Examples: histone, BN000065

Project: PRJNA589614

The aim of presented study was to assess the relationship between the presence of estrogen receptor and WWOX gene in breast cancer cell lines. Overall design: The study was based on estrogen-responsive (MCF7) and estrogen-unresponsive (MDA-MB-231, BT20) cell lines, for which depending on native expression, WWOX gene was either induced by retroviral transfection (MDA-MB-231) or silenced with shRNA (MCF7, BT20), and changes in the phenotype were estrogen stimulated. We have employed nAnT-iCAGE methodology for high-throughput gene expression profiling.

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