Leishmania tropica is one of the causative agents of cutaneous leishmaniasis. Approximately 12 million people worldwide are affected by leishmaniasis, and more than 350 million people live in at-risk areas. Indeed, Leishmania species infections, which are primarily transmitted by the bite of infected sand flies, produce a substantial burden of disease in more than 88 countries worldwide. L tropica is associated with Old World cutaneous disease in urban areas of the Middle East and cities in the Mediterranean area, India, and Pakistan.