human NaS1 intermediate state 2
Resolution: 2.73 Å
EM Method: Single-particle
Fitted PDBs: 8y5w
Q-score: 0.579
Chen X, Zhang Y, Yin J, Liu C, Xie M, Wang Y, Chen M, Zhang R, Yuan X, Li D, Chen X, Gao X, Cai G, Zhang S, Zhou B, Yang M
Sci Adv (2024) 10 pp. eado6778-eado6778 [ Pubmed: 39576865 DOI: doi:10.1126/sciadv.ado6778 ]
- Sodium ion (22 Da, Ligand)
- Sulfate ion (96 Da, Ligand)
- Membrane sodium anion transproter 2 (Complex from Homo sapiens)
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
human NaS1 intermediate state 3
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8y5x
Q-score: 0.484
Chen X, Zhang Y, Yin J, Liu C, Xie M, Wang Y, Chen M, Zhang R, Yuan X, Li D, Chen X, Gao X, Cai G, Zhang S, Zhou B, Yang M
Sci Adv (2024) 10 pp. eado6778-eado6778 [ DOI: doi:10.1126/sciadv.ado6778 Pubmed: 39576865 ]
- Membrane sodium anion transproter 3 (Cellular component from Homo sapiens)
- Sodium ion (22 Da, Ligand)
- Sulfate ion (96 Da, Ligand)
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
Chen X, Zhang Y, Yin J, Liu C, Xie M, Wang Y, Chen M, Zhang R, Yuan X, Li D, Chen X, Gao X, Cai G, Zhang S, Zhou B, Yang M
Sci Adv (2024) 10 pp. eado6778-eado6778 [ DOI: doi:10.1126/sciadv.ado6778 Pubmed: 39576865 ]
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
- Sulfate ion (96 Da, Ligand)
- Membrane sodium anion transproter out (Complex from Homo sapiens)
Chen X, Zhang Y, Yin J, Liu C, Xie M, Wang Y, Chen M, Zhang R, Yuan X, Li D, Chen X, Gao X, Cai G, Zhang S, Zhou B, Yang M
Sci Adv (2024) 10 pp. eado6778-eado6778 [ DOI: doi:10.1126/sciadv.ado6778 Pubmed: 39576865 ]
- Sodium ion (22 Da, Ligand)
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
- Sulfate ion (96 Da, Ligand)
- Membrane sodium anion transproter in (Complex from Homo sapiens)
He J, Liu G, Kong F, Tan Q, Wang Z, Yang M, He Y, Jia X, Yan C, Wang C, Qian H
Cell Rep (2024) 43 pp. 114628-114628 [ DOI: doi:10.1016/j.celrep.2024.114628 Pubmed: 39146184 ]
- Cryo-em structure of oat4 (Cell from Homo sapiens)
- Chloride ion (35 Da, Ligand)
- Solute carrier family 22 member 11 (56 kDa, Protein from Homo sapiens)
Cryo-EM structure of URAT1(R477S)-Urate complex
He J, Liu G, Kong F, Tan Q, Wang Z, Yang M, He Y, Jia X, Yan C, Wang C, Qian H
Cell Rep (2024) 43 pp. 114628-114628 [ DOI: doi:10.1016/j.celrep.2024.114628 Pubmed: 39146184 ]
- Solute carrier family 22 member 12 (58 kDa, Protein from Homo sapiens)
- Uric acid (168 Da, Ligand)
- Cryo-em structure of urat1(r477s)-urate complex (Complex from Homo sapiens)
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 8ghk
Q-score: 0.507
Nagashima KA, Dzimianski JV, Yang M, Abendroth J, Sautto GA, Ross TM, DuBois RM, Edwards TE, Mousa JJ
Structure (2024) 32 pp. 1079- [ Pubmed: 38810648 DOI: doi:10.1016/j.str.2024.05.001 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Gs10-x6-be4 fab heavy chain (16 kDa, Protein from Homo sapiens)
- Hemagglutinin (53 kDa, Protein from Influenza A virus)
- Cryoem structure of influenza a virus a/melbourner/1/1946 (h1n1) hemagglutinin bound to gs10-x6-be4 fab (221 kDa, Complex)
- Gs10-x6-be4 fab light chain (13 kDa, Protein from Homo sapiens)
Structure of BtKY72 spike receptor-binding domain (RBD) complexed with bat ACE2
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8k4u
Q-score: 0.479
Su C, He J, Wang L, Hu Y, Cao J, Bai B, Qi J, Gao GF, Yang M, Wang Q
Mbio (2024) 15 pp. e0140424-e0140424 [ DOI: doi:10.1128/mbio.01404-24 Pubmed: 39082798 ]
- Btky72 (25 kDa, Protein from Severe acute respiratory syndrome-related coronavirus)
- Zinc ion (65 Da, Ligand)
- Ace2 (69 kDa, Protein from Rhinolophus landeri)
- Bat ace2 (Complex)
- Btky72 rbd (Complex from Rhinolophus landeri)
- Structure of btky72 spike receptor-binding domain (rbd) complexed with bat ace2 (Complex from Severe acute respiratory syndrome-related coronavirus)
Structure of synaptic vesicle protein 2B with padsevonil
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8uo8
Q-score: 0.474
Mittal A, Martin MF, Levin EJ, Adams C, Yang M, Provins L, Hall A, Procter M, Ledecq M, Hillisch A, Wolff C, Gillard M, Horanyi PS, Coleman JA
Nat Struct Mol Biol (2024) 31 pp. 1964-1974 [ Pubmed: 38898101 DOI: doi:10.1038/s41594-024-01335-1 ]
- Synaptic vesicle glycoprotein 2b (77 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- [(2r)-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-2-propanoyloxy-propyl] propanoate (370 Da, Ligand)
- (4r)-4-(2-chloro-2,2-difluoroethyl)-1-{[(4r)-2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl}pyrrolidin-2-one (432 Da, Ligand)
- 1,2-didecanoyl-sn-glycero-3-[phospho-l-serine] (566 Da, Ligand)
- Sv2b complexed with padsevonil (77 MDa, Complex from Homo sapiens)
- (3beta,14beta,17beta,25r)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en (544 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Water (18 Da, Ligand)
Structure of synaptic vesicle protein 2A in complex with a nanobody
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8uo9
Q-score: 0.318
Mittal A, Martin MF, Levin EJ, Adams C, Yang M, Provins L, Hall A, Procter M, Ledecq M, Hillisch A, Wolff C, Gillard M, Horanyi PS, Coleman JA
Nat Struct Mol Biol (2024) 31 pp. 1964-1974 [ Pubmed: 38898101 DOI: doi:10.1038/s41594-024-01335-1 ]
- (4s)-1-{[(4s)-2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl}-4-(4,4,4-trifluorobutyl)pyrrolidin-2-one (444 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Protein with a nanobody (98 MDa, Complex from Homo sapiens)
- Nanobody (15 kDa, Protein from Lama glama)
- Synaptic vesicle glycoprotein 2a (75 kDa, Protein from Homo sapiens)
- 1,2-didecanoyl-sn-glycero-3-[phospho-l-serine] (566 Da, Ligand)