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sample_name:"transporter2" AND author_orcid:"0000-0002-2432-4283"
Cryo-EM structure of human apo VMAT2 with nanobody in an outward-facing conformation
Release date: June 12, 2024
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8wlj
Q-score: 0.374
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8wlj
Q-score: 0.374
To Be Published
Sample:
- Nanobody (13 kDa, Protein from Vicugna pacos)
- Nanobody (Complex from Vicugna pacos)
- Synaptic vesicular amine transporter (53 kDa, Protein from Homo sapiens)
- Vmat2 (Complex from Homo sapiens)
- Vesicular monoamine transporter 2 (Complex)
Release date: June 12, 2024
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 8wlk
Q-score: 0.424
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 8wlk
Q-score: 0.424
To Be Published
Release date: June 12, 2024
Resolution: 3.74 Å
EM Method: Single-particle
Fitted PDBs: 8wll
Q-score: 0.353
Resolution: 3.74 Å
EM Method: Single-particle
Fitted PDBs: 8wll
Q-score: 0.353
To Be Published
Sample:
- Reserpine (608 Da, Ligand)
- Complex of vesicular monoamine transporter 2 and reserpine (Complex from Homo sapiens)
- Synaptic vesicular amine transporter (53 kDa, Protein from Homo sapiens)
Cryo-EM structure of human VMAT2 in presence of 5-HT, determined in an outward-facing conformation
Release date: June 12, 2024
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 8wlm
Q-score: 0.404
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 8wlm
Q-score: 0.404
To Be Published
Sample:
- Complex of vesicular monoamine transporter 2 with 5-ht (Complex from Homo sapiens)
- Synaptic vesicular amine transporter (53 kDa, Protein from Homo sapiens)
- Serotonin (176 Da, Ligand)