ID   AAR31633; SV 1; linear; genomic DNA; STD; VRL; 1122 BP.
XX
PA   AY446894.2
XX
DT   23-DEC-2003 (Rel. 78, Created)
DT   03-JUL-2013 (Rel. 117, Last updated, Version 16)
XX
DE   Human betaherpesvirus 5 (Human cytomegalovirus) capsid scaffold protein
XX
KW   .
XX
OS   Human betaherpesvirus 5 (Human cytomegalovirus)
OC   Viruses; Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
XX
RN   [1]
RX   DOI; 10.1099/vir.0.18856-0.
RX   PUBMED; 12604818.
RA   Davison A.J., Akter P., Cunningham C., Dolan A., Addison C., Dargan D.J.,
RA   Hassan-Walker A.F., Emery V.C., Griffiths P.D., Wilkinson G.W.;
RT   "Homology between the human cytomegalovirus RL11 gene family and human
RT   adenovirus E3 genes";
RL   J. Gen. Virol. 84(Pt 3):657-663(2003).
XX
RN   [2]
RX   DOI; 10.1099/vir.0.18952-0.
RX   PUBMED; 12692276.
RA   Akter P., Cunningham C., McSharry B.P., Dolan A., Addison C., Dargan D.J.,
RA   Hassan-Walker A.F., Emery V.C., Griffiths P.D., Wilkinson G.W.,
RA   Davison A.J.;
RT   "Two novel spliced genes in human cytomegalovirus";
RL   J. Gen. Virol. 84(Pt 5):1117-1122(2003).
XX
RN   [3]
RX   DOI; 10.1099/vir.0.19298-0.
RX   PUBMED; 12917473.
RA   McSharry B.P., Tomasec P., Neale M.L., Wilkinson G.W.;
RT   "The most abundantly transcribed human cytomegalovirus gene (beta 2.7) is
RT   non-essential for growth in vitro";
RL   J. Gen. Virol. 84(Pt 9):2511-2516(2003).
XX
RN   [4]
RX   DOI; 10.1099/vir.0.79888-0.
RX   PUBMED; 15105547.
RA   Dolan A., Cunningham C., Hector R.D., Hassan-Walker A.F., Lee L.,
RA   Addison C., Dargan D.J., McGeoch D.J., Gatherer D., Emery V.C.,
RA   Griffiths P.D., Sinzger C., McSharry B.P., Wilkinson G.W., Davison A.J.;
RT   "Genetic content of wild-type human cytomegalovirus";
RL   J. Gen. Virol. 85(Pt 5):1301-1312(2004).
XX
RN   [5]
RX   DOI; 10.1073/pnas.1115861108.
RX   PUBMED; 22109557.
RA   Gatherer D., Seirafian S., Cunningham C., Holton M., Dargan D.J.,
RA   Baluchova K., Hector R.D., Galbraith J., Herzyk P., Wilkinson G.W.,
RA   Davison A.J.;
RT   "High-resolution human cytomegalovirus transcriptome";
RL   Proc. Natl. Acad. Sci. U.S.A. 108(49):19755-19760(2011).
XX
RN   [6]
RC   Consensus viral genome sequence in the original urine sample confirmed from
RC   Illumina data as being identical, except for the mutation at 176311
RA   Wilkie G.S., Davison A.J., Stanton R.J., Wilkinson G.W.G.;
RT   "Direct Submission";
RL   Unpublished.
XX
RN   [7]
RA   Davison A.J., Akter P., Cunningham C., Dolan A., Addison C., Dargan D.J.,
RA   Hassan-Walker A.F., Emery V.C., Griffiths P.D., Wilkinson G.W.;
RT   ;
RL   Submitted (27-SEP-2002) to the INSDC.
RL   MRC Virology Unit, Church Street, Glasgow G11 5JR, UK
XX
RN   [8]
RA   Akter P., Cunningham C., McSharry B.P., Dolan A., Addison C., Dargan D.J.,
RA   Hassan-Walker A.F., Emery V.C., Griffiths P.D., Wilkinson G.W.,
RA   Davison A.J.;
RT   ;
RL   Submitted (29-OCT-2002) to the INSDC.
RL   MRC Virology Unit, Church Street, Glasgow G11 5JR, UK
XX
RN   [9]
RA   McSharry B.P., Tomasec P., Neale M.L., Wilkinson G.W.;
RT   ;
RL   Submitted (18-JUN-2003) to the INSDC.
RL   Infection and Immunity, University of Wales College of Medicine, Tenovus
RL   Building, Heath Park, Cardiff CF14 4XX, UK
XX
RN   [10]
RA   Davison A.J.;
RT   ;
RL   Submitted (22-OCT-2003) to the INSDC.
RL   MRC Virology Unit, Church Street, Glasgow G11 5JR, UK
XX
RN   [11]
RC   Sequence update by submitter
RA   Davison A.J.;
RT   ;
RL   Submitted (13-AUG-2007) to the INSDC.
RL   MRC Virology Unit, Church Street, Glasgow G11 5JR, UK
XX
DR   MD5; c3ac5c1643bdde87624883f4fb2d7daa.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1122
FT                   /organism="Human betaherpesvirus 5"
FT                   /host="Homo sapiens"
FT                   /strain="Merlin"
FT                   /mol_type="genomic DNA"
FT                   /country="United Kingdom:Cardiff"
FT                   /isolation_source="urine from a congenitally infected
FT                   child"
FT                   /collected_by="Gavin W.G. Wilkinson"
FT                   /collection_date="1999"
FT                   /db_xref="taxon:10359"
FT                   /culture_collection="ATCC:VR-1590"
FT   CDS             AY446894.2:117505..118626
FT                   /codon_start=1
FT                   /gene="UL80.5"
FT                   /locus_tag="HHV5wtgp075"
FT                   /product="capsid scaffold protein"
FT                   /note="clipped near C terminus; involved in capsid
FT                   morphogenesis"
FT                   /db_xref="GOA:Q6SW62"
FT                   /db_xref="InterPro:IPR001847"
FT                   /db_xref="InterPro:IPR035443"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q6SW62"
FT                   /protein_id="AAR31633.1"
FT                   /translation="MSHPLSAAVPAATAPPGATVAGASPAVSSLAWPHDGVYLPKDAFF
FT                   SLLGASRSAAPVMYPGAVAAPPSASPAPLPLPSYPASYGAPVVGYDQLAARHFADYVDP
FT                   HYPGWGRRYEPAPSLHPSYPVPPPPSPAYYRRRDSPGGMDEPPSGWERYDGGHRGQSQK
FT                   QHRHGGSGGHNKRRKETAAASSSSSDEDLSFPGEAEHGRARKRLKSHVNSDGGSGGHAG
FT                   SNQQQQQRYDELRDAIHELKRDLFAARQSSTLLSAALPSAASSSPTTTTVCTPTSELTS
FT                   GGGETPTALLSGGAKVAERAQAGVVNASCRLATASGSEAATAGPSTAGSSSCPASVVLA
FT                   AAAAQAAAASQSPPKDMVDLNRRIFVAALNKLE"
XX
SQ   Sequence 1122 BP; 187 A; 372 C; 339 G; 224 T; 0 other;
     atgtcgcacc ctctgagtgc tgcggttccc gccgctacgg ctcctccagg tgctaccgtg        60
     gcaggtgcgt cgccggctgt gtcgtctcta gcgtggcctc acgacggagt ttatttaccc       120
     aaagacgctt ttttctcgct acttggggcc agtcgctcgg cagcgcccgt catgtatccc       180
     ggcgccgtag cggcccctcc ttctgcttcg ccagcaccgc tgcctttgcc gtcttatccc       240
     gcgtcctacg gcgcccccgt cgtgggttac gaccagttgg cggcacgtca ctttgcggac       300
     tacgtggatc cccattatcc cgggtggggt cggcgttacg agcccgcgcc gtctttgcat       360
     ccgtcttatc ccgtgccgcc gccaccatca ccggcctatt accgtcggcg cgactctccg       420
     ggcggtatgg atgaaccacc gtccggatgg gagcgttacg acggtggtca ccgtggtcag       480
     tcgcagaagc agcaccgtca cgggggcagc ggcggacaca acaaacgccg taaggaaacc       540
     gcggcggcgt cgtcgtcgtc ctcggacgaa gacttgagtt tcccaggcga ggccgagcac       600
     ggccgggcac gaaagcgtct aaaaagtcac gtcaatagcg acggtggaag tggcgggcac       660
     gcgggttcca atcagcagca gcaacaacgt tacgatgaac tgcgggatgc cattcacgag       720
     ctgaaacgcg atctgtttgc cgcgcggcag agttctacgt tactttcggc ggctctcccc       780
     tctgcggcct cttcctcccc aactactact accgtgtgta ctcccaccag cgagctgacg       840
     agtggcggag gagaaacacc cacggcactt ctatccggag gtgccaaggt agctgagcgc       900
     gctcaggccg gcgtggtgaa cgccagttgc cgcctcgcta ccgcgtcggg ttctgaggcg       960
     gcaacggccg ggccctcgac ggcaggttct tcttcctgcc cggctagtgt cgtgttagcc      1020
     gccgctgctg cccaagccgc cgcagcttcc cagagcccgc ccaaagacat ggtagatctg      1080
     aatcggcgga tttttgtggc tgcgctcaat aagctcgagt aa                         1122
//