Mediterranean mussel is an important aquacultured species which live in a close contact with numerous marine microorganisms. As all invertebrates, they lack an adaptive immune response but it has been reported that invertebrates may respond to an infection involving a high degree of pathogen specificity and innate immune memory or “priming”.

In this work we conducted Illumina sequencing of the mussel hemocytes transcriptome stimulated in vitro: triplicates of pools of 25 individuals after 8 hours of stimulation. About 70 million raw reads were obtained from each sample, which were assembled into more than 200,000 contigs.

the goal of this experiment is to provide new insights into the innate immune memory or priming in Mytilus galloprovincialis, and its possible aplication in aquaculture.