ID AAR31633; SV 1; linear; genomic DNA; STD; VRL; 1122 BP. XX PA AY446894.2 XX DT 23-DEC-2003 (Rel. 78, Created) DT 03-JUL-2013 (Rel. 117, Last updated, Version 16) XX DE Human betaherpesvirus 5 (Human cytomegalovirus) capsid scaffold protein XX KW . XX OS Human betaherpesvirus 5 (Human cytomegalovirus) OC Viruses; Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus. XX RN [1] RX DOI; 10.1099/vir.0.18856-0. RX PUBMED; 12604818. RA Davison A.J., Akter P., Cunningham C., Dolan A., Addison C., Dargan D.J., RA Hassan-Walker A.F., Emery V.C., Griffiths P.D., Wilkinson G.W.; RT "Homology between the human cytomegalovirus RL11 gene family and human RT adenovirus E3 genes"; RL J. Gen. Virol. 84(Pt 3):657-663(2003). XX RN [2] RX DOI; 10.1099/vir.0.18952-0. RX PUBMED; 12692276. RA Akter P., Cunningham C., McSharry B.P., Dolan A., Addison C., Dargan D.J., RA Hassan-Walker A.F., Emery V.C., Griffiths P.D., Wilkinson G.W., RA Davison A.J.; RT "Two novel spliced genes in human cytomegalovirus"; RL J. Gen. Virol. 84(Pt 5):1117-1122(2003). XX RN [3] RX DOI; 10.1099/vir.0.19298-0. RX PUBMED; 12917473. RA McSharry B.P., Tomasec P., Neale M.L., Wilkinson G.W.; RT "The most abundantly transcribed human cytomegalovirus gene (beta 2.7) is RT non-essential for growth in vitro"; RL J. Gen. Virol. 84(Pt 9):2511-2516(2003). XX RN [4] RX DOI; 10.1099/vir.0.79888-0. RX PUBMED; 15105547. RA Dolan A., Cunningham C., Hector R.D., Hassan-Walker A.F., Lee L., RA Addison C., Dargan D.J., McGeoch D.J., Gatherer D., Emery V.C., RA Griffiths P.D., Sinzger C., McSharry B.P., Wilkinson G.W., Davison A.J.; RT "Genetic content of wild-type human cytomegalovirus"; RL J. Gen. Virol. 85(Pt 5):1301-1312(2004). XX RN [5] RX DOI; 10.1073/pnas.1115861108. RX PUBMED; 22109557. RA Gatherer D., Seirafian S., Cunningham C., Holton M., Dargan D.J., RA Baluchova K., Hector R.D., Galbraith J., Herzyk P., Wilkinson G.W., RA Davison A.J.; RT "High-resolution human cytomegalovirus transcriptome"; RL Proc. Natl. Acad. Sci. U.S.A. 108(49):19755-19760(2011). XX RN [6] RC Consensus viral genome sequence in the original urine sample confirmed from RC Illumina data as being identical, except for the mutation at 176311 RA Wilkie G.S., Davison A.J., Stanton R.J., Wilkinson G.W.G.; RT "Direct Submission"; RL Unpublished. XX RN [7] RA Davison A.J., Akter P., Cunningham C., Dolan A., Addison C., Dargan D.J., RA Hassan-Walker A.F., Emery V.C., Griffiths P.D., Wilkinson G.W.; RT ; RL Submitted (27-SEP-2002) to the INSDC. RL MRC Virology Unit, Church Street, Glasgow G11 5JR, UK XX RN [8] RA Akter P., Cunningham C., McSharry B.P., Dolan A., Addison C., Dargan D.J., RA Hassan-Walker A.F., Emery V.C., Griffiths P.D., Wilkinson G.W., RA Davison A.J.; RT ; RL Submitted (29-OCT-2002) to the INSDC. RL MRC Virology Unit, Church Street, Glasgow G11 5JR, UK XX RN [9] RA McSharry B.P., Tomasec P., Neale M.L., Wilkinson G.W.; RT ; RL Submitted (18-JUN-2003) to the INSDC. RL Infection and Immunity, University of Wales College of Medicine, Tenovus RL Building, Heath Park, Cardiff CF14 4XX, UK XX RN [10] RA Davison A.J.; RT ; RL Submitted (22-OCT-2003) to the INSDC. RL MRC Virology Unit, Church Street, Glasgow G11 5JR, UK XX RN [11] RC Sequence update by submitter RA Davison A.J.; RT ; RL Submitted (13-AUG-2007) to the INSDC. RL MRC Virology Unit, Church Street, Glasgow G11 5JR, UK XX DR MD5; c3ac5c1643bdde87624883f4fb2d7daa. XX FH Key Location/Qualifiers FH FT source 1..1122 FT /organism="Human betaherpesvirus 5" FT /host="Homo sapiens" FT /strain="Merlin" FT /mol_type="genomic DNA" FT /country="United Kingdom:Cardiff" FT /isolation_source="urine from a congenitally infected FT child" FT /collected_by="Gavin W.G. Wilkinson" FT /collection_date="1999" FT /db_xref="taxon:10359" FT /culture_collection="ATCC:VR-1590" FT CDS AY446894.2:117505..118626 FT /codon_start=1 FT /gene="UL80.5" FT /locus_tag="HHV5wtgp075" FT /product="capsid scaffold protein" FT /note="clipped near C terminus; involved in capsid FT morphogenesis" FT /db_xref="GOA:Q6SW62" FT /db_xref="InterPro:IPR001847" FT /db_xref="InterPro:IPR035443" FT /db_xref="UniProtKB/Swiss-Prot:Q6SW62" FT /protein_id="AAR31633.1" FT /translation="MSHPLSAAVPAATAPPGATVAGASPAVSSLAWPHDGVYLPKDAFF FT SLLGASRSAAPVMYPGAVAAPPSASPAPLPLPSYPASYGAPVVGYDQLAARHFADYVDP FT HYPGWGRRYEPAPSLHPSYPVPPPPSPAYYRRRDSPGGMDEPPSGWERYDGGHRGQSQK FT QHRHGGSGGHNKRRKETAAASSSSSDEDLSFPGEAEHGRARKRLKSHVNSDGGSGGHAG FT SNQQQQQRYDELRDAIHELKRDLFAARQSSTLLSAALPSAASSSPTTTTVCTPTSELTS FT GGGETPTALLSGGAKVAERAQAGVVNASCRLATASGSEAATAGPSTAGSSSCPASVVLA FT AAAAQAAAASQSPPKDMVDLNRRIFVAALNKLE" XX SQ Sequence 1122 BP; 187 A; 372 C; 339 G; 224 T; 0 other; atgtcgcacc ctctgagtgc tgcggttccc gccgctacgg ctcctccagg tgctaccgtg 60 gcaggtgcgt cgccggctgt gtcgtctcta gcgtggcctc acgacggagt ttatttaccc 120 aaagacgctt ttttctcgct acttggggcc agtcgctcgg cagcgcccgt catgtatccc 180 ggcgccgtag cggcccctcc ttctgcttcg ccagcaccgc tgcctttgcc gtcttatccc 240 gcgtcctacg gcgcccccgt cgtgggttac gaccagttgg cggcacgtca ctttgcggac 300 tacgtggatc cccattatcc cgggtggggt cggcgttacg agcccgcgcc gtctttgcat 360 ccgtcttatc ccgtgccgcc gccaccatca ccggcctatt accgtcggcg cgactctccg 420 ggcggtatgg atgaaccacc gtccggatgg gagcgttacg acggtggtca ccgtggtcag 480 tcgcagaagc agcaccgtca cgggggcagc ggcggacaca acaaacgccg taaggaaacc 540 gcggcggcgt cgtcgtcgtc ctcggacgaa gacttgagtt tcccaggcga ggccgagcac 600 ggccgggcac gaaagcgtct aaaaagtcac gtcaatagcg acggtggaag tggcgggcac 660 gcgggttcca atcagcagca gcaacaacgt tacgatgaac tgcgggatgc cattcacgag 720 ctgaaacgcg atctgtttgc cgcgcggcag agttctacgt tactttcggc ggctctcccc 780 tctgcggcct cttcctcccc aactactact accgtgtgta ctcccaccag cgagctgacg 840 agtggcggag gagaaacacc cacggcactt ctatccggag gtgccaaggt agctgagcgc 900 gctcaggccg gcgtggtgaa cgccagttgc cgcctcgcta ccgcgtcggg ttctgaggcg 960 gcaacggccg ggccctcgac ggcaggttct tcttcctgcc cggctagtgt cgtgttagcc 1020 gccgctgctg cccaagccgc cgcagcttcc cagagcccgc ccaaagacat ggtagatctg 1080 aatcggcgga tttttgtggc tgcgctcaat aagctcgagt aa 1122 //