Human 26S proteasome in complex with Oprozomib
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 5m32
Q-score: 0.404
Haselbach D, Schrader J, Lambrecht F, Henneberg F, Chari A, Stark H
Nat Commun (2017) 8 pp. 15578-15578 [ Pubmed: 28541292 DOI: doi:10.1038/ncomms15578 ]
- Proteasome subunit beta type-1 (26 kDa, Protein from Human)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 26s protease regulatory subunit 6a (49 kDa, Protein from Human)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Human)
- Proteasome subunit beta type-3 (22 kDa, Protein from Human)
- 26s protease regulatory subunit 10b (43 kDa, Protein from Human)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Human)
- Bound oprozomib (Complex from Synthetic construct)
- Proteasome subunit alpha type-1 (26 kDa, Protein from Human)
- Proteasome subunit beta type-4 (29 kDa, Protein from Human)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Human)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Human)
- 26s protease regulatory subunit 8 (39 kDa, Protein from Human)
- Proteasome subunit alpha type-1 (26 kDa, Protein from Human)
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Human)
- Proteasome subunit beta type-6 (25 kDa, Protein from Human)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Human)
- Human 26s proteasome (Complex from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 3 (61 kDa, Protein from Human)
- Proteasome subunit beta type-5 (22 kDa, Protein from Human)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Human)
- 26s proteasome complex subunit sem1 (8 kDa, Protein from Human)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Human)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Human)
- 26s protease regulatory subunit 6b (47 kDa, Protein from Human)
- Human 26s proteasome in complex with oprozomib (1 MDa, Complex)
- Proteasome subunit alpha type-7 (26 kDa, Protein from Human)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Human)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Human)
- 26s protease regulatory subunit 4 (47 kDa, Protein from Human)
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Human)
- Bound oprozomib (536 Da, Protein from Synthetic construct)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Human)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Human)
- Proteasome subunit beta type-2 (22 kDa, Protein from Human)
- Proteasome subunit alpha type-7 (26 kDa, Protein from Human)
- 26s protease regulatory subunit 7 (48 kDa, Protein from Human)
- Proteasome subunit beta type-7 (30 kDa, Protein from Human)