Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
RNA-Seq mRNA differential
Organism:
Mus musculus
Publication:
- Belmont PJ, Jiang P, McKee TD, Xie T, Isaacson J et al. (2014) Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.
Genes
ENSMUSG00000109145✖
Log2-fold change
Adjusted p-value
Comparisons
Selected: 2 / 2
Showing 1 gene:
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Log2-fold change
-2.6
0