Examples: histone, BN000065

Project: PRJEB71972

Using long-read nanopore sequencing, we obtained chromosome-wide phased methylomes of the active and inactive X in mouse placenta and neural stem cells (NSCs), overcoming the limitations if short-read bisulfite sequencing in allelic resolution. We also conducted quantitative analysis of methylation properties like symmetry and entropy, providing a more comprehensive view of epigenetic silencing in X chromosome inactivation. We also resolved the allele-specific genetics and epigenetics of structural macrosatellite Dxz4 and other repeats.

Secondary Study Accession:
ERP156758
Study Title:
Whole-chromosome methylation patterns of the mouse inactive X
Center Name:
European Bioinformatics Institute;Epigenetics and Development Division;The Walter and Eliza Hall Institute of Medical Research
Study Name:
Whole-chromosome methylation patterns of the mouse inactive X
Broker Name:
ArrayExpress
ENA-FIRST-PUBLIC:
2024-03-12
ENA-LAST-UPDATE:
2024-03-12
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