ENSMUSG00000022215 (Fitm1)

mus musculus

fat storage-inducing transmembrane protein 1

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Mus musculus
Organism part
Showing 56 experiments:
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Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermhippocampuslungolfactory bulbskeletal muscle organtracheaaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartintestinal mucosalateral prominence neural epitheliummedial nasal prominencemuscle (biceps femoris)oviductpreoptic areaspleensubventricular zonevesicular glandwhole organism
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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9
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14 - embryonic day 10.5
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 13
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Mammalian Kaessmann
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GENCODE
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Vertebrates
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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Developing gut
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49 FANTOM5 project - embryonic day 11
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3
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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3 Soumillon et al
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Sun et al., 2020 - Organism part
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4 Bonthuis et al - C57BL/6J
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Fat and muscle
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - lactating adult …
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Huttlin et al., 2010 - tissues - brain, …
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Linscheid et al., 2021 - tissue - heart …
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Duda et al., 2018 - organism part - …
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Duda et al., 2018 - organism part - …
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Linscheid et al. 2019 - organism part
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Deshmukh et al., 2015 - organism part
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Zhao et al., 2019 - tissue - lens
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Meierhofer et al., 2016 - organism part
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Proteomics
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Transcriptomics
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Kingdom
Species
Experiment type
Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
2.1848 × 10-7-7.9
Fitm1'70 week' vs '6 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
2.5996 × 10-87.8
Fitm1'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
1.3668 × 10-6-5.1
Fitm1'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.7928 × 10-6-4.7
Fitm1'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
5.7138 × 10-5-4.5
Fitm1'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
6.2012 × 10-5-4.3
Fitm1'synovial sarcoma' vs 'normal'diseaseTranscription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice
Adjusted p-valueLog2-fold change
1.8652 × 10-6-4.2
Fitm1'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
7.2461 × 10-7-3.8
Fitm1'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal'diseaseTranscription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma
Adjusted p-valueLog2-fold change
3.8315 × 10-14-3.6
Fitm1'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
4.6247 × 10-4-3.3
Fitm1'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
1.2622 × 10-72.9
Fitm1'embryonic day 16.5' vs 'embryonic day 11.5'developmental stageGene expression profile of diaphragm morphogenesis at different developmental stages
Adjusted p-valueLog2-fold change
1.8808 × 10-4-2.9
Fitm1'transgenic hepatic growth hormone' vs 'wild type genotype' in '12 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
2.7476 × 10-5-2.6
Fitm1'no limb muscle' vs 'wild type'phenotypeTranscription profiling by array of TS23 humerus tissue from muscle-less mutant (splotch-delayed) mice and control littermates to identify differentially expressed genes between muscle-less and control embryonic (TS23) humerus tissue, in order to determine mechanosensitive genes that impact skeletal development
Adjusted p-valueLog2-fold change
9.8755 × 10-5-2.6
Fitm1'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
1.4184 × 10-22.6
Fitm1'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
3.6254 × 10-4-2.5
Fitm1'ko cyld-/-' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Cyld inactivation
Adjusted p-valueLog2-fold change
6.6356 × 10-4-2.5
Fitm1'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
1.2558 × 10-2-2.5
Fitm1'liver specific SMARCB1 knockout' vs 'wild type'phenotypeTP53 is a master regulator of proteostasis in SMARCB1-deficient malignant rhabdoid tumors
Adjusted p-valueLog2-fold change
1.6565 × 10-9-2.4
Fitm1'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
5.6507 × 10-52.4
Fitm1'db/db' vs 'wild type genotype' in 'control miRNA; fasted'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
3.5432 × 10-32.4
Fitm1'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.6516 × 10-7-2.3
Fitm1'carcinoma' vs 'normal'diseaseGene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse
Adjusted p-valueLog2-fold change
3.1962 × 10-4-2.3
Fitm1'tumor' vs 'normal' in 'liver'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
6.7984 × 10-4-2.3
Fitm1'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
2.1432 × 10-52.2
Fitm1'Fxr -/-' vs 'wild type'diet, genotype, pregnancyTranscription profiling by array of mouse liver from control, pregnant, cholate fed mice and Frx null mice
Adjusted p-valueLog2-fold change
1.6303 × 10-4-2.2
Fitm1'6 month; RXRa hepatic deficiency; male' vs '6 month; wild type; male'age, genotype, sexTranscription profiling of liver from wild type and RXR-alpha deficient matured and aged mcie
Adjusted p-valueLog2-fold change
1.1049 × 10-10-2.1
Fitm1'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
9.3952 × 10-102.1
Fitm1'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
3.4339 × 10-5-2.1
Fitm1'liver-specific Cnot1 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
4.6294 × 10-4-2.1
Fitm1'streptozotocin' vs 'mock'treatmentLiver adapts mitochondrial function to insulin-resistant and diabetic states in mice
Adjusted p-valueLog2-fold change
4.9125 × 10-52
Fitm1'Gabpa miRNA' vs 'control miRNA' in 'wild type genotype; fasted'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
2.3983 × 10-2-2
Fitm1'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week'age, genotypePrevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA
Adjusted p-valueLog2-fold change
1.284 × 10-10-1.9
Fitm1'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
1.8586 × 10-21.9
Fitm1'365 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
7.4746 × 10-101.8
Fitm1'1,4-Dichlorobenzene; 600 milligram per kilogram; corn oil' vs 'none; ; corn oil'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
5.0343 × 10-91.8
Fitm1'1,4-Dichlorobenzene; 500 milligram per kilogram; corn oil' vs 'none; ; corn oil'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
6.5251 × 10-51.8
Fitm1'Pten knockout' vs 'wild type' at '3 month'genotype, timeTranscription profiling by array of Pten knockout liver cells of mouse
Adjusted p-valueLog2-fold change
1.0567 × 10-4-1.8
Fitm1'heart-specific p53 and Mdm2 knockout; 7 day' vs 'heart-specific p53 and Mdm2 knockout; 1 day'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
1.6658 × 10-21.8
Fitm1'hepatocyte-specific Pten knockout' vs 'wild type'genotypeHepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice
Adjusted p-valueLog2-fold change
1.755 × 10-2-1.8
Fitm1'8 week; Str/ort' vs '8 week; CBA'age, strainExpression data of cartiliage from CBA and STR/ORT mice
Adjusted p-valueLog2-fold change
8.0112 × 10-151.7
Fitm1'high fat' vs 'chow' in '129S1/SvImJ'diet, strainTranscription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ
Adjusted p-valueLog2-fold change
7.5558 × 10-101.7
Fitm1'reduced expression of miR-25' vs 'wild type'phenotypeTranscription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice
Adjusted p-valueLog2-fold change
8.5882 × 10-61.7
Fitm1'1,5-Naphthalenediamine; 2000 part per million; rodent chow' vs 'none; ; rodent chow'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
1.8646 × 10-5-1.7
Fitm1'methionine- and choline-deficient, high fat diet mixed with 0.1% metformin' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
8.4798 × 10-3-1.7
Fitm1'infarct and border region of left ventricle 5 days post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; MRL/MpJ'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
9.509 × 10-3-1.7
Fitm1'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.5491 × 10-21.7
Fitm1'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type'genotypeHepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice
Adjusted p-valueLog2-fold change
1.8067 × 10-21.7
Fitm1'acute myeloid leukemia' vs 'myeloproliferative disorder'diseaseTranscription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm
Adjusted p-valueLog2-fold change
3.1128 × 10-6-1.6
Fitm1'cardiac-specific constitutive expression of an activated Akt (caAkt)' vs 'wild type genotype'genotypeTranscription profiling by array of cardic ventricle tissues from mice with cardiac-specific constitutive expression of an activated Akt (caAkt) and wild-type controls to test whether Akt activation contributes to mitochondrial dysfunction in pathological cardiac hypertrophy
Adjusted p-valueLog2-fold change
8.1273 × 10-4-1.6
Fitm1'infarct and border region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
1.2361 × 10-91.5
Fitm1'high fat' vs 'chow' in 'NZO/HILtJ'diet, strainTranscription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ
Adjusted p-valueLog2-fold change
5.886 × 10-5-1.5
Fitm1'heterozygous RYR1 mutant' vs 'RYR1 wild type' in 'embryonic day 14.5'developmental stage, genotypeMicroarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels
Adjusted p-valueLog2-fold change
7.7607 × 10-41.5
Fitm1'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.1964 × 10-3-1.5
Fitm1'Rb^{lox/lox}; p130^{lox/lox}; p107+/-' vs 'wild type'genotypeTranscription profiling by array of livers from the mouse model of human hepatocellular carcinoma
Adjusted p-valueLog2-fold change
2.0171 × 10-31.5
Fitm1'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
1.6538 × 10-2-1.5
Fitm1'unilateral ureteral obstruction' vs 'sham' in 'wild type'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
4.5429 × 10-21.5
Fitm1'14 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
5.8722 × 10-131.4
Fitm1'high fat' vs 'chow' in 'WSB/EiJ'diet, strainTranscription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ
Adjusted p-valueLog2-fold change
6.0945 × 10-8-1.4
Fitm1'Reverbαflox/floxAlbCreERT2+' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
6.3183 × 10-6-1.4
Fitm1'Soulatrolide; 20 milligram per kilogram per day' vs 'control; 'compoundToxicogenomics on mice liver of coumarins from Calophyllum brasiliense
Adjusted p-valueLog2-fold change
3.7206 × 10-51.4
Fitm1'Gabpa miRNA' vs 'control miRNA' in 'wild type genotype; re-fed'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
9.6474 × 10-5-1.4
Fitm1'homozygous RYR1 mutant' vs 'RYR1 wild type' in 'embryonic day 14.5'developmental stage, genotypeMicroarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels
Adjusted p-valueLog2-fold change
7.0322 × 10-4-1.4
Fitm1'L-Pex5 knock-out' vs 'wild type'genotypeTranscription profiling by array of liver from L-Pex5 knock-out mice
Adjusted p-valueLog2-fold change
1.4379 × 10-3-1.4
Fitm1'unilateral ureteral obstruction' vs 'sham' in 'TIMP2 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
2.1509 × 10-3-1.4
Fitm1'diet restriction' vs 'control'dietLiver mRNA microarray study for mice treated with various diets
Adjusted p-valueLog2-fold change
2.1996 × 10-31.4
Fitm1'db/db' vs 'wild type genotype' in 'control miRNA; re-fed'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
3.3689 × 10-21.4
Fitm1'11beta-HSD knockout' vs 'wild type' in 'subcutaneous adipose tissue'genotype, organism partTranscription profiling of adipose tissue from mesenteric and subcutaneous depots from 11beta-HSD1 knockout and wild type mice
Adjusted p-valueLog2-fold change
4.3174 × 10-21.4
Fitm1'180 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
2.1944 × 10-61.3
Fitm1'high fat' vs 'chow' in 'C57BL/6J'diet, strainTranscription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ
Adjusted p-valueLog2-fold change
4.867 × 10-6-1.3
Fitm1'3110043O21Rik knockout; liver' vs 'wild type genotype; liver'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
2.201 × 10-4-1.3
Fitm1'Lmna G609G/G609G knock in' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Lmna Gly609Gly knock in
Adjusted p-valueLog2-fold change
1.1078 × 10-31.3
Fitm1'Adrb1, Adrb2 and Adrb3 knockout' vs 'wild type genotype' in '20 to 22 degree celsius'genotype, temperatureRNA-seq of cold-induced transcriptome changes in subcutaneous adipose tissue of beta-adrenergic receptor knockout mice
Adjusted p-valueLog2-fold change
3.6826 × 10-31.3
Fitm1'miR-1-133a_OSMR_tKO' vs 'miR-1-133a_dKO'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
2.6506 × 10-6-1.2
Fitm1'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.5622 × 10-4-1.2
Fitm1'CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
8.4944 × 10-31.2
Fitm1'Tris(2,3-dibromopropyl)phosphate; 1000 part per million; rodent chow' vs 'none; ; rodent chow'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
1.0301 × 10-21.2
Fitm1'high fat' vs 'control'dietLiver mRNA microarray study for mice treated with various diets
Adjusted p-valueLog2-fold change
1.1552 × 10-2-1.2
Fitm1'heart-specific p53 and Mdm2 knockout; 7 day' vs 'wild type phenotype'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
3.4971 × 10-21.2
Fitm1'P19; transduced with MyoD lentivirus' vs 'P19; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
8.9176 × 10-71.1
Fitm1'1,4-Dichlorobenzene; 400 milligram per kilogram; corn oil' vs 'none; ; corn oil'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
1.1523 × 10-51.1
Fitm1'1,4-Dichlorobenzene; 300 milligram per kilogram; corn oil' vs 'none; ; corn oil'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
8.576 × 10-5-1.1
Fitm1'TUT4 deficiency; TUT7 knockout' vs 'wild type'phenotypeMicroarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7
Adjusted p-valueLog2-fold change
9.6199 × 10-5-1.1
Fitm1'intermittent fasting every 16 hours' vs 'ad libitum'dietGenome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver
Adjusted p-valueLog2-fold change
2.8744 × 10-41.1
Fitm1'db/db' vs 'wild type genotype' in 'Gabpa miRNA; fasted'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
8.9592 × 10-41.1
Fitm1'high fat diet' vs 'regular chow diet' in 'wild type genotype'diet, genotypeTranscription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
Adjusted p-valueLog2-fold change
1.3843 × 10-31.1
Fitm1'4-Nitroanthranilic acid; 10000 part per million; rodent chow' vs 'none; ; rodent chow'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
2.7056 × 10-3-1.1
Fitm1'heart-specific Mdm2 knockout; 14 day' vs 'heart-specific Mdm2 knockout; 7 day'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
7.5824 × 10-31.1
Fitm1'1-Amino-2,4-dibromoanthraquinone; 20000 part per million; rodent chow' vs 'none; ; rodent chow'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
9.5723 × 10-31.1
Fitm1'high fat diet' vs 'control'dietTranscription profiling by array of liver from mice fed a high fat diet
Adjusted p-valueLog2-fold change
2.0523 × 10-2-1.1
Fitm1'KLF15 null' vs 'wild type genotype' in 'liver'genotype, organism partTranscription profiling of mouse livers and quadriceps muscles of Kruppel-like factor 15 (KLF15) null mutants after an overnight fast to provide insight into the role of KLF15 in gluconeogenesis
Adjusted p-valueLog2-fold change
2.2222 × 10-2-1.1
Fitm1'YAP S127A' vs 'Empty vector' at '48 hour'genotype, timeTranscription profiling by array of mouse primary myoblasts constitutively expressing Hippo pathway downstream effectors Yap or Taz against empty vector controls
Adjusted p-valueLog2-fold change
1.162 × 10-12-1
Fitm1'S-(1,2-dichlorovinyl)-L-cysteine; 15 milligram per kilogram; renal injury; 1 week' vs 'none; normal'compound, disease, timeExpression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC
Adjusted p-valueLog2-fold change
2.1157 × 10-81
Fitm1'fenofibrate diet' vs 'control diet'dietComparative transcriptomics and metabolomic analysis of fenofibrate and fish oil treatments in mice
Adjusted p-valueLog2-fold change
9.4561 × 10-6-1
Fitm1'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.5949 × 10-4-1
Fitm1'Sik1 knockout; liver' vs 'wild type genotype; liver'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
4.578 × 10-4-1
Fitm1'CCl4; 1.6 gram per kilogram' at '48 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
6.1669 × 10-4-1
Fitm1'Tbx5;Nkx2-5 knockout' vs 'wild type'genotypeTranscription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse
Adjusted p-valueLog2-fold change
9.3101 × 10-4-1
Fitm1'acute oropharyngeal candidiasis wild type mice'; female' vs 'healthy wild type genotype mice'compound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
1.0795 × 10-3-1
Fitm1'antibiotics, CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
2.1357 × 10-3-1
Fitm1'methionine- and choline-deficient, high fat diet' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
5.0472 × 10-3-1
Fitm1'Hepatic RXR_alpha-Knockout' vs 'wild type' in 'control'genotype, treatmentGene expression data of untreated and RA-treated wild type and RXRα-deficient mice liver
Adjusted p-valueLog2-fold change
1.0307 × 10-2-1
Fitm1'miR-1-133a_dKO' vs 'wild type genotype'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
2.9072 × 10-2-1
Fitm1'atherogenic rodent' vs 'control'dietLiver mRNA microarray study for mice treated with various diets
Adjusted p-valueLog2-fold change
4.9218 × 10-2-1
Fitm1'Reg3beta knockout' vs 'wild type' in 'tissue from infarction zone'clinical information, genotypemyocardial infarction in Reg3beta knock-out mice