-17.3 | | Lox | 'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-11.7 | | Lox | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
8.1 | | Lox | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
-7.2 | | Lox | 'induced neural stem cell' vs 'mouse embryonic fibroblast cell' | cell type | Gene expression profile of mouse induced neural stem cells |
-7.1 | | Lox | 'Mkl1-RFP with a mutated SRF-interaction site' vs 'full length Mkl1-RFP' | genotype | Transcription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1) |
7 | | Lox | '10 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-6.1 | | Lox | 'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-5.9 | | Lox | '70 week' vs '6 week' in 'none; none; | age, irradiate | Pericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence |
-5.5 | | Lox | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
5.3 | | Lox | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
5.2 | | Lox | 'dexamethasone; 1 micromolar' vs 'none' | compound | RNA-seq of primary hepatocytes treated with GR and PPARalpha agonists in the presence of LPS |
-5.2 | | Lox | 'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
5.2 | | Lox | 'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
-5.1 | | Lox | '5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a' | genotype, time | RNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating |
4.9 | | Lox | 'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
4.5 | | Lox | 'lipopolysaccharide' vs 'none' in 'bone marrow; wild type' | cell type, compound, genotype | Transcription profiling by high throughput sequencing of spleens of GPR34 knockout and wild type mice |
4.5 | | Lox | 'status epilepticus' vs 'none' in 'microglia; soticlestat; 30 milligram per kilogram' | cell type, compound, disease | RNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment |
4.4 | | Lox | 'infarct and border region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
4.3 | | Lox | 'heart-specific p53 and Mdm2 knockout; 7 day' vs 'heart-specific p53 and Mdm2 knockout; 1 day' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
4.3 | | Lox | 'status epilepticus' vs 'none' in 'microglia; none' | cell type, compound, disease | RNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment |
4.1 | | Lox | 'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'wild type genotype' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
4.1 | | Lox | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
4.1 | | Lox | 'Id2_Id3_double knockout' vs 'wild type' in 'CD4+TCRb+CD8– cell; thymus' | cell type, genotype, organism part | Transcription profiling by high throughput sequencing of Id-proteins (Id2 and Id3) gene knockout cells |
-4.1 | | Lox | 'neuron' vs 'differentiating progenitor' | cell type | Transcription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line |
4 | | Lox | 'colitis' at '8 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
4 | | Lox | 'M-CSF and FSL-1' at '6 day' vs 'none' at '0 day' | compound, time | Microarray profiling of polyploid macrophage progeny |
4 | | Lox | 'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
4 | | Lox | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
3.9 | | Lox | 'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
3.9 | | Lox | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'biliary-derived proliferative ducts (bilDP)' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
3.9 | | Lox | 'heart-specific Mdm2 knockout; 14 day' vs 'heart-specific Mdm2 knockout; 7 day' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
3.9 | | Lox | 'infarct and border region of left ventricle 5 days post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; MRL/MpJ' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
-3.9 | | Lox | '10 nanogram per milliliter; TGF-beta1' vs 'none' in 'common dendritic progenitor' at '24 hour' | cell type, compound, time | Dynamic Gene Expression Response to TGF-b Stimulation in Multipotent Progenitors and Common Dendritic Cell Progenitors |
-3.9 | | Lox | 'polysomal RNA; HRasV12 and c-Myc overexpression and Eif4e wild type' vs 'polysomal RNA; wild type' | fraction, genotype | Redefining the role of eIF4E dose in development, cancer, and protein synthesis |
3.8 | | Lox | 'dexamethasone (1 μM) and GW7647 (0.5 μM)' vs 'none' | compound | RNA-seq of primary hepatocytes treated with GR and PPARalpha agonists in the presence of LPS |
3.8 | | Lox | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
3.8 | | Lox | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-3.8 | | Lox | 'R1_Pax4+' at '0 day' vs 'wild type' at '0 day' | phenotype, time | Transcription profiling of mouse wild type R1 and cells expressing Pax4 following induction of pacreatic differentitation |
3.7 | | Lox | 'M-CSF and FSL-1' at '3 day' vs 'none' at '0 day' | compound, time | Microarray profiling of polyploid macrophage progeny |
3.7 | | Lox | '5 nanogram per milliliter; TGFbeta1' vs 'none' at '24 hour' | compound, time | Transcription profiling by array of mouse hepatocytes following treatment with growth factor beta 1 in a time series |
-3.7 | | Lox | '10 nanogram per milliliter; TGF-beta1' vs 'none' in 'common dendritic progenitor' at '12 hour' | cell type, compound, time | Dynamic Gene Expression Response to TGF-b Stimulation in Multipotent Progenitors and Common Dendritic Cell Progenitors |
3.7 | | Lox | 'transplanted secondary tumors' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
-3.7 | | Lox | 'heart-specific p53 and Mdm2 knockout; 1 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
3.7 | | Lox | 'ulcer' vs 'distant normal tissue' in 'wild type genotype' | genotype, sampling site, time | Intestinal ulcers from biopsy-wounded wild-type and Bmp4-overexpressing mice |
3.6 | | Lox | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
3.6 | | Lox | 'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
3.6 | | Lox | 'unilateral ureteral obstruction' vs 'sham' in 'wild type' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
3.5 | | Lox | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
-3.5 | | Lox | 'total RNA; HRasV12 and c-Myc overexpression and Eif4e wild type' vs 'total RNA; wild type' | fraction, genotype | Redefining the role of eIF4E dose in development, cancer, and protein synthesis |
-3.4 | | Lox | 'heart-specific Mdm2 knockout; 7 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
-3.4 | | Lox | 'heart-specific p53 knockout; 28 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
3.4 | | Lox | 'ulcer' vs 'distant normal tissue' in 'Bmp4 overexpression' | genotype, sampling site, time | Intestinal ulcers from biopsy-wounded wild-type and Bmp4-overexpressing mice |
3.3 | | Lox | 'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
3.3 | | Lox | 'confluent monolayer on collagen' at '1 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-3.3 | | Lox | 'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
-3.3 | | Lox | 'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells' | age, cell type | Transcriptional profiling of nascent and mature pancreatic beta cells |
3.3 | | Lox | '7 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-3.3 | | Lox | 'heart-specific p53 knockout; 7 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
-3.3 | | Lox | 'carcinoma' vs 'normal' | disease | Gene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse |
3.2 | | Lox | 'SR-BI-/- apoE-/-' vs 'control' in '43 day; Chow diet' | age, diet, genotype | Expression data from the hearts of a mouse model of spontaneous myocardial infarction |
3.2 | | Lox | 'PS2APP transgenic' vs 'non transgenic' in 'microglia cell' at '13 month' | age, cell type, genotype | Transcription profiling by high throughput sequencing of astrocytes, microglial and neuronal cells from an Alzheimer's mouse model |
3.2 | | Lox | 'Foxd3 knockout' vs 'control' | phenotype | Expression data from embryonic stem cells differentiation |
3.1 | | Lox | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
3.1 | | Lox | 'PTEN null, P53-/-' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
-3.1 | | Lox | '10 nanogram per milliliter; TGF-beta1' vs 'none' in 'common dendritic progenitor' at '8 hour' | cell type, compound, time | Dynamic Gene Expression Response to TGF-b Stimulation in Multipotent Progenitors and Common Dendritic Cell Progenitors |
3.1 | | Lox | 'expanded on HUVEC and m5GF in the presence of mD1R for 7 days' vs 'control' | treatment | Expression data from cultured c-Kit+Sca-1+Lin- (KSL)cells |
3.1 | | Lox | 'non-infarct region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as non-infarct tissue in post-myocardial infarction hearts; C57BL/6J' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
3 | | Lox | 'non-infarct region of left ventricle 5 days post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as non-infarct tissue in post-myocardial infarction hearts; MRL/MpJ' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
3 | | Lox | 'SOD1-G93A transgenic' vs 'wild type' at 'day 130/end-stage' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
3 | | Lox | 'RA839; Nrf2 knockout' vs 'RA839; wild type genotype' | RNA interference, compound, genotype | Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling |
2.9 | | Lox | '3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
2.9 | | Lox | 'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
2.9 | | Lox | 'macrophage; lipopolysaccharide stimulated' vs 'macrophage; unstimulated' | cell type, treatment | Gene expression profile of GM-CSF derived bone marrow dendritic cell subsets after LPS stimulation |
2.9 | | Lox | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
2.8 | | Lox | 'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'CD36 knockout' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
2.8 | | Lox | 'Sall4 homozygous knockout' vs 'wild type genotype' | genotype | RNA-Seq of Sall4 mutants in mouse embryonic stem cells |
2.8 | | Lox | 'Mettl6 knockout clone D1' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
2.8 | | Lox | 'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal' | disease | Transcription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma |
2.8 | | Lox | 'transverse aortic constriction' vs 'sham transverse aortic constriction' | treatment | Transcriptional profiling of mouse heat left ventricle after dfferential cardiac remodeling in preload versus afterload. |
2.8 | | Lox | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '7 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
2.7 | | Lox | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-2.7 | | Lox | 'SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2.7 | | Lox | '730 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
2.6 | | Lox | 'liver-specific Cnot1 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
2.6 | | Lox | 'Trichuris muris' vs 'control' in 'non wormy; caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
-2.6 | | Lox | 'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-2.6 | | Lox | 'Ink4a/Arf-/-; EGFRvIII' vs 'wild type genotype' in 'co-culture' | genotype, growth condition | RNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions |
-2.6 | | Lox | 'PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2.6 | | Lox | '90 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
2.5 | | Lox | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-2.5 | | Lox | 'MEF; transduced with MyoD lentivirus' vs 'MEF; control' | cell line, treatment | Genetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling] |
2.5 | | Lox | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.5 | | Lox | 'cardiac-specific constitutive expression of an activated Akt (caAkt)' vs 'wild type genotype' | genotype | Transcription profiling by array of cardic ventricle tissues from mice with cardiac-specific constitutive expression of an activated Akt (caAkt) and wild-type controls to test whether Akt activation contributes to mitochondrial dysfunction in pathological cardiac hypertrophy |
2.5 | | Lox | 'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
2.5 | | Lox | '5XFAD transgenic' vs 'wild type' | genotype | Transcription profiling by array of microglia purified from wild type and TREM2 deficient microglia in a mouse model of Alzheimer's disease |
2.5 | | Lox | 'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, and PLAT knock-out mice |
2.5 | | Lox | 'unilateral ureteral obstruction' vs 'sham' in 'TIMP2 -/-' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
-2.5 | | Lox | '365 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
2.4 | | Lox | 'Irx3 knockout' vs 'control' at '7 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
2.4 | | Lox | 'chronic pancreatitis' vs 'control' | disease | Pancreatic gene expression associated with cerulein induced chronic pancreatitis in mice |
2.4 | | Lox | 'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
2.4 | | Lox | 'confluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-2.4 | | Lox | 'inhibition of BRD4 with JQ1' vs 'DMSO' | treatment | Expression Data For BRD4 Inhibition |
2.4 | | Lox | 'confluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-2.4 | | Lox | 'wild type; mature luminal' vs 'wild type; MaSC/basal' | cell type, genotype | Expression data from sorted control and Pygo2-null mouse mammary stem/basal cells |
-2.4 | | Lox | 'pkd1 knockout' vs 'wild type' in 'absence of fluid flow' | genotype, stimulus | Transcription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow |
2.4 | | Lox | 'SARS coronavirus MA15' vs 'none' at '7 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
2.4 | | Lox | 'tumor' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
-2.4 | | Lox | '180 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-2.4 | | Lox | '60 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
2.4 | | Lox | 'vehicle control; Nrf2 knockout' vs 'vehicle control; wild type genotype' | RNA interference, compound, genotype | Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling |
2.3 | | Lox | 'follicle stimulating hormone and epidermal growth factor' vs '293H control medium' | growth condition | Transcription profiling by array of mouse cumulus cells after culture with growth differentiation factor 9 or follicle stimulating hormone and epidermal growth factor |
-2.3 | | Lox | 'Gprc5a knockout' vs 'control' | genotype | Gene expression profile of lung epithelial cells cultured from normal tracheas of Gprc5a knockout and wild-type mice |
2.3 | | Lox | 'PAI1 knockout; SARS MA15; 7 day' vs 'PAI1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-2.3 | | Lox | 'CD47 knockdown; cell from embryoid body-like cluster’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
2.3 | | Lox | 'heart; 3 day' vs 'heart; 0 day' | organism part, time | Expression data from mouse tissue Angiotensin II treated for 0,1,3,7days |
-2.3 | | Lox | 'miR-1-133a_OSMR_tKO' vs 'miR-1-133a_dKO' | compound, genotype | Repression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart |
-2.3 | | Lox | 'polysomal RNA; HRasV12 and c-Myc overexpression and Eif4e heterozygous knockout' vs 'polysomal RNA; wild type' | fraction, genotype | Redefining the role of eIF4E dose in development, cancer, and protein synthesis |
-2.3 | | Lox | '19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day' | cell line, growth condition, time | Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines |
2.2 | | Lox | 'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
2.2 | | Lox | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
2.2 | | Lox | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-2.2 | | Lox | 'Mkl1-RFP with a deletion of the SAP domain' vs 'full length Mkl1-RFP' | genotype | Transcription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1) |
2.2 | | Lox | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-2.2 | | Lox | 'chemical hypoxia' vs 'control' | growth condition | Comparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo. |
-2.2 | | Lox | 'Lkb1 -/- Pten-/-' vs 'wild type' | genotype | Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells |
-2.2 | | Lox | 'Ink4a/Arf-/-; EGFRvIII' vs 'wild type genotype' in 'separate' | genotype, growth condition | RNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions |
-2.2 | | Lox | 'UO126; 0.2 milligram per kilogram; miR-1-133a_dKO' vs 'miR-1-133a_dKO' | compound, genotype | Repression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart |
2.2 | | Lox | '5 day; Ad-VEGF-A164' vs '0 day; control' | time, treatment | Transcription profiling by array of stromal-based signatures for the classification of gastric cance |
-2.1 | | Lox | 'cut nerve; 7 day' vs 'none' | injury, protocol, time | Changes in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury |
2.1 | | Lox | 'phenylephrine; 30 milligram per kilogram per day' vs 'vehicle' | compound | RNA-seq of myocytes from mice treated in vivo for 3 days with vehicle, angiotensin II, or phenylephrine |
2.1 | | Lox | 'Helicobacter hepaticus' vs 'none' in 'wild type phenotype' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
2.1 | | Lox | 'Plasmodium berghei ANKA' at '7 day' vs 'none' at '0 day' in 'none' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
-2.1 | | Lox | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '30 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
2.1 | | Lox | 'clear cell sarcoma; Rosa26CreER' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
2.1 | | Lox | 'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
2.1 | | Lox | 'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
2.1 | | Lox | 'Mst1/2 knockout' vs 'control' | genotype | Microarray of Mst1/2 deleted epithelial cells from E18.5 mouse lungs |
2.1 | | Lox | 'p60 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA' | RNA interference | RNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells |
2.1 | | Lox | 'TIMP1 knockout; SARS MA15; 4 day' vs 'TIMP1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-2.1 | | Lox | 'miR-1-133a_FGFR1_tKO' vs 'miR-1-133a_dKO' | compound, genotype | Repression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart |
2.1 | | Lox | 'uterine-specific Tsc2-null' vs 'wild type' in '17beta-estradiol' | genotype, treatment | Transcription profiling by high throughput sequencing of uterine-specific Tsc2-null mice |
2.1 | | Lox | 'alphaMHC-Cre+/0;MAT1F/F' vs 'alphaMHC-Cre+/0;MAT1F/+' in '4 week' | age, genotype | Transcription profiling of mouse heart from cardiac-specific conditional knockout deletion of menage-a-trios-1 (MAT1) |
2.1 | | Lox | 'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
2.1 | | Lox | 'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
2.1 | | Lox | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
2.1 | | Lox | 'dextran sodium sulphate induced colitis' vs 'normal' in 'water' | compound, disease | Transcription profiling by array of murine colon tissue after exposure to 4% dextran sodium sulphate (DSS) for 6 days followed by 4 days of water or 1% L-arginine to study the effect of L-arginine on DSS-induced colitis |
2.1 | | Lox | 'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type' | genotype | Hepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice |
2.1 | | Lox | 'dextran sodium sulphate induced colitis' at '7 day' vs 'normal' at '0 day' | disease, time | Transcription profiling by array of Mus musculus colonic mucosa after treatment with dextran sodium sulphate (DSS) for 2 or 7 days which induces experimental colitis |
2 | | Lox | 'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
2 | | Lox | 'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
2 | | Lox | 'PAI1 knockout; SARS MA15; 4 day' vs 'PAI1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-2 | | Lox | 'wild type genoytpe; siRNA Keap1-1' vs 'wild type genotype; scrambled shRNA' | RNA interference, compound, genotype | Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling |
2 | | Lox | 'uterine-specific Tsc2-null' vs 'wild type' in 'intact' | genotype, treatment | Transcription profiling by high throughput sequencing of uterine-specific Tsc2-null mice |
1.9 | | Lox | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.9 | | Lox | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '14 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.9 | | Lox | 'tamoxifen; autosomal dominant polycystic kidney disease' vs 'none; normal' | compound, disease, time | Expression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC |
1.9 | | Lox | 'wild type genotype; SARS MA15; 7 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1.9 | | Lox | 'transgenic' vs 'wild type' in '121 day; 129Sv' | age, genotype, strain | Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models |
1.9 | | Lox | '6 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
1.9 | | Lox | 'Mettl6 knockout clone G6' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
1.9 | | Lox | 'smoke; 3000 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
1.9 | | Lox | 'Crx knockout' vs 'control' at '6 zeitgeber' | genotype, time | Transcriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20 |
1.9 | | Lox | 'SARS coronavirus MA15' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
1.9 | | Lox | 'Plasmodium chabaudi infection' vs 'no infection' in 'adjuvant only' | infect, treatment | Protective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase |
-1.9 | | Lox | 'spontaneous lung tumor' vs 'normal' | disease state, disease | Transcription profiling by array of spontaneous lung tumors in mice to compare to human non-small cell lung cancer |
1.9 | | Lox | 'p150 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA' | RNA interference | RNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells |
-1.9 | | Lox | 'SARS coronavirus MA15 nsp16 -/-' vs 'SARS coronavirus MA15' at '7 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
1.9 | | Lox | 'Gata6 knockout' vs 'wild type' | phenotype | Global gene expression in the adult Gata6 null mouse pancreas |
1.9 | | Lox | 'acute DSS-induced colitis; 1x DSS, no recovery' vs 'none; none' | clinical treatment, disease | Transcription profiling by array of colon tissues isolated from mice with acute and chronic dextran sodium sulphate (DSS)-induced colitis |
1.9 | | Lox | 'Trypanosoma brucei TREU927' vs 'uninfected' | infect | Transcription profiling by array of spleens from mice infected with different Trypanosoma brucei strains |
1.9 | | Lox | 'untreated; Csf2rb-/-' vs 'untreated; wild type' | clinical history, genotype | Mouse GM-CSF-related alveolar macrophage genome-wide expression data |
-1.8 | | Lox | 'interferon gamma' vs 'dexamethasone; 100 nanomolar' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
1.8 | | Lox | 'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '2 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
-1.8 | | Lox | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '10 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.8 | | Lox | 'Porphyromonas gingivalis; hyperlipidemia' vs 'normal' | infect, phenotype | hyperlipidemia impaired innate response |
1.8 | | Lox | 'Pkhd1Cre; Pkd2 F/F' vs 'wild type' | genotype | Next Generation Sequencing of PKD2 mutant mice kidneys |
1.8 | | Lox | 'SARS coronavirus MA15' vs 'none' at '2 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
1.8 | | Lox | 'Mycobacterium tuberculosis; DBA/2J congenic; 70 day' vs 'control; DBA/2J congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
-1.8 | | Lox | 'apolipoprotein E knockout' vs 'wild type' in 'high fat' | diet, genotype | Gene expression from epidydimal fat pad |
1.8 | | Lox | 'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 2 month exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
1.8 | | Lox | 'STAT1 -/-' vs 'wild type genotype' in 'SARS coronavirus MA15' at '9 day' | genotype, infect, time | Transcriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds |
-1.8 | | Lox | 'postnatal day 21; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-1.8 | | Lox | 'dox-induced over-expression of oncogenes for 5 days' vs 'untreated control' | phenotype | Temporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice |
1.8 | | Lox | 'UV' vs 'sham' in 'DMSO' at '6 hour' | irradiate, time | Transcription profiling by array of mouse dorsal skin exposed to UV radiation vs controls in mice treated with DMSO or selective tyrosine kinase inhibitor AG825 |
1.8 | | Lox | '6 day' vs '0 day' | time | Transcription profiling by array of mouse colon tissues under dextran sodium sulphate induction for 2, 4 and 6 days against uninduced controls at day 0 |
1.8 | | Lox | 'NEMO-TNFR1 double knockout' vs 'wild type' | genotype | TNFR1 controls apoptosis and chronic liver disease in hepatocyte-specific IKKγ (Nemo) mice. |
-1.8 | | Lox | '30 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
1.8 | | Lox | '20 day; Ad-VEGF-A164' vs '0 day; control' | time, treatment | Transcription profiling by array of stromal-based signatures for the classification of gastric cance |
-1.8 | | Lox | 'lipopolysaccharide; 10 nanogram per milliliter and PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.7 | | Lox | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
-1.7 | | Lox | 'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'endothelial cell; expressing AKT1' | cell type, growth condition, phenotype | Transcription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture |
1.7 | | Lox | 'S-(1,2-dichlorovinyl)-L-cysteine; 15 milligram per kilogram; renal injury; 1 week' vs 'none; normal' | compound, disease, time | Expression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC |
1.7 | | Lox | 'carotid body' vs 'adrenal medulla' | organism part | Expression profile of mouse carotid body and adrenal medulla [RNA-Seq] |
1.7 | | Lox | 'phosgene - carbonyl chloride' at '8 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanism of phosgene-induced lung injury |
1.7 | | Lox | 'phosgene - carbonyl chloride' at '24 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanism of phosgene-induced lung injury |
1.7 | | Lox | 'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
1.7 | | Lox | 'Influenza A virus' vs 'none' | infect | RNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals |
1.7 | | Lox | 'smoke; 1500 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
-1.7 | | Lox | 'postnatal >1 year; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
1.7 | | Lox | 'TIMP1 knockout; SARS MA15; 7 day' vs 'TIMP1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1.7 | | Lox | 'resiquimod; 100 microgram' vs 'none' in 'ovalbumin; A/J' | compound, stimulus, strain | Transcription profiling of mouse model of asthma reveals the effects of resiquimod treatment on the asthma transcriptome |
1.7 | | Lox | 'NEMO knockout' vs 'wild type' | genotype | TNFR1 controls apoptosis and chronic liver disease in hepatocyte-specific IKKγ (Nemo) mice. |
1.7 | | Lox | 'smoke; 3000 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
1.7 | | Lox | 'InsR, Igf1R double knockout' vs 'wild type' in 'postnatal day 5' | developmental stage, genotype | Transcriptional profiling by array of mouse wild-type and Insulin receptor (InsR)/Igf1 receptor (Igf1R) double knockout mutant Sertoli cells from testis at embryonic day E17.5 and Postnatal day 5 |
-1.7 | | Lox | 'Yin Yang 1 adipose tissue specific deletion' vs 'wild type phenotype' | phenotype | Brown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity [BAT] |
-1.7 | | Lox | 'total RNA; HRasV12 and c-Myc overexpression and Eif4e heterozygous knockout' vs 'total RNA; wild type' | fraction, genotype | Redefining the role of eIF4E dose in development, cancer, and protein synthesis |
1.7 | | Lox | 'H9; undifferentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; undifferentiated embryonic stem cell' at '0 day' | cell line, growth condition, time | Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines |
1.7 | | Lox | 'dexamethasone; 10 microgram per milliliter' vs 'none' | compound | RNA-seq of mouse sciatic peripheral nerve of injured mouse with implant: control (untreated) vs local delivery of MCC950 (NLRP3inh) vs standard FBR treatment dexamethasone (Dex). . |
1.6 | | Lox | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.6 | | Lox | 'wild type; SARS MA15; 2 day' vs 'wild type; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
-1.6 | | Lox | 'mutant MyoD expression' at '12 hour' vs 'wild type MyoD expression' at '0 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
-1.6 | | Lox | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '60 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.6 | | Lox | 'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '2 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
-1.6 | | Lox | 'mutant MyoD expression' at '24 hour' vs 'control' at '24 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
1.6 | | Lox | 'Bifidobacterium bifidum Z9' vs 'control' | infect | Transcription profiling by array of mouse dendritic cells after infection with Bifidobacterium bifidum and Lactobacillus acidophilus |
1.6 | | Lox | 'SARS coronavirus MA15 dORF6' vs 'none' at '2 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
1.6 | | Lox | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; MEF2C/D knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1.6 | | Lox | 'cardiotoxin; 10 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq comparison of fibro-adipogenic progenitors (FAPs) from wild type, mdx and cardiotoxin-injured mice |
1.6 | | Lox | 'cardiotoxin; 40 microliter' vs 'none' in 'wild type' at '12 day' | compound, genotype, time | Transcription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin |
-1.6 | | Lox | 'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell' | age, cell type, phenotype | Transcription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture |
1.6 | | Lox | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
1.6 | | Lox | 'trehalose dimycolated (TDM)' at '24 hour' vs 'phosphatidylglycerol (PG) control' at '24 hour' | stimulus, time | Transcription profiling by array of mouse bone marrow-derived macrophages stimulated by trehalose dimycolated (TDM) or phosphatidylglycerol (PG) control to study how mycobacterial TDM reprograms macrophage global gene expression |
1.6 | | Lox | 'epithelium-specific Apc knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1.6 | | Lox | 'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '4 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
1.6 | | Lox | 'beta1-adrenoceptor overexpression, Crem knockout' vs 'wild type' | genotype | Transcription profiling by array of CREM-knockout mice |
1.6 | | Lox | 'miR-1-133a_dKO' vs 'wild type genotype' | compound, genotype | Repression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart |
1.6 | | Lox | 'Alb-Cre;VHLf/f' vs 'Alb-Cre' | genotype | Transcription profiling by array of mice with liver-specific expression of hypoxia inducible factor, or inactivated von Hippel-Lindau tumor suppressor |
1.6 | | Lox | 'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'wild type' | compound, genotype | Laser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries |
-1.6 | | Lox | 'L-Arginine' vs 'water' in 'dextran sodium sulphate induced colitis' | compound, disease | Transcription profiling by array of murine colon tissue after exposure to 4% dextran sodium sulphate (DSS) for 6 days followed by 4 days of water or 1% L-arginine to study the effect of L-arginine on DSS-induced colitis |
1.6 | | Lox | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.6 | | Lox | 'normal skin; PKC alpha-/-' vs 'normal skin; wild type genotype' | clinical history, genotype | Altered dermal architecture in PKCα-/- skin |
1.6 | | Lox | 'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.5 | | Lox | 'mutant MyoD expression' at '24 hour' vs 'wild type MyoD expression' at '0 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
1.5 | | Lox | 'methionine- and choline-deficient, high fat diet mixed with 0.1% metformin' vs 'normal' | diet | Expression data from mouse liver treated with metformin |
1.5 | | Lox | 'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '2 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
1.5 | | Lox | 'methionine- and choline-deficient, high fat diet' vs 'normal' | diet | Expression data from mouse liver treated with metformin |
-1.5 | | Lox | '24 hour after induction of differentiation' vs 'induction of differentiation' | compound, sampling time point | Expression Profiling of Early Myogenesis - Affymetrix Dataset |
1.5 | | Lox | 'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
1.5 | | Lox | 'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
1.5 | | Lox | '3110043O21Rik knockout; liver' vs 'wild type genotype; liver' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
1.5 | | Lox | 'lipid nanoparticle complexed with ribonucleic acid expressing respiratory synctial virus F protein' vs 'phosphate buffered saline' | stimulus | Microarray analysis of mouse whole genome using self-amplifying messenger (SAM) RNA delivered with different formulations compared to controls |
1.5 | | Lox | 'infarct and border region of left ventricle 1 day post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
1.5 | | Lox | 'heart; 7 day' vs 'heart; 0 day' | organism part, time | Expression data from mouse tissue Angiotensin II treated for 0,1,3,7days |
-1.5 | | Lox | '10 nanogram per milliliter; TGF-beta1' vs 'none' in 'common dendritic progenitor' at '4 hour' | cell type, compound, time | Dynamic Gene Expression Response to TGF-b Stimulation in Multipotent Progenitors and Common Dendritic Cell Progenitors |
-1.5 | | Lox | '48 hour after induction of differentiation' vs 'induction of differentiation' | compound, sampling time point | Expression Profiling of Early Myogenesis - Affymetrix Dataset |
1.5 | | Lox | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
-1.5 | | Lox | 'RAW264.7 macrophage cell line; control' vs 'bone marrow macrophage; control' | cell type, growth condition | Transcription profiling of mouse bone marrow macrophages (BMM) compared to BMM co-cultured with 4T1.2 breast cancer cells, treated with tumour cell supernatant, or RAW macrophage cell line |
1.5 | | Lox | 'Cdx2 knockdown' vs 'scramble shRNA' in 'induced hepatocyte' | cell type, genotype | Dissecting engineered cell types and enhancing cell fate conversion via CellNet |
1.5 | | Lox | 'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
1.5 | | Lox | 'lipid nanoparticle alone' vs 'phosphate buffered saline' | stimulus | Microarray analysis of mouse whole genome using self-amplifying messenger (SAM) RNA delivered with different formulations compared to controls |
1.5 | | Lox | '2'-fucosyllactose supplementation' vs 'control' in '8 weeks post-ileocecal resection' | diet, treatment | Transcriptomic characterization of the impact of 2'-fucosyllactose supplementation on intestinal adaptation following ileocecal resection. |
1.5 | | Lox | 'doxorubicin; 15 milligram per kilogram; wild type' vs 'none; ; wild type' | compound, genotype | Expression data from DOX(doxorubicin) -treated wild type or CHIP knockout C57BL/6J mice at day 5 |
1.5 | | Lox | 'Pitx2-lacZ homozygous mutant' vs 'wild type genotype' | genotype | Transcription profiling by array of abdominal wall from heterozygous and homozygous Pitx2 mutant mouse embryos |
-1.5 | | Lox | '21 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
1.5 | | Lox | 'serrated polyp' vs 'normal surrounding (distal) cecum' | clinical information | Interplay of host microbiota, genetic perturbations, and inflammation promote local development of intestinal neoplasms in mice |
1.5 | | Lox | 'PLAT knockout; SARS MA15; 7 day' vs 'PLAT knockout; mock' | genotype, infect, time | SARS infection of C57BL6, and PLAT knock-out mice |
1.4 | | Lox | 'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1' | cell type, growth condition, phenotype | Transcription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture |
1.4 | | Lox | 'dexamethasone; 100 nanomolar' vs 'none' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
1.4 | | Lox | 'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'white adipose tissue' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1.4 | | Lox | '3 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
1.4 | | Lox | 'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1.4 | | Lox | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.4 | | Lox | 'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout' | compound, genotype, infect | 4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies |
1.4 | | Lox | 'collagen sandwich' at '1 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.4 | | Lox | 'wild type; SARS MA15; 7 day' vs 'wild type; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
1.4 | | Lox | 'Pkhd1Cre; Pkd2 F/F; miR-21null' vs 'wild type' | genotype | Next Generation Sequencing of PKD2 mutant mice kidneys |
1.4 | | Lox | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.4 | | Lox | 'TGF-beta1 5 nanograms per milliliter' vs 'none' | compound, dose | TGF-beta and BMP mediated gene expression in cultured sclerotome. |
1.4 | | Lox | '10 microgram; ovalbumin' vs 'none' in 'RAG null mutant' | compound, genotype | Transcription profiling by array of lungs from mice mutant for RAG after challenge with ovalbumin |
-1.4 | | Lox | 'Wnt1Cre Ezh2lox/lox' vs 'control' | genotype | Expression data from E11.5 mouse branchial arch 1 (BA1) - comparison between Ezh2lox/lox and Wnt1Cre Ezh2lox/lox embryos |
-1.4 | | Lox | '96 hour after induction of differentiation' vs 'induction of differentiation' | compound, sampling time point | Expression Profiling of Early Myogenesis - Affymetrix Dataset |
1.4 | | Lox | 'smoke; 1500 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
-1.4 | | Lox | 'embryoid body' vs 'embryonic stem cell' on 'Affymetrix GeneChip Array 430A 2.0' | developmental stage | Gene expression profile of J1 embryonic stem cells and J1 embryoid bodies |
-1.4 | | Lox | 'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
1.4 | | Lox | 'SARS coronavirus MA15 dORF6' vs 'none' at '4 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
-1.4 | | Lox | 'reduced expression of miR-25' vs 'wild type' | phenotype | Transcription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice |
1.4 | | Lox | '8 month; diabetes mellitus' vs '8 month; normal' | age, disease | Gene expression in OVE26 diabetic kidney during the development of nephropathy |
1.4 | | Lox | 'Plasmodium chabaudi infection' vs 'no infection' in 'vaccination' | infect, treatment | Protective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase |
1.4 | | Lox | 'heart; 1 day' vs 'heart; 0 day' | organism part, time | Expression data from mouse tissue Angiotensin II treated for 0,1,3,7days |
1.4 | | Lox | 'AKR/J mice co-housed 1:1 with C57BL/6 mice' vs 'AKR/J mice in single housing' | growth condition | Gut microbiota and gallstone formation - cohousing study |
1.4 | | Lox | '4 day' vs '1 day' in 'influenza A infected DBA/2J' | disease, strain, time | Transcription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection |
1.4 | | Lox | 'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout' | compound, genotype | Laser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries |
1.4 | | Lox | 'Reg3beta knockout' vs 'wild type' in 'tissue from remote zone' | clinical information, genotype | myocardial infarction in Reg3beta knock-out mice |
-1.3 | | Lox | 'Duchenne muscular dystrophy' vs 'normal' | disease | RNA-seq comparison of immortalised myoblasts from dystrophic and WT mice |
-1.3 | | Lox | 'PPARgamma2 overexpression' vs 'empty vector' at '10 day' | genotype, time | Transcription profiling by array of mouse NIH3T3 cells over-expressing PPARg pr EBF1 over time |
-1.3 | | Lox | 'samarium doped cerium oxide nanoparticles; 1 day differentiated; 25 microgram per milliliter' vs 'none; 1 day differentiated' | compound, developmental stage | RNA-seq of C17.2 neuronal progenitor cells exposed to cerium oxide nanoparticles during cell differentiation |
-1.3 | | Lox | 'Drosha -/-' vs 'wild type genotype' | genotype | RNA-seq of mouse ES cells with conditional Drosha knockout against wild type controls to identify pri-miRNAs |
1.3 | | Lox | 'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
-1.3 | | Lox | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'inguinal fat pad' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
1.3 | | Lox | 'Lactobacillus acidophilus NCFM and Bifidobacterium bifidum Z9' vs 'control' | infect | Transcription profiling by array of mouse dendritic cells after infection with Bifidobacterium bifidum and Lactobacillus acidophilus |
1.3 | | Lox | 'non-infarct region of left ventricle 1 day post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as non-infarct tissue in post-myocardial infarction hearts; C57BL/6J' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
1.3 | | Lox | 'Rev-erb alpha knockout' vs 'wild type' | genotype | Transcription profiling by array of epididymal white adipose tissue of Rev-erb alpha knockout mouse |
1.3 | | Lox | 'SARS coronavirus MA15' vs 'none' at '2 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
1.3 | | Lox | 'collagen sandwich' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-1.3 | | Lox | 'pkd1 knockout' vs 'wild type' in 'presence of fluid flow' | genotype, stimulus | Transcription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow |
1.3 | | Lox | 'phosgene - carbonyl chloride' at '4 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanism of phosgene-induced lung injury |
1.3 | | Lox | 'mdx' vs 'wild type' in 'postnatal day 56' | developmental stage, genotype | Transcription profiling of mouse hindlimb muscle, comparison of wild type and mdx mice, 7 to 112 Day |
1.3 | | Lox | 'phosgene - carbonyl chloride' at '12 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanism of phosgene-induced lung injury |
-1.3 | | Lox | '45 percent caloric restriction' vs 'control' | diet | Gene expression profile from short-term caloric restriction in mouse adipose tissue |
1.3 | | Lox | 'Yin Yang 1 (YY1) knockout' vs 'wild type' | genotype | Expression data from mouse skeletal muscle |
1.3 | | Lox | 'infarct and border region of left ventricle 1 day post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; MRL/MpJ' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
-1.3 | | Lox | 'wild type genoytpe; siRNA Keap1-2' vs 'wild type genotype; scrambled shRNA' | RNA interference, compound, genotype | Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling |
-1.3 | | Lox | '10 nanogram per milliliter; TGF-beta1' vs 'none' in 'multipotent progenitor' at '24 hour' | cell type, compound, time | Dynamic Gene Expression Response to TGF-b Stimulation in Multipotent Progenitors and Common Dendritic Cell Progenitors |
-1.3 | | Lox | 'V6.5; embryonic stem cell’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
1.3 | | Lox | 'Mycobacterium tuberculosis; DBA/2J congenic; 30 day' vs 'control; DBA/2J congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.3 | | Lox | 'low-protein/high-carbohydrate diet' vs 'western diet' | diet | Gene expression analysis of subcutaneous adipose tissue in mice fed with a low-protein/high carbohydrate diet |
-1.3 | | Lox | 'Hox6 mutant' vs 'wild type' | genotype | Comparison of Hox6 mutant and control E12.5 mouse pancreas |
1.3 | | Lox | 'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1.3 | | Lox | 'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 2 month exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
1.3 | | Lox | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.3 | | Lox | 'Timp3-/-' vs 'wild type genotype' | genotype | Transcription profiling by array of kidneys from diabetic wild type and T3-/- mice |
1.3 | | Lox | 'shunt' vs 'sham shunt' | treatment | Transcriptional profiling of mouse heat left ventricle after dfferential cardiac remodeling in preload versus afterload. |
1.3 | | Lox | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
1.2 | | Lox | 'dexamethasone; 100 nanomolar; interferon gamma' vs 'none' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
1.2 | | Lox | 'Setd5 homozygous (null) knockout' vs 'Setd5 heterozygous knockout' | genotype | Transcriptional profiling of Setd5 heterozygous and knockout mouse embryonic stem cells |
1.2 | | Lox | '6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
1.2 | | Lox | 'phosgene - carbonyl chloride' at '8 hour' vs 'air' at '8 hour' | compound, time | Transcription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanism of phosgene-induced lung injury |
1.2 | | Lox | 'phosgene - carbonyl chloride' at '24 hour' vs 'air' at '24 hour' | compound, time | Transcription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanism of phosgene-induced lung injury |
1.2 | | Lox | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.2 | | Lox | 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 0 day' | cell type, compound, time | Drug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs |
-1.2 | | Lox | 'Gata3 knock out' vs 'wild type' | genotype | Transcription profiling by array of Gata3 knock-out mice |
1.2 | | Lox | 'Foxd1 null' vs 'wild type' | genotype | Gene expression comparison of E14.5 Foxd1 null and wild type kidneys |
1.2 | | Lox | 'hyperoxia' vs 'control' in 'male' | sex, stimulus | Transcription profiling by array of lung tissues from wild-type male and female C56BL/6J mice either maintained in room air or exposed to hyperoxia (FiO2>95%) for 48 hours |
1.2 | | Lox | '10 Gy Gray; x-ray' vs 'none' in 'tumor and stromal cell' | cell type, irradiate | RNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated |
-1.2 | | Lox | '14 day' vs '7 day' vs 'anti-mPDL1; anti-mCTLA4; 10 milligram per kilogram' | compound, time | RNAseq of tumor samples from CT26 syngeneic mouse treated with a PD-L1 and CTLA-4 immunotherapy combination |
-1.2 | | Lox | 'Ptenf/f x CCSPiCre' vs 'wild type' at '7 month' | age, genotype | ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [expression] |
1.2 | | Lox | 'MFP2 knockout' vs 'wild type' | genotype | Defining the microglia transcriptome in multifunctional protein-2 deficient mice |
-1.2 | | Lox | 'normobaric hypoxia' vs 'control' | growth condition | Comparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo. |
-1.2 | | Lox | '21 percent oxygen, 37 degree Celsius, no serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
1.2 | | Lox | 'trinitrobenzene sulfonic acid' vs 'none' in 'wild type' | compound, genotype | Chronic TNBS Colitis in the FN14 KO Mouse |
1.2 | | Lox | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '4 day' | genotype, infect, time | SM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice |
1.2 | | Lox | '5 Gray; X-radiation' vs 'none' at '30 week' | irradiate, time | Senescence gene signature of radiation fibrosis |
-1.2 | | Lox | '144 hour after induction of differentiation' vs 'induction of differentiation' | compound, sampling time point | Expression Profiling of Early Myogenesis - Affymetrix Dataset |
-1.2 | | Lox | '10 nanogram per milliliter; TGF-beta1' vs 'none' in 'multipotent progenitor' at '8 hour' | cell type, compound, time | Dynamic Gene Expression Response to TGF-b Stimulation in Multipotent Progenitors and Common Dendritic Cell Progenitors |
-1.2 | | Lox | 'old neuronal stem cells' vs 'young neuronal stem cells' | age | A mechanism for the segregation of age in mammalian neural stem cells |
-1.2 | | Lox | 'side population cells' vs 'main population cells' in 'muscle' | cell type, organism part | Gene expression of side population and main population cells, isolated from adult murine skeletal muscle and bone marrow |
1.2 | | Lox | 'Dmd-mdx mutation' vs 'wild type genotype' in 'none' | compound, genotype | RNA-seq comparison of fibro-adipogenic progenitors (FAPs) from wild type, mdx and cardiotoxin-injured mice |
-1.2 | | Lox | 'stem cell of gastric corpus gland' vs 'epithelial cell of stomach' | cell type | Bulk RNA-seq of proliferating cells in the mouse stomach corpus epithelium from FUCCI mouse. |
-1.2 | | Lox | 'CD47 knockdown; endothelial’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
-1.2 | | Lox | 'DAPT' vs 'dimethyl sulfoxide' in 'Ngn3tTA/tTA' | compound, genotype | Neurog3-independant role of Notch signaling in pancreas explants. Microarray of pancreata of Wildtype or Neurog3tTA/tTA (Neurog3-Null) background at E12.5, explanted for 3d + treatment 24h with DAPT/vehicle. |
-1.2 | | Lox | 'Zfp521 knockdown by siRNA' vs 'wild type' at '1 day' | phenotype, time | 3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1 |
1.2 | | Lox | 'tumor' vs 'normal' in 'liver' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
1.1 | | Lox | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.1 | | Lox | '3 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
1.1 | | Lox | 'mdx/mdx' vs 'wild type' | genotype | Transcription profiling by array of mdx mouse gastrocnemius muscle |
1.1 | | Lox | 'seizure-preconditioning followed by intra-amygdala kainic acid' vs 'sham-preconditioning followed by intra-amygdala vehicle' | clinical treatment | Transcription profiling by array of mice with epileptic tolerance |
1.1 | | Lox | 'FVBNCr; RML infected' at '22 week' vs 'FVBNCr; uninfected' at '22 week' | strain, time, treatment | Transcription profiling of mouse brain infected with prions in eight mouse-prion strain combinations in a systems approach to the study of prion disease |
1.1 | | Lox | 'phosgene - carbonyl chloride' at '12 hour' vs 'air' at '12 hour' | compound, time | Transcription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanism of phosgene-induced lung injury |
-1.1 | | Lox | '500 micromolar palmitate' vs '1 volume percent bovine serum albumin' | compound | Transcription profiling of mouse C2C12 myotubes treated overnight with 500 uM palmitate or 1% bovine serum albumin control to identify mediators of obesity-linked reductions in PGC-1 |
-1.1 | | Lox | 'trypsinized and mock FACS sorted' vs 'untreated' | treatment | Expression data from mammary epithelial cells harvested from 8-9 week old C3H female mice - various isolation conditions |
1.1 | | Lox | 'hyperoxia' vs 'control' in 'female' | sex, stimulus | Transcription profiling by array of lung tissues from wild-type male and female C56BL/6J mice either maintained in room air or exposed to hyperoxia (FiO2>95%) for 48 hours |
-1.1 | | Lox | 'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
1.1 | | Lox | 'IL-6' at '2 hour' vs 'none' at '0 hour' | compound, time | Time-series of IL-6 stimulated primary mouse hepatocytes |
-1.1 | | Lox | 'shRNA mediated Brd4 knockdown' vs 'control shRNA' | treatment | Expression Data For BRD4 Inhibition |
1.1 | | Lox | 'hepatic stellate cell' vs 'quiescent hepatic stellate cells' | cell type | Deactivation of Hepatic Stellate Cells during Liver Fibrosis Resolution in Mice |
1.1 | | Lox | Synacthen vs sodium chloride control | compound | Transcription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses. |
1.1 | | Lox | 'transgenic' vs 'wild type' in '152 day; C57BL/6' | age, genotype, strain | Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models |
1.1 | | Lox | 'dysferlin mutant' vs 'wild type' in 'skeletal muscle' | genotype, organism part | Transcription profiling by array of skeletal and cardiac muscle from dysferlin-deficient mice |
-1.1 | | Lox | 'Fam208a homozygous mutant' vs 'wild type' | block, genotype | The epigenetic modifier Fam208a is required to maintain epiblast cell potency |
-1.1 | | Lox | 'cetrorelix; 3 milligram per kilogram' vs 'none' in 'inh-alpha/Tag transgenic' | compound, genotype | Novel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice. |
-1.1 | | Lox | 'Macrophage of F4/80+, CD11b+, CD11c-; obese leptin-deficient' vs 'Macrophage of F4/80+, CD11b+, CD11c-; control' | cell type, genotype | Expression data from mouse adipose tissue macrophage |
-1.1 | | Lox | 'stabilization-competent' vs 'stabilization-incompetent' in '22 day; secondary reprogramming cell' | age, cell type, phenotype | Transcription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture |
1.1 | | Lox | 'TAC surgery' vs 'sham surgery' in 'C57BL/6J' | strain, treatment | Transcription profiling of left ventricular myocardium after sham or TAC surgery in BL/6N and BL/6J mice |
1.1 | | Lox | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1 | | Lox | 'recombinant Fgf10 (1 milligram per milliliter)' vs 'PBS' in 'wild type genotype' | genotype, stimulus | Role of Fgf10 signalling in regulation of gene expression in developing mouse cortex |
1 | | Lox | 'sclerostin-inhibiting antibody' vs 'PBS' | stimulus | RNA-seq of diaphyseal bone from sclerostin-neutralizing antibody treated mice |
1 | | Lox | 'corpus striatum' at 'rheumatoid arthritis model expressing hsTNFɑ' vs 'wild type' | disease, organism part, phenotype | Regional CNS immune fingerprint in chronic peripheral inflammation |
-1 | | Lox | 'brown adipose tissue' vs 'white adipose tissue' in 'high fat diet; 30 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1 | | Lox | 'SR-BI-/- apoE-/-' vs 'control' in '31 day; Chow diet' | age, diet, genotype | Expression data from the hearts of a mouse model of spontaneous myocardial infarction |
1 | | Lox | '12 day' vs '3 day' | time | Transcription profiling time series of mouse embryonic chondrocyte differentiation |
1 | | Lox | 'sham-preconditioning followed by intra-amygdala kainic acid' vs 'sham-preconditioning followed by intra-amygdala vehicle' | clinical treatment | Transcription profiling by array of mice with epileptic tolerance |
-1 | | Lox | 'primary hair placode keratinocyte' vs 'interfollicular epidermal keratinocyte' | cell type | Transcription profiling of mouse primary hair placode keratinocytes compared to interfollicular epidermal keratinocytes |
1 | | Lox | 'ATF3 -/-' vs 'wild type' in '10 nanogram per milliliter; lipopolysaccharide' at '2 hour' | compound, genotype, time | Transcription profiling by array of mouse bone marrow macrophages mutant for ATF3 after treatment with lipopolysaccharide |
1 | | Lox | '15 day' vs '3 day' | time | Transcription profiling time series of mouse embryonic chondrocyte differentiation |
-1 | | Lox | 'tape stripping and oral administration of winged bean extract' vs 'tape stripping' | treatment | Transcription profiling by array of mouse dorsal skin after tape stripping and treatment with winged bean extract. |
1 | | Lox | 'chronic DSS-induced colitis; 2x DSS, additional recovery' vs 'none; none' | clinical treatment, disease | Transcription profiling by array of colon tissues isolated from mice with acute and chronic dextran sodium sulphate (DSS)-induced colitis |
1 | | Lox | 'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1 | | Lox | 'CD36 knockout' vs 'wild type genotype' in 'none' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
1 | | Lox | 'permanent neonatal diabetes mellitus' vs 'normal' | disease | Microarray comparing gene expression changes between control, normoglycaemic mice, and mice expressing the human neonatal diabetes mutation Kir6.2-V59M in pancreatic beta-cells left diabetic for 2 weeks |
1 | | Lox | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day' | genotype, infect, time | SM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice |
1 | | Lox | 'ColIITg cog' vs 'wild type genotype' in 'osteoarthritis, knee; right knee destabilisation of the medial meniscus' | disease, genotype, injury | RNA-seq of laser micro-dissected cartilage after surgical induction of osteoarthritis in increased ER stress mice |
-1 | | Lox | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '30 day' vs 'none' at '6 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1 | | Lox | 'trinitrobenzene sulfonic acid' vs 'none' in 'Fn14 knockout' | compound, genotype | Chronic TNBS Colitis in the FN14 KO Mouse |
1 | | Lox | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
1 | | Lox | 'transgenic' vs 'wild type' in '160 day; C57BL/6' | age, genotype, strain | Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models |
1 | | Lox | 'nutlin-3a; polarized with interleukin 4 and interleukin 13.' vs 'untreated' | compound, treatment | Expression data from polarized macrophages: effect of p53 |
-1 | | Lox | 'bevacizumab' vs 'control' | compound | Gene expression profile of U87-EV human glioblastoma xenograft tumours treated with bevacizumab or dibenzazepine |
1 | | Lox | 'trinitrobenzene sulfonic acid-induced experimental colitis' vs 'normal' in 'control' on 'Affymetrix MOE430A' | diet, disease | Transcription profiling by array of colon tissues from mice with or without trinitrobenzene-sulfonic acid induced colitis fed on standard diet or on anti-inflammatory compound Curcumin |
1 | | Lox | 'high fat' vs 'normal' in 'wild type' | diet, genotype | Gene expression from epidydimal fat pad |
1 | | Lox | 'Crx knockout' vs 'control' at '20 zeitgeber' | genotype, time | Transcriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20 |
-1 | | Lox | '2% curcumin' vs 'control' in 'trinitrobenzene sulfonic acid-induced experimental colitis' on 'Affymetrix MOE430A' | diet, disease | Transcription profiling by array of colon tissues from mice with or without trinitrobenzene-sulfonic acid induced colitis fed on standard diet or on anti-inflammatory compound Curcumin |
1 | | Lox | 'beta1-adrenoceptor overexpression' vs 'wild type' | genotype | Transcription profiling by array of CREM-knockout mice |
1 | | Lox | 'MYC inhibitor (10058F4); polarized with interleukin 4 and interleukin 13.' vs 'untreated' | compound, treatment | Expression data from polarized macrophages: effect of p53 |
-1 | | Lox | '10 nanogram per milliliter; TGF-beta1' vs 'none' in 'multipotent progenitor' at '12 hour' | cell type, compound, time | Dynamic Gene Expression Response to TGF-b Stimulation in Multipotent Progenitors and Common Dendritic Cell Progenitors |
1 | | Lox | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1 | | Lox | 'epithelium-specific Apc; Bcl9; Bcl9l knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1 | | Lox | 'Cnot3 knockout' vs 'wild type' | phenotype | RNA-seq of mouse islets from Ins1-cre driven Cnot3 KO and control islets |
1 | | Lox | 'utrophin/distrophin double knockout' vs 'distrophin knockout' in 'hindlimb muscle' | genotype, organism part | Transcription profiling of extraocular, hindlimb and cardiac muscles from dKO and MDX mice |