GWAS Catalog

PubMed ID

19578366

First author

Wrensch M

Journal

Nat Genet

Publication date

2009-07-05

Title

Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.

Authors

Wrensch M, Jenkins RB, Chang JS, Yeh RF, Xiao Y, Decker PA, Ballman KV

, Berger M, Buckner JC, Chang S, Giannini C, Halder C, Kollmeyer TM, Kosel ML, LaChance DH, McCoy L, O'Neill BP, Patoka J, Pico AR...

, Prados M, Quesenberry C, Rice T, Rynearson AL, Smirnov I, Tihan T, Wiemels J, Yang P, Wiencke JK Show more >

Full Summary Statistics

Not available

Show entries

Variant and risk allele	P-value	P-value annotation	RAF	OR	Beta	CI	Mapped gene	Reported trait	Trait(s)	Background trait(s)	Study accession	Location

rs6010620-G	3 x 10^-9	-	0.77	1.52	-	[1.32-1.75]	RTEL1-TNFRSF6B, RTEL1	Glioma (high-grade)	central nervous system cancer	-	GCST000440	20:63678486
rs1412829-C	2 x 10^-10	-	0.39	1.42	-	[1.27-1.58]	CDKN2B-AS1	Glioma (high-grade)	central nervous system cancer	-	GCST000440	9:22043927
rs4809324-C	2 x 10^-9	-	0.10	1.6	-	[1.37-1.87]	RTEL1-TNFRSF6B, RTEL1	Glioma (high-grade)	central nervous system cancer	-	GCST000440	20:63686867

Showing 1 to 3 of 3 entries

Publication: Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.

First author	Study accession	Pub. date	Journal	Title	Reported trait	Trait(s)	Background trait(s)	Discovery sample number	Replication sample number	Association count	Summary statistics

Wrensch M	GCST000440	2009-07-05	Nat Genet	Variants in the CDKN2B and RTEL1 regions are…	Glioma (high-grade)	central nervous system cancer	-	• 4684 European	• 174 African American or Afro-Caribbean, European, Hispanic or Latin American, Asian unspecified, Native American, Other • 2 Other • 174 European	3	Not available