To investigate new health functions by blackcurrant extract (BCE), we compare altered of the genes expression before and after BCE (2.0μg/ml) treatment in Human Umbilical Vein Endothelial Cells (HUVEC). Overall design: HUVEC were seeded in culture dish and maintain to confluent. Then medium replace with phenol red-free follicle dermal papilla cell basal medium with or without BCE (2.0μg/ml). After the cells were incubated for 24 h at 37 °C 5% CO2.