ID   AFM91192; SV 1; linear; genomic DNA; STD; HUM; 2556 BP.
XX
PA   JX178204.1
XX
DT   16-JUN-2013 (Rel. 117, Created)
DT   16-JUN-2013 (Rel. 117, Last updated, Version 1)
XX
DE   Homo sapiens (human) signal transducer and activator of transcription
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RX   DOI; 10.1016/j.ajhg.2012.06.015.
RX   PUBMED; 22883142.
RA   Mendez F.L., Watkins J.C., Hammer M.F.;
RT   "A haplotype at STAT2 Introgressed from neanderthals and serves as a
RT   candidate of positive selection in Papua New Guinea";
RL   Am. J. Hum. Genet. 91(2):265-274(2012).
XX
RN   [2]
RA   Mendez F.L., Hammer M.F.;
RT   ;
RL   Submitted (10-JUN-2012) to the INSDC.
RL   Arizona Research Laboratories, University of Arizona, 1041 E Lowell St,
RL   Tucson, AZ 85721, USA
XX
DR   MD5; 2cda8c423ebc914b8f1fb49768f30dff.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..2556
FT                   /organism="Homo sapiens"
FT                   /isolate="HGDP00454"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:9606"
FT   CDS             complement(join(JX178204.1:941..1083,JX178204.1:1377..1687,
FT                   JX178204.1:1956..2013,JX178204.1:2252..2434,
FT                   JX178204.1:2629..2765,JX178204.1:2879..2973,
FT                   JX178204.1:3102..3154,JX178204.1:3274..3409,
FT                   JX178204.1:3513..3611,JX178204.1:3776..3859,
FT                   JX178204.1:3939..3986,JX178204.1:4447..4540,
FT                   JX178204.1:4762..4782,JX178204.1:5179..5238,
FT                   JX178204.1:5448..5540,JX178204.1:5642..5800,
FT                   JX178204.1:6266..6414,JX178204.1:6578..6663,
FT                   JX178204.1:7076..7151,JX178204.1:7243..7332,
FT                   JX178204.1:7508..7603,JX178204.1:7932..8085,
FT                   JX178204.1:8241..8371))
FT                   /codon_start=1
FT                   /gene="STAT2"
FT                   /product="signal transducer and activator of transcription"
FT                   /db_xref="GOA:R9QE65"
FT                   /db_xref="InterPro:IPR000980"
FT                   /db_xref="InterPro:IPR001217"
FT                   /db_xref="InterPro:IPR008967"
FT                   /db_xref="InterPro:IPR012345"
FT                   /db_xref="InterPro:IPR013799"
FT                   /db_xref="InterPro:IPR013800"
FT                   /db_xref="InterPro:IPR013801"
FT                   /db_xref="InterPro:IPR015988"
FT                   /db_xref="InterPro:IPR022756"
FT                   /db_xref="InterPro:IPR035854"
FT                   /db_xref="InterPro:IPR036535"
FT                   /db_xref="InterPro:IPR036860"
FT                   /db_xref="UniProtKB/TrEMBL:R9QE65"
FT                   /protein_id="AFM91192.1"
FT                   /translation="MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQ
FT                   EAALGSDDSKATMLFFHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQL
FT                   AEMIFNLLLEEKRILIQAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSI
FT                   SQLKDQQDVFCFRYKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLG
FT                   RLTTLIELLLPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKG
FT                   LSCLVSYQDDPLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKF
FT                   TVRTRLLVRLQEGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWD
FT                   FGYLTLVEQRSGGSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISN
FT                   MNQLSIAWASVLWFNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQL
FT                   SMLRNKLFGQNCRTEDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGR
FT                   IMGFVSRSQERRLLKKTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEV
FT                   LQSLPLTEIIRHYQLLTEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHR
FT                   LIVVSNRQVDELQQPLELKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELES
FT                   VLESTLEPVIEPTLCMVSQTVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKI
FT                   EEIMPNGDPLLAGQNTVDEVYVSRPSHFYTDGPLMPSDF"
XX
SQ   Sequence 2556 BP; 661 A; 671 C; 670 G; 554 T; 0 other;
     atggcgcagt gggaaatgct gcagaatctt gacagcccct ttcaggatca gctgcaccag        60
     ctttactcgc acagcctcct gcctgtggac attcgacagt acttggctgt ctggattgaa       120
     gaccagaact ggcaggaagc tgcacttggg agtgatgatt ccaaggctac catgctattc       180
     ttccacttct tggatcagct gaactatgag tgtggccgtt gcagccagga cccagagtcc       240
     ttgttgctgc agcacaattt gcggaaattc tgccgggaca ttcagccctt ttcccaggat       300
     cctacccagt tggctgagat gatctttaac ctccttctgg aagaaaaaag aattttgatc       360
     caggctcaga gggcccaatt ggaacaagga gagccagttc tcgaaacacc tgtggagagc       420
     cagcaacatg agattgaatc ccggatcctg gatttaaggg ctatgatgga gaagctggta       480
     aaatccatca gccaactgaa agaccagcag gatgtcttct gcttccgata taagatccag       540
     gccaaaggga agacaccctc tctggacccc catcagacca aagagcagaa gattctgcag       600
     gaaactctca atgaactgga caaaaggaga aaggaggtgc tggatgcctc caaagcactg       660
     ctaggccgat taactaccct aatcgagcta ctgctgccaa agttggagga gtggaaggcc       720
     cagcagcaaa aagcctgcat cagagctccc attgaccacg ggttggaaca gctggagaca       780
     tggttcacag ctggagcaaa gctgttgttt cacctgaggc agctgctgaa ggagctgaag       840
     ggactgagtt gcctggttag ctatcaggat gaccctctga ccaaaggggt ggacctacgc       900
     aacgcccagg tcacagagtt gctacagcgt ctgctccaca gagcctttgt ggtagaaacc       960
     cagccctgca tgccccaaac tccccatcga cccctcatcc tcaagactgg cagcaagttc      1020
     accgtccgaa caaggctgct ggtgagactc caggaaggca atgagtcact gactgtggaa      1080
     gtctccattg acaggaatcc tcctcaatta caaggcttcc ggaagttcaa cattctgact      1140
     tcaaaccaga aaactttgac ccccgagaag gggcagagtc agggtttgat ttgggacttt      1200
     ggttacctga ctctggtgga gcaacgttca ggtggttcag gaaagggcag caataagggg      1260
     ccactaggtg tgacagagga actgcacatc atcagcttca cggtcaaata tacctaccag      1320
     ggtctgaagc aggagctgaa aacggacacc ctccctgtgg tgattatttc caacatgaac      1380
     cagctctcaa ttgcctgggc ttcagttctc tggttcaatt tgctcagccc aaaccttcag      1440
     aaccagcagt tcttctccaa cccccccaag gccccctgga gcttgctggg ccctgctctc      1500
     agttggcagt tctcctccta tgttggccga ggcctcaact cagaccagct gagcatgctg      1560
     agaaacaagc tgttcgggca gaactgtagg actgaggatc cattattgtc ctgggctgac      1620
     ttcactaagc gagagagccc tcctggcaag ttaccattct ggacatggct ggacaaaatt      1680
     ctggagttgg tacatgacca cctgaaggat ctctggaatg atggacgcat catgggcttt      1740
     gtgagtcgga gccaggagcg ccggctgctg aagaagacca tgtctggcac ctttctactg      1800
     cgcttcagtg aatcgtcaga agggggcatt acctgctcct gggtggagca ccaggatgat      1860
     gacaaggtgc tcatctactc tgtgcaaccg tacacgaagg aggtgctgca gtcactcccg      1920
     ctgactgaaa tcatccgcca ttaccagttg ctcactgagg agaatatacc tgaaaaccca      1980
     ctgcgcttcc tctatccccg aatcccccgg gatgaagctt ttgggtgcta ctaccaggag      2040
     aaagttaatc tccaggaacg gaggaaatac ctgaaacaca ggctcattgt ggtctctaat      2100
     agacaggtgg atgaactgca acaaccgctg gagcttaagc cagagccaga gctggagtca      2160
     ttagagctgg aactagggct ggtgccagag ccagagctca gcctggactt agagccactg      2220
     ctgaaggcag ggctggatct ggggccagag ctagagtctg tgctggagtc cactctggag      2280
     cctgtgatag agcccacact atgcatggta tcacaaacag tgccagagcc agaccaagga      2340
     cctgtatcac agccagtgcc agagccagat ttgccctgtg atctgagaca tttgaacact      2400
     gagccaatgg aaatcttcag aaactgtgta aagattgaag aaatcatgcc gaatggtgac      2460
     ccactgttgg ctggccagaa caccgtggat gaggtttacg tctcccgccc cagccacttc      2520
     tacactgatg gacccttgat gccttctgac ttctag                                2556
//