myosin ii complex bound to adpmg2+. (Complex)
- Human beta-cardiac myosin ii (Complex from Homo sapiens)
Helical reconstruction of the human cardiac actin-tropomyosin-myosin complex in the rigor form
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 8efi
Q-score: 0.435
Doran MH, Rynkiewicz MJ, Pavadai E, Bodt SML, Rasicci D, Moore JR, Yengo CM, Bullitt E, Lehman W
J Gen Physiol (2023) 155 [ DOI: doi:10.1085/jgp.202213274 Pubmed: 36459134 ]
- Magnesium ion (24 Da, Ligand)
- Human cardiac tropomyosin (Complex from Homo sapiens)
- Myosin-7 (223 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Human cardiac myosin ii (Complex from Homo sapiens)
- Tropomyosin alpha-1 chain (32 kDa, Protein from Homo sapiens)
- Actin, alpha cardiac muscle 1 (42 kDa, Protein from Sus scrofa)
- Cardiac f-actin complex (Complex from Sus scrofa)
- Human cardiac actin-tropomyosin-beta-myosin ii complex in the rigor form. (Complex)
Helical reconstruction of the human cardiac actin-tropomyosin-myosin loop 4 7G mutant complex
Resolution: 3.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8enc
Q-score: 0.405
Doran MH, Rynkiewicz MJ, Pavadai E, Bodt SML, Rasicci D, Moore JR, Yengo CM, Bullitt E, Lehman W
J Gen Physiol (2023) 155 [ DOI: doi:10.1085/jgp.202213274 Pubmed: 36459134 ]
- Human beta-cardiac myosin ii with seven (366-372) loop 4 residues mutated to glycine. (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Human cardiac tropomyosin (Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Tropomyosin alpha-1 chain (32 kDa, Protein from Homo sapiens)
- Myosin-7 (222 kDa, Protein from Homo sapiens)
- Cardiac f-actin complex (Complex from Sus scrofa)
- Actin, alpha cardiac muscle 1 (42 kDa, Protein from Sus scrofa)
- Human cardiac actin-tropomyosin-beta-myosin ii complex with 7g loop 4 mutation (Complex)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6xe9
Q-score: 0.266
Yang S, Tiwari P, Lee KH, Sato O, Ikebe M, Padron R, Craig R
Nature (2020) 588 pp. 521-525 [ Pubmed: 33268893 DOI: doi:10.1038/s41586-020-3007-0 ]
- Smooth muscle myosin ii (530 kDa, Complex from Meleagris gallopavo)
- Myosin ii heavy chain (smooth muscle) (229 kDa, Protein from Meleagris gallopavo)
- Myosin light chain 9 (19 kDa, Protein from Meleagris gallopavo)
- Myosin light chain smooth muscle isoform (16 kDa, Protein from Meleagris gallopavo)
The Central Role of the Tail in Switching Off Myosin II in Cells
Yang S, Lee KH, Woodhead JL, Sato O, Ikebe M, Craig R
J Gen Physiol (2019) 151 pp. 1081-1093 [ DOI: doi:10.1085/jgp.201912431 Pubmed: 31387899 ]
The Structure of the Actin-Smooth Muscle Myosin Motor Domain Complex in the Rigor State
Resolution: 6.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 6bih
Q-score: 0.133
Banerjee C, Hu Z, Huang Z, Warrington JA, Taylor DW, Trybus KM, Lowey S, Taylor KA
J Struct Biol (2017) 200 pp. 325-333 [ Pubmed: 29038012 DOI: doi:10.1016/j.jsb.2017.10.003 ]
- Alpha-actin (Complex from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Filamentous muscle alpha-actin decorated with the motor domain of recombinant smooth muscle myosin ii motor domain expressed in sf9 cells (Complex)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Actin, alpha skeletal muscle (42 kDa, Protein from Oryctolagus cuniculus)
- Myosin-11 (91 kDa, Protein from Gallus gallus)
- Myosin ii (Complex from Gallus gallus)
The Structure of the Relaxed Thick Filaments from Lethocerus Flight Muscle
Hu Z, Taylor DW, Reedy MK, Perz-Edwards RJ, Taylor KA
Sci Adv (2016) 2 [ Pubmed: 27704041 DOI: doi:10.1126/sciadv.1600058 ]
- Myosin ii (520 kDa, Protein from Lethocerus indicus)
- Myofilin (30 kDa, Protein from Lethocerus indicus)
- Flightin (19 kDa, Protein from Lethocerus indicus)
- Paramyosin (100 kDa, Protein from Lethocerus indicus)
- Thick filament from lethocerus (waterbug) flight muscle (Sample)
Resolution: 23.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 3jax
Q-score: 0.048
Sulbaran G, Alamo L, Pinto A, Marquez G, Mendez F, Padron R, Craig R
PNAS (2015) 112 pp. e5660-e5668 [ Pubmed: 26443857 DOI: doi:10.1073/pnas.1513439112 ]