In our study, we valided the important oncogeneic roles of KIMAT1 and HIF1A-As2 in non-small cell lung cancer. We used custom designed GapmeRs to silence the KIMAT1 and HIF1A-As2 in H1299 and performed small RNA-seq. 214 and 233 microRNAs were regulated by KIMAT1 and HIF1A-As2, respectively. Overall design: GapmeRs targeting control or lncRNAs were tranfected in H1299 cells. Total RNAs were extracted after 48 hours of tranfection.