Y37A1B.5, a SELENBP1 ortholog in C. elegans modulates lifespan and stress resistance. Hence transcriptome profiling (RNA-seq) after depletion of Y37A1B.5 via RNAi was performed, aiming to identify targets that would explain these effects. Overall design: We compared RNAi treatment of Y37A1B.5 for five days to control vector treatment for five days in wildtype worms.