ENSMUSG00000024471 (Myot)

mus musculus

myotilin

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Mus musculus
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Showing 2 experiments:
Created with Highcharts 6.2.0adult CCAP neuronalpha’/beta’ middle Kenyon cellcentrifugal neuron C3distal medullary amacrine neuron Dm10distal medullary amacrine neuron Dm9dopaminergic PAM neuron 6gamma dorsal Kenyon celllamina monopolar neuron L2lobula columnar neuron LC10alobula columnar neuron LC6lobula-lobula plate columnar neuron LLPC1mushroom body output neuronproximal medullary amacrine neuron Pm3transmedullary neuron Tm1transmedullary neuron Tm4adult lamina marginal glial cellalpha/beta posterior Kenyon cellcolumnar neuron T1distal medullary amacrine neuron Dm3dopaminergic PAM neuron 3dopaminergic PAM neuron 9lamina intrinsic neuronlamina monopolar neuron L5lobula columnar neuron LC10dlobula plate tangential neuronmedullary intrinsic neuron Mi4photoreceptor cell R7T neurontransmedullary neuron Tm29
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.9911 × 10-89.6
Myot'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
3.2306 × 10-219
Myot'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
7.802 × 10-7-7.2
Myot'70 week' vs '6 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
2.3951 × 10-6-6.8
Myot'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
2.9411 × 10-76.1
Myot'144 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
7.5098 × 10-4-5.9
Myot'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal'diseaseTranscription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma
Adjusted p-valueLog2-fold change
1.2858 × 10-8-5.8
Myot'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
7.4022 × 10-115.4
Myot'embryonic day 16.5' vs 'embryonic day 11.5'developmental stageGene expression profile of diaphragm morphogenesis at different developmental stages
Adjusted p-valueLog2-fold change
9.3132 × 10-3-5.4
Myot'synovial sarcoma' vs 'normal'diseaseTranscription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice
Adjusted p-valueLog2-fold change
8.3126 × 10-115.2
Myot'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.2864 × 10-4-5.2
Myot'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
1.775 × 10-95.1
Myot'6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
2.9105 × 10-55
Myot'96 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
3.5926 × 10-104.9
Myot'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
8.0152 × 10-8-4.9
Myot'cardiac-specific constitutive expression of an activated Akt (caAkt)' vs 'wild type genotype'genotypeTranscription profiling by array of cardic ventricle tissues from mice with cardiac-specific constitutive expression of an activated Akt (caAkt) and wild-type controls to test whether Akt activation contributes to mitochondrial dysfunction in pathological cardiac hypertrophy
Adjusted p-valueLog2-fold change
5.7846 × 10-11-4.8
Myot'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
8.8341 × 10-34.8
Myot'ulcer' vs 'distant normal tissue' in 'Bmp4 overexpression'genotype, sampling site, timeIntestinal ulcers from biopsy-wounded wild-type and Bmp4-overexpressing mice
Adjusted p-valueLog2-fold change
4.8996 × 10-2-4.8
Myot'30 month' vs '5 month' in 'male'age, block, sexExpression data from tail skin in young (5 months) and old (30 months) CB6F1 mice
Adjusted p-valueLog2-fold change
6.1865 × 10-124.6
Myot'liver-specific Cnot1 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
1.2004 × 10-54.6
Myot'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
3.42 × 10-4-4.2
Myot'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.4184 × 10-83.9
Myot'6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
1.8163 × 10-43.9
Myot'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
3.1031 × 10-43.9
Myot'L-Pex5 knock-out' vs 'wild type'genotypeTranscription profiling by array of liver from L-Pex5 knock-out mice
Adjusted p-valueLog2-fold change
6.1679 × 10-123.8
Myot'colitis' at '12 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
2.0181 × 10-5-3.8
Myot'carcinoma' vs 'normal'diseaseGene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse
Adjusted p-valueLog2-fold change
3.4318 × 10-53.7
Myot'Trichuris muris' vs 'control' in 'non wormy; caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
1.4544 × 10-3-3.7
Myot'8 week; Str/ort' vs '8 week; CBA'age, strainExpression data of cartiliage from CBA and STR/ORT mice
Adjusted p-valueLog2-fold change
2.6241 × 10-6-3.6
Myot'no limb muscle' vs 'wild type'phenotypeTranscription profiling by array of TS23 humerus tissue from muscle-less mutant (splotch-delayed) mice and control littermates to identify differentially expressed genes between muscle-less and control embryonic (TS23) humerus tissue, in order to determine mechanosensitive genes that impact skeletal development
Adjusted p-valueLog2-fold change
1.1802 × 10-43.5
Myot'Citrobacter rodentium' vs 'none'infectRNAseq of colon intestinal epithelium extracted from mice infected with Citrobacter rodentium
Adjusted p-valueLog2-fold change
1.8691 × 10-6-3.3
Myot'Mycobacterium tuberculosis; C57BL/6J; 30 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
1.7392 × 10-6-3.2
Myot'Mycobacterium tuberculosis; C57BL/6J; 70 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
1.0689 × 10-43.2
Myot'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
3.3698 × 10-33.2
Myot'diabetes mellitus' vs 'normal' in 'ApoE RAGE double knockout'disease, genotypeGene Expression of ApoE Null and ApoE Null/RAGE Diabetic and Non-diabetic Mice
Adjusted p-valueLog2-fold change
1.5883 × 10-2-3.2
Myot'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
3.3293 × 10-2-3.2
Myot'expression of a dominant negative form of MCU' vs 'wild type' in 'adult'developmental stage, phenotypemRNA Expression Changes Induced by Myocardial MCU Inhibition
Adjusted p-valueLog2-fold change
2.8739 × 10-53.1
Myot'Dicer knock out' vs 'wild type'genotypeTranscription profiling by array of mouse Dicer-deficient ooctyes
Adjusted p-valueLog2-fold change
1.071 × 10-43.1
Myot'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
2.5197 × 10-3-3.1
Myot'uterine-specific Tsc2-null' vs 'wild type' in '17beta-estradiol'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
1.6482 × 10-2-3.1
Myot'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 30 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
1.0207 × 10-83
Myot'Aire knockout' vs 'wild type' in 'cTEC'genotype, phenotypeTranscription profiling by high throughput sequencing of primary cTEC, mTEClo, and mTEChi harvested from wild type and Aire-deficient mice
Adjusted p-valueLog2-fold change
1.1077 × 10-7-3
Myot'bronchoalveolar adenocarcinoma induced using doxycycline' vs 'normal'diseaseTranscription profiling by array of lung alveolar type II epithelial cells with bronchoalveolar adenocarcinoma
Adjusted p-valueLog2-fold change
3.2485 × 10-73
Myot'mPIN (mouse prostatic intraepithelial neoplasia)' vs 'normal'diseaseTranscription profiling by array of ventral prostates of wild type and p110 beta transgenic mice to investigate prostate cancer
Adjusted p-valueLog2-fold change
2.1527 × 10-23
Myot'Taf10-/-' vs 'wild type'genotypeTranscription profiling by array of liver from Taf10 knock out mice
Adjusted p-valueLog2-fold change
5.8086 × 10-4-2.9
Myot'30 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
1.3268 × 10-3-2.9
Myot'70 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
7.1728 × 10-3-2.9
Myot'UO126; 0.2 milligram per kilogram; miR-1-133a_dKO' vs 'wild type genotype'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
1.7264 × 10-4-2.8
Myot'doxorubicin; 15 milligram per kilogram; CHIP knockout' vs 'doxorubicin; 15 milligram per kilogram; wild type'compound, genotypeExpression data from DOX(doxorubicin) -treated wild type or CHIP knockout C57BL/6J mice at day 5
Adjusted p-valueLog2-fold change
1.0085 × 10-2-2.8
Myot'PolgD257A/D257A' vs 'wild type'genotypeTranscription profiling by array of cochlea from PolgD257A/D257A mice
Adjusted p-valueLog2-fold change
9.3845 × 10-102.7
Myot'3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
8.6243 × 10-72.7
Myot'dextran sodium sulfate' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq analysis of colonic intestinal epithelial cells (IECs) isolated from naive wild-type C57BL/6 mice, DSS-treated wild-type C57BL/6 mice, Il10-/- C57BL/6 mice and Il10-/- C57BL/6 mice with IEC-specific Rabgef1 deletion
Adjusted p-valueLog2-fold change
2.638 × 10-5-2.7
Myot'none; ; CHIP knockout' vs 'none; ; wild type'compound, genotypeExpression data from DOX(doxorubicin) -treated wild type or CHIP knockout C57BL/6J mice at day 5
Adjusted p-valueLog2-fold change
3.519 × 10-6-2.6
Myot'heart-specific p53 and Mdm2 knockout; 7 day' vs 'heart-specific p53 and Mdm2 knockout; 1 day'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
2.7169 × 10-5-2.6
Myot'inh-alpha/Tag transgenic' vs 'wild type' in 'none'compound, genotypeNovel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice.
Adjusted p-valueLog2-fold change
2.9166 × 10-5-2.6
Myot'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
4.1541 × 10-72.5
Myot'AR3 transgenic' vs 'wild type'genotypeExpression data from AR3 transgenic and wild-type mouse prostates
Adjusted p-valueLog2-fold change
7.5603 × 10-82.4
Myot'6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
2.1978 × 10-5-2.4
Myot'heterozygous RYR1 mutant' vs 'RYR1 wild type' in 'embryonic day 14.5'developmental stage, genotypeMicroarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels
Adjusted p-valueLog2-fold change
9.7109 × 10-3-2.4
Myot'miR-1-133a_FGFR1_tKO' vs 'wild type genotype'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
3.3761 × 10-22.4
Myot'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
1.2327 × 10-52.3
Myot'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
2.28 × 10-4-2.3
Myot'homozygous RYR1 mutant' vs 'RYR1 wild type' in 'embryonic day 14.5'developmental stage, genotypeMicroarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels
Adjusted p-valueLog2-fold change
3.0258 × 10-2-2.3
Myot'miR-1-133a_OSMR_tKO' vs 'wild type genotype'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
5.2943 × 10-42.2
Myot'p150 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA'RNA interferenceRNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells
Adjusted p-valueLog2-fold change
1.1845 × 10-32.2
Myot'p60 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA'RNA interferenceRNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells
Adjusted p-valueLog2-fold change
2.1306 × 10-32.2
Myot'Id3 knockout' vs 'wild type' in 'Tet+CD24-CD44+NK1.1- Invariant natural killer T'cell type, genotypeEssential functions for ID proteins at multiple checkpoints in natural killer T cell development
Adjusted p-valueLog2-fold change
1.6546 × 10-2-2.2
Myot'miR-1-133a_dKO' vs 'wild type genotype'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
3.0037 × 10-2-2.2
Myot'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.3878 × 10-22.1
Myot'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
2.6175 × 10-2-2.1
Myot'ERRalpha null mutant' vs 'wild type genotype'genotypeTranscription profiling of mouse hearts from mutants lacking estrogen-related receptor alpha (ERRalpha), a nuclear receptor
Adjusted p-valueLog2-fold change
1.3227 × 10-3-2
Myot'chemical hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo.
Adjusted p-valueLog2-fold change
3.5218 × 10-22
Myot'CFTR-; female; BALB' vs 'wild type; female; BALB'genotype, sex, strainTranscription profiling of lung from a mouse model of cystic fibrosis fromB6 and Balb strains vs wild type littermates to determine strain specific differences
Adjusted p-valueLog2-fold change
1.6381 × 10-21-1.9
Myot'AAV9-Ccnt1;Myh6-cre;LSL-R26CAG-c-MycERT2/+' vs 'AAV9-Ccnt1;LSL-R26CAG-c-MycERT2/+'genotypeRNA-seq of purified cardiomocytes from adult mice (+/- AAV-CCNT1) 4 hours post MycER activation compared controls.
Adjusted p-valueLog2-fold change
6.0055 × 10-3-1.9
Myot'Tgfbr2fl/fl;Wnt1-Cre' vs 'wild type'genotypeGene expression profiling of Tgfbr2 mutant mouse models of cleft palate
Adjusted p-valueLog2-fold change
5.1895 × 10-24-1.8
Myot'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
1.327 × 10-71.8
Myot'Gata4+/-' vs 'wild type genotype' in 'TAC-mediated heart pressure overload'environmental stress, genotypeTranscription profiling of hearts from mice heterozygous for Gata4 mutation (G4D) to investigate the significance of Gata4 in regulating postnatal heart function and in regulating the hypertrophic response of the heart to pathological stress.
Adjusted p-valueLog2-fold change
8.8787 × 10-5-1.8
Myot'heart-specific Mdm2 knockout; 14 day' vs 'heart-specific Mdm2 knockout; 7 day'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
1.5417 × 10-3-1.8
Myot'infarct and border region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
2.3499 × 10-31.8
Myot'H-Ras expression' vs 'wild type'phenotypeRNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls.
Adjusted p-valueLog2-fold change
4.3832 × 10-31.8
Myot'Fn14 knockout' vs 'wild type' in 'none'compound, genotypeChronic TNBS Colitis in the FN14 KO Mouse
Adjusted p-valueLog2-fold change
1.9042 × 10-21.8
Myot'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
2.3019 × 10-2-1.8
Myot'13 day; Alpha9 knockout' vs '13 day; wild type'age, genotypeTemporal profiling of gene expression in cochleae of wild type and alpha9 null mice
Adjusted p-valueLog2-fold change
3.9739 × 10-61.7
Myot'3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
9.8138 × 10-51.7
Myot'heart-specific Mdm2 knockout; 7 day' vs 'wild type phenotype'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
5.4684 × 10-41.7
Myot'cetrorelix; 3 milligram per kilogram' vs 'none' in 'inh-alpha/Tag transgenic'compound, genotypeNovel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice.
Adjusted p-valueLog2-fold change
9.531 × 10-41.6
Myot'UV' vs 'sham' in 'DMSO' at '6 hour'irradiate, timeTranscription profiling by array of mouse dorsal skin exposed to UV radiation vs controls in mice treated with DMSO or selective tyrosine kinase inhibitor AG825
Adjusted p-valueLog2-fold change
1.0906 × 10-31.6
Myot'doxorubicin; 15 milligram per kilogram; CHIP knockout' vs 'none; ; CHIP knockout'compound, genotypeExpression data from DOX(doxorubicin) -treated wild type or CHIP knockout C57BL/6J mice at day 5
Adjusted p-valueLog2-fold change
1.3372 × 10-31.6
Myot'doxorubicin; 15 milligram per kilogram; wild type' vs 'none; ; wild type'compound, genotypeExpression data from DOX(doxorubicin) -treated wild type or CHIP knockout C57BL/6J mice at day 5
Adjusted p-valueLog2-fold change
1.3105 × 10-4-1.5
Myot'metaphase II oocyte' vs 'germinal vesicle oocyte'cell typeTranscription profiling of mouse in vivo matured MII oocytes and fully in vivo grown germinal vesicle oocytes to identify gene transcripts linked to epigenetic reprogramming
Adjusted p-valueLog2-fold change
7.0083 × 10-41.5
Myot'heart-specific p53 knockout; 7 day' vs 'wild type phenotype'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
1.2483 × 10-21.5
Myot'48 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
4.0638 × 10-2-1.5
Myot'miR-1-1/133a-2KO' vs 'wild type genotype'genotypemiRNA-1/133a clusters regulate adrenergic control of cardiac repolarization
Adjusted p-valueLog2-fold change
4.3134 × 10-21.5
Myot'11beta-HSD knockout' vs 'wild type' in 'subcutaneous adipose tissue'genotype, organism partTranscription profiling of adipose tissue from mesenteric and subcutaneous depots from 11beta-HSD1 knockout and wild type mice
Adjusted p-valueLog2-fold change
4.3955 × 10-21.5
Myot'brown adipose tissue' vs 'white adipose tissue' in 'high fat diet; 30 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
2.5791 × 10-191.4
Myot'Tcf7l2 knockout' vs 'wild type genotype' in 'adult'developmental stage, genotypeEffect of Tcf7l2 Knockout in the development and identity of Mouse brain Thalamus at embryonic stage E18.5 and P60
Adjusted p-valueLog2-fold change
2.2171 × 10-81.4
Myot'1810027O10Rik knockout; lung' vs 'wild type genotype; lung'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
6.936 × 10-5-1.4
Myot'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
3.2043 × 10-41.4
Myot'heart-specific p53 and Mdm2 knockout; 1 day' vs 'wild type phenotype'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
6.839 × 10-31.4
Myot'dextran sodium sulphate induced colitis' vs 'normal' in 'L-Arginine'compound, diseaseTranscription profiling by array of murine colon tissue after exposure to 4% dextran sodium sulphate (DSS) for 6 days followed by 4 days of water or 1% L-arginine to study the effect of L-arginine on DSS-induced colitis
Adjusted p-valueLog2-fold change
1.8211 × 10-21.4
Myot'Gata4+/-' vs 'wild type genotype' in 'no pressure overload'environmental stress, genotypeTranscription profiling of hearts from mice heterozygous for Gata4 mutation (G4D) to investigate the significance of Gata4 in regulating postnatal heart function and in regulating the hypertrophic response of the heart to pathological stress.
Adjusted p-valueLog2-fold change
1.4176 × 10-51.3
Myot'3 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
3.5515 × 10-51.3
Myot'6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
2.3614 × 10-2-1.3
Myot'Mettl6 knockout clone D1' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
1.0357 × 10-51.2
Myot'Aire knock out' vs 'wild type'genotypeTranscription profiling by array of mouse thymic medullary epithelial cells mutant for Aire
Adjusted p-valueLog2-fold change
5.9668 × 10-51.2
Myot'alpha-amanitin; maternal Ring1-Rnf+' vs 'none; maternal Ring1-Rnf+'compound, genotypePolycomb function during oogenesis is required for mouse early embryonic development (2-cell embryos)
Adjusted p-valueLog2-fold change
4.9363 × 10-41.2
Myot'acute DSS-induced colitis; 1x DSS, no recovery' vs 'none; none'clinical treatment, diseaseTranscription profiling by array of colon tissues isolated from mice with acute and chronic dextran sodium sulphate (DSS)-induced colitis
Adjusted p-valueLog2-fold change
3.1692 × 10-3-1.2
Myot'calorie restricted diet' vs 'normal diet' at '15 month'age, dietTranscription profiling by array of cochleae from mice fed a calorie-restricted diet
Adjusted p-valueLog2-fold change
8.3683 × 10-3-1.2
Myot'heart-specific p53 and Mdm2 knockout; 7 day' vs 'wild type phenotype'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
1.1177 × 10-41.1
Myot'Zbtb2 -/-' vs 'wild type genotype' in 'SerumLIF' at '2 day'genotype, growth condition, timeRNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.
Adjusted p-valueLog2-fold change
1.4873 × 10-4-1.1
Myot'homozygous Cav1.1 mutant' vs 'Cav1.1 wild type' in 'embryonic day 18.5'developmental stage, genotypeMicroarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels
Adjusted p-valueLog2-fold change
2.3962 × 10-41.1
Myot'Smad4 mutant' vs 'control'genotypeGene expression profile of Myf5-Cre;Smad4flox/flox mutant
Adjusted p-valueLog2-fold change
9.5917 × 10-4-1.1
MyotSynacthen vs sodium chloride controlcompoundTranscription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses.
Adjusted p-valueLog2-fold change
3.7637 × 10-3-1.1
Myot'left ventricle' vs 'right ventricle' in 'embryonic day 9.5'developmental stage, organism partTranscriptional Atlas of Cardiogenesis Maps Congenital Heart Disease Interactome
Adjusted p-valueLog2-fold change
2.0045 × 10-2-1.1
Myot'miR-1-2/133a-1KO' vs 'wild type genotype'genotypemiRNA-1/133a clusters regulate adrenergic control of cardiac repolarization
Adjusted p-valueLog2-fold change
2.033 × 10-21.1
Myot'TAC surgery' vs 'sham surgery' in 'C57BL/6N'strain, treatmentTranscription profiling of left ventricular myocardium after sham or TAC surgery in BL/6N and BL/6J mice
Adjusted p-valueLog2-fold change
4.4603 × 10-20-1
Myot'Titin-N2B knockout' vs 'wild type genotype' in 'none'RNA interference, genotypeHeart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF)
Adjusted p-valueLog2-fold change
1.5487 × 10-3-1
Myot'high fat diet' vs 'normal'dietGene expression changes in Ahnak knockout mice
Adjusted p-valueLog2-fold change
2.8135 × 10-3-1
Myot'Alk5 fl/fl; Wnt1-Cre' vs 'control'genotypeGene expression profiling of the tongue bud from Alk5 mutant mouse models
Adjusted p-valueLog2-fold change
1.6132 × 10-2-1
Myot'acute graft vs. host disease' vs 'normal'compound, diseaseTranscription profiling by array of murine thymus medulla in the absence and presence of acute graft-versus-host disease
Adjusted p-valueLog2-fold change
3.1451 × 10-21
Myot'6 week' vs '0 week'timeTranscription profiling by array of mouse colon tissues with T cell transfer-induced colitis at week 0, 2, 4 and 6 post-transfer
Adjusted p-valueLog2-fold change
3.5106 × 10-21
Myot'15 day' vs '0 day'ageTime course analysis of the cardiac transcriptome in the neonatal period
Adjusted p-valueLog2-fold change
4.9936 × 10-2-1
Myot'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout'compound, genotypeLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Synonym
5530402I04Rik, Ttid
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
5224378, 4643915, 5101926, 1418155_at, 4640679, 5225474, 162959_i_at, 5407167, 5160189, ILMN_2444217, 5340560, 4562521, 17350267, 5388369, 5541586, A_51_P488368, 4822358, 10455461, A_55_P1960192, 4493927, ILMN_2478649