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Structure of the human 48S initiation complex in open state (h48S AUG open)

Release date: May 11, 2022
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7qp6
Q-score: 0.233

Yi SH, Petrychenko V, Schliep JE, Goyal A, Linden A, Chari A, Urlaub H, Stark H, Rodnina MV, Adio S, Fischer N

Nucleic Acids Res (2022) 50 pp. 5282-5298 [ DOI: doi:10.1093/nar/gkac283 Pubmed: 35489072 ]

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Structure of the human 48S initiation complex in closed state (h48S AUG closed)

Release date: May 11, 2022
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7qp7
Q-score: 0.337

Yi SH, Petrychenko V, Schliep JE, Goyal A, Linden A, Chari A, Urlaub H, Stark H, Rodnina MV, Adio S, Fischer N

Nucleic Acids Res (2022) 50 pp. 5282-5298 [ Pubmed: 35489072 DOI: doi:10.1093/nar/gkac283 ]

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Structural basis of Integrator-mediated transcription regulation

Release date: Dec. 8, 2021
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7pks
Q-score: 0.278

Fianu I, Chen Y, Dienemann C, Dybkov O, Linden A, Urlaub H, Cramer P

Science (2021) 374 pp. 883-887 [ DOI: doi:10.1126/science.abk0154 Pubmed: 34762484 ]

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Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 (Map 1)

Release date: July 22, 2020
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6ted
Q-score: 0.338

Vos SM, Farnung L, Linden A, Urlaub H, Cramer P

Nat Struct Mol Biol (2020) 27 pp. 668-677 [ DOI: doi:10.1038/s41594-020-0437-1 Pubmed: 32541898 ]

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Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 (Map A)

Release date: Aug. 22, 2018
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6gmh

Vos SM, Farnung L, Boehning M, Wigge C, Linden A, Urlaub H, Cramer P

Nature (2018) 560 pp. 607-612 [ DOI: doi:10.1038/s41586-018-0440-4 Pubmed: 30135578 ]

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