-7.9 | | Fitm1 | '70 week' vs '6 week' in 'none; none; | age, irradiate | Pericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence |
7.8 | | Fitm1 | 'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
-5.1 | | Fitm1 | 'clear cell sarcoma; Rosa26CreER' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-4.7 | | Fitm1 | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-4.5 | | Fitm1 | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-4.3 | | Fitm1 | 'synovial sarcoma' vs 'normal' | disease | Transcription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice |
-4.2 | | Fitm1 | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
-3.8 | | Fitm1 | 'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal' | disease | Transcription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma |
-3.6 | | Fitm1 | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-3.3 | | Fitm1 | 'transplanted secondary tumors' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
2.9 | | Fitm1 | 'embryonic day 16.5' vs 'embryonic day 11.5' | developmental stage | Gene expression profile of diaphragm morphogenesis at different developmental stages |
-2.9 | | Fitm1 | 'transgenic hepatic growth hormone' vs 'wild type genotype' in '12 week' | age, genotype | Hepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice |
-2.6 | | Fitm1 | 'no limb muscle' vs 'wild type' | phenotype | Transcription profiling by array of TS23 humerus tissue from muscle-less mutant (splotch-delayed) mice and control littermates to identify differentially expressed genes between muscle-less and control embryonic (TS23) humerus tissue, in order to determine mechanosensitive genes that impact skeletal development |
-2.6 | | Fitm1 | 'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
2.6 | | Fitm1 | 'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell' | age, cell type, phenotype | Transcription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture |
-2.5 | | Fitm1 | 'ko cyld-/-' vs 'wild type' | genotype | Transcription profiling by array of mouse liver with Cyld inactivation |
-2.5 | | Fitm1 | 'Irx3 knockout' vs 'control' at '7 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
-2.5 | | Fitm1 | 'liver specific SMARCB1 knockout' vs 'wild type' | phenotype | TP53 is a master regulator of proteostasis in SMARCB1-deficient malignant rhabdoid tumors |
-2.4 | | Fitm1 | 'liver-specific Cnot3 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
2.4 | | Fitm1 | 'db/db' vs 'wild type genotype' in 'control miRNA; fasted' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
2.4 | | Fitm1 | '730 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-2.3 | | Fitm1 | 'carcinoma' vs 'normal' | disease | Gene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse |
-2.3 | | Fitm1 | 'tumor' vs 'normal' in 'liver' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
-2.3 | | Fitm1 | 'tumor' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
2.2 | | Fitm1 | 'Fxr -/-' vs 'wild type' | diet, genotype, pregnancy | Transcription profiling by array of mouse liver from control, pregnant, cholate fed mice and Frx null mice |
-2.2 | | Fitm1 | '6 month; RXRa hepatic deficiency; male' vs '6 month; wild type; male' | age, genotype, sex | Transcription profiling of liver from wild type and RXR-alpha deficient matured and aged mcie |
-2.1 | | Fitm1 | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
2.1 | | Fitm1 | 'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-2.1 | | Fitm1 | 'liver-specific Cnot1 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
-2.1 | | Fitm1 | 'streptozotocin' vs 'mock' | treatment | Liver adapts mitochondrial function to insulin-resistant and diabetic states in mice |
2 | | Fitm1 | 'Gabpa miRNA' vs 'control miRNA' in 'wild type genotype; fasted' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
-2 | | Fitm1 | 'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week' | age, genotype | Prevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA |
-1.9 | | Fitm1 | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
1.9 | | Fitm1 | '365 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
1.8 | | Fitm1 | '1,4-Dichlorobenzene; 600 milligram per kilogram; corn oil' vs 'none; ; corn oil' | compound, treatment | Transcription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals |
1.8 | | Fitm1 | '1,4-Dichlorobenzene; 500 milligram per kilogram; corn oil' vs 'none; ; corn oil' | compound, treatment | Transcription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals |
1.8 | | Fitm1 | 'Pten knockout' vs 'wild type' at '3 month' | genotype, time | Transcription profiling by array of Pten knockout liver cells of mouse |
-1.8 | | Fitm1 | 'heart-specific p53 and Mdm2 knockout; 7 day' vs 'heart-specific p53 and Mdm2 knockout; 1 day' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
1.8 | | Fitm1 | 'hepatocyte-specific Pten knockout' vs 'wild type' | genotype | Hepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice |
-1.8 | | Fitm1 | '8 week; Str/ort' vs '8 week; CBA' | age, strain | Expression data of cartiliage from CBA and STR/ORT mice |
1.7 | | Fitm1 | 'high fat' vs 'chow' in '129S1/SvImJ' | diet, strain | Transcription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ |
1.7 | | Fitm1 | 'reduced expression of miR-25' vs 'wild type' | phenotype | Transcription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice |
1.7 | | Fitm1 | '1,5-Naphthalenediamine; 2000 part per million; rodent chow' vs 'none; ; rodent chow' | compound, treatment | Transcription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals |
-1.7 | | Fitm1 | 'methionine- and choline-deficient, high fat diet mixed with 0.1% metformin' vs 'normal' | diet | Expression data from mouse liver treated with metformin |
-1.7 | | Fitm1 | 'infarct and border region of left ventricle 5 days post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; MRL/MpJ' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
-1.7 | | Fitm1 | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
1.7 | | Fitm1 | 'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type' | genotype | Hepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice |
1.7 | | Fitm1 | 'acute myeloid leukemia' vs 'myeloproliferative disorder' | disease | Transcription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm |
-1.6 | | Fitm1 | 'cardiac-specific constitutive expression of an activated Akt (caAkt)' vs 'wild type genotype' | genotype | Transcription profiling by array of cardic ventricle tissues from mice with cardiac-specific constitutive expression of an activated Akt (caAkt) and wild-type controls to test whether Akt activation contributes to mitochondrial dysfunction in pathological cardiac hypertrophy |
-1.6 | | Fitm1 | 'infarct and border region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
1.5 | | Fitm1 | 'high fat' vs 'chow' in 'NZO/HILtJ' | diet, strain | Transcription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ |
-1.5 | | Fitm1 | 'heterozygous RYR1 mutant' vs 'RYR1 wild type' in 'embryonic day 14.5' | developmental stage, genotype | Microarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels |
1.5 | | Fitm1 | 'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-1.5 | | Fitm1 | 'Rb^{lox/lox}; p130^{lox/lox}; p107+/-' vs 'wild type' | genotype | Transcription profiling by array of livers from the mouse model of human hepatocellular carcinoma |
1.5 | | Fitm1 | 'Sall4 homozygous knockout' vs 'wild type genotype' | genotype | RNA-Seq of Sall4 mutants in mouse embryonic stem cells |
-1.5 | | Fitm1 | 'unilateral ureteral obstruction' vs 'sham' in 'wild type' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
1.5 | | Fitm1 | '14 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
1.4 | | Fitm1 | 'high fat' vs 'chow' in 'WSB/EiJ' | diet, strain | Transcription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ |
-1.4 | | Fitm1 | 'Reverbαflox/floxAlbCreERT2+' vs 'wild type genotype' | genotype | Antibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq |
-1.4 | | Fitm1 | 'Soulatrolide; 20 milligram per kilogram per day' vs 'control; ' | compound | Toxicogenomics on mice liver of coumarins from Calophyllum brasiliense |
1.4 | | Fitm1 | 'Gabpa miRNA' vs 'control miRNA' in 'wild type genotype; re-fed' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
-1.4 | | Fitm1 | 'homozygous RYR1 mutant' vs 'RYR1 wild type' in 'embryonic day 14.5' | developmental stage, genotype | Microarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels |
-1.4 | | Fitm1 | 'L-Pex5 knock-out' vs 'wild type' | genotype | Transcription profiling by array of liver from L-Pex5 knock-out mice |
-1.4 | | Fitm1 | 'unilateral ureteral obstruction' vs 'sham' in 'TIMP2 -/-' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
-1.4 | | Fitm1 | 'diet restriction' vs 'control' | diet | Liver mRNA microarray study for mice treated with various diets |
1.4 | | Fitm1 | 'db/db' vs 'wild type genotype' in 'control miRNA; re-fed' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
1.4 | | Fitm1 | '11beta-HSD knockout' vs 'wild type' in 'subcutaneous adipose tissue' | genotype, organism part | Transcription profiling of adipose tissue from mesenteric and subcutaneous depots from 11beta-HSD1 knockout and wild type mice |
1.4 | | Fitm1 | '180 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
1.3 | | Fitm1 | 'high fat' vs 'chow' in 'C57BL/6J' | diet, strain | Transcription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ |
-1.3 | | Fitm1 | '3110043O21Rik knockout; liver' vs 'wild type genotype; liver' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
-1.3 | | Fitm1 | 'Lmna G609G/G609G knock in' vs 'wild type' | genotype | Transcription profiling by array of mouse liver with Lmna Gly609Gly knock in |
1.3 | | Fitm1 | 'Adrb1, Adrb2 and Adrb3 knockout' vs 'wild type genotype' in '20 to 22 degree celsius' | genotype, temperature | RNA-seq of cold-induced transcriptome changes in subcutaneous adipose tissue of beta-adrenergic receptor knockout mice |
1.3 | | Fitm1 | 'miR-1-133a_OSMR_tKO' vs 'miR-1-133a_dKO' | compound, genotype | Repression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart |
-1.2 | | Fitm1 | 'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-1.2 | | Fitm1 | 'CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype' | genotype, treatment | Gene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice. |
1.2 | | Fitm1 | 'Tris(2,3-dibromopropyl)phosphate; 1000 part per million; rodent chow' vs 'none; ; rodent chow' | compound, treatment | Transcription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals |
1.2 | | Fitm1 | 'high fat' vs 'control' | diet | Liver mRNA microarray study for mice treated with various diets |
-1.2 | | Fitm1 | 'heart-specific p53 and Mdm2 knockout; 7 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
1.2 | | Fitm1 | 'P19; transduced with MyoD lentivirus' vs 'P19; control' | cell line, treatment | Genetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling] |
1.1 | | Fitm1 | '1,4-Dichlorobenzene; 400 milligram per kilogram; corn oil' vs 'none; ; corn oil' | compound, treatment | Transcription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals |
1.1 | | Fitm1 | '1,4-Dichlorobenzene; 300 milligram per kilogram; corn oil' vs 'none; ; corn oil' | compound, treatment | Transcription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals |
-1.1 | | Fitm1 | 'TUT4 deficiency; TUT7 knockout' vs 'wild type' | phenotype | Microarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7 |
-1.1 | | Fitm1 | 'intermittent fasting every 16 hours' vs 'ad libitum' | diet | Genome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver |
1.1 | | Fitm1 | 'db/db' vs 'wild type genotype' in 'Gabpa miRNA; fasted' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
1.1 | | Fitm1 | 'high fat diet' vs 'regular chow diet' in 'wild type genotype' | diet, genotype | Transcription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet |
1.1 | | Fitm1 | '4-Nitroanthranilic acid; 10000 part per million; rodent chow' vs 'none; ; rodent chow' | compound, treatment | Transcription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals |
-1.1 | | Fitm1 | 'heart-specific Mdm2 knockout; 14 day' vs 'heart-specific Mdm2 knockout; 7 day' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
1.1 | | Fitm1 | '1-Amino-2,4-dibromoanthraquinone; 20000 part per million; rodent chow' vs 'none; ; rodent chow' | compound, treatment | Transcription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals |
1.1 | | Fitm1 | 'high fat diet' vs 'control' | diet | Transcription profiling by array of liver from mice fed a high fat diet |
-1.1 | | Fitm1 | 'KLF15 null' vs 'wild type genotype' in 'liver' | genotype, organism part | Transcription profiling of mouse livers and quadriceps muscles of Kruppel-like factor 15 (KLF15) null mutants after an overnight fast to provide insight into the role of KLF15 in gluconeogenesis |
-1.1 | | Fitm1 | 'YAP S127A' vs 'Empty vector' at '48 hour' | genotype, time | Transcription profiling by array of mouse primary myoblasts constitutively expressing Hippo pathway downstream effectors Yap or Taz against empty vector controls |
-1 | | Fitm1 | 'S-(1,2-dichlorovinyl)-L-cysteine; 15 milligram per kilogram; renal injury; 1 week' vs 'none; normal' | compound, disease, time | Expression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC |
1 | | Fitm1 | 'fenofibrate diet' vs 'control diet' | diet | Comparative transcriptomics and metabolomic analysis of fenofibrate and fish oil treatments in mice |
-1 | | Fitm1 | 'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-1 | | Fitm1 | 'Sik1 knockout; liver' vs 'wild type genotype; liver' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
-1 | | Fitm1 | 'CCl4; 1.6 gram per kilogram' at '48 hour' vs 'none' at '0 hour' | compound, time | Transcriptional responses in liver upon acute CCl4 intoxication |
-1 | | Fitm1 | 'Tbx5;Nkx2-5 knockout' vs 'wild type' | genotype | Transcription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse |
-1 | | Fitm1 | 'acute oropharyngeal candidiasis wild type mice'; female' vs 'healthy wild type genotype mice' | compound, disease, genotype, sex | Transcription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis |
-1 | | Fitm1 | 'antibiotics, CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype' | genotype, treatment | Gene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice. |
-1 | | Fitm1 | 'methionine- and choline-deficient, high fat diet' vs 'normal' | diet | Expression data from mouse liver treated with metformin |
-1 | | Fitm1 | 'Hepatic RXR_alpha-Knockout' vs 'wild type' in 'control' | genotype, treatment | Gene expression data of untreated and RA-treated wild type and RXRα-deficient mice liver |
-1 | | Fitm1 | 'miR-1-133a_dKO' vs 'wild type genotype' | compound, genotype | Repression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart |
-1 | | Fitm1 | 'atherogenic rodent' vs 'control' | diet | Liver mRNA microarray study for mice treated with various diets |
-1 | | Fitm1 | 'Reg3beta knockout' vs 'wild type' in 'tissue from infarction zone' | clinical information, genotype | myocardial infarction in Reg3beta knock-out mice |