ID DAA08429; SV 1; linear; genomic DNA; STD; FUN; 894 BP. XX PA BK006942.2 XX PR Project:PRJNA43747; XX DT 08-JUN-2010 (Rel. 105, Created) DT 29-JUN-2024 (Rel. 144, Last updated, Version 35) XX DE Saccharomyces cerevisiae S288C acylglycerone-phosphate reductase XX KW TPA; TPA:inferential. XX OS Saccharomyces cerevisiae S288C OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. XX RN [1] RX PUBMED; 8849441. RA Goffeau A., Barrell B.G., Bussey H., Davis R.W., Dujon B., Feldmann H., RA Galibert F., Hoheisel J.D., Jacq C., Johnston M., Louis E.J., Mewes H.W., RA Murakami Y., Philippsen P., Tettelin H., Oliver S.G.; RT "Life with 6000 genes"; RL Science 274(5287):. XX RN [2] RX PUBMED; 9169870. RA Churcher C., Bowman S., Badcock K., Bankier A., Brown D., Chillingworth T., RA Connor R., Devlin K., Gentles S., Hamlin N., Harris D., Horsnell T., RA Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C., Pearson D., RA Rajandream M., Rice P., Rowley N., Skelton J., Smith V., Barrell B. et al.; RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome IX"; RL Nature 387(6632 SUPPL):84-87(1997). XX RN [3] RX PUBMED; 34897464. RA Engel S.R., Wong E.D., Nash R.S., Aleksander S., Alexander M., Douglass E., RA Karra K., Miyasato S.R., Simison M., Skrzypek M.S., Weng S., Cherry J.M.; RT "New data and collaborations at the Saccharomyces Genome Database: updated RT reference genome, alleles, and the Alliance of Genome Resources"; RL Genetics 220(4):(2022). XX RN [4] RG Saccharomyces Genome Database RA ; RT ; RL Submitted (14-DEC-2009) to the INSDC. RL Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA XX RN [5] RC Sequence update by submitter RG Saccharomyces Genome Database RA ; RT ; RL Submitted (31-MAR-2011) to the INSDC. RL Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA XX RN [6] RC Protein update by submitter RG Saccharomyces Genome Database RA ; RT ; RL Submitted (04-MAY-2012) to the INSDC. RL Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA XX DR MD5; 8a39b675dc3b3db9b9f565b8ed04fc42. XX FH Key Location/Qualifiers FH FT source 1..894 FT /organism="Saccharomyces cerevisiae S288C" FT /chromosome="IX" FT /strain="S288C" FT /mol_type="genomic DNA" FT /db_xref="taxon:559292" FT CDS BK006942.2:126204..127097 FT /codon_start=1 FT /gene="AYR1" FT /gene_synonym="GBG1" FT /locus_tag="YIL124W" FT /product="acylglycerone-phosphate reductase" FT /EC_number="1.1.1.101" FT /EC_number="3.1.1.3" FT /note="Bifunctional triacylglycerol lipase and 1-acyl DHAP FT reductase; NADPH-dependent 1-acyl dihydroxyacetone FT phosphate reductase involved in phosphatidic acid FT biosynthesis; lipid droplet triacylglycerol lipase involved FT in mobilization of non-polar lipids; found in lipid FT particles, endoplasmic reticulum and mitochondrial outer FT membrane; forms NADPH-regulated channel in mitochondrial FT outer membrane; required for spore germination; role in FT cell wall biosynthesis; capable of metabolizing steroid FT hormones" FT /experiment="EXISTENCE:direct assay:GO:0004806 triglyceride FT lipase activity [PMID:24187129]" FT /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm FT [PMID:11914276]" FT /experiment="EXISTENCE:direct assay:GO:0005741 FT mitochondrial outer membrane [PMID:16407407]" FT /experiment="EXISTENCE:direct assay:GO:0005811 lipid FT droplet [PMID:10617610|PMID:24868093]" FT /experiment="EXISTENCE:genetic interaction:GO:0004806 FT triglyceride lipase activity [PMID:24187129]" FT /experiment="EXISTENCE:genetic interaction:GO:0019433 FT triglyceride catabolic process [PMID:24187129]" FT /experiment="EXISTENCE:mutant phenotype:GO:0000140 FT acylglycerone-phosphate reductase activity [PMID:10617610]" FT /experiment="EXISTENCE:mutant phenotype:GO:0004806 FT triglyceride lipase activity [PMID:24187129]" FT /experiment="EXISTENCE:mutant phenotype:GO:0006654 FT phosphatidic acid biosynthetic process [PMID:10617610]" FT /experiment="EXISTENCE:direct assay:GO:0005739 FT mitochondrion [PMID:16823961|PMID:24769239|PMID:14576278]" FT /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic FT reticulum [PMID:26928762|PMID:10617610]" FT /protein_id="DAA08429.1" FT /translation="MSELQSQPKKIAVVTGASGGIGYEVTKELARNGYLVYACARRLEP FT MAQLAIQFGNDSIKPYKLDISKPEEIVTFSGFLRANLPDGKLDLLYNNAGQSCTFPALD FT ATDAAVEQCFKVNVFGHINMCRELSEFLIKAKGTIVFTGSLAGVVSFPFGSIYSASKAA FT IHQYARGLHLEMKPFNVRVINAITGGVATDIADKRPLPETSIYNFPEGREAFNSRKTMA FT KDNKPMPADAYAKQLVKDILSTSDPVDVYRGTFANIMRFVMIFVPYWLLEKGLSKKFKL FT DKVNNALKSKQKNKDD" XX SQ Sequence 894 BP; 271 A; 165 C; 199 G; 259 T; 0 other; atgtcggagt tacagtcaca acctaaaaag attgccgttg ttacaggcgc ctcaggtggt 60 attggatatg aggtaacgaa ggaattagcc agaaatggct atttggttta tgcatgtgca 120 agaagactag aaccaatggc acaattggcc atccaatttg gtaacgatag tatcaaacca 180 tataagttgg atatttccaa gccagaagaa attgtaacat tttctggttt tttgcgagct 240 aatttacctg atggtaaatt agatttattg tacaacaatg ccggtcagag ttgtacattc 300 cctgcattgg atgcaacaga tgctgcagta gaacaatgct ttaaggtcaa tgtgtttggt 360 catatcaaca tgtgccgtga attgtcggag ttccttatta aagcgaaagg aaccattgtc 420 ttcactggtt ccttggcagg agttgtgtca ttcccctttg gtagcattta ttccgcttct 480 aaagctgcta tccaccaata tgctcgtggg ttacatctag agatgaagcc cttcaacgtg 540 agagtgatta acgctattac tggcggtgtg gctactgata tcgctgataa aaggcccttg 600 cctgaaacct caatatacaa cttccctgaa ggtagggaag cttttaattc aagaaaaacc 660 atggctaagg acaataagcc catgccagct gatgcgtacg caaagcaact ggttaaagat 720 atcttgagca ctagtgaccc tgtagatgtt tatagaggaa cgttcgccaa catcatgcgt 780 tttgtcatga tatttgttcc ttactggcta ttggaaaaag gactttccaa aaaatttaaa 840 ttggacaaag ttaataatgc tttgaagtcg aaacagaaga ataaggacga ttag 894 //