ID POB49698; SV 1; linear; genomic DNA; WGS; PRO; 15621 BP. XX PA PDGH01000027.1 XX PR Project:PRJNA413285; XX DT 09-MAR-2018 (Rel. 136, Created) DT 09-MAR-2018 (Rel. 136, Last updated, Version 1) XX DE Vibrio vulnificus RTX toxin XX KW WGS. XX OS Vibrio vulnificus OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; OC Vibrio. XX RN [1] RC Publication Status: Online-Only RX PUBMED; 29358930. RA Roig F.J., Gonzalez-Candelas F., Sanjuan E., Fouz B., Feil E.J., RA Llorens C., Baker-Austin C., Oliver J.D., Danin-Poleg Y., Gibas C.J., RA Kashi Y., Gulig P.A., Morrison S.S., Amaro C.; RT "Phylogeny of Vibrio vulnificus from the Analysis of the Core-Genome: RT Implications for Intra-Species Taxonomy"; RL Front Microbiol. 8:2613-2613(2018). XX RN [2] RA Roig F.J.; RT ; RL Submitted (06-OCT-2017) to the INSDC. RL Microbiology and Ecology, University of Valencia, Dr. moliner, 50, RL Burjassot, Valencia 46100, Spain XX DR MD5; 034844f138cf48c0276e8c6ef2a2fc54. DR BioSample; SAMN07739079. XX FH Key Location/Qualifiers FH FT source 1..15621 FT /organism="Vibrio vulnificus" FT /strain="CECT4608" FT /mol_type="genomic DNA" FT /country="Spain" FT /isolation_source="Eel tank water" FT /collection_date="1990" FT /note="biotype: 1" FT /db_xref="taxon:672" FT CDS PDGH01000027.1:87649..103269 FT /codon_start=1 FT /transl_table=11 FT /locus_tag="CRN52_02910" FT /product="RTX toxin" FT /note="Derived by automated computational analysis using FT gene prediction method: Protein Homology." FT /db_xref="InterPro:IPR008979" FT /db_xref="InterPro:IPR011049" FT /db_xref="InterPro:IPR011509" FT /db_xref="InterPro:IPR020972" FT /db_xref="InterPro:IPR020974" FT /db_xref="InterPro:IPR022742" FT /db_xref="InterPro:IPR029058" FT /db_xref="InterPro:IPR038383" FT /db_xref="PDB:2N9W" FT /db_xref="UniProtKB/TrEMBL:A0A2S3R7M0" FT /inference="COORDINATES:similar to AA FT sequence:RefSeq:WP_011081430.1" FT /protein_id="POB49698.1" FT /translation="MGKPFWRSVEYFFTGNYSADDGNNSIVAIGFGGEIHAYGGDDHVT FT VGSIGATVYTGSGNDTVVGGSAYLRVEDTTGHLSVKGAAGYADINKSGDGNVSFAGAAG FT GVSIDHLGNNGDVSYGGAAAYNGITRKGLSGNVTFKGAGGYNALWHETNQGNLSFAGAG FT AGNKLDRTWFNRYQGSRGDVTFDGAGAANSISSRVETGNITFRGAGADNHLVRKGKVGD FT ITLQGAGASNRIERTRQAEDVYAQTRGNIRFEGVGGYNSLYSDVAHGDIHFSGGGAYNT FT ITRKGSGSSFDAQGMEYAKAEDIVLTAAQMHGLSIDNGNKFHAVTAVKSEREPNTYLFA FT IADGTYTKINKVRLYNDPETGKLKYYSEAWFKRGNHLAELARSDVSSAGGFEVNPINGG FT YTLANIAVEHQQSVTVHAVEKNLTEYEWVTYANGTLIDAKDVALSEAKMGGHAISTDGT FT TVDVQAVKSNRKPNTYVYAKVLGPYTKIVVVELANDPKTGALKYQARSWYKEGDHTANL FT ANEDISSANGYHSMGKGGYSLSDLHYSVNAVRSTSETVADIDEYTDQTLFKPATDSGES FT SGDVRFNGAGGGNVIKSNVTRGNVYFNGGGIANVILHSSQFGNTEFNGGGAANVIVKSG FT EEGDLTFRGAGLANVLVHQSKQGKMDVYAGGAVNVLVRIGDGQYLAHLLAYGNISVHKG FT NGNSRVVMLGGYNTHTQIGSGNGLWLAAGGFNVMTQVGKGDVASVLAGGANVLTKVGDG FT DLTAGMLGGANVITHISGDNETSNTTAVALGGANILTKKGKGNTLAVMGGGANVLTHVG FT DGTTTGVMVGGANILTKVGNGDTTGIMLGVGNVLTHVGDGQTLGVMGAAGNIFTKVGDG FT TSIAVMIGAGNIFTHVGEGNAWALMGGLGNVFTKVGNGDALALMVAEANVFTHIGDGMS FT VALMLAKGNVATKVGNGTTLAAMVGNANIFTHVGSGSTFAAMIGQANIMTKVGNDLTAA FT LMVGKANIYTHVGDGTSLGIFAGEVNVMTKIGNGTTLAAMFGKANIMTHVGDGLTGVLA FT LGEANIVTKVGDDFMGVVAAAKANVVTHVGDATTAAVLAGKGNILTKVGEGTTVGLLIS FT DIGNVMTHVGDGTTIGIAKGKANIITKVGDGLGVNVAWGQANVFTQVGDGDRYNFAKGE FT ANIITKVGDGKEVSVVQGKANIITHVGNGDDYTGAWGKANVITKVGNGRNVVLAKGEAN FT IVTQVGDGDSFNALWSKGNIVTKVGDGMQVTAAKGKANITTTVGDGLSVTAAYGDANIN FT TKVGDGVSVNVAWGKYNINTKVGDGLNVAVMKGKANANIHVGDGLNINASYAQNNVAIK FT VGNGDFYSLAVASSNTSSNKLSALFDNIKQTLLGVGGSQAINYLVQGDEASSSGTQKGR FT GAIATPEITKLDGFQMEAIEEVGSDLGDSLTGSVTKVDTPDLNKMQNALDVDGSSDQTQ FT APNLIVNGDFEQGDRGWKSTHGVEASYSGNVYGVNGEGHGARVTELDTYTNTSLYQDLT FT DLTEGEVIAVSFDFAKRAGLSNNEGIEVLWNGEVVFSSSGDASAWQQKTLKLTAHAGSN FT RIEFKGTGHNDGLGYILDNVVAKSESSQQANAVSEHATQNQASQNALSDKERAEADRQR FT LEQEKQKQLDAVAGSQSQLESTDQQALGNNGQAQRDAVKEESEAVTAELTKLAQGLDVL FT DGQATHTGESGDQWRNDFAGGLLDGVQSQLDDAKQLANDKIAAAKQTQSDNNSKVKESV FT AKSEAGVAQGEQNRAGAEQDIAEAKADAETRKADAVAKSNDAKQAESDAHSAANDAQSR FT GDRDAMNAENKANQAQNDAKGTKQNEGDRPDREGVAGSGLSGNAHSVEGAGETGSHITT FT DSQTNADGRFSEGLSEQEQEALEGATNAVNRLQINAGIRGKNSGSTITSMFTETNSDSI FT VVPTTASQDVVRKEIRISGVNLEGLGEASHDSAESLVAARAEKVANLYRWLDTDNDVAT FT DKYVPVPGFERVDVDVSDEVKQRMIQSMSGYIEHTDNQVPKDQAEALATLFVESTLDYD FT WDKRVEFLTKLESYGYSFEAPHAEKSIVSFWSGKNFKQYRDILDNAQTDGKKVVYDIDV FT KGNAFAIDLNKHLMRWGGLFLDPDNAEQNQLKSSIDAATFSNTGFWSSVYATGAQNDVY FT VIAEGGVRLGNYFWNVELPALRQLQREGLVGEIRLLDKPVSEYKDLPADQIGRRLTDAG FT VAVKVRFDALSHERQAELLADNPDGYKADTLVELDVKLSAIDSMLRESLPFYSLRTERN FT LLVQEGEEGFEVRSWPGIDGKSKTILLDNPEDAAQQKSIERFILANFDNFEQMPDELFL FT VDNKVLSHHDGRTRIIAQKEDGAWTYNTNVELMSVTELLDAAHVNGKVRGDSYQQVIDA FT LTEYHASTVEHADYELESVEKLLNLRKQIEGYVLGHPDSGRVEAMNSLLNQVNSRLEEV FT SVLAVSEQSIKAHDSFSRLYDQLDNANLKESKHLYLDGNGDFVTKGKGNLATIDQLGGS FT DAVLEKVKAAVTHEYGQVVADTIFARLSANDLAKDGKGIDIAGLNKVHQAIEQHMSPVS FT ATMYIWKPSDHSTLGHAALQIGQGRTQLEGQAAADFNKQNYVSWWPLGSKSSNIRNIFN FT VATEDQPDLKLRWSDFSQPAHQNDTLEHDMASEENDGFGLKDGETKLKRFIEKLNAAKG FT IDASYKDASEGYASVLLGNPDMLASTGIPAHVFQPFVDQWNDTSYDMMDVANRFAEELQ FT KQAQASGDPALVEKRIDNVVRLFAERALEEIEAFKASQADEGRVFRINLEGLDVAAMQA FT EWNRLSNDPDARYQLLTKNCSSTVAKVLKAGGADKLIGHTWRPKFGVWTPTELFNFGQA FT LQEAQLEIAAKKQSHQVTDVLDALSGNEKHKENVTIENDGTPPRDKESLSPLTRFLNNE FT LYGEKDARRKIGEITQTLLDHAVENGESQKVTLKGEAGRLTGYYHQGAASSEGETSATS FT GKVVLFLHGSGSSAEEQASAIRNHYQKQGIDMLAVNLRGYGESDGGPSEKGLYQDARTM FT FNYLVNDKGIDPSNIIIHGYSMGGPIAADLARYAAQNGQAVSGLLLDRPMPSMTKAITA FT HEMANPAGIVGAIAKAVNGQFSVEKNLKGLPKETPILLLTDNEGLGEEGEKLRAKLAIA FT GYNVTGEQTFYGHEASNRLMGQYADQIVSGLFNAEQAAVEAGEVLKGLEKDFKRYGDAL FT KPDTSVPGKSKDIRTTKDFLNGYKNDHAKEIVDGFRSDMSIKQLVDLFVKGNWSAEQKG FT ALAWEIESRALKVTFQNKSEKYNRLFREIASAGVVDAKATEQLAPQLMLLNLSNDGFGG FT RCDPLSKLVLVAKQLENDGQVGVARQLLEKMYSAAAVLSNPTLYSDSEKANASKLLSSL FT AAIHAKNPMHDTSMKVWQEKLEGKQALTVNGVVEKITDASANGKPVLLELDAPGHAMAA FT WAKDSGDDRVYGFYDPNAGIVEFSSAEKFGDYLTRFFGKSDLDMAQSYKLGKNDAGEAI FT FNRVVVMDGNTLASYKPTFGDKTTMQGILDLPVFDATPIKKPTGGVASDLEALGDKTKV FT VVDLAQIFTVQELKERAKVFAKPIGASYQGILDQLDLVHQAKGRDQIAASFELNKKIND FT YIAEHPTSGRNQALTQLKEQVTSALFIGKMQVAQAGIDAIAQTRPELAARIFMVAIEEA FT NGKHVGLTDMMVRWANEDPYLAPKHGYKGETPSDLGFDAKYHVDLGEHYADFKQWLETS FT QSNGLLSKATLDESTKTVHLGYSYQELQDLTGAESVQMAFYFLKEAAKKADPISGDSAE FT MILLKKFADQSYLSQLDSDRMDQIEGIYRSSHETDIDAWDRRYSGTGYDELTNKLASAT FT GVDEQLAVLLDDRKGLLIGEVHGSDVNGLRFVNEQMDALKKQGVTVIGLEHLRSDLAQP FT LIDRYLATGVMSSELSAMLKTKHLDVTLFENARANGIRIVALDANSSARPNVQGTEHGL FT MYRAGAANNIAVEVLQNLPDGEKFVAIYGKAHLQSHKGIEGFVPGITHRLDLPALKVSD FT SNQFTVEQDDVSLRVVYDDVANKPKITFKDSLSGANTALHNQNVNDWERVVVTPTADGG FT ESRFDGQIIVQMENDDVVAKAAANLAGKHPESSVVVQIDSDGNYRVVYGDPSKLDGKLR FT WQLVGHGRDDSESNNTRLSGYSADELAVKLAKFQQSFNQAENINNKPDHISIVGCSLVS FT DDKQKGFGHQFINAMDANGLRVDVSVRSSELAVDEAGRKHTKDANGDWVQKAENNKVSL FT SWDEQGEVVAKDERIRNGIAEGDIDLSRIGVSDVDEPARGAIGDNNDVFDAPEKRKAET FT ETSSSSANNKLSYSGNIQVNVGDGEFTAVNWGTSNVGIKVGTGGFKSLAFGDNNVMVHI FT GNGESKHSFDIGGYQALEGAQMFIGNRNVSFNLGRSNDLIVMMDKSIPTPPLVNPFDGA FT ARISGVLQSIATSGEGQDWLAAQEQQWTLSGAKKFVKDMSGLDQSSSVDYTSLVELDSQ FT NERSSRGLKHDAEAALNKQYNQWLSGNSDSDTSKLSRADKLRQANEKLAFNFAVGGQGA FT DIQVTTGNWNFMFGDNIQSILDTNLGSLFGLMTQQFSATGQAKTTFTYTPEDLPRQLKN FT KLLGQLAGVGAETTLADIFGVDYTASGQIVSRNGEAVDGVAILKEMLEVIGEFSGDQLQ FT AFVDPAKLLDSLKSGINMGADGIKSFAETHGLKEKAPEEEEDNSSVSVNGASVNSAQGA FT TVADGSTETAETPDRAFGFNSLNLPNLFATIFSQDKQKEMKSLVENLKENLTADLLNMK FT EKTFDFLRNSGHLQGDGDINISLGNYNFNWGGDGKDLGAYLGDNNNFWGGRGDDVFYAT FT GTSNIFTGGEGNDMGVLMGRENMMFGGDGNDTAVVAGRINHVFLGAGDDQSFVFGEGGE FT IDTGSGRDYVVTSGNFNRVDTGDDQDYSVTIGNNNQVELGAGNDFANVFGNYNRINASA FT GNDVVKLMGYHAVLNGGEGEDHLIAAAISKFSQFNGGEGRDLMVLGGYQNTFKGGTDVD FT SFVVSGDVIDNLVEDIRSEDNIVFNGIDWQKLWFERSGYDLKLSILRDPASDSDQAKFE FT HIGSVTFSDYFNGNRAQVIIAMGEKDATGEREYTTLSESAIDALVQAMSGFDPQAGDNG FT FMDNLDSKSRVAITTAWADVVHKKGITV" XX SQ Sequence 15621 BP; 4318 A; 3457 C; 4305 G; 3541 T; 0 other; atgggaaaac cattttggag aagtgttgaa tacttcttca cagggaacta ttccgccgac 60 gatggaaaca acagtattgt tgctatcggt tttggtggag aaatccatgc ctacggtggt 120 gatgatcatg tcactgtcgg atcgattggt gcaacggttt ataccggcag cggcaatgat 180 acggtcgtag gcggttcggc atatctaaga gtggaagaca ccactgggca cctttctgta 240 aaaggcgcag ctgggtatgc agacattaat aaaagtggcg atggcaatgt gtcattcgct 300 ggtgccgctg gcggtgtgtc gattgaccac ttaggtaata atggtgatgt cagttacggc 360 ggtgccgcgg cttataatgg cattacccgc aaaggtttga gcggcaacgt cacctttaaa 420 ggcgctggcg gttacaatgc cctttggcat gaaaccaacc aaggtaatct ctcttttgct 480 ggcgcaggag cgggcaataa actagaccgt acttggttca accgttatca aggctcgcgt 540 ggtgatgtga cgtttgatgg cgctggcgcg gcaaacagca ttagttcacg tgttgaaacc 600 ggcaacatta ctttccgtgg ggctggtgct gacaaccatt tggtccgtaa aggcaaagtg 660 ggcgatatta ccttgcaagg tgcgggcgca tcaaaccgta ttgagcgtac acgccaagcg 720 gaagatgttt acgcgcaaac acgcggtaac attcgctttg aaggtgtcgg cggttacaac 780 agcctttact ccgatgtggc acacggtgac atccatttct ccggtggcgg tgcttataac 840 accattacac gaaaaggcag tggtagtagc ttcgatgctc aaggtatgga atacgcgaaa 900 gcggaagaca ttgttctcac cgcggcgcag atgcatggtt tatcgattga taacggcaac 960 aagttccatg cggttaccgc tgtaaagtca gagcgggagc caaatactta tctgtttgct 1020 atcgcagatg gtacttacac caaaatcaac aaagttcgtc tctataacga tccagaaacg 1080 ggcaaactca aatactactc tgaggcttgg tttaagcgcg gcaatcattt agctgagctt 1140 gctcgttccg atgtctcttc tgctggtggt tttgaagtta atccaatcaa tggtggttac 1200 acccttgcta atattgccgt tgagcatcag caatcagtga cggttcatgc cgttgaaaaa 1260 aatctgactg aatatgagtg ggtgacctac gccaatggca cactgattga tgcgaaagat 1320 gtggcattgt cagaggcgaa aatgggcggt cacgccatct cgaccgatgg gacgacagtc 1380 gatgttcaag cggtgaaatc aaaccgtaaa ccaaacactt atgtttacgc aaaagtgctt 1440 gggccttaca caaaaattgt ggtggttgaa cttgctaatg atcccaaaac aggggcgctt 1500 aagtatcaag ctcgctcttg gtacaaagag ggtgatcata ccgcaaacct agccaatgaa 1560 gatatttcgt ctgcaaacgg atatcactcg atgggcaaag gcggctactc actcagcgat 1620 ctgcattaca gtgtgaacgc ggtaagaagt accagcgaaa ccgtggccga catcgacgag 1680 tacaccgatc aaaccttgtt taagccagcg accgatagcg gtgaaagctc tggtgatgtg 1740 cgcttcaatg gtgcgggtgg cggtaacgtc atcaagtcca atgtgactcg cggcaatgtc 1800 tactttaatg gtggcggtat cgctaacgtc atcctccaca gttcgcaatt tggtaatacc 1860 gagttcaacg gtggtggcgc ggcaaacgtg attgtcaaaa gtggcgaaga aggggatctc 1920 accttccgcg gcgcgggttt ggcgaacgtg ttggtacacc aaagcaagca aggcaagatg 1980 gatgtttacg cgggcggtgc ggtaaacgta ctggttcgta ttggcgatgg tcaatacctt 2040 gcgcatttgc tggcttacgg caacatttcc gtgcacaaag gcaatggcaa cagccgtgtc 2100 gttatgctcg gtggttacaa cacccatacc caaattggct ccggcaacgg cttgtggttg 2160 gcggcgggcg gcttcaacgt gatgacgcaa gtgggtaaag gtgatgtagc atcggtactg 2220 gctggcggcg cgaacgtgct caccaaagtg ggtgacggcg atctaaccgc aggtatgttg 2280 ggcggcgcaa acgtgattac ccacatcagc ggcgacaatg aaacctcgaa taccacagcc 2340 gtagccttag gcggtgccaa cattctcacc aaaaaaggca aagggaatac ccttgcggtg 2400 atgggcggtg gcgcaaacgt gctgacgcat gtgggtgatg gtacaacaac tggcgtaatg 2460 gtcggtggag cgaacattct caccaaagta ggtaacggcg acacgaccgg cataatgctt 2520 ggtgttggca acgtgctaac gcatgttggt gatggccaaa ctcttggtgt gatgggcgca 2580 gcgggtaaca tcttcaccaa agtcggtgat ggaacctcta ttgcggtcat gattggtgct 2640 ggcaacatct tcacccatgt gggagaaggg aatgcttggg cgctgatggg cggcttgggt 2700 aacgtcttta ccaaagtcgg caacggtgat gcgctagcct taatggtggc agaagccaac 2760 gtcttcactc acattggtga tggtatgtcg gtcgcactga tgttagccaa aggcaacgtt 2820 gcgacaaaag tgggtaatgg aaccacactc gctgcaatgg ttggtaacgc caatatcttc 2880 actcacgtag gcagtggcag tacgtttgct gcaatgatcg gccaagccaa catcatgacc 2940 aaagtgggca atgatctcac cgcggcactg atggtcggta aagcaaatat ctacacacat 3000 gtcggtgatg gaaccagcct aggaatattc gcgggcgaag tgaacgtgat gactaagatc 3060 ggtaacggca caaccttggc ggcgatgttc ggtaaagcca acatcatgac gcatgtcggc 3120 gatggtctaa cgggcgtgtt agcactgggc gaagccaata ttgtcaccaa agtgggtgat 3180 gatttcatgg gggttgtggc ggcagcaaaa gccaacgtcg tgactcatgt tggtgatgca 3240 acaaccgcgg ctgtgttggc tggtaaaggc aatatcctaa ccaaagtggg tgaaggcacc 3300 acggtagggt tgttgatttc cgatatcggc aacgtaatga cccacgtcgg agatggcacg 3360 accattggta ttgccaaagg caaggcaaac atcattacca aagtcggtga tggtttgggc 3420 gtcaatgtcg cttgggggca agcaaacgtg tttacccaag tgggcgacgg tgatcgctat 3480 aactttgcca aaggtgaagc caacatcatc actaaagtgg gtgatggcaa agaagtctcc 3540 gtggtgcaag gtaaagccaa catcattact catgtgggca atggcgacga ctacaccgga 3600 gcttggggta aagcgaacgt cattactaaa gtgggtaatg gccgtaacgt ggtactggca 3660 aaaggtgaag ccaatattgt gacccaagta ggtgatggcg acagctttaa cgcactttgg 3720 agcaaaggca acattgtcac caaagtgggt gatggtatgc aggtgacggc agcaaaaggc 3780 aaagccaaca tcaccaccac cgttggtgat ggcttgagtg tgacagccgc ctatggtgac 3840 gccaacatca ataccaaagt cggtgatggt gtatccgtca acgtcgcttg gggcaaatat 3900 aacatcaaca cgaaagtggg tgatggcctg aatgttgccg tgatgaaagg caaagctaac 3960 gccaatattc acgtgggcga tggcctcaac atcaatgcct cttacgcaca aaacaacgtt 4020 gcaatcaaag ttggtaacgg cgatttttac agtttggcag ttgcgtcaag caacaccagc 4080 agcaacaagc tctcggcact gtttgataac attaaacaaa ccctacttgg tgtgggtggt 4140 agccaagcaa tcaactactt ggttcaaggt gatgaagcat cgtcatccgg tacgcaaaaa 4200 ggccgtggtg cgattgcaac accggaaatc accaagctgg atggtttcca aatggaagcc 4260 attgaagaag tgggctcgga cttgggcgat agtctaaccg gcagtgtcac caaggtagat 4320 accccagatc tcaacaagat gcaaaatgca ctcgacgttg acggatcttc tgatcaaact 4380 caagctccga atctcattgt gaatggtgat tttgagcaag gtgatcgtgg ttggaaatcg 4440 acacacggtg ttgaagcttc ctattcgggc aatgtctatg gcgtgaacgg cgaaggtcac 4500 ggcgcacgtg tgacggaact ggatacctac accaacacca gtctctatca agatctgacc 4560 gatcttacgg aaggtgaagt cattgctgtg agctttgatt ttgcgaaacg tgcaggtcta 4620 tcgaataacg aaggcattga agttctttgg aatggcgaag tcgtcttctc atcgtctggt 4680 gatgcctctg cttggcagca aaaaacctta aaactgaccg cgcatgctgg cagtaaccga 4740 atcgaattca aaggcacagg ccacaatgat ggactgggct atatcctaga taatgtcgtg 4800 gcgaaatcgg aatcgtcgca acaagccaac gcagtgagtg agcacgcgac acaaaatcaa 4860 gcgtcgcaga atgccctatc agataaagag cgcgcagaag cggatcgcca acgtcttgaa 4920 caagaaaagc agaaacagct tgatgctgtc gcagggtcac aaagtcagtt ggagtcgacc 4980 gaccaacaag cgctaggaaa taacggtcaa gctcaacgtg atgcggtgaa agaagagtcg 5040 gaagccgtga ccgccgagtt gacaaaactg gcgcaaggtc tcgatgtgct tgatggccaa 5100 gcaacgcata ctggcgagtc aggcgaccaa tggcgcaatg attttgccgg tggtctgctc 5160 gatggcgttc aaagccagct cgacgatgcc aagcaactcg cgaatgacaa gattgctgca 5220 gcgaagcaga cgcagtctga caataacagc aaagtcaaag aatccgttgc gaaatctgaa 5280 gcgggtgtgg cacaaggtga gcaaaatcgc gcaggtgcag agcaagacat tgccgaagct 5340 aaagccgatg cagaaacacg caaagccgat gctgtggcga agagtaacga tgcgaaacag 5400 gccgaatctg acgcacacag cgccgcaaac gacgcgcaat cgcgtggtga tcgcgatgcg 5460 atgaatgccg aaaacaaagc caaccaagcg cagaatgatg ccaaagggac caagcaaaac 5520 gaaggcgatc gccctgaccg tgaaggcgtg gctggcagcg gtctttcagg caacgctcat 5580 agcgtggaag gtgctggcga aacgggcagt catatcacca ctgacagcca aacaaacgcc 5640 gatggtcgat tcagtgaagg tctgagcgaa caagagcaag aagcgctgga aggtgcgaca 5700 aacgcagtga accgtctgca aattaacgca ggtattcgcg gaaagaacag cggtagcaca 5760 atcacctcaa tgttcaccga aacaaactcc gacagcattg tggtaccaac cactgcgtct 5820 caggatgtgg ttcgaaaaga gattcgcatt tctggggtga atttagaggg gcttggtgaa 5880 gcttcgcatg actctgctga atcgcttgtg gctgctcgcg cggaaaaagt ggcgaatctc 5940 tatcgctggc tagacactga taatgacgtg gcgacggaca agtatgtacc tgtccctggc 6000 tttgaacgcg tcgatgttga tgtctctgat gaagtcaagc agcgcatgat tcaatctatg 6060 agcggttaca tcgaacacac cgacaatcaa gtaccgaaag atcaagcgga agcattagcc 6120 actttgtttg ttgaatcgac gctcgattat gactgggaca aacgcgttga gtttctcact 6180 aagcttgaga gctatggtta tagttttgaa gcgccacacg cagagaaaag cattgtttcc 6240 ttctggtctg gtaaaaactt caagcaatac cgagacattc tcgacaatgc ccagactgat 6300 ggcaaaaagg tcgtgtacga catcgatgtt aaaggcaacg catttgcaat cgacctgaat 6360 aagcatttaa tgcgttgggg cggcctgttc cttgacccag ataacgccga gcaaaatcag 6420 ttgaaatcat caatcgatgc agcaacgttc agcaatacag gtttttggag ttcggtctat 6480 gcgacggggg cacaaaatga tgtgtatgtc atcgcagaag gtggtgtgcg tcttggcaac 6540 tatttctgga atgttgagct acctgcatta cgccaattgc agcgtgaagg gttagtcggt 6600 gaaattcgac tgcttgataa gccagtatcc gagtacaaag atctaccagc agaccagatt 6660 ggacgccgac ttaccgatgc aggtgttgcc gttaaagtac gctttgatgc gttgagtcac 6720 gagagacaag ctgagctttt ggccgacaat ccagatggtt acaaagccga tacgctggtt 6780 gagttggatg tgaagctaag tgcgatcgat agcatgttgc gtgaatctct accattctat 6840 tcacttcgta ctgagcgcaa cctcttagtg caagaaggcg aagaaggatt tgaagttcgc 6900 tcatggccgg gaatcgatgg aaagagcaag actattctgc ttgataaccc agaagatgca 6960 gctcaacaaa aatccattga gcgctttatc ttggcaaact tcgacaactt cgagcagatg 7020 ccagatgaac ttttcttagt ggataacaag gtgctctcgc atcacgatgg ccgcacgcga 7080 attatagcgc aaaaagaaga cggtgcttgg acgtacaaca ccaatgttga actgatgtct 7140 gtcactgagc tactcgatgc tgctcatgtg aacggtaaag ttcgcggtga tagttaccaa 7200 caagtgatcg acgccctgac ggagtatcat gcgagtacgg ttgaacacgc agattacgaa 7260 ctagaatctg tggaaaaact gctcaacctg cgtaaacaga ttgaaggtta tgtactcggg 7320 catccggatt ctggccgtgt ggaagcaatg aactcactgt taaatcaggt gaattctcgt 7380 ctggaagaag tctctgttct tgcggtctct gagcaaagca tcaaagcgca cgatagcttt 7440 agccgcctat atgaccagct tgataatgcc aacttaaaag aaagtaaaca tctgtatctg 7500 gatggaaacg gcgatttcgt cactaagggc aaaggcaacc tagccactat cgatcagcta 7560 ggtggtagcg atgctgtact tgaaaaagta aaagcagccg taactcatga gtatggtcaa 7620 gtcgttgccg atacgatctt cgcaaggctt tctgcaaacg atctggcaaa agatggtaaa 7680 ggcattgata ttgctggttt aaacaaagta caccaagcga ttgaacagca catgtcgcca 7740 gtgagcgcga ccatgtacat ctggaagccg agtgatcaca gcacactagg tcatgccgca 7800 ttgcaaattg gccaaggtcg cacgcagctt gaaggtcaag ccgctgctga cttcaataag 7860 cagaattacg tgagttggtg gccactcggt agcaagtcat ccaatatccg caatatcttc 7920 aacgttgcta cagaagatca gccggatctt aaactacgtt ggagcgattt cagccaacct 7980 gctcatcaaa atgacacact tgagcacgat atggcatcgg aagaaaacga cggctttggt 8040 ttgaaagatg gtgaaactaa gctgaaacgc tttatcgaaa aactcaacgc cgcgaaaggt 8100 attgatgctt catacaaaga tgcttctgaa ggctatgcga gtgtgctact gggcaatcca 8160 gatatgcttg catcgacagg cattcctgcg catgtattcc agccattcgt cgaccaatgg 8220 aatgacacca gctacgacat gatggacgta gcaaatcgtt ttgctgaaga gctacagaaa 8280 caagctcagg caagcggtga cccagccctt gtggaaaaac gtatcgacaa cgtggttcgt 8340 ctgtttgctg aaagagcgct agaagaaatc gaagccttta aggccagcca agcagatgaa 8400 ggccgagtgt tccgcattaa cctagaaggg ttggatgtgg cggcgatgca agctgaatgg 8460 aaccgtctaa gcaacgatcc ggatgctcgc tatcagttat tgaccaaaaa ctgctcaagt 8520 accgtcgcga aagtgttgaa agcgggtggc gctgacaaac ttattggcca cacatggcga 8580 cctaagtttg gtgtttggac gccgacagag cttttcaact ttggtcaggc gctgcaggaa 8640 gctcagcttg aaattgccgc gaagaagcaa agtcatcaag tcactgatgt ccttgatgcc 8700 ttgtcaggta atgagaagca caaagaaaac gtgacgattg aaaatgatgg cacgccaccg 8760 cgcgataaag aatctcttag cccactgact cgattcctca acaatgagtt atacggtgag 8820 aaagacgcac gtcgtaagat tggcgaaatc acgcaaacct tacttgacca tgcggtggaa 8880 aatggagaat cgcagaaagt taccctcaaa ggggaagcgg gccgtctaac ggggtattac 8940 catcagggag cggcttcaag cgaaggtgaa acaagtgcga caagcggcaa agtcgtgttg 9000 ttcttgcacg gttctggttc ttctgctgaa gagcaagcga gcgcgattcg caaccactac 9060 caaaaacaag gtatcgacat gctcgcagtc aacctgcgtg gctatggtga aagcgacggc 9120 ggaccaagcg aaaaaggctt gtaccaagac gctcgcacca tgttcaacta cctagtgaac 9180 gacaagggta ttgatccaag caatatcatc attcacggct actcaatggg tggtccaatt 9240 gccgcagatt tagcacgtta tgccgcgcaa aacggccaag cggtgtctgg cttattgctt 9300 gaccgtccta tgccaagcat gaccaaagcc atcaccgctc acgaaatggc gaatccagcg 9360 ggtattgtgg gggctatcgc gaaagcggtt aacggccaat tctcagtgga gaagaaccta 9420 aaaggcttgc caaaagagac gccgattctg ctgctaacgg acaacgaagg cttaggtgaa 9480 gaaggcgaga agctacgagc taaactcgcg attgctggct acaacgtcac gggtgaacaa 9540 accttctatg gccacgaagc gagcaaccgc ttgatgggtc agtacgcgga tcaaattgtc 9600 tccggtctgt tcaatgcaga gcaagcagcg gtagaagcgg gcgaagtgct gaaagggcta 9660 gagaaagact ttaaacgcta tggcgacgcg ctgaaaccag atacgagcgt accgggtaaa 9720 tcgaaagaca ttcgcaccac taaagatttc ctaaatggtt acaaaaacga tcatgcgaag 9780 gagatcgttg acggcttccg ctcagatatg agcatcaagc aactggtgga tctgtttgtt 9840 aaaggcaact ggagtgcaga gcaaaaaggt gcgcttgctt gggaaatcga aagtcgtgca 9900 ctgaaagtca cgttccagaa caagtctgag aagtacaacc gattgttccg tgagattgct 9960 tctgctggcg tggtggatgc gaaagcgact gaacagcttg cgccacagtt aatgctgttg 10020 aacctatcga atgacggttt tggtggacgt tgtgatccac tttctaaact cgttttggtt 10080 gctaaacagc ttgaaaacga tggtcaagtt ggcgtggcaa gacaactgct ggagaagatg 10140 tactctgcgg cagctgtgct gagcaatcca accctttact cagacagtga aaaagccaat 10200 gcaagcaagt tgctcagcag cttggcggcc attcatgcga agaacccaat gcatgatacg 10260 tcgatgaaag tgtggcagga aaagctggaa gggaagcaag cgctgaccgt aaacggtgtg 10320 gttgagaaaa tcactgatgc atcggctaac ggtaaacctg tgctgttgga acttgatgct 10380 ccggggcatg cgatggcagc ttgggcaaaa gactcaggcg acgatcgtgt ttacggcttc 10440 tacgatccaa atgctggcat tgttgagttc tcgtcggcag agaagtttgg cgactaccta 10500 acgcgtttct tcggcaagtc cgatctggac atggctcaaa gctataagct aggcaaaaac 10560 gacgcaggtg aagcaatctt caaccgcgtg gtggtaatgg atggcaacac gttagcaagc 10620 tacaagccga ccttcggtga taagaccacc atgcagggga tcctcgatct acctgtgttt 10680 gacgctacac cgattaaaaa gcctacgggt ggagtcgcga gcgatctcga agcattgggt 10740 gataaaacca aggtcgtggt cgatttagcg caaatcttta cggtgcaaga gctgaaagaa 10800 agagcaaaag tttttgctaa accgattggc gcatcctacc aaggtattct cgatcaactc 10860 gaccttgtgc atcaggctaa aggccgcgat caaatcgcag cgagctttga gcttaataag 10920 aagattaatg actacatcgc tgaacatcca acttcggggc gtaatcaagc gctaacgcag 10980 ttgaaagagc aggtcaccag tgcgttgttt atcggtaaga tgcaagttgc ccaagcgggt 11040 attgatgcaa tcgcacaaac aagaccggag cttgccgctc gtatctttat ggtcgcgatt 11100 gaagaagcca acggtaaaca cgtaggtttg acggacatga tggttcgttg ggccaatgaa 11160 gacccatact tggcaccgaa gcatggttac aaaggcgaaa cgccaagtga ccttggtttt 11220 gatgcgaagt accacgtaga tctaggtgag cattacgctg atttcaaaca gtggttagaa 11280 acgtcccagt cgaacgggtt gttgagtaaa gcgacgttgg atgaatccac taaaacggtt 11340 catcttggct atagctatca agaacttcag gatttgacgg gtgctgaatc ggtgcaaatg 11400 gcattctact tcctgaaaga agcggcgaag aaagcggatc cgatttctgg tgattcagct 11460 gaaatgatac tgctgaagaa atttgcagat caaagctact tatctcaact tgattccgac 11520 cgaatggatc aaattgaagg tatctaccgc agtagccatg agacggatat tgacgcttgg 11580 gatcgtcgtt actctggtac aggctatgat gagctgacga ataagcttgc tagcgcaacg 11640 ggcgttgacg agcagcttgc ggttcttctg gatgatcgta aaggcctctt gattggtgaa 11700 gtgcatggca gcgacgtcaa cggcctacgc tttgttaatg aacagatgga tgcactgaaa 11760 aaacagggag tcacagtcat tggccttgag catttacgct cagaccttgc gcaaccgctg 11820 attgatcgct acctagctac gggtgtgatg tcgagtgaac taagcgcaat gctgaaaaca 11880 aagcatctcg atgtcactct ttttgaaaac gcacgtgcta acggtatacg catcgtcgcg 11940 ctggatgcaa acagctctgc gcgtccaaat gttcagggaa cagaacatgg tctgatgtac 12000 cgtgctggtg ctgcgaacaa cattgcggtg gaagtattac aaaatctgcc tgatggcgaa 12060 aagttcgttg ctatctacgg taaagcgcat ttgcagtctc acaaagggat tgaagggttc 12120 gttcctggta tcacgcaccg cctcgatctt cctgcgctta aagtcagtga ctcgaaccag 12180 ttcacagttg aacaagacga tgtgagtcta cgtgttgtct acgatgatgt tgctaacaaa 12240 ccgaagatca cgttcaagga cagtttgagt ggcgcaaata ccgctcttca caaccaaaat 12300 gtgaatgact gggaacgtgt tgttgtgact ccgacagcgg acggcggtga aagccgtttt 12360 gatggtcaaa tcatcgtgca aatggagaac gatgatgtcg tggcaaaagc cgctgcgaac 12420 cttgcgggta agcacccaga aagcagtgtg gtggtgcaga tcgattcaga cggcaactat 12480 cgcgtggtgt atggcgatcc gtcaaagctg gatggaaagc tacgttggca gttagtaggt 12540 catggtcgag atgactcaga aagtaacaac acgcgtttaa gtggctacag tgccgatgag 12600 ctggcagtga aattggccaa gttccaacag tcgtttaatc aagcggaaaa catcaacaat 12660 aagcctgacc atatcagtat tgttggttgt tctttggtga gtgacgacaa gcaaaaaggc 12720 tttggtcatc agtttattaa cgcgatggat gcgaatggtc ttcgtgtcga tgtctctgta 12780 cgcagttctg aactggccgt agacgaggca gggcgtaaac ataccaagga cgcgaatggc 12840 gattgggtcc aaaaagccga aaacaacaaa gtttcgctaa gctgggacga gcaaggtgaa 12900 gttgttgcca aggatgaacg tattcgcaat ggtattgcgg aaggcgacat cgatctctct 12960 cgcattggtg tcagcgacgt tgacgagcca gctcgtggtg caatcggtga caacaatgat 13020 gtgtttgatg cgccagaaaa acgcaaagcg gagacagaaa cctcatcttc ttctgcaaac 13080 aataaactca gctactcagg taacattcaa gtcaatgtgg gtgatggtga gtttacggca 13140 gtgaactggg gcacatcgaa tgtgggcatt aaagtcggca cgggtggctt taagtcgctg 13200 gcctttggtg acaataacgt catggttcac atcggcaatg gtgagagcaa gcacagcttc 13260 gatattggtg gttatcaggc actggaaggt gcgcaaatgt tcatcggtaa tcgtaatgtg 13320 agcttcaact taggtcgaag taatgatctg attgtgatga tggacaagtc aattccgact 13380 ccgccattgg ttaatccgtt cgatggtgcc gctcgtattt cgggcgtact gcaaagcatt 13440 gccacctcgg gtgagggcca agattggcta gcggctcaag agcagcaatg gacattgtct 13500 ggcgccaaga agtttgtcaa agatatgtct ggtttggatc agagcagcag cgttgattac 13560 accagtttgg ttgaactaga ctcgcagaac gagcgaagca gccgtggctt gaagcacgat 13620 gcagaagcgg ctctgaacaa gcagtacaat caatggttaa gtggcaatag cgattctgac 13680 accagcaagc tcagccgcgc agataagctt cgtcaagcca atgaaaagct tgcgtttaac 13740 tttgccgtgg gtggtcaagg tgcggatatc caagtcacga caggtaactg gaacttcatg 13800 tttggtgaca acatccagtc tattttggat accaacctag gttcactgtt tggcctcatg 13860 acacagcagt tctctgctac gggtcaggcc aagacaacct tcacctacac gccagaagat 13920 ttgcctcgtc agcttaagaa caagctactt gggcagttag cgggtgtagg agccgagacc 13980 acgctagcgg atatttttgg tgtggattac accgcgtcag gtcaaattgt ttcgcgtaat 14040 ggtgaagctg tcgatggtgt agcgattctc aaagagatgt tggaggtcat tggtgagttc 14100 agtggtgatc aactgcaagc ctttgtcgac ccagctaagt tactggatag cttgaagtcg 14160 ggtatcaaca tgggtgcgga tggcattaag tcttttgctg aaactcatgg actgaaagag 14220 aaggcgccag aagaggaaga ggacaactct tcggtttctg ttaatggtgc gagcgtaaac 14280 agtgcgcaag gcgcgacggt ggctgatggc agcactgaaa cagcagaaac accagatcgt 14340 gcctttggct ttaactcgct taacctgccg aacttgttcg ccactatctt tagtcaagac 14400 aagcagaaag agatgaaatc gctggtggaa aatctcaaag agaatctcac cgctgatctg 14460 ctgaatatga aagagaaaac gtttgatttc cttcgtaaca gtggtcatct ccaaggtgat 14520 ggcgatatca acatctccct aggaaactac aacttcaact ggggtggcga tggtaaagat 14580 ctcggagcgt atctaggaga caacaacaac ttctggggcg gacgaggcga tgatgtgttc 14640 tacgcaacag gcacgtcaaa catcttcacg ggcggcgaag gcaacgacat gggcgttctg 14700 atgggacgtg aaaacatgat gtttggcggt gatggcaacg acacagcagt ggttgcagga 14760 cgcattaacc atgtcttcct tggtgccggt gatgaccagt cgtttgtctt tggtgagggc 14820 ggtgaaattg acaccggttc aggccgcgac tacgtggtga cgtctggcaa cttcaaccgt 14880 gtggatacgg gggatgatca agactactcc gttacgattg gcaacaacaa ccaagtagag 14940 ctaggcgctg gcaatgactt tgctaatgtc ttcggtaact acaaccgtat caatgcaagc 15000 gctggcaacg atgttgtgaa gctaatgggc tatcacgccg tgttgaatgg tggtgagggc 15060 gaggaccatc tcatcgcagc agccatctct aagttcagcc aattcaacgg tggcgaaggg 15120 cgcgatctga tggtgttggg tggttatcaa aacacgttca aaggtggcac ggatgtggac 15180 agctttgtgg tgagcggtga tgttatcgac aaccttgttg aagacattcg cagcgaagat 15240 aacattgtct tcaatggcat cgattggcag aaactgtggt tcgaacgcag cggatatgac 15300 ctgaagttgt ctattcttcg tgacccggca agtgacagtg accaagcgaa gtttgagcat 15360 attggttcgg tgacgttcag tgattacttt aacggtaatc gagcgcaggt gatcatcgca 15420 atgggtgaga aagacgcgac gggtgaacgt gagtacacca ccttgtctga gagtgcaatt 15480 gatgcgctgg tacaagccat gagtggcttt gaccctcagg cgggtgacaa tggattcatg 15540 gataacctag acagcaaatc tcgtgtggcg attaccactg cgtgggcaga cgttgtccat 15600 aaaaagggta taacggtgta a 15621 //