In order to elucidate the general rules for gene localization and regulation mediated by CpG islands, we reanalyzed diverse published data of DNaseI-seq, MeDIP-seq, LMNB1-DamID-seq, PolII ChIA-pet, and Hi-C analysis. Overall design: DNaseI-seq, MeDIP-seq, LMNB1-DamID-seq, PolII ChIA-pet, and Hi-C analysis