ID SIT99353; SV 1; linear; genomic DNA; STD; PRO; 546 BP. XX PA LT708304.1 XX PR Project:PRJEB15187; XX DT 19-JAN-2017 (Rel. 131, Created) DT 25-MAY-2020 (Rel. 144, Last updated, Version 6) XX DE Mycobacterium tuberculosis variant bovis AF2122/97 adenylate kinase adk DE (atp-amp transphosphorylase) XX KW . XX OS Mycobacterium tuberculosis variant bovis AF2122/97 OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; OC Mycobacterium; Mycobacterium tuberculosis complex. XX RN [1] RA Malone K.M.; RT ; RL Submitted (06-DEC-2016) to the INSDC. RL School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research RL Group, University College Dublin, Tuberculosis Molecular Microbiology RL Research Group, School of Veterinary Medicine, University College Dublin, RL D4, Ireland XX RN [2] RA Malone M K., Farrell D., Malone K.; RT ; RL Submitted (15-APR-2020) to the INSDC. RL School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research RL Group, University College Dublin, Tuberculosis Molecular Microbiology RL Research Group, School of Veterinary Medicine,, University College Dublin, RL D4, Ireland XX DR MD5; 1b68dafd3700dc2ea2c1a7e3dd811052. DR BioSample; SAMEA20450668. XX FH Key Location/Qualifiers FH FT source 1..546 FT /organism="Mycobacterium tuberculosis variant bovis FT AF2122/97" FT /chromosome="Mycobacterium_bovis_AF212297" FT /isolate="AF2122/97" FT /mol_type="genomic DNA" FT /isolation_source="Mycobacterium bovis subsp. bovis strain FT AF2122/97. This strain is a fully virulent strain that was FT isolated in 1997 in the UK from a cow suffering necrotic FT lesions in lung and bronchomediastinal lymph nodes. The FT strain was also reported to infect and persist in badgers FT that are considered to be a significant source of bovine FT infection." FT /db_xref="taxon:233413" FT CDS LT708304.1:827944..828489 FT /codon_start=1 FT /transl_table=11 FT /gene="adk" FT /locus_tag="BQ2027_MB0754" FT /product="adenylate kinase adk (atp-amp FT transphosphorylase)" FT /note="Mb0754, adk, len: 181 aa. Equivalent to Rv0733, len: FT 181 aa, from Mycobacterium tuberculosis strain H37Rv, FT (100.0% identity in 181 aa overlap). Probable adk, FT adenylate kinase (ATP-AMP transphosphorylase) (EC 2.7.4.3), FT equivalent to Z98756|MLCB24 92_28 probable adenylate kinase FT from Mycobacterium leprae (181 aa), FASTA scores: opt: 978, FT E(): 0, (83.6% identity in 177 aa overlap); and FT AAF86323.1|AF271342 putative adenylate kinase from FT Mycobacterium marinum (124 aa) (N-terminus shorter). Also FT highly similar to others e.g. P43414|KAD_STRCO ADENYLATE FT KINASE from Streptomyces coelicolor (217 aa), FASTA score: FT (43.0% identity in 186 aa overlap); etc. Contains PS00113 FT Adenylate kinase signature. BELONGS TO THE ADENYLATE KINASE FT FAMILY. Protein product from Mb0754 detected using shotgun FT mass spectrometry and SWATH mass spectrometry. Mb0754 found FT to be expressed during exponential growth in Sauton's FT minimal media by RNA-sequencing." FT /db_xref="GOA:P69439" FT /db_xref="InterPro:IPR000850" FT /db_xref="InterPro:IPR027417" FT /db_xref="InterPro:IPR033690" FT /db_xref="UniProtKB/Swiss-Prot:P69439" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="SIT99353.1" FT /translation="MRVLLLGPPGAGKGTQAVKLAEKLGIPQISTGELFRRNIEEGTKL FT GVEAKRYLDAGDLVPSDLTNELVDDRLNNPDAANGFILDGYPRSVEQAKALHEMLERRG FT TDIDAVLEFRVSEEVLLERLKGRGRADDTDDVILNRMKVYRDETAPLLEYYRDQLKTVD FT AVGTMDEVFARALRALGK" XX SQ Sequence 546 BP; 108 A; 160 C; 188 G; 90 T; 0 other; gtgagagttt tgttgctggg accgcccggg gcgggcaagg ggacgcaggc ggtgaagctc 60 gccgagaagc tcgggatccc gcagatctcc accggcgaac tcttccggcg caacatcgaa 120 gagggcacca agctcggcgt ggaagccaaa cgctacttgg atgccggtga cttggtgccg 180 tccgacttga ccaatgaact cgtcgacgac cggctgaaca atccggacgc ggccaacgga 240 ttcatcttgg atggctatcc acgctcggtc gagcaggcca aggcgcttca cgagatgctc 300 gaacgccggg ggaccgacat cgacgcggtg ctggagtttc gtgtgtccga ggaggtgttg 360 ttggagcgac tcaaggggcg tggccgcgcc gacgacaccg acgacgtcat cctcaaccgg 420 atgaaggtct accgcgacga gaccgcgccg ctgctggagt actaccgcga ccaattgaag 480 accgtcgacg ccgtcggcac catggacgag gtgttcgccc gtgcgttgcg ggctctggga 540 aagtag 546 //