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sample_name:"protein E" AND author_name:"Li Y"
Cryo-EM structure of the human ubiquitylated 40S ribosome with RIOK3
Release date: Feb. 12, 2025
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8zdb
Q-score: 0.414
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8zdb
Q-score: 0.414
Huang Z, Diehl FF, Wang M, Li Y, Song A, Chen FX, Rosa-Mercado NA, Beckmann R, Green R, Cheng J
Mol Cell (2025) [ Pubmed: 39947183 DOI: doi:10.1016/j.molcel.2025.01.013 ]
Sample:
- Small ribosomal subunit protein us17 (18 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us9 (16 kDa, Protein from Homo sapiens)
- 18s rrna (602 kDa, RNA from Homo sapiens)
- Small ribosomal subunit protein es6 (28 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us8 (14 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es30 (6 kDa, Protein from Homo sapiens)
- Ubiquitylated 40s ribosome with riok3 (Complex from Homo sapiens)
- Small ribosomal subunit protein es26 (13 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us13 (17 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es10 (18 kDa, Protein from Homo sapiens)
- Serine/threonine-protein kinase rio3 (59 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es7 (22 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es12 (14 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es1 (30 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us14 (6 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us10 (13 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us19 (17 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es4, x isoform (29 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es32 (3 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein rack1 (35 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us11 (16 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es8 (24 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us5 (31 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es28 (7 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es24 (15 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es25 (13 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es19 (16 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Ubiquitin (18 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us2 (32 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us4 (22 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us12 (15 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es17 (15 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us15 (17 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us7 (22 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es21 (9 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es27 (9 kDa, Protein from Homo sapiens)
Cryo-EM structure of the human ubiquitylated pre-40S ribosome with RIOK3
Release date: Feb. 12, 2025
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8zdc
Q-score: 0.368
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8zdc
Q-score: 0.368
Huang Z, Diehl FF, Wang M, Li Y, Song A, Chen FX, Rosa-Mercado NA, Beckmann R, Green R, Cheng J
Mol Cell (2025) [ Pubmed: 39947183 DOI: doi:10.1016/j.molcel.2025.01.013 ]
Sample:
- Small ribosomal subunit protein us17 (18 kDa, Protein from Homo sapiens)
- Rna-binding protein nob1 (46 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us9 (16 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es6 (28 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us8 (14 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us13 (17 kDa, Protein from Homo sapiens)
- Ubiquitylated pre-40s ribosome with riok3 (Complex from Homo sapiens)
- Small ribosomal subunit protein es10 (18 kDa, Protein from Homo sapiens)
- Serine/threonine-protein kinase rio3 (59 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es7 (22 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es12 (14 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es1 (30 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us14 (6 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us10 (13 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us19 (17 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es4, x isoform (29 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein rack1 (35 kDa, Protein from Homo sapiens)
- Protein ltv1 homolog (54 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us11 (16 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es8 (24 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us5 (31 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es28 (7 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es24 (15 kDa, Protein from Homo sapiens)
- Pre-rrna-processing protein tsr1 homolog (91 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es25 (13 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es19 (16 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Small ribosomal subunit protein us2 (32 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us4 (22 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us12 (15 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es17 (15 kDa, Protein from Homo sapiens)
- 18s rrna (604 kDa, RNA from Homo sapiens)
- Small ribosomal subunit protein us15 (17 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us7 (22 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es21 (9 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es27 (9 kDa, Protein from Homo sapiens)
- Rna-binding protein pno1 (27 kDa, Protein from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
Cryo-EM structure of the human ubiquitylated pre-40S ribosome with RIOK3 (without NOB1)
Release date: Feb. 12, 2025
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8zdd
Q-score: 0.396
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8zdd
Q-score: 0.396
Huang Z, Diehl FF, Wang M, Li Y, Song A, Chen FX, Rosa-Mercado NA, Beckmann R, Green R, Cheng J
Mol Cell (2025) [ Pubmed: 39947183 DOI: doi:10.1016/j.molcel.2025.01.013 ]
Sample:
- Small ribosomal subunit protein us17 (18 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us9 (16 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es6 (28 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us8 (14 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us13 (17 kDa, Protein from Homo sapiens)
- Ubiquitylated pre-40s ribosome with riok3 (Complex from Homo sapiens)
- Small ribosomal subunit protein es10 (18 kDa, Protein from Homo sapiens)
- Serine/threonine-protein kinase rio3 (59 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es7 (22 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es12 (14 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es1 (30 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us14 (6 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us10 (13 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us19 (17 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es4, x isoform (29 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein rack1 (35 kDa, Protein from Homo sapiens)
- Protein ltv1 homolog (54 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us11 (16 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es8 (24 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us5 (31 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es28 (7 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es24 (15 kDa, Protein from Homo sapiens)
- Pre-rrna-processing protein tsr1 homolog (91 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es25 (13 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es19 (16 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Small ribosomal subunit protein us2 (32 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us4 (22 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us12 (15 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es17 (15 kDa, Protein from Homo sapiens)
- 18s rrna (604 kDa, RNA from Homo sapiens)
- Small ribosomal subunit protein us15 (17 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us7 (22 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es21 (9 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein es27 (9 kDa, Protein from Homo sapiens)
- Rna-binding protein pno1 (27 kDa, Protein from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
Cryo-EM structure of the yeast 80S ribosome with tigecycline, eEF2, Stm1 and eIF5A
Release date: July 10, 2024
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8k2d
Q-score: 0.423
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8k2d
Q-score: 0.423
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R, Cheng J
Nat Commun (2024) 15 pp. 5481-5481 [ Pubmed: 38942792 DOI: doi:10.1038/s41467-024-49797-7 ]
Sample:
- 40s ribosomal protein s8-a (22 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el39 (6 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us19 (16 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el6a (20 kDa, Protein from Saccharomyces cerevisiae)
- Yeast 80s ribosome (Complex from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el29 (6 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s6-a (27 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es12 (15 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul22a (20 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el27a (15 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s22-a (14 kDa, Protein from Saccharomyces cerevisiae)
- Suppressor protein stm1 (30 kDa, Protein from Saccharomyces cerevisiae)
- 23s rrna (1 MDa, RNA from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul14a (14 kDa, Protein from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- Large ribosomal subunit protein ul11a (17 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el18a (20 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el19a (21 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el34a (13 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s27-a (8 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul15 (16 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us13a (17 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul2a (27 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul23 (15 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el36a (11 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el14a (15 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el31a (12 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el37a (9 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el21a (18 kDa, Protein from Saccharomyces cerevisiae)
- Eukaryotic translation initiation factor 5a-1 (17 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul5a (19 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us2a (28 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es19a (15 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el22a (13 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el20a (20 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es10a (12 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s24-a (15 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s2 (27 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s1-a (28 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us9a (15 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul16 (25 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul13a (22 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul29a (13 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein rack1 (34 kDa, Protein from Saccharomyces cerevisiae)
- Ubiquitin-ribosomal protein es31 fusion protein (17 kDa, Protein from Saccharomyces cerevisiae)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Large ribosomal subunit protein ul6a (21 kDa, Protein from Saccharomyces cerevisiae)
- Ubiquitin-ribosomal protein el40a fusion protein (14 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us10 (13 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el24a (17 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es21a (9 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el43a (10 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el41a (3 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us17a (17 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul1a (24 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s9-a (22 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us14a (6 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Small ribosomal subunit protein es26b (13 kDa, Protein from Saccharomyces cerevisiae)
- 5.8s rrna (50 kDa, RNA from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul4a (39 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el15a (24 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s23-a (16 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el8a (28 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us7 (25 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es25a (12 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el42a (12 kDa, Protein from Saccharomyces cerevisiae)
- 18s rrna (579 kDa, RNA from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el13a (22 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s14-a (14 kDa, Protein from Saccharomyces cerevisiae)
- Elongation factor 2 (93 kDa, Protein from Saccharomyces cerevisiae)
- 5s rrna (38 kDa, RNA from Saccharomyces cerevisiae)
- 40s ribosomal protein s7-a (21 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul30a (27 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el33a (12 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el38 (8 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el30 (11 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul24a (14 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es28a (7 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s30-a (7 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul18 (33 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s4-a (29 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es17a (15 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul3 (43 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el32 (14 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul10 (33 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s13 (17 kDa, Protein from Saccharomyces cerevisiae)
- Tigecycline (587 Da, Ligand)
Cryo-EM structure of the yeast 80S ribosome with tigecycline, Not5 and P-site tRNA
Release date: July 10, 2024
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8k82
Q-score: 0.453
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8k82
Q-score: 0.453
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R, Cheng J
Nat Commun (2024) 15 pp. 5481-5481 [ Pubmed: 38942792 DOI: doi:10.1038/s41467-024-49797-7 ]
Sample:
- 40s ribosomal protein s8-a (22 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el39 (6 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us19 (16 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el6a (20 kDa, Protein from Saccharomyces cerevisiae)
- Yeast 80s ribosome (Complex from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el29 (6 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s6-a (27 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es12 (15 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul22a (20 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el27a (15 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s22-a (14 kDa, Protein from Saccharomyces cerevisiae)
- 23s rrna (1 MDa, RNA from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul14a (14 kDa, Protein from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- Large ribosomal subunit protein ul11a (17 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el18a (20 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el19a (21 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el34a (13 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s27-a (8 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul15 (16 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us13a (17 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul2a (27 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul23 (15 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el36a (11 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el14a (15 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el31a (12 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el37a (9 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el21a (18 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul5a (19 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us2a (28 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es19a (15 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el22a (13 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el20a (20 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es10a (12 kDa, Protein from Saccharomyces cerevisiae)
- Spermidine (145 Da, Ligand)
- General negative regulator of transcription subunit 5 (65 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s24-a (15 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s2 (27 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s1-a (28 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us9a (15 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul16 (25 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul13a (22 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul29a (13 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein rack1 (34 kDa, Protein from Saccharomyces cerevisiae)
- Ubiquitin-ribosomal protein es31 fusion protein (17 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul6a (21 kDa, Protein from Saccharomyces cerevisiae)
- Ubiquitin-ribosomal protein el40a fusion protein (14 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us10 (13 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el24a (17 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es21a (9 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el43a (10 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el41a (3 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us17a (17 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul1a (24 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s9-a (22 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us14a (6 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Small ribosomal subunit protein es26b (13 kDa, Protein from Saccharomyces cerevisiae)
- 5.8s rrna (50 kDa, RNA from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul4a (39 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el15a (24 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s23-a (16 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el8a (28 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us7 (25 kDa, Protein from Saccharomyces cerevisiae)
- Trna (24 kDa, RNA from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es25a (12 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el42a (12 kDa, Protein from Saccharomyces cerevisiae)
- 18s rrna (579 kDa, RNA from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el13a (22 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s14-a (14 kDa, Protein from Saccharomyces cerevisiae)
- 5s rrna (38 kDa, RNA from Saccharomyces cerevisiae)
- 40s ribosomal protein s7-a (21 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul30a (27 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el33a (12 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el38 (8 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el30 (11 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul24a (14 kDa, Protein from Saccharomyces cerevisiae)
- Mrna (935 Da, RNA from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es28a (7 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s30-a (7 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul18 (33 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s4-a (29 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es17a (15 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul3 (43 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el32 (14 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul10 (33 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s13 (17 kDa, Protein from Saccharomyces cerevisiae)
- Tigecycline (587 Da, Ligand)
Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline
Release date: July 10, 2024
Resolution: 2.0 Å
EM Method: Single-particle
Fitted PDBs: 8yoo
Q-score: 0.602
Resolution: 2.0 Å
EM Method: Single-particle
Fitted PDBs: 8yoo
Q-score: 0.602
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R, Cheng J
Nat Commun (2024) 15 pp. 5481-5481 [ Pubmed: 38942792 DOI: doi:10.1038/s41467-024-49797-7 ]
Sample:
- 40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
- 80s ribosome with 100um tigecycline (Complex from Homo sapiens)
- 40s ribosomal protein s18 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3 (26 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 40s ribosomal protein s25 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s2 (31 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s26 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein el40 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s20 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s10 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s30 (6 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l24 (17 kDa, Protein from Homo sapiens)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul10 (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- 18s rrna (602 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
- 40s ribosomal protein sa (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul16 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l12 (17 kDa, Protein from Homo sapiens)
- Receptor of activated protein c kinase 1 (35 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s19 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- Tigecycline (587 Da, Ligand)
Structure of Mycobacterium smegmatis Rsh bound to a 70S translation initiation complex
Release date: May 17, 2023
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8fr8
Q-score: 0.549
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8fr8
Q-score: 0.549
Li Y, Majumdar S, Treen R, Sharma MR, Corro J, Gamper HB, Manjari SR, Prusa J, Banavali NK, Stallings CL, Hou YM, Agrawal RK, Ojha AK
PNAS (2023) 120 pp. e2302006120-e2302006120 [ Pubmed: 37216503 DOI: doi:10.1073/pnas.2302006120 ]
Sample:
- 50s ribosomal protein l21 (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s16 (12 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s5 (18 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l6 (19 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l23 (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s7 (17 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l30 (6 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l5 (20 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l9 (15 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s20 (9 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s17 (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Mycobacterium smegmatis 70s ribosome bound to rsh, and initiator trna-fmet (Complex)
- 23s rrna (3119-mer) (1 MDa, RNA from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l24 (11 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s4 (23 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s6 (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s18 1 (9 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l10 (13 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l13 (16 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l27 (8 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s8 (14 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s15 (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s2 (25 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Mrna (6 kDa, RNA from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s10 (11 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l20 (14 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l17 (13 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l4 (22 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 5s rrna (118-mer) (38 kDa, RNA from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l36 (4 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l31 (9 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l25 (20 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l19 (12 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s13 (13 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s19 (9 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l33 2 (6 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein el31 (2 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Gtp pyrophosphokinase rela (88 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l32 (6 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s11 (12 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l2 (30 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s14 (11 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Fmet trna (77-mer) (24 kDa, RNA from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s3 (23 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l16 (15 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l11 (14 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s12 (13 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l3 (22 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l29 (7 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l14 (13 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l22 (12 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l15 (15 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l28 (8 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l18 (13 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l34 (5 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 50s ribosomal protein l35 (7 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 16s rrna (1511-mer) (490 kDa, RNA from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s22 (4 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- 30s ribosomal protein s9 (14 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
Release date: Aug. 11, 2021
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7mdx
Q-score: 0.363
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7mdx
Q-score: 0.363
Sharma S, Zhou R, Wan L, Feng S, Song K, Xu C, Li Y, Liao M
Nat Commun (2021) 12 pp. 4687- [ DOI: doi:10.1038/s41467-021-24965-1 ]
Sample:
- Lipoprotein-releasing system transmembrane protein lole (44 kDa, Protein from Escherichia coli)
- Lipoprotein-releasing system transmembrane protein lolc (42 kDa, Protein from Escherichia coli)
- (2r)-2-(tridecanoyloxy)propyl hexadecanoate (526 Da, Ligand)
- Pentadecanoic acid (242 Da, Ligand)
- Triacyl-lipoprotein (492 Da, Protein from Escherichia coli)
- Lipoprotein-releasing system atp-binding protein lold (23 kDa, Protein from Escherichia coli)
- Lipo-releasing system transmembrane protein lolc (e.c.3.6.3.-), lipoprotein-releasing system transmembrane protein (e.c.3.6.3.-), lipoprotein-releasing system atp-binding protein lold (e.c.7.6.2.-), triacyl-lipoprotein (130 MDa, Complex from Escherichia coli)