Project: PRJNA554832
We performed a cytoscanHD array to analyze copy number variations in the genome of 33 human pleural mesothelioma cell lines established from patient pleural effusion. We were particularly interested in the analysis of the p21.3 region of chromosome 9 which contains CDKN2A tumor suppressor genes and the gene encoding type I interferons that are often deleted and confer sensitivity to oncolytic Measles virus Overall design: Copy number analysis of Affymetrix CytoscanHD arrays was performed for 33 human pleural mesothelioma cell lines