ENSMUSG00000022951 (Rcan1)

mus musculus

regulator of calcineurin 1

Filter your results

Mus musculus
Organism part
Showing 56 experiments:
image/svg+xml aorta circulatory system blood vessel brown adipose tissue white adipose tissue skin stomach duodenum pancreas spleen adrenal gland kidney colon small intestine caecum jejunum ileum esophagus gall bladder parotid gland submandibular gland lymph node parathyroid gland tongue Peyer’s patch prostate gland vas deferens epididymis testis seminal vesicle penis urinary bladder thymus femur bone marrow cartilage quadriceps femoris spinal cord lung diaphragm peripheral nervous system trachea hindlimb trigeminal nerve eye sciatic nerve intestinal mucosa liver heart brain skeletal muscle
Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermhippocampuslungolfactory bulbskeletal muscle organtracheaaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartintestinal mucosalateral prominence neural epitheliummedial nasal prominencemuscle (biceps femoris)oviductpreoptic areaspleensubventricular zonevesicular glandwhole organism
T
49 FANTOM5 project - adult
T
49 FANTOM5 project - neonate
T
49 FANTOM5 project - juvenile
T
49 FANTOM5 project - embryonic day 18
T
49 FANTOM5 project - embryonic day 17
T
49 FANTOM5 project - embryonic day 16
T
49 FANTOM5 project - embryonic day 15
T
49 FANTOM5 project - embryonic day 14
T
49 FANTOM5 project - embryonic day 12
T
9 in 3 strains - DBA/2J
T
9 in 3 strains - CD1
T
9
T
14 - embryonic day 10.5
T
9 in 3 strains - C57BL/6
T
49 FANTOM5 project - embryonic day 13
T
Mammalian Kaessmann
T
GENCODE
T
6
T
Vertebrates
T
4
T
14 - embryonic day 9.5
T
14 - embryonic day 8.5
T
4 Bonthuis et al - CastEiJ
T
Developing gut
T
49 FANTOM5 project - embryonic day 11
T
3
T
Gregg et al - CAST/EiJ
T
Gregg et al - C57BL/6J
T
Gregg et al - (CAST/EiJ X C57BL/6J)F1
T
Gregg et al - (C57BL/6J X CAST/EiJ)F1
T
4 Bonthuis et al - (CastEiJ X …
T
4 Bonthuis et al - (C57BL/6J X …
T
Mernberger et al 2019 - Organism Part
T
49 FANTOM5 project - pregnant adult day …
T
49 FANTOM5 project - pregnant adult day …
T
3 Soumillon et al
T
2
T
Sun et al., 2020 - Organism part
T
4 Bonthuis et al - C57BL/6J
T
Fat and muscle
T
49 FANTOM5 project - pregnant adult day …
T
49 FANTOM5 project - pregnant adult day …
T
49 FANTOM5 project - pregnant adult day …
T
49 FANTOM5 project - lactating adult …
T
49 FANTOM5 project - embryonic day 17.5
T
49 FANTOM5 project - embryonic day 14.5
T
49 FANTOM5 project - embryo
T
4 Bonthuis et al - Idaho derived wild …
P
Huttlin et al., 2010 - tissues - brain, …
P
Linscheid et al., 2021 - tissue - heart …
P
Duda et al., 2018 - organism part - …
P
Duda et al., 2018 - organism part - …
P
Linscheid et al. 2019 - organism part
P
Deshmukh et al., 2015 - organism part
P
Zhao et al., 2019 - tissue - lens
P
Meierhofer et al., 2016 - organism part
P
Proteomics
T
Transcriptomics
High
Medium
Low
Below cutoff
No data available

Filter your results

Kingdom
Species
Experiment type
Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
4.7165 × 10-2285
Rcan1'lung carcinoma' vs 'normal' in 'CD11b+Ly6G+ neutrophil'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
2.7528 × 10-4-4
Rcan1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
5.398 × 10-73.6
Rcan1'CCl4; 1.6 gram per kilogram' at '2 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
8.3415 × 10-283.5
Rcan1'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
1.0404 × 10-863.2
Rcan1'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
7.7052 × 10-233.2
Rcan1'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
5.1247 × 10-5-3.2
Rcan1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.4234 × 10-343
Rcan1'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
2.2051 × 10-123
Rcan1'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
6.3123 × 10-73
Rcan1'cycloheximide and 100 unit per milliliter interferon alpha' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
1.5444 × 10-72.9
Rcan1'confluent monolayer on collagen' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.337 × 10-82.8
Rcan1'CCl4; 1.6 gram per kilogram' at '8 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
5.0789 × 10-62.8
Rcan1'cycloheximide' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
2.1956 × 10-4-2.7
Rcan1'70 week' vs '6 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
4.1031 × 10-572.5
Rcan1'Adjuvant System 03' at '4 hour' vs 'none'compound, timeRNA-Seq of RAW 264.7 cells stimulated with the AS03 adjuvant after 4 and 8 hours
Adjusted p-valueLog2-fold change
6.6688 × 10-302.5
Rcan1'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
7.4375 × 10-122.5
Rcan1'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.8836 × 10-72.5
Rcan1'collagen sandwich' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
6.508 × 10-3-2.5
Rcan1'6 month; RXRa hepatic deficiency; male' vs '6 month; wild type; male'age, genotype, sexTranscription profiling of liver from wild type and RXR-alpha deficient matured and aged mcie
Adjusted p-valueLog2-fold change
8.3621 × 10-452.4
Rcan1'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
9.1317 × 10-212.4
Rcan1'lung carcinoma' vs 'normal' in 'lung cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
8.4204 × 10-152.4
Rcan1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.1806 × 10-4-2.4
Rcan1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
4.9259 × 10-142.3
Rcan1'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.7391 × 10-62.3
Rcan1'cycloheximide and 100 unit per milliliter interferon gamma' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
7.8344 × 10-622.2
Rcan1'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; MEF2C/D knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.157 × 10-92.2
Rcan1'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
4.5967 × 10-82.2
Rcan1'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.6473 × 10-42.2
Rcan1'infarct and border region of left ventricle 1 day post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
8.727 × 10-42.1
Rcan1'acute oropharyngeal candidiasis wild type mice'; female' vs 'healthy wild type genotype mice'compound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
5.534 × 10-142
Rcan1'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
9.981 × 10-72
Rcan1'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.5749 × 10-52
Rcan1'tristetrapolin knockout' vs 'wild type' in 'none' at '0 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
3.0977 × 10-52
Rcan1'alphaMHC-Cre+/0;MAT1F/F' vs 'alphaMHC-Cre+/0;MAT1F/+' in '4 week'age, genotypeTranscription profiling of mouse heart from cardiac-specific conditional knockout deletion of menage-a-trios-1 (MAT1)
Adjusted p-valueLog2-fold change
3.8483 × 10-52
Rcan1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '30 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
5.4732 × 10-32
Rcan1'Staphylococcus aureus cutaneous infection' vs 'none' in 'IL-1R knockout'disease, genotypeNeutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice
Adjusted p-valueLog2-fold change
2.2863 × 10-22
Rcan1'cecal ligation and puncture surgery' vs 'sham surgery' in 'PPTA knockout'clinical treatment, genotypeGene expression profile in lung tissue 8 h after inducing polymicrobial sepsis in preprotachykinin-A (PPTA) knockout mice and wild type
Adjusted p-valueLog2-fold change
5.6534 × 10-571.9
Rcan1'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.7091 × 10-81.9
Rcan1'cardiotoxin; 10 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq comparison of fibro-adipogenic progenitors (FAPs) from wild type, mdx and cardiotoxin-injured mice
Adjusted p-valueLog2-fold change
4.688 × 10-21.9
Rcan1'Sox17.Epi' vs 'Sox17.Endo'genotypeTranscription profiling by high throughput sequencing of Sox17.Epi and Endo cells from mouse embryos
Adjusted p-valueLog2-fold change
6.6421 × 10-351.8
Rcan1'Adjuvant System 03' at '8 hour' vs 'none'compound, timeRNA-Seq of RAW 264.7 cells stimulated with the AS03 adjuvant after 4 and 8 hours
Adjusted p-valueLog2-fold change
3.3246 × 10-25-1.8
Rcan1'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
3.2293 × 10-171.8
Rcan1'reduced expression of miR-25' vs 'wild type'phenotypeTranscription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice
Adjusted p-valueLog2-fold change
7.4813 × 10-71.8
Rcan1'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.1478 × 10-61.8
Rcan1'transverse aortic constriction' vs 'sham transverse aortic constriction'treatmentTranscriptional profiling of mouse heat left ventricle after dfferential cardiac remodeling in preload versus afterload.
Adjusted p-valueLog2-fold change
9.7176 × 10-4-1.8
Rcan1'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
1.5713 × 10-21.8
Rcan1'aortic banding' at '24 hour' vs 'sham' at '24 hour'injury, timeTranscription profiling of heart ventricles from mice at different time points after surgical intervention for pressure-overload induced hypertrophy to identify differentially expressed genes.
Adjusted p-valueLog2-fold change
3.0555 × 10-361.7
Rcan1'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
9.7386 × 10-281.7
Rcan1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.6434 × 10-211.7
Rcan1'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.1841 × 10-61.7
Rcan1'confluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.8344 × 10-61.7
Rcan1'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
1.4544 × 10-5-1.7
Rcan1'heart-specific p53 and Mdm2 knockout; 1 day' vs 'wild type phenotype'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
2.5803 × 10-5-1.7
Rcan1'intermittent fasting every 16 hours' vs 'ad libitum'dietGenome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver
Adjusted p-valueLog2-fold change
5.1989 × 10-51.7
Rcan1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '120 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
9.8777 × 10-51.7
Rcan1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '90 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
1.0677 × 10-31.7
Rcan1'infarct and border region of left ventricle 1 day post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; MRL/MpJ'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
9.0018 × 10-111.6
Rcan1'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
9.1399 × 10-71.6
Rcan1'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
9.1793 × 10-51.6
Rcan1'overexpression of CA-NFATc3' vs 'control'phenotypeExpression data from embryonic stem cells differentiation
Adjusted p-valueLog2-fold change
8.2618 × 10-31.6
Rcan1'paracetamol; 529 milligram per kilogram' vs 'vehicle' at '4 hour'compound, timeTranscription profiling by array of CD1 mice after nontoxic and nonlethal hepatotoxic paracetamol administration
Adjusted p-valueLog2-fold change
1.4657 × 10-21.6
Rcan1'Taf10-/-' vs 'wild type'genotypeTranscription profiling by array of liver from Taf10 knock out mice
Adjusted p-valueLog2-fold change
3.3985 × 10-21.6
Rcan1'Tyr mutant' vs 'wild type'genotypeMicroarray analysis of iris gene expression in mice with mutations relevant to glaucoma
Adjusted p-valueLog2-fold change
3.6417 × 10-21.6
Rcan1'aortic banding' at '4 hour' vs 'sham' at '4 hour'injury, timeTranscription profiling of heart ventricles from mice at different time points after surgical intervention for pressure-overload induced hypertrophy to identify differentially expressed genes.
Adjusted p-valueLog2-fold change
1.0505 × 10-201.5
Rcan1'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.0895 × 10-171.5
Rcan1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.0145 × 10-61.5
Rcan1'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.4667 × 10-61.5
Rcan1'NOD' vs 'C57BL/6' in 'PBS stimulation' at '18 hour'strain, time, treatmentExpression data from NOD and C57BL/6 mouse pancreas CD8α- Dendritic Cells (DCs) under steady-state and after in-vitro LPS stimulation
Adjusted p-valueLog2-fold change
3.7979 × 10-41.5
Rcan1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '60 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
4.6912 × 10-4-1.5
Rcan1'heart-specific Mdm2 knockout; 7 day' vs 'wild type phenotype'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
5.6552 × 10-41.5
Rcan1'conditional UPF2 knockout; before partial hepatechtomy' vs 'control; before partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
8.8308 × 10-41.5
Rcan1'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha'genotype, stimulusRNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment
Adjusted p-valueLog2-fold change
1.1338 × 10-21.5
Rcan1'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.4137 × 10-21.5
Rcan1'heart; 1 day' vs 'heart; 0 day'organism part, timeExpression data from mouse tissue Angiotensin II treated for 0,1,3,7days
Adjusted p-valueLog2-fold change
1.5058 × 10-21.5
Rcan1'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.64 × 10-21.5
Rcan1'50 micromolar; hydrogen peroxide' vs 'none'compoundTranscription profiling by array of mouse dermal fibroblasts after treatment with hydrogen peroxide
Adjusted p-valueLog2-fold change
2.86 × 10-2-1.5
Rcan1'PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.9419 × 10-21.5
Rcan1'cecal ligation and puncture surgery; PPTA knockout' vs 'cecal ligation and puncture surgery; wild type'clinical treatment, genotypeGene expression profile in lung tissue 8 h after inducing polymicrobial sepsis in preprotachykinin-A (PPTA) knockout mice and wild type
Adjusted p-valueLog2-fold change
3.2318 × 10-2-1.5
Rcan1'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
3.5888 × 10-2-1.5
Rcan1'ko cyld-/-' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Cyld inactivation
Adjusted p-valueLog2-fold change
7.1174 × 10-1241.4
Rcan1'Debaryomyces hansenii' at '2 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
5.1774 × 10-201.4
Rcan1'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; MEF2C/D knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.1947 × 10-17-1.4
Rcan1'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.8295 × 10-11-1.4
Rcan1'prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; MEF2C/D knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.2501 × 10-111.4
Rcan1'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.5821 × 10-81.4
Rcan1'seizure-preconditioning followed by intra-amygdala kainic acid' vs 'sham-preconditioning followed by intra-amygdala vehicle'clinical treatmentTranscription profiling by array of mice with epileptic tolerance
Adjusted p-valueLog2-fold change
2.8506 × 10-61.4
Rcan1'confluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
6.1884 × 10-61.4
Rcan1'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
8.433 × 10-61.4
Rcan1'Adjuvant System 03' vs 'PBS' in 'lymph node' at '4 hour'organism part, stimulus, timeExpression data from draining lymph node and muscle of mice immunised with AS03 or PBS
Adjusted p-valueLog2-fold change
3.0832 × 10-41.4
Rcan1'SARS coronavirus MA15 dORF6' vs 'none' at '2 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
7.4833 × 10-4-1.4
Rcan1'fasted' vs 're-fed' in 'db/db; Gabpa miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
1.4366 × 10-31.4
Rcan1'aortic banding' at '48 hour' vs 'sham' at '48 hour'injury, timeTranscription profiling of heart ventricles from mice at different time points after surgical intervention for pressure-overload induced hypertrophy to identify differentially expressed genes.
Adjusted p-valueLog2-fold change
1.4839 × 10-3-1.4
Rcan1'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'Nfkbiz-/-'compound, genotypeInhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2)
Adjusted p-valueLog2-fold change
1.8704 × 10-31.4
Rcan1'Escherichia coli O18:K1:H7; 2 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
4.6031 × 10-31.4
Rcan1'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
8.3695 × 10-31.4
Rcan1'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in '129S1/SvImJ'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.7628 × 10-21.4
Rcan1'Staphylococcus aureus cutaneous infection' vs 'none' in 'wild type'disease, genotypeNeutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice
Adjusted p-valueLog2-fold change
1.8316 × 10-21.4
Rcan1'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
3.5218 × 10-2-1.4
Rcan1'acute oropharyngeal candidiasis in IL-17A knockout mice' vs 'acute oropharyngeal candidiasis in wild type genotype mice'compound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
4.5607 × 10-21.4
Rcan1'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar and interferon beta; 100 units per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
4.9068 × 10-2-1.4
Rcan1'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs'growth conditionRNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs
Adjusted p-valueLog2-fold change
9.7466 × 10-181.3
Rcan1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.4826 × 10-17-1.3
Rcan1'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
7.7714 × 10-10-1.3
Rcan1'Stella maternal / zygotic knockout' vs 'wild type genotype' in '1-cell embryo'developmental stage, genotypeTranscription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development
Adjusted p-valueLog2-fold change
2.049 × 10-81.3
Rcan1'sham-preconditioning followed by intra-amygdala kainic acid' vs 'sham-preconditioning followed by intra-amygdala vehicle'clinical treatmentTranscription profiling by array of mice with epileptic tolerance
Adjusted p-valueLog2-fold change
2.4659 × 10-81.3
Rcan1'phenylephrine; 30 milligram per kilogram per day' vs 'vehicle'compoundRNA-seq of myocytes from mice treated in vivo for 3 days with vehicle, angiotensin II, or phenylephrine
Adjusted p-valueLog2-fold change
5.2189 × 10-81.3
Rcan1'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
1.7763 × 10-51.3
Rcan1'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
6.7959 × 10-51.3
Rcan1'Dmd-mdx mutation' vs 'wild type genotype' in 'none'compound, genotypeRNA-seq comparison of fibro-adipogenic progenitors (FAPs) from wild type, mdx and cardiotoxin-injured mice
Adjusted p-valueLog2-fold change
9.0793 × 10-51.3
Rcan1'heart-specific p53 and Mdm2 knockout; 7 day' vs 'heart-specific p53 and Mdm2 knockout; 1 day'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
2.3187 × 10-41.3
Rcan1'control; streptozotocin-induced diabetes' vs 'control; control'diet, phenotypeHepatic gene expression in streptozotocin-induced diabetic mice fed a phloridzin diet
Adjusted p-valueLog2-fold change
6.0671 × 10-41.3
Rcan1'Gata4+/-' vs 'wild type genotype' in 'TAC-mediated heart pressure overload'environmental stress, genotypeTranscription profiling of hearts from mice heterozygous for Gata4 mutation (G4D) to investigate the significance of Gata4 in regulating postnatal heart function and in regulating the hypertrophic response of the heart to pathological stress.
Adjusted p-valueLog2-fold change
6.472 × 10-41.3
Rcan1'SARS coronavirus MA15' vs 'none' at '1 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
6.662 × 10-41.3
Rcan1'high fat diet' vs 'regular chow diet' in 'wild type genotype'diet, genotypeTranscription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
Adjusted p-valueLog2-fold change
4.0267 × 10-31.3
Rcan1'chemical hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo.
Adjusted p-valueLog2-fold change
1.311 × 10-2-1.3
Rcan1'AhCre Apc Floxed Cited1 knockout' vs 'control'genotypeCited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis
Adjusted p-valueLog2-fold change
4.6254 × 10-21.3
Rcan1'Tyrp1, Gpnmb double mutant' vs 'wild type'genotypeMicroarray analysis of iris gene expression in mice with mutations relevant to glaucoma
Adjusted p-valueLog2-fold change
8.4659 × 10-301.2
Rcan1"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "PWK/PhJ"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
2.9338 × 10-131.2
Rcan1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
7.8392 × 10-101.2
Rcan1"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "C57BL/6J x WSB/EiJ F1 cross"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
8.6604 × 10-9-1.2
Rcan1'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'neutrophil'cell type, genotypeRNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice
Adjusted p-valueLog2-fold change
3.638 × 10-61.2
Rcan1'cardiac-specific constitutive expression of an activated Akt (caAkt)' vs 'wild type genotype'genotypeTranscription profiling by array of cardic ventricle tissues from mice with cardiac-specific constitutive expression of an activated Akt (caAkt) and wild-type controls to test whether Akt activation contributes to mitochondrial dysfunction in pathological cardiac hypertrophy
Adjusted p-valueLog2-fold change
2.3822 × 10-51.2
Rcan1'non-infarct region of left ventricle 5 days post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as non-infarct tissue in post-myocardial infarction hearts; MRL/MpJ'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
7.7635 × 10-5-1.2
Rcan1'heart-specific p53 knockout; 28 day' vs 'wild type phenotype'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
9.4648 × 10-5-1.2
Rcan1'heart-specific p53 knockout; 7 day' vs 'wild type phenotype'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
1.0797 × 10-41.2
Rcan1'Adjuvant System 03' vs 'PBS' in 'lymph node' at '6 hour'organism part, stimulus, timeExpression data from draining lymph node and muscle of mice immunised with AS03 or PBS
Adjusted p-valueLog2-fold change
1.5001 × 10-41.2
Rcan1'macrophage; lipopolysaccharide stimulated' vs 'macrophage; unstimulated'cell type, treatmentGene expression profile of GM-CSF derived bone marrow dendritic cell subsets after LPS stimulation
Adjusted p-valueLog2-fold change
2.4487 × 10-41.2
Rcan1'transverse aortic constriction' vs 'sham surgery' at '10 day'clinical treatment, timeTranscription profiling of mouse gene expression after transverse aortic constriction in mice: comparison of TAC vs. sham group at 2, 10 and 21 days to identify the differential expression of genes
Adjusted p-valueLog2-fold change
7.3956 × 10-41.2
Rcan1'Adjuvant System 03' vs 'PBS' in 'lymph node' at '2 hour'organism part, stimulus, timeExpression data from draining lymph node and muscle of mice immunised with AS03 or PBS
Adjusted p-valueLog2-fold change
4.1464 × 10-31.2
Rcan1'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
4.7461 × 10-31.2
Rcan1'infarct and border region of left ventricle 5 days post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; MRL/MpJ'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
8.2533 × 10-31.2
Rcan1'control; 36 hour after partial hepatechtomy' vs 'control; before partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
2.3414 × 10-21.2
Rcan1'non-infarct region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as non-infarct tissue in post-myocardial infarction hearts; C57BL/6J'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
3.3644 × 10-21.2
Rcan1'aortic banding' at '168 hour' vs 'sham' at '168 hour'injury, timeTranscription profiling of heart ventricles from mice at different time points after surgical intervention for pressure-overload induced hypertrophy to identify differentially expressed genes.
Adjusted p-valueLog2-fold change
2.5618 × 10-271.1
Rcan1'interleukin-13 (Mus musculus); 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
7.6218 × 10-20-1.1
Rcan1'Duchenne muscular dystrophy' vs 'normal'diseaseRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Adjusted p-valueLog2-fold change
1.9082 × 10-111.1
Rcan1'SARS coronavirus MA15; 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.1344 × 10-8-1.1
Rcan1'Stella knockout' vs 'wild type genotype' in 'oocyte'developmental stage, genotypeTranscription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development
Adjusted p-valueLog2-fold change
4.8951 × 10-71.1
Rcan1'induced neural stem cell' vs 'neural stem cell'cell typeGene expression profile of mouse induced neural stem cells
Adjusted p-valueLog2-fold change
2.6943 × 10-61.1
Rcan1'5-aza-2'-deoxycytidine; 5 micromolar' vs 'none'compoundTranscription profiling by array of mouse primary dermal fibroblasts after treatment with 5-aza-2'-deoxycytidine
Adjusted p-valueLog2-fold change
1.4705 × 10-51.1
Rcan1'SR-BI-/- apoE-/-' vs 'control' in '43 day; Chow diet'age, diet, genotypeExpression data from the hearts of a mouse model of spontaneous myocardial infarction
Adjusted p-valueLog2-fold change
8.4878 × 10-51.1
Rcan1'infarct and border region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
8.6416 × 10-51.1
Rcan1'7-ketocholesterol' vs 'vehicle (cyclodextrin)'compound, timeArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
Adjusted p-valueLog2-fold change
1.0797 × 10-41.1
Rcan1'Metarhizium anisopliae crude antigen' vs 'vehicle' at '3 hour'compound, timeTranscription profiling of mouse lungs following exposure to agents of high or low allergenicity
Adjusted p-valueLog2-fold change
1.2874 × 10-4-1.1
Rcan1'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.6843 × 10-41.1
Rcan1'dominant-negative Brg1' vs 'wild type'genotypeTranscription profiling by array of lens tissue from mice expressing a dnBrg1 transgenic construct
Adjusted p-valueLog2-fold change
2.1497 × 10-41.1
Rcan1'SARS coronavirus MA15' vs 'none' in 'STAT1 -/-' at '5 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds
Adjusted p-valueLog2-fold change
2.6018 × 10-4-1.1
Rcan1'fasted' vs 're-fed' in 'wild type genotype; Gabpa miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
2.0601 × 10-3-1.1
Rcan1'intermittent fasting every 24 hours' vs 'ad libitum'dietGenome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver
Adjusted p-valueLog2-fold change
2.7318 × 10-31.1
Rcan1'8 month; diabetes mellitus' vs '8 month; normal'age, diseaseGene expression in OVE26 diabetic kidney during the development of nephropathy
Adjusted p-valueLog2-fold change
5.6195 × 10-31.1
Rcan1'CCl4; 1.6 gram per kilogram' at '24 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
6.4281 × 10-31.1
Rcan1'db/db' vs 'wild type genotype' in 'control miRNA; re-fed'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
9.1025 × 10-31.1
Rcan1'lipid nanoparticle complexed with ribonucleic acid expressing respiratory synctial virus F protein' vs 'phosphate buffered saline'stimulusMicroarray analysis of mouse whole genome using self-amplifying messenger (SAM) RNA delivered with different formulations compared to controls
Adjusted p-valueLog2-fold change
9.7224 × 10-31.1
Rcan1'side population cells' vs 'main population cells' in 'muscle'cell type, organism partGene expression of side population and main population cells, isolated from adult murine skeletal muscle and bone marrow
Adjusted p-valueLog2-fold change
1.5505 × 10-2-1.1
Rcan1'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.7233 × 10-2-1.1
Rcan1'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.7909 × 10-21.1
Rcan1'TAC surgery' vs 'sham surgery' in 'C57BL/6J'strain, treatmentTranscription profiling of left ventricular myocardium after sham or TAC surgery in BL/6N and BL/6J mice
Adjusted p-valueLog2-fold change
1.8343 × 10-2-1.1
Rcan1'fasted' vs 're-fed' in 'db/db; control miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
1.8818 × 10-2-1.1
Rcan1'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
2.1694 × 10-21.1
Rcan1'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'BALB/cByJ'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
2.5999 × 10-21.1
Rcan1'wounded skin; PKC alpha-/-' vs 'wounded skin; wild type genotype'clinical history, genotypeAltered dermal architecture in PKCα-/- skin
Adjusted p-valueLog2-fold change
1.6454 × 10-39-1
Rcan1'Debaryomyces hansenii' at '24 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
1.2034 × 10-231
Rcan1"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "C57BL/6J x 129S1Sv/ImJ F1 cross"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
2.8081 × 10-171
Rcan1"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "C57BL/6J x NZO/H1LtJ F1 cross"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
7.5668 × 10-91
Rcan1'10 month' vs '2 month'ageRNA-seq of adipocyte progenitor cells derived from old and young mice to investigate the molecular signature of aging
Adjusted p-valueLog2-fold change
2.7343 × 10-71
Rcan1'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
5.0623 × 10-71
Rcan1'Zbtb10 knockdown' vs 'control' at '2 hour'genotype, timeRNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+)
Adjusted p-valueLog2-fold change
9.1723 × 10-71
Rcan1'SARS coronavirus MA15; 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.5511 × 10-6-1
Rcan1'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
3.6951 × 10-51
Rcan1'p19Arf and interferon beta' vs 'eGFP control'genotypeTranscription profiling by microarray of mouse B16F10 cells transduced with cDNAs encoding eGFP control, p19Arf, murine interferon-beta (IF-B) or the combination of p19Arf plus IF-B to study the modulated genes
Adjusted p-valueLog2-fold change
4.9751 × 10-51
Rcan1'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.0527 × 10-41
Rcan1'4 day' vs '1 day' in 'influenza A infected DBA/2J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
4.1005 × 10-41
Rcan1'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.2462 × 10-31
Rcan1'non-infarct region of left ventricle 1 day post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as non-infarct tissue in post-myocardial infarction hearts; C57BL/6J'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
1.4943 × 10-31
Rcan1'heart-specific Mdm2 knockout; 14 day' vs 'heart-specific Mdm2 knockout; 7 day'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
1.6623 × 10-3-1
Rcan1'Nr1d1-/-' vs 'wild type genotype'genotypeTranscription profiling by array of liver tissues from wild type and Rev-erb{alpha} knockout (Nr1d1-/-) mice to study direct targets of Nr1d1 in rhythmic (circadian) transcription
Adjusted p-valueLog2-fold change
2.236 × 10-31
Rcan1'transgenic' vs 'wild type' in '121 day; 129Sv'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
2.6036 × 10-31
Rcan1'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
2.9322 × 10-31
Rcan1'4 month; diabetes mellitus' vs '4 month; normal'age, diseaseGene expression in OVE26 diabetic kidney during the development of nephropathy
Adjusted p-valueLog2-fold change
4.5814 × 10-31
Rcan1'CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
5.6485 × 10-31
Rcan1'control mice [Gp130f/f]; cecal ligation and puncture' vs 'control mice [Gp130f/f]; control'genotype, treatmentHepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function
Adjusted p-valueLog2-fold change
7.4443 × 10-31
Rcan1'SARS coronavirus MA15 E protein mutant Δ5' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
7.6448 × 10-31
Rcan1'transverse aortic constriction' vs 'sham surgery' at '2 day'clinical treatment, timeTranscription profiling of mouse gene expression after transverse aortic constriction in mice: comparison of TAC vs. sham group at 2, 10 and 21 days to identify the differential expression of genes
Adjusted p-valueLog2-fold change
7.9244 × 10-3-1
Rcan1'Stella maternal / zygotic knockout' vs 'wild type genotype' in '2-cell embryo'developmental stage, genotypeTranscription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development
Adjusted p-valueLog2-fold change
1.0503 × 10-21
Rcan1'transverse aortic constriction' vs 'sham surgery' at '21 day'clinical treatment, timeTranscription profiling of mouse gene expression after transverse aortic constriction in mice: comparison of TAC vs. sham group at 2, 10 and 21 days to identify the differential expression of genes
Adjusted p-valueLog2-fold change
2.3053 × 10-21
Rcan1'H-Ras expression; c-Myc activation' vs 'wild type'phenotypeRNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls.
Adjusted p-valueLog2-fold change
2.4562 × 10-21
Rcan1'SARS coronavirus MA15 dORF6' vs 'SARS coronavirus MA15' at '2 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
4.4636 × 10-2-1
Rcan1'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout'compound, genotypeLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Synonym
Dscr1, MCIP1, 2410048A02Rik, ADAPT78, CSP1
Ortholog
rcan-1 (Caenorhabditis elegans), RCAN1 (Gallus gallus), rcan1 (Xenopus tropicalis), ENSCING00000013221 (Ciona intestinalis), RCAN1 (Bos taurus), sra (Drosophila melanogaster), RCAN1 (Equus caballus), ENSCSAG00000008724 (Chlorocebus sabaeus), ENSACAG00000005089 (Anolis carolinensis), ENSOARG00020005458 (Ciona intestinalis), ENSGGOG00000040245 (Gorilla gorilla), ENSMODG00000021053 (Monodelphis domestica), ENSDARG00000099004 (Danio rerio), ENSAPLG00000007074 (Anas platyrhynchos), RCAN1 (Pan troglodytes), RCAN1 (Homo sapiens), rcan1a (Tetraodon nigroviridis), RCAN1 (Macaca mulatta), rcan1a (Danio rerio), Rcan1 (Rattus norvegicus), ENSOANG00000048939 (Ornithorhynchus anatinus), ENSDNOG00000012603 (Dasypus novemcinctus), RCAN1 (Pongo abelii), RCAN1 (Sus scrofa), ENSOCUG00000010604 (Oryctolagus cuniculus), RCAN1 (Papio anubis)
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
4450704, 1416601_a_at, 4366943, ILMN_2701991, 4532400, 4587124, W30069_s_at, 4564268, 4567413, 4760659, 4604008, 5020183, 5004213, 5267168, 5563144, ILMN_2469555, 5544334, A_51_P182116, 4323193, 5104791, 5354804, w91146_s_at, 1416600_a_at, 5507220, 4485848, 17332228, 5453624, 10440993, A_52_P617327, 100555_at, ILMN_1259180