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sample_name:"subunit-d" AND xref_links:"pdb" AND natural_source_ncbi_code:"32630"
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Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex

Release date: July 31, 2024
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8a3y
Q-score: 0.231

Farnung L, Ochmann M, Garg G, Vos SM, Cramer P

Mol Cell (2022) 82 pp. 3126-3134.e7 [ Pubmed: 35858621 DOI: doi:10.1016/j.molcel.2022.06.027 ]

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Cryo-EM structure of Thermococcus kodakarensis FttA-dependent transcription pre-termination complex containing 44 nt RNA

Release date: July 31, 2024
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 9bct
Q-score: 0.554

You L, Wang C, Molodtsov V, Kuznedelov K, Miao X, Wenck BR, Ulisse P, Sanders TJ, Marshall CJ, Firlar E, Kaelber JT, Santangelo TJ, Ebright RH

Nature (2024) 635 pp. 229-236 [ DOI: doi:10.1038/s41586-024-07979-9 Pubmed: 39322680 ]

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Cryo-EM structure of Thermococcus kodakarensis FttA-dependent transcription pre-termination complex containing 52 nt RNA

Release date: July 31, 2024
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 9bcu
Q-score: 0.613

You L, Wang C, Molodtsov V, Kuznedelov K, Miao X, Wenck BR, Ulisse P, Sanders TJ, Marshall CJ, Firlar E, Kaelber JT, Santangelo TJ, Ebright RH

Nature (2024) 635 pp. 229-236 [ DOI: doi:10.1038/s41586-024-07979-9 Pubmed: 39322680 ]

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Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex

Release date: Feb. 7, 2024
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8rbx
Q-score: 0.037

Fianu I, Ochmann M, Walshe JL, Dybkov O, Cruz JN, Urlaub H, Cramer P

Nature (2024) 629 pp. 219-227 [ Pubmed: 38570683 DOI: doi:10.1038/s41586-024-07269-4 ]

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Structure of the mammalian Pol II-SPT6 complex (composite map)

Release date: Oct. 18, 2023
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8oeu
Q-score: 0.526

Structure of the mammalian Pol II-SPT6-Elongin complex, lacking ELOA latch (composite map 2)

Release date: Oct. 18, 2023
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8oev
Q-score: 0.468

Chen Y, Kokic G, Dienemann C, Dybkov O, Urlaub H, Cramer P

Nat Struct Mol Biol (2023) 30 pp. 1925-1935 [ DOI: doi:10.1038/s41594-023-01138-w Pubmed: 37932450 ]

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Structure of the mammalian Pol II-Elongin complex, lacking the ELOA latch (composite map 1 for structure 2)

Release date: Oct. 18, 2023
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8oew
Q-score: 0.56

Chen Y, Kokic G, Dienemann C, Dybkov O, Urlaub H, Cramer P

Nat Struct Mol Biol (2023) 30 pp. 1925-1935 [ DOI: doi:10.1038/s41594-023-01138-w Pubmed: 37932450 ]

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Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1 (local resolution filtered map)

Release date: Oct. 18, 2023
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 8of0
Q-score: 0.422

Chen Y, Kokic G, Dienemann C, Dybkov O, Urlaub H, Cramer P

Nat Struct Mol Biol (2023) 30 pp. 1925-1935 [ DOI: doi:10.1038/s41594-023-01138-w Pubmed: 37932450 ]

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Structure of mammalian Pol II-TFIIS elongation complex

Release date: Aug. 23, 2023
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8a40
Q-score: 0.486

Structural insights into human co-transcriptional capping - structure 1

Release date: Aug. 16, 2023
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8p4a
Q-score: 0.344
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