Cryo-EM reconstruction of TC-NER transcription elongation complex with STK19 (map IV)
Mevissen TET, Kummecke M, Schmid EW, Farnung L, Walter JC
Cell (2024) 187 pp. 7091-7106.e24 [ DOI: doi:10.1016/j.cell.2024.10.020 Pubmed: 39547228 ]
- Rna polymerase ii proteins (Complex from Sus scrofa)
- Nucleic acid (Complex from synthetic construct)
- Dda1, elof1, stk19 (Complex from Homo sapiens)
- Csa, ddb1 (Complex from Homo sapiens)
- Transcription-coupled nucleotide excision repair complex (Complex)
- Csb, uvssa (Complex from Homo sapiens)
Cryo-EM reconstruction of TC-NER transcription elongation complex with STK19 (map III)
Mevissen TET, Kummecke M, Schmid EW, Farnung L, Walter JC
Cell (2024) 187 pp. 7091-7106.e24 [ DOI: doi:10.1016/j.cell.2024.10.020 Pubmed: 39547228 ]
- Rna polymerase ii proteins (Complex from Sus scrofa)
- Nucleic acid (Complex from synthetic construct)
- Dda1, elof1, stk19 (Complex from Homo sapiens)
- Csa, ddb1 (Complex from Homo sapiens)
- Transcription-coupled nucleotide excision repair complex (Complex)
- Csb, uvssa (Complex from Homo sapiens)
Cryo-EM reconstruction of TC-NER transcription elongation complex with STK19 (map II)
Mevissen TET, Kummecke M, Schmid EW, Farnung L, Walter JC
Cell (2024) 187 pp. 7091-7106.e24 [ DOI: doi:10.1016/j.cell.2024.10.020 Pubmed: 39547228 ]
- Rna polymerase ii proteins (Complex from Sus scrofa)
- Nucleic acid (Complex from synthetic construct)
- Dda1, elof1, stk19 (Complex from Homo sapiens)
- Csa, ddb1 (Complex from Homo sapiens)
- Transcription-coupled nucleotide excision repair complex (Complex)
- Csb, uvssa (Complex from Homo sapiens)
Cryo-EM reconstruction of TC-NER transcription elongation complex with STK19 (map V)
Mevissen TET, Kummecke M, Schmid EW, Farnung L, Walter JC
Cell (2024) 187 pp. 7091-7106.e24 [ DOI: doi:10.1016/j.cell.2024.10.020 Pubmed: 39547228 ]
- Rna polymerase ii proteins (Complex from Sus scrofa)
- Nucleic acid (Complex from synthetic construct)
- Dda1, elof1, stk19 (Complex from Homo sapiens)
- Csa, ddb1 (Complex from Homo sapiens)
- Transcription-coupled nucleotide excision repair complex (Complex)
- Csb, uvssa (Complex from Homo sapiens)
Cryo-EM reconstruction of TC-NER transcription elongation complex with STK19 (map VI)
Mevissen TET, Kummecke M, Schmid EW, Farnung L, Walter JC
Cell (2024) 187 pp. 7091-7106.e24 [ DOI: doi:10.1016/j.cell.2024.10.020 Pubmed: 39547228 ]
- Rna polymerase ii proteins (Complex from Sus scrofa)
- Nucleic acid (Complex from synthetic construct)
- Dda1, elof1, stk19 (Complex from Homo sapiens)
- Csa, ddb1 (Complex from Homo sapiens)
- Transcription-coupled nucleotide excision repair complex (Complex)
- Csb, uvssa (Complex from Homo sapiens)
Cryo-EM reconstruction of TC-NER transcription elongation complex with STK19 (map VII)
Mevissen TET, Kummecke M, Schmid EW, Farnung L, Walter JC
Cell (2024) 187 pp. 7091-7106.e24 [ DOI: doi:10.1016/j.cell.2024.10.020 Pubmed: 39547228 ]
- Transcription-coupled nucleotide excision repair complex (Complex)
- Rna polymerase ii proteins (Complex from Sus scrofa)
- Nucleic acid (Complex from synthetic construct)
- Csa, ddb1 (Complex from Homo sapiens)
- Dda1, elof1, stk19 (Complex from Homo sapiens)
- Csb, uvssa (Complex from Homo sapiens)
Cryo-EM reconstruction of TC-NER transcription elongation complex with STK19 (map VIII)
Mevissen TET, Kummecke M, Schmid EW, Farnung L, Walter JC
Cell (2024) 187 pp. 7091-7106.e24 [ DOI: doi:10.1016/j.cell.2024.10.020 Pubmed: 39547228 ]
- Rna polymerase ii proteins (Complex from Sus scrofa)
- Nucleic acid (Complex from synthetic construct)
- Dda1, elof1, stk19 (Complex from Homo sapiens)
- Csa, ddb1 (Complex from Homo sapiens)
- Transcription-coupled nucleotide excision repair complex (Complex)
- Csb, uvssa (Complex from Homo sapiens)
Cryo-EM reconstruction of TC-NER transcription elongation complex with STK19 (Consensus refinement)
Mevissen TET, Kummecke M, Schmid EW, Farnung L, Walter JC
Cell (2024) 187 pp. 7091-7106.e24 [ DOI: doi:10.1016/j.cell.2024.10.020 Pubmed: 39547228 ]
- Rna polymerase ii proteins (Complex from Sus scrofa)
- Nucleic acid (Complex from synthetic construct)
- Dda1, elof1, stk19 (Complex from Homo sapiens)
- Csa, ddb1 (Complex from Homo sapiens)
- Transcription-coupled nucleotide excision repair complex (Complex)
- Csb, uvssa (Complex from Homo sapiens)
E. coli RNA polymerase paused at ops site
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8pdy
Q-score: 0.409
Zuber PK, Said N, Hilal T, Wang B, Loll B, Gonzalez-Higueras J, Ramirez-Sarmiento CA, Belogurov GA, Artsimovitch I, Wahl MC, Knauer SH
Nat Commun (2024) 15 pp. 3040-3040 [ Pubmed: 38589445 DOI: doi:10.1038/s41467-024-47368-4 ]
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase subunit omega (10 kDa, Protein from Escherichia coli)
- Transcription complex (Complex from Escherichia coli)
- Dna and rna (Complex from Escherichia coli)
- Dna-directed rna polymerase subunit alpha (36 kDa, Protein from Escherichia coli)
- Dna-directed rna polymerase subunit beta (150 kDa, Protein from Escherichia coli)
- Transcription elongation complex paused at ops site, assembled on fully complementary nucleic acid scaffold (399 kDa, Complex)
- Rna (5'-r(p*up*gp*gp*cp*gp*gp*up*ap*gp*cp*gp*u)-3') (5 kDa, RNA from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase subunit beta' (156 kDa, Protein from Escherichia coli)
- Non-template dna (35-mer) (12 kDa, DNA from Escherichia coli)
- Template dna (35-mer) (12 kDa, DNA from Escherichia coli)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8pfg
Q-score: 0.471
Zuber PK, Said N, Hilal T, Wang B, Loll B, Gonzalez-Higueras J, Ramirez-Sarmiento CA, Belogurov GA, Artsimovitch I, Wahl MC, Knauer SH
Nat Commun (2024) 15 pp. 3040-3040 [ Pubmed: 38589445 DOI: doi:10.1038/s41467-024-47368-4 ]
- Transcription antitermination protein rfah (18 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase subunit omega (10 kDa, Protein from Escherichia coli)
- Transcription complex (Complex from Escherichia coli)
- Rna (5 kDa, RNA from Escherichia coli)
- Dna and rna (Complex from Escherichia coli)
- Dna-directed rna polymerase subunit alpha (36 kDa, Protein from Escherichia coli)
- Template dna (12 kDa, DNA from Escherichia coli)
- Dna-directed rna polymerase subunit beta (150 kDa, Protein from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase subunit beta' (156 kDa, Protein from Escherichia coli)
- Transcription complex paused at ops site, assembled on not fully complementary nucleic acid scaffold, bound to disulfide-bridged (autoinhibited) rfah (417 kDa, Complex)
- Non-template dna (12 kDa, DNA from Escherichia coli)