ENSMUSG00000021208 (Ifi27l2b)

mus musculus

interferon, alpha-inducible protein 27 like 2B

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Mus musculus
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Showing 56 experiments:
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Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermhippocampuslungolfactory bulbskeletal muscle organtracheaaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartintestinal mucosalateral prominence neural epitheliummedial nasal prominencemuscle (biceps femoris)oviductpreoptic areaspleensubventricular zonevesicular glandwhole organism
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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14 - embryonic day 10.5
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 13
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Mammalian Kaessmann
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GENCODE
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Vertebrates
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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Developing gut
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49 FANTOM5 project - embryonic day 11
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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3 Soumillon et al
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Sun et al., 2020 - Organism part
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4 Bonthuis et al - C57BL/6J
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Fat and muscle
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - lactating adult …
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Huttlin et al., 2010 - tissues - brain, …
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Linscheid et al., 2021 - tissue - heart …
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Duda et al., 2018 - organism part - …
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Linscheid et al. 2019 - organism part
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Deshmukh et al., 2015 - organism part
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Zhao et al., 2019 - tissue - lens
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Meierhofer et al., 2016 - organism part
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
7.7667 × 10-45-7.3
Ifi27l2b"muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP negative"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
1.2051 × 10-15-7.2
Ifi27l2b"muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP positive"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
2.6763 × 10-37.1
Ifi27l2b'19 to 22 month' vs '3 to 4 month' in 'endothelial cell'age, cell typeRNA-seq of 5 populations from the regenerative region of the brain of young and old mice
Adjusted p-valueLog2-fold change
2.538 × 10-186.9
Ifi27l2b'PTEN null' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.9291 × 10-105.9
Ifi27l2b'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
3.1122 × 10-33.8
Ifi27l2b'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
3.6097 × 10-93.3
Ifi27l2b'H-Ras expression; c-Myc activation' vs 'wild type'phenotypeRNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls.
Adjusted p-valueLog2-fold change
1.668 × 10-6-3.1
Ifi27l2b'pkd1 knockout' vs 'wild type' in 'presence of fluid flow'genotype, stimulusTranscription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow
Adjusted p-valueLog2-fold change
1.1666 × 10-83
Ifi27l2b'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
4.896 × 10-63
Ifi27l2b'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
1.3007 × 10-5-3
Ifi27l2b'missense mutation (T2996C) in Mucin 2 (Muc2)' vs 'wild type genotype'genotypeTranscription profiling of mouse intestine in ENU mutagenesis mouse strains with missense mutations in Muc2 mucin and ER stress
Adjusted p-valueLog2-fold change
3.9415 × 10-432.9
Ifi27l2b'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
3.2275 × 10-52.9
Ifi27l2b'SARS coronavirus MA15' vs 'none' at '4 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
3.9935 × 10-272.8
Ifi27l2b'liver-specific Cnot1 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
5.3054 × 10-82.8
Ifi27l2b'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
6.7249 × 10-82.8
Ifi27l2b'confluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.1303 × 10-52.8
Ifi27l2b'high fat diet' vs 'regular chow diet' in 'wild type genotype'diet, genotypeTranscription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
Adjusted p-valueLog2-fold change
7.6173 × 10-42.8
Ifi27l2b'Rb^{lox/lox}; p130^{lox/lox}; p107+/-' vs 'wild type'genotypeTranscription profiling by array of livers from the mouse model of human hepatocellular carcinoma
Adjusted p-valueLog2-fold change
1.7349 × 10-32.8
Ifi27l2b'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
1.9287 × 10-62.7
Ifi27l2b'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
3.9366 × 10-62.7
Ifi27l2b'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
4.1329 × 10-62.7
Ifi27l2b'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '2 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
4.1128 × 10-52.7
Ifi27l2b'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
6.9599 × 10-52.7
Ifi27l2b'lung carcinoma' vs 'normal' in 'lung cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
9.0403 × 10-92.6
Ifi27l2b'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
1.3519 × 10-72.6
Ifi27l2b'CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
6.7617 × 10-72.6
Ifi27l2b'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.3568 × 10-72.6
Ifi27l2b'antibiotics, CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
1.5843 × 10-62.6
Ifi27l2b'SARS coronavirus MA15' vs 'none' at '2 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
1.63 × 10-42.6
Ifi27l2b'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.2783 × 10-2-2.6
Ifi27l2b'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.6246 × 10-22.6
Ifi27l2b'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
2.0734 × 10-1152.5
Ifi27l2b'interleukin-28A; 1000 nanogram per milliliter' vs 'none'compoundTranscription profiling by high throughput sequencing of murine small intestinal epithelial cells stimulated with interleukin-28A
Adjusted p-valueLog2-fold change
1.157 × 10-52.4
Ifi27l2b'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
4.204 × 10-42.4
Ifi27l2b'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
2.6125 × 10-32.4
Ifi27l2b'SARS coronavirus MA15' vs 'none' at '4 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
1.0311 × 10-2-2.4
Ifi27l2b'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue'organism part, phenotypeRNA-seq to identify the role of mRNA decay in mouse adipose tissues
Adjusted p-valueLog2-fold change
3.9203 × 10-82.3
Ifi27l2b'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
5.7416 × 10-6-2.3
Ifi27l2b'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.7456 × 10-4-2.3
Ifi27l2b'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
8.0547 × 10-3-2.3
Ifi27l2b'uterine-specific Tsc2-null' vs 'wild type' in '17beta-estradiol'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
2.8526 × 10-15-2.2
Ifi27l2b'high fat' vs 'chow' in 'WSB/EiJ'diet, strainTranscription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ
Adjusted p-valueLog2-fold change
4.8513 × 10-122.2
Ifi27l2b'wild type; SARS MA15; 2 day' vs 'wild type; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
2.0394 × 10-72.2
Ifi27l2b'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.6089 × 10-62.2
Ifi27l2b'SARS coronavirus MA15' vs 'none' at '2 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
1.3603 × 10-42.2
Ifi27l2b'SARS coronavirus MA15 dORF6' vs 'none' at '4 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
1.8072 × 10-32.2
Ifi27l2b'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
4.1725 × 10-2-2.2
Ifi27l2b'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
8.4065 × 10-62.1
Ifi27l2b'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock'genotype, infect, timeSARS infection of C57BL6, and PLAT knock-out mice
Adjusted p-valueLog2-fold change
6.4242 × 10-42.1
Ifi27l2b'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '4 day'genotype, infect, timeSM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice
Adjusted p-valueLog2-fold change
7.5392 × 10-43-2
Ifi27l2b'interferon gamma; 10 nanogram per milliliter and interleukin-22; 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
1.2796 × 10-92
Ifi27l2b'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '2 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
9.4618 × 10-7-2
Ifi27l2b'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
1.1483 × 10-62
Ifi27l2b'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
4.4649 × 10-62
Ifi27l2b'AKR/J mice co-housed 1:1 with C57BL/6 mice' vs 'AKR/J mice in single housing'growth conditionGut microbiota and gallstone formation - cohousing study
Adjusted p-valueLog2-fold change
6.9594 × 10-62
Ifi27l2b'Ercc1 knock out' vs 'wild type'genotypeTranscription profiling by array of liver from mice mutant for Ercc1
Adjusted p-valueLog2-fold change
3.4399 × 10-52
Ifi27l2b'SARS coronavirus MA15' vs 'none' in 'Tnfrsf1a/1b -/-' at '4 day'genotype, infect, timeSM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice
Adjusted p-valueLog2-fold change
9.6946 × 10-5-2
Ifi27l2b'pkd1 knockout' vs 'wild type' in 'absence of fluid flow'genotype, stimulusTranscription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow
Adjusted p-valueLog2-fold change
4.1245 × 10-42
Ifi27l2b'Taf10-/-' vs 'wild type'genotypeTranscription profiling by array of liver from Taf10 knock out mice
Adjusted p-valueLog2-fold change
2.537 × 10-22
Ifi27l2b'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.9325 × 10-91.9
Ifi27l2b'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '2 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
4.2352 × 10-51.9
Ifi27l2b'TIMP1 knockout; SARS MA15; 4 day' vs 'TIMP1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
2.5149 × 10-41.9
Ifi27l2b'PAI1 knockout; SARS MA15; 4 day' vs 'PAI1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
4.0988 × 10-4-1.9
Ifi27l2b'liver-specific Pit1 knockout' vs 'wild type genotype' in 'high fat diet'diet, genotypeTranscription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
Adjusted p-valueLog2-fold change
5.6721 × 10-41.9
Ifi27l2b'liver specific SMARCB1 knockout' vs 'wild type'phenotypeTP53 is a master regulator of proteostasis in SMARCB1-deficient malignant rhabdoid tumors
Adjusted p-valueLog2-fold change
1.0543 × 10-21.9
Ifi27l2b'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '4 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
2.074 × 10-21.9
Ifi27l2b'SARS coronavirus MA15' vs 'none' in 'IFNAR1 -/-' at '5 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds
Adjusted p-valueLog2-fold change
3.6225 × 10-2-1.9
Ifi27l2b'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
1.955 × 10-51.8
Ifi27l2b'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '4 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
1.2843 × 10-31.8
Ifi27l2b'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
6.308 × 10-131.7
Ifi27l2b'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.5975 × 10-101.7
Ifi27l2b'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
3.3427 × 10-61.7
Ifi27l2b'confluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
6.2479 × 10-61.7
Ifi27l2b'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
7.1852 × 10-61.7
Ifi27l2b'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.8513 × 10-41.7
Ifi27l2b'SARS coronavirus MA15' vs 'none' at '7 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
5.3787 × 10-3-1.7
Ifi27l2b'AhCre Apc Floxed Cited1 knockout' vs 'control'genotypeCited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis
Adjusted p-valueLog2-fold change
1.0808 × 10-21.7
Ifi27l2b'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.4676 × 10-26-1.6
Ifi27l2b'interleukin-22 (Mus Musculus); 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
3.8933 × 10-61.6
Ifi27l2b'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
5.96 × 10-51.6
Ifi27l2b'CCl4; 1.6 gram per kilogram' at '48 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
1.1042 × 10-41.6
Ifi27l2b'SARS coronavirus MA15 dORF6' vs 'none' at '2 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
6.868 × 10-4-1.6
Ifi27l2b'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
1.3961 × 10-31.6
Ifi27l2b'atherogenic rodent' vs 'control'dietLiver mRNA microarray study for mice treated with various diets
Adjusted p-valueLog2-fold change
2.071 × 10-21.6
Ifi27l2b'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
6.5491 × 10-10-1.5
Ifi27l2b'epithelium-specific Apc knockout' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
6.9608 × 10-81.5
Ifi27l2b'180 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
7.7669 × 10-81.5
Ifi27l2b'5-aza-2'-deoxycytidine; 5 micromolar' vs 'none'compoundTranscription profiling by array of mouse primary dermal fibroblasts after treatment with 5-aza-2'-deoxycytidine
Adjusted p-valueLog2-fold change
9.4458 × 10-71.5
Ifi27l2b'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.0132 × 10-51.5
Ifi27l2b'collagen sandwich' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.0691 × 10-51.5
Ifi27l2b'confluent monolayer on collagen' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.9649 × 10-51.5
Ifi27l2b'methionine- and choline-deficient, high fat diet mixed with 0.1% metformin' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
1.7105 × 10-2-1.5
Ifi27l2b'dextran sodium sulphate induced colitis' at '7 day' vs 'normal' at '0 day'disease, timeTranscription profiling by array of Mus musculus colonic mucosa after treatment with dextran sodium sulphate (DSS) for 2 or 7 days which induces experimental colitis
Adjusted p-valueLog2-fold change
2.5354 × 10-2-1.5
Ifi27l2b'Fhl1 knockdown by siRNA' vs 'wild type' at '1 day'phenotype, time3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1
Adjusted p-valueLog2-fold change
1.0202 × 10-18-1.4
Ifi27l2b'epithelium-specific mutant beta-catenin expression' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
1.3267 × 10-71.4
Ifi27l2b'90 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
5.7297 × 10-71.4
Ifi27l2b'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
8.3441 × 10-61.4
Ifi27l2b'Western diet' vs 'control diet'diettranscription profiling by array of C57BL/6J mice fed a Western-style diet with or without 0.05% quercetin against mice on a control diet to study the effect of quercetin on obesity and hepatic gene expression
Adjusted p-valueLog2-fold change
1.5672 × 10-21.4
Ifi27l2b'SERF2-/-' vs 'SERF2+/+'genotypeRNA-seq of mouse embryonic fibroblasts(MEFs) with knock-out of SERF2 compared to control MEFs
Adjusted p-valueLog2-fold change
1.9469 × 10-21.4
Ifi27l2b'130 week' vs '13 week' in 'liver'age, organism partTranscription profiling by array of liver, lung, spleen and kidney from young and old mice.
Adjusted p-valueLog2-fold change
4.5838 × 10-21.4
Ifi27l2b'interferon gamma' vs 'dexamethasone; 100 nanomolar'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
1.0356 × 10-91.3
Ifi27l2b'wild type genotype; SARS MA15; 7 day' vs 'wild type genotype; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
3.2862 × 10-81.3
Ifi27l2b'Gucy2c S839I mutant' vs 'wild type genotype'genotypeTranscriptomic analysis of the distal colon of wild type C57BL/6N mice and mice harboring a mutation (S839I) in Gucy2c
Adjusted p-valueLog2-fold change
9.5376 × 10-81.3
Ifi27l2b'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '4 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
1.6974 × 10-71.3
Ifi27l2b'365 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.6777 × 10-51.3
Ifi27l2b'Western diet with 0.05% quercetin' vs 'control diet'diettranscription profiling by array of C57BL/6J mice fed a Western-style diet with or without 0.05% quercetin against mice on a control diet to study the effect of quercetin on obesity and hepatic gene expression
Adjusted p-valueLog2-fold change
1.7429 × 10-51.3
Ifi27l2b'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.8658 × 10-51.3
Ifi27l2b'methionine- and choline-deficient, high fat diet' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
1.0742 × 10-3-1.3
Ifi27l2b'ticagrelor; 180 milligram per kilogram per day' vs 'none'compoundRNA-Seq of the liver of hypercholesterolemic mice treated by either ticagrelor, clopidogrel, or control.
Adjusted p-valueLog2-fold change
2.6834 × 10-31.3
Ifi27l2b'Iodoform; 93 milligram per kilogram; corn oil' vs 'none; ; corn oil'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
3.4524 × 10-31.3
Ifi27l2b'SARS coronavirus MA15 lacking full-length E protein' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
5.0202 × 10-31.3
Ifi27l2b"YFP positive" vs "YFP negative" in "lamina propria of small intestine"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
4.4668 × 10-16-1.2
Ifi27l2b'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
2.563 × 10-15-1.2
Ifi27l2b'interferon gamma; 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
7.5812 × 10-71.2
Ifi27l2b'30 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.253 × 10-61.2
Ifi27l2b'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
5.9262 × 10-51.2
Ifi27l2b'PAI1 knockout; SARS MA15; 7 day' vs 'PAI1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
1.5749 × 10-41.2
Ifi27l2b'TIMP1 knockout; SARS MA15; 7 day' vs 'TIMP1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
3.5149 × 10-41.2
Ifi27l2b'SARS coronavirus MA15' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
1.3129 × 10-31.2
Ifi27l2b'Plasmodium berghei ANKA' at '7 day' vs 'none' at '0 day' in 'none'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
4.0881 × 10-31.2
Ifi27l2b'transgenic hepatic growth hormone and hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '12 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
4.7357 × 10-3-1.2
Ifi27l2b'STAT1 -/-' vs 'wild type genotype' in 'SARS coronavirus MA15' at '2 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds
Adjusted p-valueLog2-fold change
4.8068 × 10-31.2
Ifi27l2b'high fat diet' vs 'regular chow diet' in 'liver-specific Pit1 knockout'diet, genotypeTranscription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
Adjusted p-valueLog2-fold change
2.8889 × 10-2-1.2
Ifi27l2b'10 month' vs '2 month'ageRNA-seq of adipocyte progenitor cells derived from old and young mice to investigate the molecular signature of aging
Adjusted p-valueLog2-fold change
4.33 × 10-41.1
Ifi27l2b'control; streptozotocin-induced diabetes' vs 'control; control'diet, phenotypeHepatic gene expression in streptozotocin-induced diabetic mice fed a phloridzin diet
Adjusted p-valueLog2-fold change
8.3167 × 10-41.1
Ifi27l2b'SARS coronavirus MA15 E protein mutant Δ3' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
9.7903 × 10-41.1
Ifi27l2b'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '7 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
4.4649 × 10-3-1.1
Ifi27l2b'Fn14 knockout' vs 'wild type' in 'none'compound, genotypeChronic TNBS Colitis in the FN14 KO Mouse
Adjusted p-valueLog2-fold change
4.9711 × 10-3-1.1
Ifi27l2b'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '30 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
1.0911 × 10-21.1
Ifi27l2b'transgenic hepatic growth hormone and hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '40 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
1.3221 × 10-2-1.1
Ifi27l2b'eIF6+/-' vs 'wild type genotype'genotypeRNA-seq of liver biopsies of eIF6 wild type and eIF6 heterozygous mice
Adjusted p-valueLog2-fold change
1.6071 × 10-21.1
Ifi27l2b'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type'genotypeHepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice
Adjusted p-valueLog2-fold change
1.9643 × 10-21.1
Ifi27l2b'Alb-Cre;VHLf/f' vs 'Alb-Cre'genotypeTranscription profiling by array of mice with liver-specific expression of hypoxia inducible factor, or inactivated von Hippel-Lindau tumor suppressor
Adjusted p-valueLog2-fold change
2.0577 × 10-11-1
Ifi27l2b'organoid culture without Noggin (ER medium)' vs 'organoid culture (ENR medium)' in 'none'growth condition, stimulusRNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant
Adjusted p-valueLog2-fold change
1.0114 × 10-91
Ifi27l2b'intestinal smooth muscle culture supernatant' vs 'none' in 'organoid culture without Noggin (ER medium)'growth condition, stimulusRNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant
Adjusted p-valueLog2-fold change
6.9975 × 10-6-1
Ifi27l2b'intermittent fasting every 24 hours' vs 'ad libitum'dietGenome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver
Adjusted p-valueLog2-fold change
1.5718 × 10-41
Ifi27l2b'CCl4; 1.6 gram per kilogram' at '96 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
4.2448 × 10-41
Ifi27l2b'Pten knockout' vs 'wild type' at '15 month'genotype, timeTranscription profiling by array of Pten knockout liver cells of mouse
Adjusted p-valueLog2-fold change
3.7151 × 10-31
Ifi27l2b'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
4.6452 × 10-31
Ifi27l2b'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day'genotype, infect, timeSM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice
Adjusted p-valueLog2-fold change
5.1543 × 10-31
Ifi27l2b'control; 36 hour after partial hepatechtomy' vs 'control; before partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
7.2026 × 10-3-1
Ifi27l2b'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '14 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
7.2575 × 10-3-1
Ifi27l2b'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '10 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
9.5376 × 10-31
Ifi27l2b'hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '12 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
1.3309 × 10-2-1
Ifi27l2b'IEC-specific HDAC3 deletion' vs 'floxed HDAC3 (wild type)'genotypeTranscription profiling by array of intestinal epithelial cells (IECs) from mice with IEC-specific HDAC3 deletion against wild type controls
Adjusted p-valueLog2-fold change
1.4227 × 10-2-1
Ifi27l2b'6 month; RXRa hepatic deficiency; male' vs '6 month; wild type; male'age, genotype, sexTranscription profiling of liver from wild type and RXR-alpha deficient matured and aged mcie
Adjusted p-valueLog2-fold change
2.3186 × 10-2-1
Ifi27l2b'IFNR null' vs 'wild type' in 'influenza infected'compound, disease, genotypeTranscription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN
Adjusted p-valueLog2-fold change
3.262 × 10-21
Ifi27l2b'LKB1 knockout; floxed LKB1 with RIP-Cre' vs 'floxed LKB1 without RIP-Cre; wild type'genotype, phenotypeTranscription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice
Adjusted p-valueLog2-fold change
3.3656 × 10-2-1
Ifi27l2b'AhCre Apc Floxed' vs 'control'genotypeCited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis
Adjusted p-valueLog2-fold change
4.545 × 10-2-1
Ifi27l2b'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Synonym
1810023F06Rik
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
A_55_P2085779, 17283556, A_55_P2085776, 4598413, 10402353, 4328598, 4752391, ILMN_1232995, 165944_at, 1425120_x_at, 4580560, 5206198, A_51_P391432, 5100005, 4737929