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sample_name:"subunit-d" AND xref_links:"go" AND film_detector_model:"FEI FALCON III (4K X 4K)"
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PolII-TCR-STK19 structure.

Release date: Dec. 4, 2024
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9er2
Q-score: 0.448

van den Heuvel D, Rodriguez-Martinez M, van der Meer PJ, Nieto Moreno N, Park J, Kim HS, van Schie JJM, Wondergem AP, D'Souza A, Yakoub G, Herlihy AE, Kashyap K, Boissiere T, Walker J, Mitter R, Apelt K, de Lint K, Kirdok I, Ljungman M, Wolthuis RMF, Cramer P, Scharer OD, Kokic G, Svejstrup JQ, Luijsterburg MS

Cell (2024) 187 pp. 7107- [ DOI: doi:10.1016/j.cell.2024.10.018 Pubmed: 39547229 ]

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Structure of human 48S translation initiation complex in open codon scanning state (48S-1)

Release date: Aug. 14, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8pj1
Q-score: 0.368

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2024) [ Pubmed: 39289545 DOI: doi:10.1038/s41594-024-01378-4 ]

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Structure of human 48S translation initiation complex in AUG recognition state after eIF5-induced GTP hydrolysis by eIF2 (48S-2)

Release date: Aug. 14, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8pj2
Q-score: 0.32

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2024) [ Pubmed: 39289545 DOI: doi:10.1038/s41594-024-01378-4 ]

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Structure of human 48S translation initiation complex upon transfer of initiator tRNA to eIF5B (48S-3)

Release date: Aug. 14, 2024
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8pj3
Q-score: 0.312

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2024) [ Pubmed: 39289545 DOI: doi:10.1038/s41594-024-01378-4 ]

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Structure of human 48S translation initiation complex after eIF5 release (48S-4)

Release date: Aug. 14, 2024
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8pj4
Q-score: 0.361

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2025) 32 pp. 62-72 [ Pubmed: 39289545 DOI: doi:10.1038/s41594-024-01378-4 ]

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Structure of human 48S translation initiation complex after eIF2 release prior 60S subunit joining (48S-5)

Release date: Aug. 14, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8pj5
Q-score: 0.437

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2024) [ Pubmed: 39289545 DOI: doi:10.1038/s41594-024-01378-4 ]

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Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3 (off-pathway)

Release date: Aug. 14, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8pj6
Q-score: 0.374

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2024) [ Pubmed: 39289545 DOI: doi:10.1038/s41594-024-01378-4 ]

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Structure of human eIF3 core from closed 48S translation initiation complex

Release date: Aug. 14, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8rg0
Q-score: 0.303

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2025) 32 pp. 62-72 [ Pubmed: 39289545 DOI: doi:10.1038/s41594-024-01378-4 ]

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Structure of the human 48S initiation complex in open state (h48S AUG open)

Release date: May 11, 2022
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7qp6
Q-score: 0.233

Yi SH, Petrychenko V, Schliep JE, Goyal A, Linden A, Chari A, Urlaub H, Stark H, Rodnina MV, Adio S, Fischer N

Nucleic Acids Res (2022) 50 pp. 5282-5298 [ Pubmed: 35489072 DOI: doi:10.1093/nar/gkac283 ]

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Structure of the human 48S initiation complex in closed state (h48S AUG closed)

Release date: May 11, 2022
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7qp7
Q-score: 0.337

Yi SH, Petrychenko V, Schliep JE, Goyal A, Linden A, Chari A, Urlaub H, Stark H, Rodnina MV, Adio S, Fischer N

Nucleic Acids Res (2022) 50 pp. 5282-5298 [ Pubmed: 35489072 DOI: doi:10.1093/nar/gkac283 ]

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