to screen upregulated lincRNAs in pressure overloaded hearts, we conducted microarray analysis Overall design: To identify transcribed intergenic regions that yield upregulated lincRNAs during cardiac remodeling, we performed a screen using total RNA extracted from mouse hearts subjected to transverse aortic constriction (TAC) surgery. In this screen, we assessed two time points at 2 weeks and 8 weeks after TAC surgery for the hypertrophic response and the heart failure phase, respectively.