ID   AII80173; SV 1; linear; genomic DNA; STD; VRL; 2127 BP.
XX
PA   KM192302.1
XX
DT   13-AUG-2014 (Rel. 121, Created)
DT   13-AUG-2014 (Rel. 121, Last updated, Version 1)
XX
DE   Human betaherpesvirus 5 (Human cytomegalovirus) capsid maturation protease
XX
KW   .
XX
OS   Human betaherpesvirus 5 (Human cytomegalovirus)
OC   Viruses; Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
XX
RN   [1]
RA   Hsu J.-L., van Boomen D.J.H., Tomasec P., Weekes M.P., Antrobus R.,
RA   Stanton R.J., Ruckova E., Sugrue D., Wilkie G.S., Davison A.J.,
RA   Wilkinson G.W.G., Lehner P.J.;
RT   "Plasma membrane profiling defines an expanded class of cell surface
RT   proteins selectively targeted for degradation by HCMV US2 in cooperation
RT   with UL141";
RL   Unpublished.
XX
RN   [2]
RA   Davison A.J.;
RT   ;
RL   Submitted (14-JUL-2014) to the INSDC.
RL   MRC-University of Glasgow Centre for Virus Research, 8 Church Street,
RL   Glasgow G11 5JR, UK
XX
DR   MD5; 7e56c14ea434c347674af04823a9d3f2.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..2127
FT                   /organism="Human betaherpesvirus 5"
FT                   /host="Homo sapiens"
FT                   /strain="Merlin"
FT                   /isolate="RCMV1678"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:10359"
FT   CDS             KM192302.1:116450..118576
FT                   /codon_start=1
FT                   /gene="UL80"
FT                   /product="capsid maturation protease"
FT                   /EC_number="3.4.21.97"
FT                   /note="serine protease (N-terminal region); minor scaffold
FT                   protein (remainder of protein, clipped near C terminus);
FT                   involved in capsid morphogenesis"
FT                   /db_xref="GOA:F5HEA7"
FT                   /db_xref="InterPro:IPR001847"
FT                   /db_xref="InterPro:IPR035443"
FT                   /db_xref="UniProtKB/TrEMBL:F5HEA7"
FT                   /protein_id="AII80173.1"
FT                   /translation="MTMDEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHA
FT                   QGQGQPSLSVALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKS
FT                   ELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRCDDVEAATSLSGSETTPFKHVALCSV
FT                   GRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQRCGSTAVDASGDPFRSDSYGLL
FT                   GNSVDALYIRERLPKLRYDKQLVGVTERESYVKASVSPEAACVIKAASAERSGDSRSQA
FT                   ATPAAGARVPSSSPSPPVEPPSPVQPPALPASPSVLPAESPPSLSPSEPAEAASMSHPL
FT                   SAAVPAATAPPGATVAGASPAVSSLAWPHDGVYLPKDAFFSLLGASRSAAPVMYPGAVA
FT                   APPSASPAPLPLPSYPASYGAPVVGYDQLAARHFADYVDPHYPGWGRRYEPAPSLHPSY
FT                   PVPPPPSPAYYRRRDSPGGMDEPPSGWERYDGGHRGQSQKQHRHGGSGGHNKRRKETAA
FT                   ASSSSSDEDLSFPGEAEHGRARKRLKSHVNSDGGSGGHAGSNQQQQQRYDELRDAIHEL
FT                   KRDLFAARQSSTLLSAALPSAASSSPTTTTVCTPTSELTSGGGETPTALLSGGAKVAER
FT                   AQAGVVNASCRLATASGSEAATAGPSTAGSSSCPASVVLAAAAAQAAAASQSPPKDMVD
FT                   LNRRIFVAALNKLE"
XX
SQ   Sequence 2127 BP; 334 A; 707 C; 676 G; 410 T; 0 other;
     atgacgatgg acgagcagca gtcgcaggct gtggcgccgg tctacgtggg cggctttctc        60
     gcccgctacg accagtctcc ggacgaggcc gaattgctgt tgccgcggga cgtagtggag       120
     cactggttgc acgcgcaggg ccagggacag ccttcgttgt cggtcgcgct cccgctcaac       180
     atcaaccacg acgacacggc cgttgtagga cacgttgcgg cgatgcagag cgtccgcgac       240
     ggtctttttt gcctgggctg cgtcacttcg cccaggtttc tggagattgt acgccgcgct       300
     tcggaaaagt ccgagctggt ttcgcgcggg cccgtcagtc cgctgcagcc agacaaggtg       360
     gtggagtttc tcagcggcag ctacgccggc ctctcgctct ccagccggcg ctgcgacgac       420
     gtggaggccg cgacgtcgct ttcgggctcg gaaaccacgc cgttcaaaca cgtggctttg       480
     tgcagcgtgg gtcggcgtcg cggtacgttg gccgtgtacg ggcgcgatcc cgagtgggtc       540
     acacagcggt ttccagacct cacggcggcc gaccgtgacg ggctacgtgc acagtggcag       600
     cgctgcggca gcactgctgt cgacgcgtcg ggcgatccct ttcgctcaga cagctacggc       660
     ctgttgggca acagcgtgga cgcgctctac atccgtgagc gactgcccaa gctgcgctac       720
     gacaagcaac tagtcggcgt gacggagcgc gagtcgtacg tcaaggcgag cgtttcgcct       780
     gaggcggcgt gcgttattaa agcggcgtcc gccgagcgtt cgggcgacag ccgcagtcag       840
     gccgccacgc cggcggctgg ggcgcgcgtt ccctcttcgt ccccgtcgcc tccagtcgaa       900
     ccgccatctc ctgtacagcc gcctgcgctt ccagcgtcgc cgtccgttct tcccgcggaa       960
     tcaccgccgt cgctttctcc ctcggagccg gcagaggcgg cgtccatgtc gcaccctctg      1020
     agtgctgcgg ttcccgccgc tacggctcct ccaggtgcta ccgtggcagg tgcgtcgccg      1080
     gctgtgtcgt ctctagcgtg gcctcacgac ggagtttatt tacccaaaga cgcttttttc      1140
     tcgctacttg gggccagtcg ctcggcagcg cccgtcatgt atcccggcgc cgtagcggcc      1200
     cctccttctg cttcgccagc accgctgcct ttgccgtctt atcccgcgtc ctacggcgcc      1260
     cccgtcgtgg gttacgacca gttggcggca cgtcactttg cggactacgt ggatccccat      1320
     tatcccgggt ggggtcggcg ttacgagccc gcgccgtctt tgcatccgtc ttatcccgtg      1380
     ccgccgccac catcaccggc ctattaccgt cggcgcgact ctccgggcgg tatggatgaa      1440
     ccaccgtccg gatgggagcg ttacgacggt ggtcaccgtg gtcagtcgca gaagcagcac      1500
     cgtcacgggg gcagcggcgg acacaacaaa cgccgtaagg aaaccgcggc ggcgtcgtcg      1560
     tcgtcctcgg acgaagactt gagtttccca ggcgaggccg agcacggccg ggcacgaaag      1620
     cgtctaaaaa gtcacgtcaa tagcgacggt ggaagtggcg ggcacgcggg ttccaatcag      1680
     cagcagcaac aacgttacga tgaactgcgg gatgccattc acgagctgaa acgcgatctg      1740
     tttgccgcgc ggcagagttc tacgttactt tcggcggctc tcccctctgc ggcctcttcc      1800
     tccccaacta ctactaccgt gtgtactccc accagcgagc tgacgagtgg cggaggagaa      1860
     acacccacgg cacttctatc cggaggtgcc aaggtagctg agcgcgctca ggccggcgtg      1920
     gtgaacgcca gttgccgcct cgctaccgcg tcgggttctg aggcggcaac ggccgggccc      1980
     tcgacggcag gttcttcttc ctgcccggct agtgtcgtgt tagccgccgc tgctgcccaa      2040
     gccgccgcag cttcccagag cccgcccaaa gacatggtag atctgaatcg gcggattttt      2100
     gtggctgcgc tcaataagct cgagtaa                                          2127
//