EMPIAR-11041

Cryo electron-microscopy of TMEM106B fibrils extracted from four FTLD-TDP patient brains

Entry authors:
Jiang YX , Cao Q , Sawaya MR , Abskharon R, Ge P , DeTure M, Dickson DW, Fu JY, Ogorzalek Loo RR, Loo JA, Eisenberg DS 
Publication:
Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43
Jiang YX, Cao Q, Sawaya MR , Abskharon R, Ge P , DeTure M, Dickson DW , Fu JY , Loo RR, Loo JA , Eisenberg DS 
Nature (2022)
PMID: 35344984
Experiment type:
EMDB
Related PDB entries:
Related EMDB entries:
.EMD-24953 (2.9Å), EMD-24954 (3.2Å), EMD-24955 (3.7Å)
Deposited:
2022-04-08
Released:
2022-05-27
Last modified:
2022-05-30
Dataset size:
3.4 TB
Experimental metadata:
Contains:
micrographs
Image not available

Image sets

1. Unaligned multi-frame micrographs of TMEM106B amyloid fibrils extracted from FTLD-TDP donor 1
Category:micrographs - multiframe
Image format:TIFF
No. of images or tilt series:4079
Frames per image:36
Pixel type:UNSIGNED BYTE
Details:
.Pixel size: 1.1 A/pixel, dose rate: ~1 e/A^2/frame
2. Unaligned multi-frame micrographs of TMEM106B amyloid fibrils extracted from FTLD-TDP donor 2
Category:micrographs - multiframe
Image format:TIFF
No. of images or tilt series:2026
Frames per image:36
Pixel type:UNSIGNED BYTE
Details:
.Pixel size: 1.1 A/pixel, dose rate: ~1 e/A^2/frame
3. Unaligned multi-frame micrographs of TMEM106B amyloid fibrils extracted from FTLD-TDP donor 3
Category:micrographs - multiframe
Image format:TIFF
No. of images or tilt series:2043
Frames per image:36
Pixel type:UNSIGNED BYTE
Details:
.Pixel size: 1.1 A/pixel, dose rate: ~1 e/A^2/frame
4. Unaligned multi-frame micrographs of TMEM106B amyloid fibrils extracted from FTLD-TDP donor 4
Category:micrographs - multiframe
Image format:TIFF
No. of images or tilt series:1069
Frames per image:36
Pixel type:UNSIGNED BYTE
Details:
.Pixel size: 1.1 A/pixel, dose rate: ~1 e/A^2/frame
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