EMPIAR-11869 Single particle Cryo EM of the LRRK2 I2020T mutant bound to GZD-824

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EMPIAR-11869

Single particle Cryo EM of the LRRK2 I2020T mutant bound to GZD-824

Entry authors:

Villagran Suarez A , Leschziner A

Publication:

Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures

Sanz Murillo M , Villagran Suarez A , Dederer V , Chatterjee D, Alegrio Louro J , Knapp S , Mathea S , Leschziner AE

Sci Adv 9 (2023)

DOI: 10.1126/sciadv.adk6191

Experiment type:

EMDB

Related PDB entry:

Related EMDB entry:

EMD-41757 (3.4Å)

Deposited:

2024-01-23

Released:

2024-02-08

Last modified:

2024-02-08

Dataset size:

4.6 TB

Dataset DOI:

10.6019/EMPIAR-11869

Funding:

1. Michael J. Fox Foundation

ASAP-000519

United States

Experimental metadata:

Contains:

micrographs

Image not available

Image set

1. Unaligned multiframe micrographs

Category:micrographs - multiframe

Image format:EER

No. of images or tilt series:4102

Frames per image:40

Pixel type:UNSIGNED 16 BIT INTEGER

Pixel spacing:(0.95 Å, 0.95 Å)

Details:

Contains data collected from 1 grids.

data 4.6 TB

XAvailable download options:

Browse All Files

11869 4.6 TB

License:

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