ID   POB49698; SV 1; linear; genomic DNA; WGS; PRO; 15621 BP.
XX
PA   PDGH01000027.1
XX
PR   Project:PRJNA413285;
XX
DT   09-MAR-2018 (Rel. 136, Created)
DT   09-MAR-2018 (Rel. 136, Last updated, Version 1)
XX
DE   Vibrio vulnificus RTX toxin
XX
KW   WGS.
XX
OS   Vibrio vulnificus
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
XX
RN   [1]
RC   Publication Status: Online-Only
RX   PUBMED; 29358930.
RA   Roig F.J., Gonzalez-Candelas F., Sanjuan E., Fouz B., Feil E.J.,
RA   Llorens C., Baker-Austin C., Oliver J.D., Danin-Poleg Y., Gibas C.J.,
RA   Kashi Y., Gulig P.A., Morrison S.S., Amaro C.;
RT   "Phylogeny of Vibrio vulnificus from the Analysis of the Core-Genome:
RT   Implications for Intra-Species Taxonomy";
RL   Front Microbiol. 8:2613-2613(2018).
XX
RN   [2]
RA   Roig F.J.;
RT   ;
RL   Submitted (06-OCT-2017) to the INSDC.
RL   Microbiology and Ecology, University of Valencia, Dr. moliner, 50,
RL   Burjassot, Valencia 46100, Spain
XX
DR   MD5; 034844f138cf48c0276e8c6ef2a2fc54.
DR   BioSample; SAMN07739079.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..15621
FT                   /organism="Vibrio vulnificus"
FT                   /strain="CECT4608"
FT                   /mol_type="genomic DNA"
FT                   /country="Spain"
FT                   /isolation_source="Eel tank water"
FT                   /collection_date="1990"
FT                   /note="biotype: 1"
FT                   /db_xref="taxon:672"
FT   CDS             PDGH01000027.1:87649..103269
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /locus_tag="CRN52_02910"
FT                   /product="RTX toxin"
FT                   /note="Derived by automated computational analysis using
FT                   gene prediction method: Protein Homology."
FT                   /db_xref="InterPro:IPR008979"
FT                   /db_xref="InterPro:IPR011049"
FT                   /db_xref="InterPro:IPR011509"
FT                   /db_xref="InterPro:IPR020972"
FT                   /db_xref="InterPro:IPR020974"
FT                   /db_xref="InterPro:IPR022742"
FT                   /db_xref="InterPro:IPR029058"
FT                   /db_xref="InterPro:IPR038383"
FT                   /db_xref="PDB:2N9W"
FT                   /db_xref="UniProtKB/TrEMBL:A0A2S3R7M0"
FT                   /inference="COORDINATES:similar to AA
FT                   sequence:RefSeq:WP_011081430.1"
FT                   /protein_id="POB49698.1"
FT                   /translation="MGKPFWRSVEYFFTGNYSADDGNNSIVAIGFGGEIHAYGGDDHVT
FT                   VGSIGATVYTGSGNDTVVGGSAYLRVEDTTGHLSVKGAAGYADINKSGDGNVSFAGAAG
FT                   GVSIDHLGNNGDVSYGGAAAYNGITRKGLSGNVTFKGAGGYNALWHETNQGNLSFAGAG
FT                   AGNKLDRTWFNRYQGSRGDVTFDGAGAANSISSRVETGNITFRGAGADNHLVRKGKVGD
FT                   ITLQGAGASNRIERTRQAEDVYAQTRGNIRFEGVGGYNSLYSDVAHGDIHFSGGGAYNT
FT                   ITRKGSGSSFDAQGMEYAKAEDIVLTAAQMHGLSIDNGNKFHAVTAVKSEREPNTYLFA
FT                   IADGTYTKINKVRLYNDPETGKLKYYSEAWFKRGNHLAELARSDVSSAGGFEVNPINGG
FT                   YTLANIAVEHQQSVTVHAVEKNLTEYEWVTYANGTLIDAKDVALSEAKMGGHAISTDGT
FT                   TVDVQAVKSNRKPNTYVYAKVLGPYTKIVVVELANDPKTGALKYQARSWYKEGDHTANL
FT                   ANEDISSANGYHSMGKGGYSLSDLHYSVNAVRSTSETVADIDEYTDQTLFKPATDSGES
FT                   SGDVRFNGAGGGNVIKSNVTRGNVYFNGGGIANVILHSSQFGNTEFNGGGAANVIVKSG
FT                   EEGDLTFRGAGLANVLVHQSKQGKMDVYAGGAVNVLVRIGDGQYLAHLLAYGNISVHKG
FT                   NGNSRVVMLGGYNTHTQIGSGNGLWLAAGGFNVMTQVGKGDVASVLAGGANVLTKVGDG
FT                   DLTAGMLGGANVITHISGDNETSNTTAVALGGANILTKKGKGNTLAVMGGGANVLTHVG
FT                   DGTTTGVMVGGANILTKVGNGDTTGIMLGVGNVLTHVGDGQTLGVMGAAGNIFTKVGDG
FT                   TSIAVMIGAGNIFTHVGEGNAWALMGGLGNVFTKVGNGDALALMVAEANVFTHIGDGMS
FT                   VALMLAKGNVATKVGNGTTLAAMVGNANIFTHVGSGSTFAAMIGQANIMTKVGNDLTAA
FT                   LMVGKANIYTHVGDGTSLGIFAGEVNVMTKIGNGTTLAAMFGKANIMTHVGDGLTGVLA
FT                   LGEANIVTKVGDDFMGVVAAAKANVVTHVGDATTAAVLAGKGNILTKVGEGTTVGLLIS
FT                   DIGNVMTHVGDGTTIGIAKGKANIITKVGDGLGVNVAWGQANVFTQVGDGDRYNFAKGE
FT                   ANIITKVGDGKEVSVVQGKANIITHVGNGDDYTGAWGKANVITKVGNGRNVVLAKGEAN
FT                   IVTQVGDGDSFNALWSKGNIVTKVGDGMQVTAAKGKANITTTVGDGLSVTAAYGDANIN
FT                   TKVGDGVSVNVAWGKYNINTKVGDGLNVAVMKGKANANIHVGDGLNINASYAQNNVAIK
FT                   VGNGDFYSLAVASSNTSSNKLSALFDNIKQTLLGVGGSQAINYLVQGDEASSSGTQKGR
FT                   GAIATPEITKLDGFQMEAIEEVGSDLGDSLTGSVTKVDTPDLNKMQNALDVDGSSDQTQ
FT                   APNLIVNGDFEQGDRGWKSTHGVEASYSGNVYGVNGEGHGARVTELDTYTNTSLYQDLT
FT                   DLTEGEVIAVSFDFAKRAGLSNNEGIEVLWNGEVVFSSSGDASAWQQKTLKLTAHAGSN
FT                   RIEFKGTGHNDGLGYILDNVVAKSESSQQANAVSEHATQNQASQNALSDKERAEADRQR
FT                   LEQEKQKQLDAVAGSQSQLESTDQQALGNNGQAQRDAVKEESEAVTAELTKLAQGLDVL
FT                   DGQATHTGESGDQWRNDFAGGLLDGVQSQLDDAKQLANDKIAAAKQTQSDNNSKVKESV
FT                   AKSEAGVAQGEQNRAGAEQDIAEAKADAETRKADAVAKSNDAKQAESDAHSAANDAQSR
FT                   GDRDAMNAENKANQAQNDAKGTKQNEGDRPDREGVAGSGLSGNAHSVEGAGETGSHITT
FT                   DSQTNADGRFSEGLSEQEQEALEGATNAVNRLQINAGIRGKNSGSTITSMFTETNSDSI
FT                   VVPTTASQDVVRKEIRISGVNLEGLGEASHDSAESLVAARAEKVANLYRWLDTDNDVAT
FT                   DKYVPVPGFERVDVDVSDEVKQRMIQSMSGYIEHTDNQVPKDQAEALATLFVESTLDYD
FT                   WDKRVEFLTKLESYGYSFEAPHAEKSIVSFWSGKNFKQYRDILDNAQTDGKKVVYDIDV
FT                   KGNAFAIDLNKHLMRWGGLFLDPDNAEQNQLKSSIDAATFSNTGFWSSVYATGAQNDVY
FT                   VIAEGGVRLGNYFWNVELPALRQLQREGLVGEIRLLDKPVSEYKDLPADQIGRRLTDAG
FT                   VAVKVRFDALSHERQAELLADNPDGYKADTLVELDVKLSAIDSMLRESLPFYSLRTERN
FT                   LLVQEGEEGFEVRSWPGIDGKSKTILLDNPEDAAQQKSIERFILANFDNFEQMPDELFL
FT                   VDNKVLSHHDGRTRIIAQKEDGAWTYNTNVELMSVTELLDAAHVNGKVRGDSYQQVIDA
FT                   LTEYHASTVEHADYELESVEKLLNLRKQIEGYVLGHPDSGRVEAMNSLLNQVNSRLEEV
FT                   SVLAVSEQSIKAHDSFSRLYDQLDNANLKESKHLYLDGNGDFVTKGKGNLATIDQLGGS
FT                   DAVLEKVKAAVTHEYGQVVADTIFARLSANDLAKDGKGIDIAGLNKVHQAIEQHMSPVS
FT                   ATMYIWKPSDHSTLGHAALQIGQGRTQLEGQAAADFNKQNYVSWWPLGSKSSNIRNIFN
FT                   VATEDQPDLKLRWSDFSQPAHQNDTLEHDMASEENDGFGLKDGETKLKRFIEKLNAAKG
FT                   IDASYKDASEGYASVLLGNPDMLASTGIPAHVFQPFVDQWNDTSYDMMDVANRFAEELQ
FT                   KQAQASGDPALVEKRIDNVVRLFAERALEEIEAFKASQADEGRVFRINLEGLDVAAMQA
FT                   EWNRLSNDPDARYQLLTKNCSSTVAKVLKAGGADKLIGHTWRPKFGVWTPTELFNFGQA
FT                   LQEAQLEIAAKKQSHQVTDVLDALSGNEKHKENVTIENDGTPPRDKESLSPLTRFLNNE
FT                   LYGEKDARRKIGEITQTLLDHAVENGESQKVTLKGEAGRLTGYYHQGAASSEGETSATS
FT                   GKVVLFLHGSGSSAEEQASAIRNHYQKQGIDMLAVNLRGYGESDGGPSEKGLYQDARTM
FT                   FNYLVNDKGIDPSNIIIHGYSMGGPIAADLARYAAQNGQAVSGLLLDRPMPSMTKAITA
FT                   HEMANPAGIVGAIAKAVNGQFSVEKNLKGLPKETPILLLTDNEGLGEEGEKLRAKLAIA
FT                   GYNVTGEQTFYGHEASNRLMGQYADQIVSGLFNAEQAAVEAGEVLKGLEKDFKRYGDAL
FT                   KPDTSVPGKSKDIRTTKDFLNGYKNDHAKEIVDGFRSDMSIKQLVDLFVKGNWSAEQKG
FT                   ALAWEIESRALKVTFQNKSEKYNRLFREIASAGVVDAKATEQLAPQLMLLNLSNDGFGG
FT                   RCDPLSKLVLVAKQLENDGQVGVARQLLEKMYSAAAVLSNPTLYSDSEKANASKLLSSL
FT                   AAIHAKNPMHDTSMKVWQEKLEGKQALTVNGVVEKITDASANGKPVLLELDAPGHAMAA
FT                   WAKDSGDDRVYGFYDPNAGIVEFSSAEKFGDYLTRFFGKSDLDMAQSYKLGKNDAGEAI
FT                   FNRVVVMDGNTLASYKPTFGDKTTMQGILDLPVFDATPIKKPTGGVASDLEALGDKTKV
FT                   VVDLAQIFTVQELKERAKVFAKPIGASYQGILDQLDLVHQAKGRDQIAASFELNKKIND
FT                   YIAEHPTSGRNQALTQLKEQVTSALFIGKMQVAQAGIDAIAQTRPELAARIFMVAIEEA
FT                   NGKHVGLTDMMVRWANEDPYLAPKHGYKGETPSDLGFDAKYHVDLGEHYADFKQWLETS
FT                   QSNGLLSKATLDESTKTVHLGYSYQELQDLTGAESVQMAFYFLKEAAKKADPISGDSAE
FT                   MILLKKFADQSYLSQLDSDRMDQIEGIYRSSHETDIDAWDRRYSGTGYDELTNKLASAT
FT                   GVDEQLAVLLDDRKGLLIGEVHGSDVNGLRFVNEQMDALKKQGVTVIGLEHLRSDLAQP
FT                   LIDRYLATGVMSSELSAMLKTKHLDVTLFENARANGIRIVALDANSSARPNVQGTEHGL
FT                   MYRAGAANNIAVEVLQNLPDGEKFVAIYGKAHLQSHKGIEGFVPGITHRLDLPALKVSD
FT                   SNQFTVEQDDVSLRVVYDDVANKPKITFKDSLSGANTALHNQNVNDWERVVVTPTADGG
FT                   ESRFDGQIIVQMENDDVVAKAAANLAGKHPESSVVVQIDSDGNYRVVYGDPSKLDGKLR
FT                   WQLVGHGRDDSESNNTRLSGYSADELAVKLAKFQQSFNQAENINNKPDHISIVGCSLVS
FT                   DDKQKGFGHQFINAMDANGLRVDVSVRSSELAVDEAGRKHTKDANGDWVQKAENNKVSL
FT                   SWDEQGEVVAKDERIRNGIAEGDIDLSRIGVSDVDEPARGAIGDNNDVFDAPEKRKAET
FT                   ETSSSSANNKLSYSGNIQVNVGDGEFTAVNWGTSNVGIKVGTGGFKSLAFGDNNVMVHI
FT                   GNGESKHSFDIGGYQALEGAQMFIGNRNVSFNLGRSNDLIVMMDKSIPTPPLVNPFDGA
FT                   ARISGVLQSIATSGEGQDWLAAQEQQWTLSGAKKFVKDMSGLDQSSSVDYTSLVELDSQ
FT                   NERSSRGLKHDAEAALNKQYNQWLSGNSDSDTSKLSRADKLRQANEKLAFNFAVGGQGA
FT                   DIQVTTGNWNFMFGDNIQSILDTNLGSLFGLMTQQFSATGQAKTTFTYTPEDLPRQLKN
FT                   KLLGQLAGVGAETTLADIFGVDYTASGQIVSRNGEAVDGVAILKEMLEVIGEFSGDQLQ
FT                   AFVDPAKLLDSLKSGINMGADGIKSFAETHGLKEKAPEEEEDNSSVSVNGASVNSAQGA
FT                   TVADGSTETAETPDRAFGFNSLNLPNLFATIFSQDKQKEMKSLVENLKENLTADLLNMK
FT                   EKTFDFLRNSGHLQGDGDINISLGNYNFNWGGDGKDLGAYLGDNNNFWGGRGDDVFYAT
FT                   GTSNIFTGGEGNDMGVLMGRENMMFGGDGNDTAVVAGRINHVFLGAGDDQSFVFGEGGE
FT                   IDTGSGRDYVVTSGNFNRVDTGDDQDYSVTIGNNNQVELGAGNDFANVFGNYNRINASA
FT                   GNDVVKLMGYHAVLNGGEGEDHLIAAAISKFSQFNGGEGRDLMVLGGYQNTFKGGTDVD
FT                   SFVVSGDVIDNLVEDIRSEDNIVFNGIDWQKLWFERSGYDLKLSILRDPASDSDQAKFE
FT                   HIGSVTFSDYFNGNRAQVIIAMGEKDATGEREYTTLSESAIDALVQAMSGFDPQAGDNG
FT                   FMDNLDSKSRVAITTAWADVVHKKGITV"
XX
SQ   Sequence 15621 BP; 4318 A; 3457 C; 4305 G; 3541 T; 0 other;
     atgggaaaac cattttggag aagtgttgaa tacttcttca cagggaacta ttccgccgac        60
     gatggaaaca acagtattgt tgctatcggt tttggtggag aaatccatgc ctacggtggt       120
     gatgatcatg tcactgtcgg atcgattggt gcaacggttt ataccggcag cggcaatgat       180
     acggtcgtag gcggttcggc atatctaaga gtggaagaca ccactgggca cctttctgta       240
     aaaggcgcag ctgggtatgc agacattaat aaaagtggcg atggcaatgt gtcattcgct       300
     ggtgccgctg gcggtgtgtc gattgaccac ttaggtaata atggtgatgt cagttacggc       360
     ggtgccgcgg cttataatgg cattacccgc aaaggtttga gcggcaacgt cacctttaaa       420
     ggcgctggcg gttacaatgc cctttggcat gaaaccaacc aaggtaatct ctcttttgct       480
     ggcgcaggag cgggcaataa actagaccgt acttggttca accgttatca aggctcgcgt       540
     ggtgatgtga cgtttgatgg cgctggcgcg gcaaacagca ttagttcacg tgttgaaacc       600
     ggcaacatta ctttccgtgg ggctggtgct gacaaccatt tggtccgtaa aggcaaagtg       660
     ggcgatatta ccttgcaagg tgcgggcgca tcaaaccgta ttgagcgtac acgccaagcg       720
     gaagatgttt acgcgcaaac acgcggtaac attcgctttg aaggtgtcgg cggttacaac       780
     agcctttact ccgatgtggc acacggtgac atccatttct ccggtggcgg tgcttataac       840
     accattacac gaaaaggcag tggtagtagc ttcgatgctc aaggtatgga atacgcgaaa       900
     gcggaagaca ttgttctcac cgcggcgcag atgcatggtt tatcgattga taacggcaac       960
     aagttccatg cggttaccgc tgtaaagtca gagcgggagc caaatactta tctgtttgct      1020
     atcgcagatg gtacttacac caaaatcaac aaagttcgtc tctataacga tccagaaacg      1080
     ggcaaactca aatactactc tgaggcttgg tttaagcgcg gcaatcattt agctgagctt      1140
     gctcgttccg atgtctcttc tgctggtggt tttgaagtta atccaatcaa tggtggttac      1200
     acccttgcta atattgccgt tgagcatcag caatcagtga cggttcatgc cgttgaaaaa      1260
     aatctgactg aatatgagtg ggtgacctac gccaatggca cactgattga tgcgaaagat      1320
     gtggcattgt cagaggcgaa aatgggcggt cacgccatct cgaccgatgg gacgacagtc      1380
     gatgttcaag cggtgaaatc aaaccgtaaa ccaaacactt atgtttacgc aaaagtgctt      1440
     gggccttaca caaaaattgt ggtggttgaa cttgctaatg atcccaaaac aggggcgctt      1500
     aagtatcaag ctcgctcttg gtacaaagag ggtgatcata ccgcaaacct agccaatgaa      1560
     gatatttcgt ctgcaaacgg atatcactcg atgggcaaag gcggctactc actcagcgat      1620
     ctgcattaca gtgtgaacgc ggtaagaagt accagcgaaa ccgtggccga catcgacgag      1680
     tacaccgatc aaaccttgtt taagccagcg accgatagcg gtgaaagctc tggtgatgtg      1740
     cgcttcaatg gtgcgggtgg cggtaacgtc atcaagtcca atgtgactcg cggcaatgtc      1800
     tactttaatg gtggcggtat cgctaacgtc atcctccaca gttcgcaatt tggtaatacc      1860
     gagttcaacg gtggtggcgc ggcaaacgtg attgtcaaaa gtggcgaaga aggggatctc      1920
     accttccgcg gcgcgggttt ggcgaacgtg ttggtacacc aaagcaagca aggcaagatg      1980
     gatgtttacg cgggcggtgc ggtaaacgta ctggttcgta ttggcgatgg tcaatacctt      2040
     gcgcatttgc tggcttacgg caacatttcc gtgcacaaag gcaatggcaa cagccgtgtc      2100
     gttatgctcg gtggttacaa cacccatacc caaattggct ccggcaacgg cttgtggttg      2160
     gcggcgggcg gcttcaacgt gatgacgcaa gtgggtaaag gtgatgtagc atcggtactg      2220
     gctggcggcg cgaacgtgct caccaaagtg ggtgacggcg atctaaccgc aggtatgttg      2280
     ggcggcgcaa acgtgattac ccacatcagc ggcgacaatg aaacctcgaa taccacagcc      2340
     gtagccttag gcggtgccaa cattctcacc aaaaaaggca aagggaatac ccttgcggtg      2400
     atgggcggtg gcgcaaacgt gctgacgcat gtgggtgatg gtacaacaac tggcgtaatg      2460
     gtcggtggag cgaacattct caccaaagta ggtaacggcg acacgaccgg cataatgctt      2520
     ggtgttggca acgtgctaac gcatgttggt gatggccaaa ctcttggtgt gatgggcgca      2580
     gcgggtaaca tcttcaccaa agtcggtgat ggaacctcta ttgcggtcat gattggtgct      2640
     ggcaacatct tcacccatgt gggagaaggg aatgcttggg cgctgatggg cggcttgggt      2700
     aacgtcttta ccaaagtcgg caacggtgat gcgctagcct taatggtggc agaagccaac      2760
     gtcttcactc acattggtga tggtatgtcg gtcgcactga tgttagccaa aggcaacgtt      2820
     gcgacaaaag tgggtaatgg aaccacactc gctgcaatgg ttggtaacgc caatatcttc      2880
     actcacgtag gcagtggcag tacgtttgct gcaatgatcg gccaagccaa catcatgacc      2940
     aaagtgggca atgatctcac cgcggcactg atggtcggta aagcaaatat ctacacacat      3000
     gtcggtgatg gaaccagcct aggaatattc gcgggcgaag tgaacgtgat gactaagatc      3060
     ggtaacggca caaccttggc ggcgatgttc ggtaaagcca acatcatgac gcatgtcggc      3120
     gatggtctaa cgggcgtgtt agcactgggc gaagccaata ttgtcaccaa agtgggtgat      3180
     gatttcatgg gggttgtggc ggcagcaaaa gccaacgtcg tgactcatgt tggtgatgca      3240
     acaaccgcgg ctgtgttggc tggtaaaggc aatatcctaa ccaaagtggg tgaaggcacc      3300
     acggtagggt tgttgatttc cgatatcggc aacgtaatga cccacgtcgg agatggcacg      3360
     accattggta ttgccaaagg caaggcaaac atcattacca aagtcggtga tggtttgggc      3420
     gtcaatgtcg cttgggggca agcaaacgtg tttacccaag tgggcgacgg tgatcgctat      3480
     aactttgcca aaggtgaagc caacatcatc actaaagtgg gtgatggcaa agaagtctcc      3540
     gtggtgcaag gtaaagccaa catcattact catgtgggca atggcgacga ctacaccgga      3600
     gcttggggta aagcgaacgt cattactaaa gtgggtaatg gccgtaacgt ggtactggca      3660
     aaaggtgaag ccaatattgt gacccaagta ggtgatggcg acagctttaa cgcactttgg      3720
     agcaaaggca acattgtcac caaagtgggt gatggtatgc aggtgacggc agcaaaaggc      3780
     aaagccaaca tcaccaccac cgttggtgat ggcttgagtg tgacagccgc ctatggtgac      3840
     gccaacatca ataccaaagt cggtgatggt gtatccgtca acgtcgcttg gggcaaatat      3900
     aacatcaaca cgaaagtggg tgatggcctg aatgttgccg tgatgaaagg caaagctaac      3960
     gccaatattc acgtgggcga tggcctcaac atcaatgcct cttacgcaca aaacaacgtt      4020
     gcaatcaaag ttggtaacgg cgatttttac agtttggcag ttgcgtcaag caacaccagc      4080
     agcaacaagc tctcggcact gtttgataac attaaacaaa ccctacttgg tgtgggtggt      4140
     agccaagcaa tcaactactt ggttcaaggt gatgaagcat cgtcatccgg tacgcaaaaa      4200
     ggccgtggtg cgattgcaac accggaaatc accaagctgg atggtttcca aatggaagcc      4260
     attgaagaag tgggctcgga cttgggcgat agtctaaccg gcagtgtcac caaggtagat      4320
     accccagatc tcaacaagat gcaaaatgca ctcgacgttg acggatcttc tgatcaaact      4380
     caagctccga atctcattgt gaatggtgat tttgagcaag gtgatcgtgg ttggaaatcg      4440
     acacacggtg ttgaagcttc ctattcgggc aatgtctatg gcgtgaacgg cgaaggtcac      4500
     ggcgcacgtg tgacggaact ggatacctac accaacacca gtctctatca agatctgacc      4560
     gatcttacgg aaggtgaagt cattgctgtg agctttgatt ttgcgaaacg tgcaggtcta      4620
     tcgaataacg aaggcattga agttctttgg aatggcgaag tcgtcttctc atcgtctggt      4680
     gatgcctctg cttggcagca aaaaacctta aaactgaccg cgcatgctgg cagtaaccga      4740
     atcgaattca aaggcacagg ccacaatgat ggactgggct atatcctaga taatgtcgtg      4800
     gcgaaatcgg aatcgtcgca acaagccaac gcagtgagtg agcacgcgac acaaaatcaa      4860
     gcgtcgcaga atgccctatc agataaagag cgcgcagaag cggatcgcca acgtcttgaa      4920
     caagaaaagc agaaacagct tgatgctgtc gcagggtcac aaagtcagtt ggagtcgacc      4980
     gaccaacaag cgctaggaaa taacggtcaa gctcaacgtg atgcggtgaa agaagagtcg      5040
     gaagccgtga ccgccgagtt gacaaaactg gcgcaaggtc tcgatgtgct tgatggccaa      5100
     gcaacgcata ctggcgagtc aggcgaccaa tggcgcaatg attttgccgg tggtctgctc      5160
     gatggcgttc aaagccagct cgacgatgcc aagcaactcg cgaatgacaa gattgctgca      5220
     gcgaagcaga cgcagtctga caataacagc aaagtcaaag aatccgttgc gaaatctgaa      5280
     gcgggtgtgg cacaaggtga gcaaaatcgc gcaggtgcag agcaagacat tgccgaagct      5340
     aaagccgatg cagaaacacg caaagccgat gctgtggcga agagtaacga tgcgaaacag      5400
     gccgaatctg acgcacacag cgccgcaaac gacgcgcaat cgcgtggtga tcgcgatgcg      5460
     atgaatgccg aaaacaaagc caaccaagcg cagaatgatg ccaaagggac caagcaaaac      5520
     gaaggcgatc gccctgaccg tgaaggcgtg gctggcagcg gtctttcagg caacgctcat      5580
     agcgtggaag gtgctggcga aacgggcagt catatcacca ctgacagcca aacaaacgcc      5640
     gatggtcgat tcagtgaagg tctgagcgaa caagagcaag aagcgctgga aggtgcgaca      5700
     aacgcagtga accgtctgca aattaacgca ggtattcgcg gaaagaacag cggtagcaca      5760
     atcacctcaa tgttcaccga aacaaactcc gacagcattg tggtaccaac cactgcgtct      5820
     caggatgtgg ttcgaaaaga gattcgcatt tctggggtga atttagaggg gcttggtgaa      5880
     gcttcgcatg actctgctga atcgcttgtg gctgctcgcg cggaaaaagt ggcgaatctc      5940
     tatcgctggc tagacactga taatgacgtg gcgacggaca agtatgtacc tgtccctggc      6000
     tttgaacgcg tcgatgttga tgtctctgat gaagtcaagc agcgcatgat tcaatctatg      6060
     agcggttaca tcgaacacac cgacaatcaa gtaccgaaag atcaagcgga agcattagcc      6120
     actttgtttg ttgaatcgac gctcgattat gactgggaca aacgcgttga gtttctcact      6180
     aagcttgaga gctatggtta tagttttgaa gcgccacacg cagagaaaag cattgtttcc      6240
     ttctggtctg gtaaaaactt caagcaatac cgagacattc tcgacaatgc ccagactgat      6300
     ggcaaaaagg tcgtgtacga catcgatgtt aaaggcaacg catttgcaat cgacctgaat      6360
     aagcatttaa tgcgttgggg cggcctgttc cttgacccag ataacgccga gcaaaatcag      6420
     ttgaaatcat caatcgatgc agcaacgttc agcaatacag gtttttggag ttcggtctat      6480
     gcgacggggg cacaaaatga tgtgtatgtc atcgcagaag gtggtgtgcg tcttggcaac      6540
     tatttctgga atgttgagct acctgcatta cgccaattgc agcgtgaagg gttagtcggt      6600
     gaaattcgac tgcttgataa gccagtatcc gagtacaaag atctaccagc agaccagatt      6660
     ggacgccgac ttaccgatgc aggtgttgcc gttaaagtac gctttgatgc gttgagtcac      6720
     gagagacaag ctgagctttt ggccgacaat ccagatggtt acaaagccga tacgctggtt      6780
     gagttggatg tgaagctaag tgcgatcgat agcatgttgc gtgaatctct accattctat      6840
     tcacttcgta ctgagcgcaa cctcttagtg caagaaggcg aagaaggatt tgaagttcgc      6900
     tcatggccgg gaatcgatgg aaagagcaag actattctgc ttgataaccc agaagatgca      6960
     gctcaacaaa aatccattga gcgctttatc ttggcaaact tcgacaactt cgagcagatg      7020
     ccagatgaac ttttcttagt ggataacaag gtgctctcgc atcacgatgg ccgcacgcga      7080
     attatagcgc aaaaagaaga cggtgcttgg acgtacaaca ccaatgttga actgatgtct      7140
     gtcactgagc tactcgatgc tgctcatgtg aacggtaaag ttcgcggtga tagttaccaa      7200
     caagtgatcg acgccctgac ggagtatcat gcgagtacgg ttgaacacgc agattacgaa      7260
     ctagaatctg tggaaaaact gctcaacctg cgtaaacaga ttgaaggtta tgtactcggg      7320
     catccggatt ctggccgtgt ggaagcaatg aactcactgt taaatcaggt gaattctcgt      7380
     ctggaagaag tctctgttct tgcggtctct gagcaaagca tcaaagcgca cgatagcttt      7440
     agccgcctat atgaccagct tgataatgcc aacttaaaag aaagtaaaca tctgtatctg      7500
     gatggaaacg gcgatttcgt cactaagggc aaaggcaacc tagccactat cgatcagcta      7560
     ggtggtagcg atgctgtact tgaaaaagta aaagcagccg taactcatga gtatggtcaa      7620
     gtcgttgccg atacgatctt cgcaaggctt tctgcaaacg atctggcaaa agatggtaaa      7680
     ggcattgata ttgctggttt aaacaaagta caccaagcga ttgaacagca catgtcgcca      7740
     gtgagcgcga ccatgtacat ctggaagccg agtgatcaca gcacactagg tcatgccgca      7800
     ttgcaaattg gccaaggtcg cacgcagctt gaaggtcaag ccgctgctga cttcaataag      7860
     cagaattacg tgagttggtg gccactcggt agcaagtcat ccaatatccg caatatcttc      7920
     aacgttgcta cagaagatca gccggatctt aaactacgtt ggagcgattt cagccaacct      7980
     gctcatcaaa atgacacact tgagcacgat atggcatcgg aagaaaacga cggctttggt      8040
     ttgaaagatg gtgaaactaa gctgaaacgc tttatcgaaa aactcaacgc cgcgaaaggt      8100
     attgatgctt catacaaaga tgcttctgaa ggctatgcga gtgtgctact gggcaatcca      8160
     gatatgcttg catcgacagg cattcctgcg catgtattcc agccattcgt cgaccaatgg      8220
     aatgacacca gctacgacat gatggacgta gcaaatcgtt ttgctgaaga gctacagaaa      8280
     caagctcagg caagcggtga cccagccctt gtggaaaaac gtatcgacaa cgtggttcgt      8340
     ctgtttgctg aaagagcgct agaagaaatc gaagccttta aggccagcca agcagatgaa      8400
     ggccgagtgt tccgcattaa cctagaaggg ttggatgtgg cggcgatgca agctgaatgg      8460
     aaccgtctaa gcaacgatcc ggatgctcgc tatcagttat tgaccaaaaa ctgctcaagt      8520
     accgtcgcga aagtgttgaa agcgggtggc gctgacaaac ttattggcca cacatggcga      8580
     cctaagtttg gtgtttggac gccgacagag cttttcaact ttggtcaggc gctgcaggaa      8640
     gctcagcttg aaattgccgc gaagaagcaa agtcatcaag tcactgatgt ccttgatgcc      8700
     ttgtcaggta atgagaagca caaagaaaac gtgacgattg aaaatgatgg cacgccaccg      8760
     cgcgataaag aatctcttag cccactgact cgattcctca acaatgagtt atacggtgag      8820
     aaagacgcac gtcgtaagat tggcgaaatc acgcaaacct tacttgacca tgcggtggaa      8880
     aatggagaat cgcagaaagt taccctcaaa ggggaagcgg gccgtctaac ggggtattac      8940
     catcagggag cggcttcaag cgaaggtgaa acaagtgcga caagcggcaa agtcgtgttg      9000
     ttcttgcacg gttctggttc ttctgctgaa gagcaagcga gcgcgattcg caaccactac      9060
     caaaaacaag gtatcgacat gctcgcagtc aacctgcgtg gctatggtga aagcgacggc      9120
     ggaccaagcg aaaaaggctt gtaccaagac gctcgcacca tgttcaacta cctagtgaac      9180
     gacaagggta ttgatccaag caatatcatc attcacggct actcaatggg tggtccaatt      9240
     gccgcagatt tagcacgtta tgccgcgcaa aacggccaag cggtgtctgg cttattgctt      9300
     gaccgtccta tgccaagcat gaccaaagcc atcaccgctc acgaaatggc gaatccagcg      9360
     ggtattgtgg gggctatcgc gaaagcggtt aacggccaat tctcagtgga gaagaaccta      9420
     aaaggcttgc caaaagagac gccgattctg ctgctaacgg acaacgaagg cttaggtgaa      9480
     gaaggcgaga agctacgagc taaactcgcg attgctggct acaacgtcac gggtgaacaa      9540
     accttctatg gccacgaagc gagcaaccgc ttgatgggtc agtacgcgga tcaaattgtc      9600
     tccggtctgt tcaatgcaga gcaagcagcg gtagaagcgg gcgaagtgct gaaagggcta      9660
     gagaaagact ttaaacgcta tggcgacgcg ctgaaaccag atacgagcgt accgggtaaa      9720
     tcgaaagaca ttcgcaccac taaagatttc ctaaatggtt acaaaaacga tcatgcgaag      9780
     gagatcgttg acggcttccg ctcagatatg agcatcaagc aactggtgga tctgtttgtt      9840
     aaaggcaact ggagtgcaga gcaaaaaggt gcgcttgctt gggaaatcga aagtcgtgca      9900
     ctgaaagtca cgttccagaa caagtctgag aagtacaacc gattgttccg tgagattgct      9960
     tctgctggcg tggtggatgc gaaagcgact gaacagcttg cgccacagtt aatgctgttg     10020
     aacctatcga atgacggttt tggtggacgt tgtgatccac tttctaaact cgttttggtt     10080
     gctaaacagc ttgaaaacga tggtcaagtt ggcgtggcaa gacaactgct ggagaagatg     10140
     tactctgcgg cagctgtgct gagcaatcca accctttact cagacagtga aaaagccaat     10200
     gcaagcaagt tgctcagcag cttggcggcc attcatgcga agaacccaat gcatgatacg     10260
     tcgatgaaag tgtggcagga aaagctggaa gggaagcaag cgctgaccgt aaacggtgtg     10320
     gttgagaaaa tcactgatgc atcggctaac ggtaaacctg tgctgttgga acttgatgct     10380
     ccggggcatg cgatggcagc ttgggcaaaa gactcaggcg acgatcgtgt ttacggcttc     10440
     tacgatccaa atgctggcat tgttgagttc tcgtcggcag agaagtttgg cgactaccta     10500
     acgcgtttct tcggcaagtc cgatctggac atggctcaaa gctataagct aggcaaaaac     10560
     gacgcaggtg aagcaatctt caaccgcgtg gtggtaatgg atggcaacac gttagcaagc     10620
     tacaagccga ccttcggtga taagaccacc atgcagggga tcctcgatct acctgtgttt     10680
     gacgctacac cgattaaaaa gcctacgggt ggagtcgcga gcgatctcga agcattgggt     10740
     gataaaacca aggtcgtggt cgatttagcg caaatcttta cggtgcaaga gctgaaagaa     10800
     agagcaaaag tttttgctaa accgattggc gcatcctacc aaggtattct cgatcaactc     10860
     gaccttgtgc atcaggctaa aggccgcgat caaatcgcag cgagctttga gcttaataag     10920
     aagattaatg actacatcgc tgaacatcca acttcggggc gtaatcaagc gctaacgcag     10980
     ttgaaagagc aggtcaccag tgcgttgttt atcggtaaga tgcaagttgc ccaagcgggt     11040
     attgatgcaa tcgcacaaac aagaccggag cttgccgctc gtatctttat ggtcgcgatt     11100
     gaagaagcca acggtaaaca cgtaggtttg acggacatga tggttcgttg ggccaatgaa     11160
     gacccatact tggcaccgaa gcatggttac aaaggcgaaa cgccaagtga ccttggtttt     11220
     gatgcgaagt accacgtaga tctaggtgag cattacgctg atttcaaaca gtggttagaa     11280
     acgtcccagt cgaacgggtt gttgagtaaa gcgacgttgg atgaatccac taaaacggtt     11340
     catcttggct atagctatca agaacttcag gatttgacgg gtgctgaatc ggtgcaaatg     11400
     gcattctact tcctgaaaga agcggcgaag aaagcggatc cgatttctgg tgattcagct     11460
     gaaatgatac tgctgaagaa atttgcagat caaagctact tatctcaact tgattccgac     11520
     cgaatggatc aaattgaagg tatctaccgc agtagccatg agacggatat tgacgcttgg     11580
     gatcgtcgtt actctggtac aggctatgat gagctgacga ataagcttgc tagcgcaacg     11640
     ggcgttgacg agcagcttgc ggttcttctg gatgatcgta aaggcctctt gattggtgaa     11700
     gtgcatggca gcgacgtcaa cggcctacgc tttgttaatg aacagatgga tgcactgaaa     11760
     aaacagggag tcacagtcat tggccttgag catttacgct cagaccttgc gcaaccgctg     11820
     attgatcgct acctagctac gggtgtgatg tcgagtgaac taagcgcaat gctgaaaaca     11880
     aagcatctcg atgtcactct ttttgaaaac gcacgtgcta acggtatacg catcgtcgcg     11940
     ctggatgcaa acagctctgc gcgtccaaat gttcagggaa cagaacatgg tctgatgtac     12000
     cgtgctggtg ctgcgaacaa cattgcggtg gaagtattac aaaatctgcc tgatggcgaa     12060
     aagttcgttg ctatctacgg taaagcgcat ttgcagtctc acaaagggat tgaagggttc     12120
     gttcctggta tcacgcaccg cctcgatctt cctgcgctta aagtcagtga ctcgaaccag     12180
     ttcacagttg aacaagacga tgtgagtcta cgtgttgtct acgatgatgt tgctaacaaa     12240
     ccgaagatca cgttcaagga cagtttgagt ggcgcaaata ccgctcttca caaccaaaat     12300
     gtgaatgact gggaacgtgt tgttgtgact ccgacagcgg acggcggtga aagccgtttt     12360
     gatggtcaaa tcatcgtgca aatggagaac gatgatgtcg tggcaaaagc cgctgcgaac     12420
     cttgcgggta agcacccaga aagcagtgtg gtggtgcaga tcgattcaga cggcaactat     12480
     cgcgtggtgt atggcgatcc gtcaaagctg gatggaaagc tacgttggca gttagtaggt     12540
     catggtcgag atgactcaga aagtaacaac acgcgtttaa gtggctacag tgccgatgag     12600
     ctggcagtga aattggccaa gttccaacag tcgtttaatc aagcggaaaa catcaacaat     12660
     aagcctgacc atatcagtat tgttggttgt tctttggtga gtgacgacaa gcaaaaaggc     12720
     tttggtcatc agtttattaa cgcgatggat gcgaatggtc ttcgtgtcga tgtctctgta     12780
     cgcagttctg aactggccgt agacgaggca gggcgtaaac ataccaagga cgcgaatggc     12840
     gattgggtcc aaaaagccga aaacaacaaa gtttcgctaa gctgggacga gcaaggtgaa     12900
     gttgttgcca aggatgaacg tattcgcaat ggtattgcgg aaggcgacat cgatctctct     12960
     cgcattggtg tcagcgacgt tgacgagcca gctcgtggtg caatcggtga caacaatgat     13020
     gtgtttgatg cgccagaaaa acgcaaagcg gagacagaaa cctcatcttc ttctgcaaac     13080
     aataaactca gctactcagg taacattcaa gtcaatgtgg gtgatggtga gtttacggca     13140
     gtgaactggg gcacatcgaa tgtgggcatt aaagtcggca cgggtggctt taagtcgctg     13200
     gcctttggtg acaataacgt catggttcac atcggcaatg gtgagagcaa gcacagcttc     13260
     gatattggtg gttatcaggc actggaaggt gcgcaaatgt tcatcggtaa tcgtaatgtg     13320
     agcttcaact taggtcgaag taatgatctg attgtgatga tggacaagtc aattccgact     13380
     ccgccattgg ttaatccgtt cgatggtgcc gctcgtattt cgggcgtact gcaaagcatt     13440
     gccacctcgg gtgagggcca agattggcta gcggctcaag agcagcaatg gacattgtct     13500
     ggcgccaaga agtttgtcaa agatatgtct ggtttggatc agagcagcag cgttgattac     13560
     accagtttgg ttgaactaga ctcgcagaac gagcgaagca gccgtggctt gaagcacgat     13620
     gcagaagcgg ctctgaacaa gcagtacaat caatggttaa gtggcaatag cgattctgac     13680
     accagcaagc tcagccgcgc agataagctt cgtcaagcca atgaaaagct tgcgtttaac     13740
     tttgccgtgg gtggtcaagg tgcggatatc caagtcacga caggtaactg gaacttcatg     13800
     tttggtgaca acatccagtc tattttggat accaacctag gttcactgtt tggcctcatg     13860
     acacagcagt tctctgctac gggtcaggcc aagacaacct tcacctacac gccagaagat     13920
     ttgcctcgtc agcttaagaa caagctactt gggcagttag cgggtgtagg agccgagacc     13980
     acgctagcgg atatttttgg tgtggattac accgcgtcag gtcaaattgt ttcgcgtaat     14040
     ggtgaagctg tcgatggtgt agcgattctc aaagagatgt tggaggtcat tggtgagttc     14100
     agtggtgatc aactgcaagc ctttgtcgac ccagctaagt tactggatag cttgaagtcg     14160
     ggtatcaaca tgggtgcgga tggcattaag tcttttgctg aaactcatgg actgaaagag     14220
     aaggcgccag aagaggaaga ggacaactct tcggtttctg ttaatggtgc gagcgtaaac     14280
     agtgcgcaag gcgcgacggt ggctgatggc agcactgaaa cagcagaaac accagatcgt     14340
     gcctttggct ttaactcgct taacctgccg aacttgttcg ccactatctt tagtcaagac     14400
     aagcagaaag agatgaaatc gctggtggaa aatctcaaag agaatctcac cgctgatctg     14460
     ctgaatatga aagagaaaac gtttgatttc cttcgtaaca gtggtcatct ccaaggtgat     14520
     ggcgatatca acatctccct aggaaactac aacttcaact ggggtggcga tggtaaagat     14580
     ctcggagcgt atctaggaga caacaacaac ttctggggcg gacgaggcga tgatgtgttc     14640
     tacgcaacag gcacgtcaaa catcttcacg ggcggcgaag gcaacgacat gggcgttctg     14700
     atgggacgtg aaaacatgat gtttggcggt gatggcaacg acacagcagt ggttgcagga     14760
     cgcattaacc atgtcttcct tggtgccggt gatgaccagt cgtttgtctt tggtgagggc     14820
     ggtgaaattg acaccggttc aggccgcgac tacgtggtga cgtctggcaa cttcaaccgt     14880
     gtggatacgg gggatgatca agactactcc gttacgattg gcaacaacaa ccaagtagag     14940
     ctaggcgctg gcaatgactt tgctaatgtc ttcggtaact acaaccgtat caatgcaagc     15000
     gctggcaacg atgttgtgaa gctaatgggc tatcacgccg tgttgaatgg tggtgagggc     15060
     gaggaccatc tcatcgcagc agccatctct aagttcagcc aattcaacgg tggcgaaggg     15120
     cgcgatctga tggtgttggg tggttatcaa aacacgttca aaggtggcac ggatgtggac     15180
     agctttgtgg tgagcggtga tgttatcgac aaccttgttg aagacattcg cagcgaagat     15240
     aacattgtct tcaatggcat cgattggcag aaactgtggt tcgaacgcag cggatatgac     15300
     ctgaagttgt ctattcttcg tgacccggca agtgacagtg accaagcgaa gtttgagcat     15360
     attggttcgg tgacgttcag tgattacttt aacggtaatc gagcgcaggt gatcatcgca     15420
     atgggtgaga aagacgcgac gggtgaacgt gagtacacca ccttgtctga gagtgcaatt     15480
     gatgcgctgg tacaagccat gagtggcttt gaccctcagg cgggtgacaa tggattcatg     15540
     gataacctag acagcaaatc tcgtgtggcg attaccactg cgtgggcaga cgttgtccat     15600
     aaaaagggta taacggtgta a                                               15621
//