-9.9 | | Fap | 'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-9.6 | | Fap | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-5.8 | | Fap | 'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
5.6 | | Fap | 'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
5.4 | | Fap | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
-4.8 | | Fap | '70 week' vs '6 week' in 'none; none; | age, irradiate | Pericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence |
-4.8 | | Fap | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
4.4 | | Fap | 'Duchenne muscular dystrophy' vs 'normal' | disease | RNA-seq comparison of immortalised myoblasts from dystrophic and WT mice |
-4.3 | | Fap | 'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
4 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
4 | | Fap | 'MEF; transduced with NeuroD2 lentivirus' vs 'MEF; control' | cell line, treatment | Genetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling] |
-3.9 | | Fap | 'acute myeloid leukemia' vs 'myeloproliferative disorder' | disease | Transcription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm |
-3.8 | | Fap | 'Zbtb10 knockdown' vs 'control' at '6 hour' | genotype, time | RNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+) |
3.7 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
3.7 | | Fap | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
-3.7 | | Fap | 'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
3.6 | | Fap | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
3.5 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
3.5 | | Fap | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-3.5 | | Fap | 'carcinoma' vs 'normal' | disease | Gene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse |
3.4 | | Fap | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
3.4 | | Fap | 'carotid body' vs 'adrenal medulla' | organism part | Expression profile of mouse carotid body and adrenal medulla [RNA-Seq] |
3.4 | | Fap | '3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
3.3 | | Fap | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
3.2 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
3.2 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
3.1 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
3.1 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-3.1 | | Fap | 'adipogenic' vs 'non-adipogenic' | phenotype | Transcription profiling by array of mouse sublines of Swiss 3T3 fibroblasts with varying potential for adipogenesis |
3.1 | | Fap | '9 day' vs '0 day' | time | Transcription profiling by array of mineralising murine vascular smooth muscle cell cultures over a nine day culture period to identify new regulators of vascular mineralization |
3 | | Fap | 'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
-3 | | Fap | 'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'neutrophil' | cell type, genotype | RNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice |
3 | | Fap | 'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
3 | | Fap | 'SMRT shRNA' vs 'none' in 'none' at '0 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
2.9 | | Fap | 'osteoblast culture 27 day' vs '0 day' | time | Transcription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation |
2.9 | | Fap | 'SMRT shRNA' vs 'none' in 'CpG' at '6 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
2.8 | | Fap | 'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2.7 | | Fap | 'osteoblast culture 9 day' vs '0 day' | time | Transcription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation |
2.7 | | Fap | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
2.7 | | Fap | 'Helicobacter hepaticus' vs 'none' in 'wild type phenotype' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
2.7 | | Fap | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar and interferon beta; 100 units per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.6 | | Fap | 'mutant MyoD expression' at '24 hour' vs 'wild type MyoD expression' at '0 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
2.6 | | Fap | 'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
2.5 | | Fap | 'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
2.5 | | Fap | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-2.5 | | Fap | 'acute graft vs. host disease' vs 'normal' | compound, disease | Transcription profiling by array of murine thymus medulla in the absence and presence of acute graft-versus-host disease |
2.5 | | Fap | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.5 | | Fap | 'CpG; 6 hour' vs 'none; 0 hour' in 'SMRT shRNA' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
2.4 | | Fap | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
2.4 | | Fap | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-2.4 | | Fap | 'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week' | age, genotype | Prevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA |
2.4 | | Fap | '12 week' vs '4 week' | age | Differential gene expression in the Lacrimal gland during development and onset of xerostomia in Sjogren's syndrome-like disease of the C57BL/6.NOD-Aec1Aec2 mouse. |
-2.4 | | Fap | 'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
2.4 | | Fap | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
2.3 | | Fap | 'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
2.3 | | Fap | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.3 | | Fap | '8 week' vs '4 week' | age | Differential gene expression in the Lacrimal gland during development and onset of xerostomia in Sjogren's syndrome-like disease of the C57BL/6.NOD-Aec1Aec2 mouse. |
-2.3 | | Fap | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
2.3 | | Fap | 'PTEN null, P53-/-' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
-2.3 | | Fap | "muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP positive" | organism part, phenotype | Bulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages |
2.2 | | Fap | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-2.2 | | Fap | 'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
2.2 | | Fap | 'mutant MyoD expression' at '24 hour' vs 'control' at '24 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
2.2 | | Fap | 'SARS coronavirus MA15' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
2.2 | | Fap | 'infarct and border region of left ventricle 5 days post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; MRL/MpJ' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
2.2 | | Fap | 'CD2314' vs 'none' at '11 day' | age, compound | Transcription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors |
-2.2 | | Fap | '14M1.4; Leishmania donovani infected' at '48 hour' vs '14M1.4; normal' at '48 hour' | cell line, infect, time | Transcription profiling of 3 mouse cell lines infected with Leishmania |
-2.1 | | Fap | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
2.1 | | Fap | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2.1 | | Fap | 'chronic pancreatitis' vs 'control' | disease | Pancreatic gene expression associated with cerulein induced chronic pancreatitis in mice |
2.1 | | Fap | '6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
2.1 | | Fap | 'cardiotoxin; 40 microliter' vs 'none' in 'wild type' at '12 day' | compound, genotype, time | Transcription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin |
2.1 | | Fap | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
2.1 | | Fap | 'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-2.1 | | Fap | 'total RNA; HRasV12 and c-Myc overexpression and Eif4e wild type' vs 'total RNA; wild type' | fraction, genotype | Redefining the role of eIF4E dose in development, cancer, and protein synthesis |
2.1 | | Fap | 'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
2.1 | | Fap | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
2 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2 | | Fap | 'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
2 | | Fap | '16 week' vs '4 week' | age | Differential gene expression in the Lacrimal gland during development and onset of xerostomia in Sjogren's syndrome-like disease of the C57BL/6.NOD-Aec1Aec2 mouse. |
2 | | Fap | 'unilateral ureteral obstruction' vs 'sham' in 'wild type' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
2 | | Fap | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
1.9 | | Fap | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
1.9 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.9 | | Fap | 'non-infarct region of left ventricle 5 days post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as non-infarct tissue in post-myocardial infarction hearts; MRL/MpJ' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
-1.9 | | Fap | 'postnatal day 21; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-1.9 | | Fap | 'oral hard palate epithelium' vs 'tail skin epithelium' | organism part | Transcriptional profiling of mouse oral and skin epithelium to study their intrinsic difference in global gene expression |
-1.9 | | Fap | '30 month' vs '5 month' in 'male' | age, block, sex | Expression data from tail skin in young (5 months) and old (30 months) CB6F1 mice |
1.8 | | Fap | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.8 | | Fap | 'postnatal >1 year; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-1.8 | | Fap | '19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day' | cell line, growth condition, time | Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines |
1.8 | | Fap | 'CKIαΔgut/p53R172H' vs 'CKIαΔgut/p53Δgut' in 'jejunum' | compound, genotype, organism part | RNAseq of enterocytes of the jejunum and Ileum from transgene C57BL/6 mice harboring a CKIαΔgut knock-out |
1.7 | | Fap | 'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '2 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
1.7 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.7 | | Fap | 'SARS coronavirus MA15' vs 'none' at '2 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
1.7 | | Fap | 'infarct and border region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
1.7 | | Fap | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
1.7 | | Fap | 'unilateral ureteral obstruction' vs 'sham' in 'TIMP2 -/-' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
1.7 | | Fap | 'Foxd3 knockout' vs 'control' | phenotype | Expression data from embryonic stem cells differentiation |
1.7 | | Fap | 'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1.7 | | Fap | 'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector' | genotype | RNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice |
1.7 | | Fap | 'Trp53 Arg178Asp' vs 'wild type genotype' in 'Nutlin-3a; 10 micromolar' | compound, phenotype | Residual tumor suppressor activities of tumorigenic p53 mutants enhance survival under chemotherapy |
-1.7 | | Fap | 'Macrophage of F4/80+, CD11b+, CD11c-; obese leptin-deficient' vs 'Macrophage of F4/80+, CD11b+, CD11c-; control' | cell type, genotype | Expression data from mouse adipose tissue macrophage |
1.7 | | Fap | 'Hnf1a knock out' vs 'wild type' | genotype | Transcription profiling of pancreatic islets from Hnf1a-deficient and wild type mice |
-1.6 | | Fap | 'Psen 1 and 2 null' vs 'wild type' | genotype | Quantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS |
1.6 | | Fap | 'wild type; SARS MA15; 2 day' vs 'wild type; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
-1.6 | | Fap | 'none; XPF knockout' vs 'all-trans-retinoic acid; 10 micromolar; wild type genotype' | compound, genotype | RNA-seq of mouse DNA repair endonuclease XPF knock out versus wild type and versus trans retinoic acid (tRA) treated wild type |
1.6 | | Fap | 'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
1.6 | | Fap | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
1.6 | | Fap | 'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal' | disease | Transcription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma |
1.6 | | Fap | 'interferon beta' vs 'none' in 'wild type; uninfected' | compound, disease, genotype | Transcription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN |
-1.6 | | Fap | 'CpG ODN' vs 'PBS' at '24 hour' | compound, time | Transcription profiling by array of mouse vaginal samples following adjuvant treatment |
-1.6 | | Fap | 'side population cells' vs 'main population cells' in 'muscle' | cell type, organism part | Gene expression of side population and main population cells, isolated from adult murine skeletal muscle and bone marrow |
-1.6 | | Fap | 'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell' | age, cell type, phenotype | Transcription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture |
1.6 | | Fap | 'Irx3 knockout' vs 'control' at '1 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
1.6 | | Fap | 'Trp53 knockout' vs 'wild type genotype' in 'Nutlin-3a; 10 micromolar' | compound, phenotype | Residual tumor suppressor activities of tumorigenic p53 mutants enhance survival under chemotherapy |
1.6 | | Fap | 'dominant-negative Brg1' vs 'wild type' | genotype | Transcription profiling by array of lens tissue from mice expressing a dnBrg1 transgenic construct |
-1.5 | | Fap | 'RBPjk null' vs 'wild type' | genotype | Quantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS |
1.5 | | Fap | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.5 | | Fap | '3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
1.5 | | Fap | 'SARS coronavirus MA15 dORF6' vs 'none' at '2 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
1.5 | | Fap | 'MEF; transduced with MyoD lentivirus' vs 'MEF; control' | cell line, treatment | Genetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling] |
-1.5 | | Fap | 'acute oropharyngeal candidiasis' vs 'healthy' in wild type mice | compound, disease, genotype, sex | Transcription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis |
1.5 | | Fap | 'heart-specific Mdm2 knockout; 14 day' vs 'heart-specific Mdm2 knockout; 7 day' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
-1.5 | | Fap | 'bronchoalveolar adenocarcinoma induced using doxycycline' vs 'normal' | disease | Transcription profiling by array of lung alveolar type II epithelial cells with bronchoalveolar adenocarcinoma |
-1.5 | | Fap | 'acute oropharyngeal candidiasis wild type mice'; female' vs 'healthy wild type genotype mice' | compound, disease, genotype, sex | Transcription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis |
1.5 | | Fap | 'SARS coronavirus MA15' vs 'none' at '1 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
1.5 | | Fap | '10 day' vs '0 day' | age | Time course analysis of the cardiac transcriptome in the neonatal period |
1.5 | | Fap | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.5 | | Fap | 'epithelial cell; E2' vs 'epithelial cell; vehicle' | cell type, treatment | Affymetrix gene chip analysis for the whole mouse genome transcripts of epithelial and stromal cells from mouse uterine primary co-culture treated with either vehicle or E2 |
1.5 | | Fap | 'Plasmodium chabaudi infection' vs 'no infection' in 'adjuvant only' | infect, treatment | Protective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase |
1.5 | | Fap | 'Adipo-H363Y' vs 'wild type genotype' in 'Ad libitum; 40 week' | age, diet, genotype | Gene expression analysis of adipose tissues from WT, Adipo-SIRT1 and Adipo-H363Y mice |
-1.5 | | Fap | 'total RNA; HRasV12 and c-Myc overexpression and Eif4e heterozygous knockout' vs 'total RNA; wild type' | fraction, genotype | Redefining the role of eIF4E dose in development, cancer, and protein synthesis |
1.5 | | Fap | 'Smad4f/f x CCSPicrePtenf/f' vs 'wild type' at '12 month' | age, genotype | ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [expression] |
1.5 | | Fap | 'Trp53 knockout' vs 'wild type genotype' in 'dimethyl sulfoxide; 0.1 microliter' | compound, phenotype | Residual tumor suppressor activities of tumorigenic p53 mutants enhance survival under chemotherapy |
-1.4 | | Fap | 'Notch 1 and 2 null' vs 'wild type' | genotype | Quantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS |
1.4 | | Fap | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.4 | | Fap | 'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '2 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
1.4 | | Fap | '3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
1.4 | | Fap | 'embryonic day 16.5' vs 'embryonic day 11.5' | developmental stage | Gene expression profile of diaphragm morphogenesis at different developmental stages |
1.4 | | Fap | 'SARS coronavirus MA15' vs 'none' at '2 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-1.4 | | Fap | 'primary hair placode keratinocyte' vs 'interfollicular epidermal keratinocyte' | cell type | Transcription profiling of mouse primary hair placode keratinocytes compared to interfollicular epidermal keratinocytes |
-1.4 | | Fap | 'Rb1 mutant' vs 'wild type' | genotype | A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene targeted mice |
1.4 | | Fap | 'polarized with E coli lipopolysacharide and INF-gamma' vs 'untreated' | compound, treatment | Expression data from polarized macrophages: effect of p53 |
1.4 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.4 | | Fap | 'H9; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day' | cell line, growth condition, time | Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines |
-1.3 | | Fap | 'brown adipose tissue' vs 'white adipose tissue' in 'high fat diet; 30 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1.3 | | Fap | 'SARS coronavirus MA15; 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.3 | | Fap | 'mutant (Pdgfc-/-; Pdgfra GFP/+)' vs 'control' | genotype | Cerebral gene expression changes in Pdgfc and Pdgfra mutant |
1.3 | | Fap | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.3 | | Fap | 'heart-specific p53 and Mdm2 knockout; 7 day' vs 'heart-specific p53 and Mdm2 knockout; 1 day' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
1.3 | | Fap | '2 day' vs '1 day' in 'influenza A infected DBA/2J' | disease, strain, time | Transcription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection |
-1.3 | | Fap | 'uterine-specific Tsc2-null' vs 'wild type' in 'oopherectomized' | genotype, treatment | Transcription profiling by high throughput sequencing of uterine-specific Tsc2-null mice |
-1.3 | | Fap | 'lipid nanoparticle complexed with ribonucleic acid expressing respiratory synctial virus F protein' vs 'phosphate buffered saline' | stimulus | Microarray analysis of mouse whole genome using self-amplifying messenger (SAM) RNA delivered with different formulations compared to controls |
-1.3 | | Fap | 'Adjuvant System 03' vs 'PBS' in 'hindlimb muscle' at '6 hour' | organism part, stimulus, time | Expression data from draining lymph node and muscle of mice immunised with AS03 or PBS |
1.3 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NZO/HILtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.2 | | Fap | 'mdx/mdx' vs 'wild type' | genotype | Transcription profiling by array of mdx mouse gastrocnemius muscle |
1.2 | | Fap | 'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'C57BL/6J' | infect, strain, time | Gene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans |
-1.2 | | Fap | Synacthen vs sodium chloride control | compound | Transcription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses. |
1.2 | | Fap | 'macrophage; lipopolysaccharide stimulated' vs 'macrophage; unstimulated' | cell type, treatment | Gene expression profile of GM-CSF derived bone marrow dendritic cell subsets after LPS stimulation |
1.2 | | Fap | 'Influenza A virus' vs 'mock' in 'IgG1' | infect, stimulus | Transcription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza |
1.2 | | Fap | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.2 | | Fap | 'conditional UPF2 knockout; before partial hepatechtomy' vs 'control; before partial hepatechtomy' | genotype, sampling time | Transcription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy |
1.2 | | Fap | 'InsR, Igf1R double knockout' vs 'wild type' in 'postnatal day 5' | developmental stage, genotype | Transcriptional profiling by array of mouse wild-type and Insulin receptor (InsR)/Igf1 receptor (Igf1R) double knockout mutant Sertoli cells from testis at embryonic day E17.5 and Postnatal day 5 |
1.2 | | Fap | 'all-trans-retinoic acid; 10 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq of mouse DNA repair endonuclease XPF knock out versus wild type and versus trans retinoic acid (tRA) treated wild type |
1.2 | | Fap | "YFP positive" vs "YFP negative" in "lamina propria of small intestine" | organism part, phenotype | Bulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages |
1.2 | | Fap | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.2 | | Fap | 'H9; undifferentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; undifferentiated embryonic stem cell' at '0 day' | cell line, growth condition, time | Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines |
1.2 | | Fap | 'cardiotoxin; 40 microliter' vs 'none' in 'MLC-CnAb1 overexpression' at '12 day' | compound, genotype, time | Transcription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin |
-1.1 | | Fap | 'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
1.1 | | Fap | '6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
-1.1 | | Fap | 'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
1.1 | | Fap | '3 day' vs '1 day' in 'influenza A infected DBA/2J' | disease, strain, time | Transcription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection |
1.1 | | Fap | 'high fat diet' vs 'normal' | diet | Gene expression changes in Ahnak knockout mice |
1.1 | | Fap | 'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'Nfkbiz-/-' | compound, genotype | Inhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2) |
-1.1 | | Fap | 'SARS coronavirus MA15 dORF6' vs 'SARS coronavirus MA15' at '1 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
-1.1 | | Fap | 'APP/APLP2 double conditional knockout' vs 'control' | genotype | Transcriptional Profiling of Neuronal APP/APLP2 Double-Conditional Knockout Mice. |
1.1 | | Fap | 'Adipo-SIRT1' vs 'wild type genotype' in 'Ad libitum; 40 week' | age, diet, genotype | Gene expression analysis of adipose tissues from WT, Adipo-SIRT1 and Adipo-H363Y mice |
1.1 | | Fap | 'SARS coronavirus MA15 E protein mutant Δ3' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
-1.1 | | Fap | 'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells' | age, cell type | Transcriptional profiling of nascent and mature pancreatic beta cells |
1.1 | | Fap | 'SARS coronavirus MA15 E protein mutant Δ5' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
-1 | | Fap | 'Fgf10 -/-' vs 'wild type genotype' in 'none' | genotype, stimulus | Role of Fgf10 signalling in regulation of gene expression in developing mouse cortex |
1 | | Fap | 'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '2 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-1 | | Fap | 'Adjuvant System 03' vs 'PBS' in 'lymph node' at '6 hour' | organism part, stimulus, time | Expression data from draining lymph node and muscle of mice immunised with AS03 or PBS |
-1 | | Fap | 'CpG ODN' vs 'PBS' at '48 hour' | compound, time | Transcription profiling by array of mouse vaginal samples following adjuvant treatment |
-1 | | Fap | 'inhibition of BRD4 with JQ1' vs 'DMSO' | treatment | Expression Data For BRD4 Inhibition |
1 | | Fap | 'Influenza A virus' vs 'mock' in 'interleukin-22' | infect, stimulus | Transcription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza |
-1 | | Fap | 'heart-specific Mdm2 knockout; 7 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
1 | | Fap | 'Crx knockout' vs 'control' at '6 zeitgeber' | genotype, time | Transcriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20 |
-1 | | Fap | '5-aza-2'-deoxycytidine; 5 micromolar' vs 'none' | compound | Transcription profiling by array of mouse primary dermal fibroblasts after treatment with 5-aza-2'-deoxycytidine |
1 | | Fap | 'mutant MyoD expression' at '6 hour' vs 'control' at '6 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
-1 | | Fap | 'heart-specific p53 and Mdm2 knockout; 1 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
-1 | | Fap | 'Cdx2 knockdown' vs 'scramble shRNA' in 'induced hepatocyte' | cell type, genotype | Dissecting engineered cell types and enhancing cell fate conversion via CellNet |
1 | | Fap | '5 day' vs '0 day' | age | Time course analysis of the cardiac transcriptome in the neonatal period |
-1 | | Fap | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
1 | | Fap | 'influenza' vs 'uninfected' in 'wild type' | compound, disease, genotype | Transcription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN |
1 | | Fap | 'transplanted secondary tumors' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |