The aim of this research was to explore activation/deactivation of signaling pathways in neuroblastoma samples Overall design: Neural crest cells were used as a control for transcriptome analysis of neuroblastoma samples. Adrenal glands were taken from aborted fetuses after 25 weeks of gestation. Samples were formalin-fixed and paraffin-embedded. Tissues were examined by histologist to confirm presence of neuroblasts.