6.1 | | Knl1 | '21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
5.6 | | Knl1 | '21 percent oxygen, 37 degree Celsius, no serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
5.4 | | Knl1 | 'neural stem cell' vs 'niche cell' | cell type | Transcription profiling by high throughput sequencing of three populations of primary dentate gyrus cells |
-5 | | Knl1 | 'neuron' vs 'differentiating progenitor' | cell type | Transcription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line |
-4.4 | | Knl1 | 'postnatal >1 year; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
4.3 | | Knl1 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-4.3 | | Knl1 | '365 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-4.3 | | Knl1 | '180 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-4.2 | | Knl1 | '3D culture' vs '2D culture' | growth condition | mRNA-seq of mouse salivary gland cancer cells cultured in adherent or non-adherent culture |
-4 | | Knl1 | 'Helicobacter hepaticus' vs 'none' in 'wild type phenotype' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
-3.9 | | Knl1 | '60 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
3.9 | | Knl1 | 'tumor' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
-3.9 | | Knl1 | 'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-3.8 | | Knl1 | '730 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
3.8 | | Knl1 | 'transplanted secondary tumors' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
3.7 | | Knl1 | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
3.6 | | Knl1 | 'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-3.6 | | Knl1 | '90 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-3.5 | | Knl1 | '6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
-3.5 | | Knl1 | '6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
3.5 | | Knl1 | 'inh-alpha/Tag transgenic' vs 'wild type' in 'none' | compound, genotype | Novel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice. |
3.5 | | Knl1 | 'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
3.4 | | Knl1 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-3.4 | | Knl1 | '3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
-3.4 | | Knl1 | '21 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-3.3 | | Knl1 | 'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
-3.3 | | Knl1 | 'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
-3.3 | | Knl1 | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
3.3 | | Knl1 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-3.2 | | Knl1 | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-3.2 | | Knl1 | 'AZD5069; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
3.2 | | Knl1 | 'neural progenitor cell' vs 'niche cell' | cell type | Transcription profiling by high throughput sequencing of three populations of primary dentate gyrus cells |
-3.1 | | Knl1 | 'Debaryomyces hansenii' at '24 hour' vs 'none' at '0 hour' | stimulus, time | RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls |
-3.1 | | Knl1 | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
3.1 | | Knl1 | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
-3.1 | | Knl1 | '3 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
3.1 | | Knl1 | 'Rb^{lox/lox}; p130^{lox/lox}; p107+/-' vs 'wild type' | genotype | Transcription profiling by array of livers from the mouse model of human hepatocellular carcinoma |
3 | | Knl1 | 'Triple knockout (Zfp36-/-, TNFR1-/-, TNFR2-/-)' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens |
3 | | Knl1 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-3 | | Knl1 | '6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
2.9 | | Knl1 | 'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
2.9 | | Knl1 | 'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
-2.9 | | Knl1 | '3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
-2.9 | | Knl1 | 'lipopolysaccharide; 10 nanogram per milliliter and PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2.8 | | Knl1 | 'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
2.8 | | Knl1 | 'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week' | age, genotype | Prevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA |
-2.8 | | Knl1 | '2.5 milligram per milliliter; Fibrinogen' at '12 hour' vs 'none' | compound, time | Transcription profiling by array of adult mouse neural stem cell differentiation after 3 and 12 hours of fibrinogen treatment |
-2.8 | | Knl1 | 'renin-expression' vs 'control' | phenotype | Expression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein. |
2.8 | | Knl1 | 'glioblastoma multiforme' vs 'normal' | disease | Analysis of the expression profiles of glioma-associated microglia/macrophages and naive control cells in Mus musculus. |
2.8 | | Knl1 | 'erythroblast' vs 'hematopoietic stem cell' | cell type | Transcription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells |
2.7 | | Knl1 | 'cut nerve; 7 day' vs 'none' | injury, protocol, time | Changes in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury |
-2.7 | | Knl1 | '30 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
2.7 | | Knl1 | 'PTEN null, P53-/-' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
2.7 | | Knl1 | 'CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype' | genotype, treatment | Gene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice. |
2.7 | | Knl1 | 'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'neutrophil' | cell type, genotype | RNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice |
2.7 | | Knl1 | 'SARS coronavirus MA15' vs 'none' at '7 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
2.6 | | Knl1 | 'Irx3 knockout' vs 'control' at '7 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
-2.6 | | Knl1 | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
-2.6 | | Knl1 | '6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
2.6 | | Knl1 | 'heart-specific Mdm2 knockout; 14 day' vs 'heart-specific Mdm2 knockout; 7 day' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
-2.6 | | Knl1 | 'p19Arf and interferon beta' vs 'eGFP control' | genotype | Transcription profiling by microarray of mouse B16F10 cells transduced with cDNAs encoding eGFP control, p19Arf, murine interferon-beta (IF-B) or the combination of p19Arf plus IF-B to study the modulated genes |
2.6 | | Knl1 | 'cyclophosphamide-induced cystitis' vs 'normal' | disease | Transcriptional profiling of mouse urinary bladder with cyclophosphamide-induced cystitis |
-2.6 | | Knl1 | '15 day' vs '0 day' | age | Time course analysis of the cardiac transcriptome in the neonatal period |
-2.6 | | Knl1 | 'lipopolysaccharide; 10 nanogram per milliliter and SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2.6 | | Knl1 | 'doxycycline-induced inactivation of ErbB3' vs 'ErbB3 expression' | phenotype | Transcription profiling by array of mouse mammary epithelial organoids after doxycyline-induced repression of ErbB3 expression |
-2.5 | | Knl1 | 'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
2.5 | | Knl1 | 'wild type; SARS MA15; 7 day' vs 'wild type; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
-2.5 | | Knl1 | 'granulocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
2.5 | | Knl1 | 'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '7 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
2.5 | | Knl1 | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day' | genotype, infect, time | SM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice |
-2.5 | | Knl1 | 'cetrorelix; 3 milligram per kilogram' vs 'none' in 'inh-alpha/Tag transgenic' | compound, genotype | Novel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice. |
2.4 | | Knl1 | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'biliary-derived proliferative ducts (bilDP)' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
2.4 | | Knl1 | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day' | genotype, infect, time | SM020 - Infection with SARS MA15 of C57BL/6J mice and KEPI (ppp1r14c) knockouts |
2.4 | | Knl1 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
2.4 | | Knl1 | 'V6.5; embryonic stem cell’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
2.4 | | Knl1 | 'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '7 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
2.4 | | Knl1 | 'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '7 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
2.3 | | Knl1 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
2.2 | | Knl1 | 'stem cell of gastric corpus gland' vs 'epithelial cell of stomach' | cell type | Bulk RNA-seq of proliferating cells in the mouse stomach corpus epithelium from FUCCI mouse. |
-2.2 | | Knl1 | 'NrlGFP positive' vs 'NrlGFP negative' | phenotype | Transcription profiling by array of photoreceptor precursor cells selected via cell surface antigen expression. |
2.2 | | Knl1 | 'M-CSF' at '3 day' vs 'none' at '0 day' | compound, time | Microarray profiling of polyploid macrophage progeny |
-2.2 | | Knl1 | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
2.2 | | Knl1 | 'TIMP1 knockout; SARS MA15; 7 day' vs 'TIMP1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
2.2 | | Knl1 | 'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
2.2 | | Knl1 | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-2.2 | | Knl1 | 'heart-specific Mdm2 knockout; 7 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
-2.2 | | Knl1 | 'heart-specific p53 knockout; 7 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
-2.2 | | Knl1 | 'p19Arf' vs 'eGFP control' | genotype | Transcription profiling by microarray of mouse B16F10 cells transduced with cDNAs encoding eGFP control, p19Arf, murine interferon-beta (IF-B) or the combination of p19Arf plus IF-B to study the modulated genes |
2.2 | | Knl1 | 'NEMO knockout' vs 'wild type' | genotype | TNFR1 controls apoptosis and chronic liver disease in hepatocyte-specific IKKγ (Nemo) mice. |
-2.2 | | Knl1 | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar and interferon beta; 100 units per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.2 | | Knl1 | 'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'classical monocyte' | cell type, genotype | RNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice |
2.2 | | Knl1 | '130 week' vs '13 week' in 'spleen' | age, organism part | Transcription profiling by array of liver, lung, spleen and kidney from young and old mice. |
2.1 | | Knl1 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2.1 | | Knl1 | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
-2.1 | | Knl1 | 'anti-CD3/CSA' vs 'anti-CD3' in 'cyclosporine-sensitive' | phenotype, treatment | Activating CD8 T cell clones via the T cell receptor complex in the absence and presence of cyclosporine A |
2.1 | | Knl1 | 'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout' | compound, genotype, infect | 4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies |
2.1 | | Knl1 | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day' | genotype, infect, time | SM015 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1a/1b knockouts |
2.1 | | Knl1 | 'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell' | age, cell type, phenotype | Transcription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture |
2.1 | | Knl1 | 'heart-specific p53 and Mdm2 knockout; 7 day' vs 'heart-specific p53 and Mdm2 knockout; 1 day' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
-2.1 | | Knl1 | 'interferon beta' vs 'eGFP control' | genotype | Transcription profiling by microarray of mouse B16F10 cells transduced with cDNAs encoding eGFP control, p19Arf, murine interferon-beta (IF-B) or the combination of p19Arf plus IF-B to study the modulated genes |
2.1 | | Knl1 | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '7 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-2.1 | | Knl1 | 'lipopolysaccharide' vs 'none' in 'bone marrow; wild type' | cell type, compound, genotype | Transcription profiling by high throughput sequencing of spleens of GPR34 knockout and wild type mice |
2.1 | | Knl1 | 'NEMO-TNFR1 double knockout' vs 'wild type' | genotype | TNFR1 controls apoptosis and chronic liver disease in hepatocyte-specific IKKγ (Nemo) mice. |
2 | | Knl1 | 'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-2 | | Knl1 | 'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
2 | | Knl1 | 'RBM20 antisense oligonucleotide' vs 'none' in 'Titin-N2B knockout' | RNA interference, genotype | Heart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF) |
2 | | Knl1 | 'carcinoma' vs 'normal' | disease | Gene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse |
2 | | Knl1 | 'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '7 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
-2 | | Knl1 | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-2 | | Knl1 | 'CD47 knockdown; endothelial’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
2 | | Knl1 | 'bone marrow macrophage; co-cultured with breast cancer cell line 4T1.2' vs 'bone marrow macrophage; control' | cell type, growth condition | Transcription profiling of mouse bone marrow macrophages (BMM) compared to BMM co-cultured with 4T1.2 breast cancer cells, treated with tumour cell supernatant, or RAW macrophage cell line |
1.9 | | Knl1 | 'RBM20 antisense oligonucleotide' vs 'none' in 'wild type genotype' | RNA interference, genotype | Heart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF) |
1.9 | | Knl1 | 'wild type genotype; SARS MA15; 7 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-1.9 | | Knl1 | '14 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
1.9 | | Knl1 | 'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
1.9 | | Knl1 | 'SARS coronavirus MA15' vs 'none' in 'Tnfrsf1a/1b -/-' at '7 day' | genotype, infect, time | SM015 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1a/1b knockouts |
1.9 | | Knl1 | 'PAI1 knockout; SARS MA15; 7 day' vs 'PAI1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1.9 | | Knl1 | 'PLAT knockout; SARS MA15; 7 day' vs 'PLAT knockout; mock' | genotype, infect, time | SARS infection of C57BL6, and PLAT knock-out mice |
1.9 | | Knl1 | 'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre-' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
1.9 | | Knl1 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.9 | | Knl1 | 'SARS coronavirus MA15; 10^2 PFU' vs 'none' at '7 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1.9 | | Knl1 | 'lung carcinoma' vs 'normal' in 'Epcam+CD11b-CD11c- epithelial cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
-1.9 | | Knl1 | 'expanded on HUVEC and m5GF in the presence of mD1R for 7 days' vs 'control' | treatment | Expression data from cultured c-Kit+Sca-1+Lin- (KSL)cells |
1.8 | | Knl1 | 'Yersinia pestis' vs 'control' in 'neutrophil' | cell type, infect, sampling site | Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague |
-1.8 | | Knl1 | 'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
1.8 | | Knl1 | 'extracellular vesicle; MET cell culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-1.8 | | Knl1 | 'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-1.8 | | Knl1 | 'Drosha -/-' vs 'wild type genotype' | genotype | RNA-seq of mouse ES cells with conditional Drosha knockout against wild type controls to identify pri-miRNAs |
-1.8 | | Knl1 | 'TLR4 mutant' vs 'wild type genotype' in 'CCl4 and diethylnitrosamine' | genotype, treatment | Gene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice. |
1.8 | | Knl1 | 'SARS coronavirus MA15' vs 'none' in 'Tnfrsf1a/1b -/-' at '4 day' | genotype, infect, time | SM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice |
-1.8 | | Knl1 | 'heart-specific p53 and Mdm2 knockout; 1 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
1.8 | | Knl1 | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
1.8 | | Knl1 | 'Cbs knockout' vs 'wild type' | genotype | Gene expression profile of CD4-positive T cells from mouse Cbs knockout |
-1.7 | | Knl1 | 'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1' | cell type, growth condition, phenotype | Transcription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture |
-1.7 | | Knl1 | 'high GLUT1 expression' vs 'low GLUT1 expression' in 'wild type genotype' | genotype, phenotype | RNA-seq analysis of normoxic and hypoxic tumor-associated macrophages from wild type or REDD1 knockout mice |
1.7 | | Knl1 | 'Kit ligand' vs 'none' in 'wasp knockout' | compound, genotype | Transcription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand |
-1.7 | | Knl1 | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
1.7 | | Knl1 | 'nmf205, Gcn2 double mutant' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing in cerebellum of mouse Gcn2 -/-, nmf205-/- and nmf205-/-;Gcn2-/- |
1.7 | | Knl1 | 'M-CSF and FSL-1' at '3 day' vs 'none' at '0 day' | compound, time | Microarray profiling of polyploid macrophage progeny |
-1.7 | | Knl1 | 'CDK4/6 inhibitor PD 0332991' vs 'vehicle' | compound | Gene expression profile of mouse breast cancer V720 cells treated with vehicle or PD 0332991 |
-1.7 | | Knl1 | '10 Gy Gray; x-ray' vs 'none' in 'tumor and stromal cell' | cell type, irradiate | RNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated |
1.7 | | Knl1 | 'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs' | growth condition | RNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs |
1.7 | | Knl1 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
1.7 | | Knl1 | 'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '4 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
1.7 | | Knl1 | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
1.7 | | Knl1 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-1.6 | | Knl1 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '30 day' vs 'none' at '6 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.6 | | Knl1 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.6 | | Knl1 | 'Mkl1-RFP with a deletion of the SAP domain' vs 'full length Mkl1-RFP' | genotype | Transcription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1) |
-1.6 | | Knl1 | 'Nrl-/-' vs 'wild type' | genotype | Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Nrl-/- Retinal Transcriptomes |
-1.6 | | Knl1 | 'Tbx5;Nkx2-5 knockout' vs 'wild type' | genotype | Transcription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse |
-1.6 | | Knl1 | 'untreated; Csf2rb-/-' vs 'untreated; wild type' | clinical history, genotype | Mouse GM-CSF-related alveolar macrophage genome-wide expression data |
-1.6 | | Knl1 | 'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'wild type genotype' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
-1.6 | | Knl1 | 'CD47 knockdown; cell from embryoid body-like cluster’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
1.6 | | Knl1 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.6 | | Knl1 | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.6 | | Knl1 | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
1.6 | | Knl1 | 'hepatocyte-specific Pten knockout' vs 'wild type' | genotype | Hepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice |
1.5 | | Knl1 | 'LDB1 knock-down with Ldb1 delta 4/5 construct' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
1.5 | | Knl1 | 'Kit ligand; wasp knockout' vs 'Kit ligand; wild type' | compound, genotype | Transcription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand |
1.5 | | Knl1 | 'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '4 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
-1.5 | | Knl1 | 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 0 day' | cell type, compound, time | Drug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs |
-1.5 | | Knl1 | 'osteoblast culture 9 day' vs '0 day' | time | Transcription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation |
-1.5 | | Knl1 | 'osteoblast culture 27 day' vs '0 day' | time | Transcription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation |
1.5 | | Knl1 | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
1.5 | | Knl1 | '24 hour before induction of differentiation' vs 'induction of differentiation' | compound, sampling time point | Expression Profiling of Early Myogenesis - Affymetrix Dataset |
-1.5 | | Knl1 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1.5 | | Knl1 | 'Pkhd1Cre; Pkd2 F/F; miR-21null' vs 'wild type' | genotype | Next Generation Sequencing of PKD2 mutant mice kidneys |
1.5 | | Knl1 | 'acute graft vs. host disease' vs 'normal' | compound, disease | Transcription profiling by array of murine thymus medulla in the absence and presence of acute graft-versus-host disease |
-1.5 | | Knl1 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1.4 | | Knl1 | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
1.4 | | Knl1 | 'Trichuris muris' vs 'control' in 'mesenteric lymph node' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
1.4 | | Knl1 | 'Mycobacterium tuberculosis H37Rv' vs 'none' in 'wild type' | compound, genotype, infect | 4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies |
-1.4 | | Knl1 | '3 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
-1.4 | | Knl1 | '10 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-1.4 | | Knl1 | 'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2' | genotype, irradiate | RNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy |
1.4 | | Knl1 | 'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
1.4 | | Knl1 | 'Duchenne muscular dystrophy' vs 'normal' | disease | RNA-seq comparison of immortalised myoblasts from dystrophic and WT mice |
1.4 | | Knl1 | 'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, and PLAT knock-out mice |
1.4 | | Knl1 | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.4 | | Knl1 | 'Ngn3-expressing cell' vs 'Ngn3-null cell' | cell type | Transcriptional profiling of Ngn3-dependent pancreatic endocrine differentiation at E15.5 |
1.4 | | Knl1 | 'one year after pulmonary macrophage transplantation; Csf2rb-/-' vs 'untreated; Csf2rb-/-' | clinical history, genotype | Mouse GM-CSF-related alveolar macrophage genome-wide expression data |
-1.4 | | Knl1 | 'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in' | genotype, growth condition | Transcription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock |
-1.4 | | Knl1 | 'heart-specific p53 knockout; 28 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
1.4 | | Knl1 | 'antibiotics, CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype' | genotype, treatment | Gene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice. |
1.4 | | Knl1 | '3 day' vs '0 day' | age | Time course analysis of the cardiac transcriptome in the neonatal period |
-1.4 | | Knl1 | 'curdlan' vs 'none' in 'wild type' | compound, genotype | Dendritic cell-derived IL-2 promotes apoptosis of terminally mature cells via a novel autocrine signaling pathway |
1.4 | | Knl1 | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-1.3 | | Knl1 | 'Debaryomyces hansenii' at '12 hour' vs 'none' at '0 hour' | stimulus, time | RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls |
1.3 | | Knl1 | 'developmentally competent embryo conditioned media' vs 'control' | treatment | Developmentally Abnormal Human Embryos Trigger a Maternal ER Stress Response |
-1.3 | | Knl1 | 'LDB1 knock-down with full-length Ldb1 construct' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
1.3 | | Knl1 | 'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '4 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
1.3 | | Knl1 | 'dinitrofluorobenzene' vs 'control' in 'wild type' | compound, genotype | Transcription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity |
-1.3 | | Knl1 | 'miR-155 knockout' vs 'wild type' in 'natural killer cell' | cell type, genotype | Context- and cell-type specific function of miR155-Socs1 interaction in immune regulation |
1.3 | | Knl1 | 'liver-specific Cnot1 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
-1.3 | | Knl1 | 'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'wild type' | genotype, growth condition | Transcription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock |
1.3 | | Knl1 | 'Cbfb+/MYH11' vs 'control of Cbfb+/MYH11' | genotype | Transcription profiling by array of Mus musculus expressing Cbfb-MYH11 |
1.3 | | Knl1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.3 | | Knl1 | 'Nix knock out' vs 'wild type' | genotype | Transcription profiling by array of spleens from mice with Nix knocked out. |
1.3 | | Knl1 | 'tumor' vs 'normal' in 'liver' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
-1.3 | | Knl1 | 'polarized with E coli lipopolysacharide and INF-gamma' vs 'untreated' | compound, treatment | Expression data from polarized macrophages: effect of p53 |
-1.3 | | Knl1 | 'IL2 knockout' vs 'wild type' | compound, genotype | Dendritic cell-derived IL-2 promotes apoptosis of terminally mature cells via a novel autocrine signaling pathway |
1.3 | | Knl1 | 'Pkhd1Cre; Pkd2 F/F' vs 'wild type' | genotype | Next Generation Sequencing of PKD2 mutant mice kidneys |
-1.3 | | Knl1 | 'nutlin-3a; polarized with interleukin 4 and interleukin 13.' vs 'untreated' | compound, treatment | Expression data from polarized macrophages: effect of p53 |
1.2 | | Knl1 | 'Plasmodium berghei' vs 'none' in 'none' | compound, infect | Transcription profiling by array of mouse blood infected with Plasmodium berghei after treatment with activated charcoal |
1.2 | | Knl1 | 'epithelium-specific Apc; Bcl9; Bcl9l knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1.2 | | Knl1 | '3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
-1.2 | | Knl1 | 'NOD' vs 'C57BL/6' in 'steady state' at '0 hour' | strain, time, treatment | Expression data from NOD and C57BL/6 mouse pancreas CD8α- Dendritic Cells (DCs) under steady-state and after in-vitro LPS stimulation |
-1.2 | | Knl1 | 'interleukin-3 and interleukin-33' vs 'interleukin-3' | growth condition | Stem cell factor programs the mast cell activation phenotype |
1.2 | | Knl1 | 'SARS coronavirus MA15 dORF6' vs 'none' at '4 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
1.2 | | Knl1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.2 | | Knl1 | 'Lkb1 -/- Pten-/-' vs 'wild type' | genotype | Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells |
1.2 | | Knl1 | 'SARS coronavirus MA15; 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.2 | | Knl1 | 'tamoxifen; autosomal dominant polycystic kidney disease' vs 'none; normal' | compound, disease, time | Expression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC |
-1.2 | | Knl1 | 'co-culture' vs 'separate' in 'wild type genotype' | genotype, growth condition | RNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions |
-1.2 | | Knl1 | '17-beta estradiol; 0.05 milligram; continuous release pellets over 60 days' vs 'none' in 'FvB' | compound, genotype, treatment | GENE EXPRESSION PROFILE REGULATED BY THE HPV16-E7 ONCOPROTEIN AND ESTRADIOL IN CERVICAL TISSUE |
-1.2 | | Knl1 | 'Socs1 knock-in' vs 'wild type' in 'natural killer cell' | cell type, genotype | Context- and cell-type specific function of miR155-Socs1 interaction in immune regulation |
1.2 | | Knl1 | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.2 | | Knl1 | 'extracellular vesicle; EMT cell culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
1.2 | | Knl1 | '2 Gray; total body irradiation' vs 'none' in 'none' | irradiate, stimulus | RNA-seq on hematopoietic stem cells sorted from mice 1 month after they were irradiated (2Gy total body irradiation = IR) or not (non irradiated = NIR) and with or without prior TNFa treatment (IR_TNF) |
1.2 | | Knl1 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.2 | | Knl1 | 'AhCre Apc Floxed' vs 'control' | genotype | Cited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis |
-1.1 | | Knl1 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; MEF2C/D knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.1 | | Knl1 | 'high GLUT1 expression' vs 'low GLUT1 expression' in 'Ddit4 knockout' | genotype, phenotype | RNA-seq analysis of normoxic and hypoxic tumor-associated macrophages from wild type or REDD1 knockout mice |
1.1 | | Knl1 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.1 | | Knl1 | 'Plasmodium berghei ANKA' at '6 day' vs 'none' at '0 day' in 'none' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.1 | | Knl1 | 'lacZ positive (Wnt+)' vs 'control' | genotype | Gene expression analysis of Wnt+ and Wnt- effector CD8 T cells |
1.1 | | Knl1 | 'chronic cystitis' vs 'none' in 'C57/Bl6' | disease, strain | Chronic cystitis microarray comparing C3H/HeN and C57BL/6 bladder gene expression |
1.1 | | Knl1 | 'Plasmodium chabaudi infection' vs 'no infection' in 'adjuvant only' | infect, treatment | Protective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase |
1.1 | | Knl1 | 'lymphocytic choriomeningitis virus WE' vs 'normal' | disease | Transcription profiling by array of lymphocytic choriomeningitis virus-strain WE (LCMV-WE) infected mice versus naive mice. |
1.1 | | Knl1 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.1 | | Knl1 | 'alpha-amanitin; maternal Ring1-Rnf+' vs 'none; maternal Ring1-Rnf+' | compound, genotype | Polycomb function during oogenesis is required for mouse early embryonic development (2-cell embryos) |
1.1 | | Knl1 | 'Roquinsan/san(sanroque)' vs 'wild type' | genotype | Expression data from CD44loCD8+ T cells of sanroque versus wild-type mice |
1.1 | | Knl1 | 'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1.1 | | Knl1 | 'expression of Pax5' vs 'control (empty vector)' | genotype | Germline Aberrations of PAX5 Cause Susceptibility to pre-B cell Acute Lymphoblastic Leukemia |
1.1 | | Knl1 | 'TIMP1 knockout; SARS MA15; 4 day' vs 'TIMP1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1.1 | | Knl1 | 'stabilization-competent' vs 'stabilization-incompetent' in '22 day; secondary reprogramming cell' | age, cell type, phenotype | Transcription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture |
1.1 | | Knl1 | 'epithelium-specific Apc knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1.1 | | Knl1 | 'extracellular vesicle; non-stimulated culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
1.1 | | Knl1 | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '4 day' | genotype, infect, time | SM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice |
1.1 | | Knl1 | 'transgenic C3(1)-SV40Tag; 12 week' vs 'wild type; 8 week' | age, genotype | Prevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA |
1.1 | | Knl1 | 'Runx3 knockout' vs 'wild type genotype' | genotype | Runx3 function in splenic NK cells |
1.1 | | Knl1 | 'transgenic hepatic growth hormone and hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '12 week' | age, genotype | Hepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice |
-1.1 | | Knl1 | '50 micromolar; hydrogen peroxide' vs 'none' | compound | Transcription profiling by array of mouse dermal fibroblasts after treatment with hydrogen peroxide |
1.1 | | Knl1 | 'SOD1-G93A transgenic' vs 'wild type' at 'day 130/end-stage' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
-1.1 | | Knl1 | 'Stat5abfl/fl;MMTV-Cre' vs 'wild type' at 'pregnancy' | genotype, sampling time point | Transcription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy |
-1.1 | | Knl1 | 'K-ras mutant/Wt1-null' vs 'wild type' | genotype | Transcription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts |
1.1 | | Knl1 | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-1 | | Knl1 | 'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte' | cell type, compound, genotype | Transcription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin |
-1 | | Knl1 | '4-hydroxytamoxifen-mediated deletion of Prmt5' vs 'wild type' in 'mouse neural progenitor cell' | cell type, phenotype | Transcription profiling by high throughput sequencing of murine neural stem/progenitor cells lacking PRMT5 over control |
-1 | | Knl1 | 'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
1 | | Knl1 | 'Kit ligand' vs 'none' in 'wild type' | compound, genotype | Transcription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand |
-1 | | Knl1 | '10 Gy Gray; x-ray' vs 'none' in 'hematopoietic cell' | cell type, irradiate | RNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated |
-1 | | Knl1 | 'doxycycline; 200 nanogram per milliliter; neoplasm; 12 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
1 | | Knl1 | 'Dicer knock out' vs 'wild type' | genotype | Transcription profiling by array of mouse Dicer-deficient ooctyes |
1 | | Knl1 | 'M-CSF and FSL-1' at '6 day' vs 'none' at '0 day' | compound, time | Microarray profiling of polyploid macrophage progeny |
-1 | | Knl1 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '60 day' vs 'none' at '6 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1 | | Knl1 | 'diphtheria toxin; 30 nanogram per gram' vs 'none' | stimulus | RNA-seq of mouse brain tissue repopulating microglia in response to traumatic brain injury |
1 | | Knl1 | 'induced neural stem cell' vs 'mouse embryonic fibroblast cell' | cell type | Gene expression profile of mouse induced neural stem cells |
-1 | | Knl1 | 'interleukin-3 and stem cell factor' vs 'interleukin-3' | growth condition | Stem cell factor programs the mast cell activation phenotype |
-1 | | Knl1 | 'dox-induced over-expression of oncogenes for 5 days then off 7 days' vs 'untreated control' | phenotype | Temporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice |
1 | | Knl1 | 'Plasmodium chabaudi infection' vs 'no infection' in 'vaccination' | infect, treatment | Protective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase |
1 | | Knl1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1 | | Knl1 | 'curdlan' vs 'none' in 'IL2 knockout' | compound, genotype | Dendritic cell-derived IL-2 promotes apoptosis of terminally mature cells via a novel autocrine signaling pathway |
1 | | Knl1 | 'pulmonary hypertension' vs 'normal' | disease | Gene expression profile of lung with experimental Schistosoma-induced pulmonary hypertension in mouse |
1 | | Knl1 | '5 day' vs '0 day' | age | Time course analysis of the cardiac transcriptome in the neonatal period |
-1 | | Knl1 | 'subarachnoid hemorrhage' vs 'normal' | disease | Transcription profiling by array of the effect of SAH on brain cells in white matter region of mice |
1 | | Knl1 | 'Rb1 mutant' vs 'wild type' | genotype | A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene targeted mice |
1 | | Knl1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1 | | Knl1 | 'Sik1 knockout; gonad adipose tissue' vs 'wild type genotype; gonad adipose tissue' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |