EMPIAR-11191 cryoEM structure of Gq-coupled MRGPRX1 with Compound-16

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EMPIAR-11191

cryoEM structure of Gq-coupled MRGPRX1 with Compound-16

Entry authors:

Liu Y , Cao C , Huang XP, Gumpper RH, Rachman MM, Shih SL , Krumm BE , Zhang S , Shoichet BK , Fay JF , Roth BL

Publication:

Ligand recognition and allosteric modulation of the human MRGPRX1 receptor

Liu Y , Cao C , Huang XP, Gumpper RH, Rachman MM, Shih SL , Krumm BE , Zhang S , Shoichet BK , Fay JF , Roth BL

Nat Chem Biol (2022)

DOI: 10.1038/s41589-022-01173-6

Experiment type:

EMDB

Related PDB entries:

8dwg, 8dwc, 8dwh

Related EMDB entries:

EMD-27753 (2.71Å), EMD-27752 (2.87Å), EMD-27754 (3.25Å)

Deposited:

2022-08-30

Released:

2022-10-31

Last modified:

2022-10-31

Dataset size:

288.1 GB

Dataset DOI:

10.6019/EMPIAR-11191

Experimental metadata:

Contains:

micrographs

Image not available

Image set

1. Aligned multi-frame micrographs

Category:micrographs - single frame

Image format:MRC

No. of images or tilt series:3281

Image size:(5760, 4092)

Pixel type:32 BIT FLOAT

Pixel spacing:(0.88 Å, 0.88 Å)

Details:

The micrographs are dose weighted motion corrected with a total electron exposure of 43.8e/A2

data 288.1 GB

XAvailable download options:

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11191 288.1 GB

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