ENSMUSG00000028825 (Rhd)

mus musculus

Rh blood group, D antigen

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Mus musculus
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Showing 2 experiments:
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
2.5364 × 10-55.9
Rhd'Plasmodium chabaudi infection' vs 'no infection' in 'vaccination'infect, treatmentProtective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase
Adjusted p-valueLog2-fold change
4.7674 × 10-55.8
Rhd'Plasmodium chabaudi infection' vs 'no infection' in 'adjuvant only'infect, treatmentProtective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase
Adjusted p-valueLog2-fold change
4.8054 × 10-11-5.6
Rhd'90 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
5.5191 × 10-11-5.6
Rhd'365 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
2.4512 × 10-65.6
Rhd'erythroblast' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
2.6695 × 10-10-5.5
Rhd'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
9.4379 × 10-95.5
Rhd'21 percent oxygen, 37 degree Celsius, no serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
3.9125 × 10-11-5.4
Rhd'180 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
3.2832 × 10-10-5.4
Rhd'21 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
6.0112 × 10-10-5.4
Rhd'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.8187 × 10-9-5.4
Rhd'30 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
3.4835 × 10-10-5
Rhd'14 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.0825 × 10-144.7
Rhd'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
3.0545 × 10-34.6
Rhd'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
4.3543 × 10-164.5
Rhd'Triple knockout (Zfp36-/-, TNFR1-/-, TNFR2-/-)' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens
Adjusted p-valueLog2-fold change
4.7675 × 10-14-4.3
Rhd'5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a'genotype, timeRNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating
Adjusted p-valueLog2-fold change
1.2772 × 10-74.2
Rhd'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
2.6806 × 10-34
Rhd'Cbs knockout' vs 'wild type'genotypeGene expression profile of CD4-positive T cells from mouse Cbs knockout
Adjusted p-valueLog2-fold change
1.4646 × 10-73.7
Rhd'14 days P. chabaudi infected' vs 'uninfected' in 'intact male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
4.0772 × 10-33.7
Rhd'21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
1.1426 × 10-3-3.4
Rhd'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
4.4808 × 10-23.4
Rhd'130 week' vs '13 week' in 'spleen'age, organism partTranscription profiling by array of liver, lung, spleen and kidney from young and old mice.
Adjusted p-valueLog2-fold change
1.5906 × 10-113.3
Rhd'14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
1.3351 × 10-103.2
Rhd'14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
1.9691 × 10-53.2
Rhd'14 days P. chabaudi infected' vs 'uninfected' in 'intact female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
8.0119 × 10-43.2
Rhd'extracellular vesicle; non-stimulated culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
8.8269 × 10-5-3.1
Rhd'renin-expression' vs 'control'phenotypeExpression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein.
Adjusted p-valueLog2-fold change
2.4034 × 10-4-3.1
Rhd'metaphase II oocyte' vs 'germinal vesicle oocyte'cell typeTranscription profiling of mouse in vivo matured MII oocytes and fully in vivo grown germinal vesicle oocytes to identify gene transcripts linked to epigenetic reprogramming
Adjusted p-valueLog2-fold change
2.0366 × 10-3-3.1
Rhd'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs'growth conditionRNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs
Adjusted p-valueLog2-fold change
2.2518 × 10-3-3.1
Rhd'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.6974 × 10-6-3
Rhd'doxycicline-mediated expression of c-Jun' vs 'control'phenotypeTranscription profiling by array of mouse whole bone marrow after c-Jun induction
Adjusted p-valueLog2-fold change
9.4257 × 10-53
Rhd'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
6.9751 × 10-3-3
Rhd'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.342 × 10-42.9
Rhd'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre-'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
4.5795 × 10-32.9
Rhd'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
9.8636 × 10-42.8
Rhd'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.3433 × 10-3-2.8
Rhd'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
3.7265 × 10-3-2.8
Rhd'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.6746 × 10-3-2.7
Rhd'germanium(2+)' vs 'normal chow'dietTranscription profiling by array of mouse treated with normal chow or that containing 0.15% germanium dioxide for four months
Adjusted p-valueLog2-fold change
1.1416 × 10-4-2.6
Rhd'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype'genotype, strainRNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice.
Adjusted p-valueLog2-fold change
2.4492 × 10-13-2.5
Rhd'beta cell specific Pax6 knockout' vs 'wild type'phenotypeRNA-Seq of pancreatic islets from beta cell-specific Pax6 knockout mice
Adjusted p-valueLog2-fold change
1.7921 × 10-32.5
Rhd'inducible deletion of Mll' vs 'control'treatmentMLL regulated genes in LSK/CD48- hematopoietic stem cells
Adjusted p-valueLog2-fold change
1.0809 × 10-2-2.5
Rhd'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
5.8249 × 10-52.3
Rhd'proliferating progenitor' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
1.6159 × 10-25-2.2
Rhd'Klf1-/-' vs 'wild type'genotypeNovel roles for Klf1 in regulating the erythroid transcriptome revealed by mRNA-seq
Adjusted p-valueLog2-fold change
5.3307 × 10-72.2
Rhd'Runx1 knockdown; none' vs 'wild type; none'genotype, stimulusTranscription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor
Adjusted p-valueLog2-fold change
1.4184 × 10-22.2
Rhd'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
3.1651 × 10-22.1
Rhd'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.6217 × 10-42
Rhd'Ela-Tgfa' vs 'wild type'genotypeTranscription profiling by array of pancreas from KrasG12D, Ela-Tgfa and KrasG12D Ela-Tgfa mice
Adjusted p-valueLog2-fold change
2.2995 × 10-4-2
Rhd'lymphocytic choriomeningitis virus WE' vs 'normal'diseaseTranscription profiling by array of lymphocytic choriomeningitis virus-strain WE (LCMV-WE) infected mice versus naive mice.
Adjusted p-valueLog2-fold change
2.5265 × 10-2-2
Rhd'7 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
2.6825 × 10-2-2
Rhd'MEF2C/D knockout' vs 'wild type genotype' in 'primary cell line; lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
4.866 × 10-41.9
Rhd'hypobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to hypobaric hypoxia at Mt. Everest in vivo.
Adjusted p-valueLog2-fold change
6.6517 × 10-51.8
Rhd'normobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
Adjusted p-valueLog2-fold change
2.5399 × 10-31.8
Rhd'Nix knock out' vs 'wild type'genotypeTranscription profiling by array of spleens from mice with Nix knocked out.
Adjusted p-valueLog2-fold change
3.4562 × 10-21.8
Rhd'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
5.3572 × 10-291.7
Rhd'Runx1 P1-GFP::P2-hCD4/-' vs 'wild type'genotypeRUNX1B expression distinguishes megakaryocytic and erythroid lineage fate in adult hematopoiesis
Adjusted p-valueLog2-fold change
1.5066 × 10-41.7
Rhd'RAW264.7 macrophage cell line; control' vs 'bone marrow macrophage; control'cell type, growth conditionTranscription profiling of mouse bone marrow macrophages (BMM) compared to BMM co-cultured with 4T1.2 breast cancer cells, treated with tumour cell supernatant, or RAW macrophage cell line
Adjusted p-valueLog2-fold change
4.3213 × 10-41.7
Rhd'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
3.0996 × 10-31.7
Rhd'3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
3.5888 × 10-141.6
Rhd'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
7.8096 × 10-5-1.6
Rhd'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
1.7079 × 10-4-1.6
Rhd'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
7.1149 × 10-31.6
Rhd'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
3.2446 × 10-2-1.6
Rhd'hematopoietic stem cell and hematopoietic multipotent progenitor cell' vs 'common myeloid progenitor'cell typeTranscription profiling by high throughput sequencing between multipotent hematopoietic stem progenitor cells LS+K) and myeloid committed cells (LS−K) of the mouse bone marrow
Adjusted p-valueLog2-fold change
8.0263 × 10-9-1.5
Rhd'Runx1 P1-GFP::P2-hCD4/+' vs 'wild type'genotypeRUNX1B expression distinguishes megakaryocytic and erythroid lineage fate in adult hematopoiesis
Adjusted p-valueLog2-fold change
2.0132 × 10-8-1.5
Rhd'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
1.2817 × 10-3-1.5
Rhd'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2-GFP knockin; Egr2-GFP high'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
2.5835 × 10-21.5
Rhd'stabilization-competent' vs 'stabilization-incompetent' in '22 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
3.514 × 10-21.5
Rhd'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
4.2645 × 10-21.5
Rhd'Ink4a/Arf-/-; EGFRvIII' vs 'wild type genotype' in 'separate'genotype, growth conditionRNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions
Adjusted p-valueLog2-fold change
1.9251 × 10-11-1.4
Rhd'α-GalCer; 2 microgram' vs 'none' in 'wild type genotype'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
7.3751 × 10-71.4
Rhd'16 day' vs '0 day'ageGene expression profile of mouse differentiating embryonic stem cells (day 0, 6, 16, and 26)
Adjusted p-valueLog2-fold change
2.7898 × 10-6-1.4
Rhd'Abcc8-/-' vs 'wild type genotype' in 'high fat; female'diet, genotype, sexEffects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
Adjusted p-valueLog2-fold change
1.3231 × 10-41.4
Rhd'V6.5; embryonic stem cell’ vs 'wild type; endothelial'cell line, cell type, genotypeCD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors
Adjusted p-valueLog2-fold change
2.1208 × 10-41.4
Rhd'induce erythroid differentiation' vs 'none' in 'wild type'genotype, stimulusTranscription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor
Adjusted p-valueLog2-fold change
2.4589 × 10-31.4
Rhd'mir181a1/b1 Knockout' vs 'wild type'genotypeMouse CD4+/CD8+ thymocytes from miR-181a1/b1 KO vs WT
Adjusted p-valueLog2-fold change
7.8006 × 10-171.3
Rhd'8.5 millimolar; methoxyacetic acid' vs 'none' at '24 hour'compound, timeTranscription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid
Adjusted p-valueLog2-fold change
9.2971 × 10-12-1.3
Rhd'Pcbp2 knockout' vs 'wild type genotype'genotypeTranscription profiling by RNA-seq of fetal liver from poly(C) binding protein 2 (Pcbp2) knockout mice
Adjusted p-valueLog2-fold change
9.0735 × 10-8-1.3
Rhd'Plasmodium berghei' vs 'none' in 'none'compound, infectTranscription profiling by array of mouse blood infected with Plasmodium berghei after treatment with activated charcoal
Adjusted p-valueLog2-fold change
2.2601 × 10-7-1.3
Rhd'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
1.3042 × 10-51.3
Rhd'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
9.7015 × 10-51.3
Rhd'7 days P. chabaudi infected' vs 'uninfected' in 'intact male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
1.2441 × 10-4-1.3
Rhd'Staphylococcus aureus Sanger476; 6 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.4818 × 10-2-1.3
Rhd'megakaryocyte' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
4.8655 × 10-2-1.3
Rhd'injected with sperm-derived RNA fragments from mice subjected to early life stress (MSUS)' vs 'injected with sperm-derived RNA fragments from control non-stressed mice'stimulusZygotic expression after parental early life stress
Adjusted p-valueLog2-fold change
5.6345 × 10-91.2
Rhd"98 to 119 week; reproductively old" vs "6 to 12 week; reproductively young"age, phenotypeRNAseq of whole ovarian follicles from young and old mice.
Adjusted p-valueLog2-fold change
5.765 × 10-9-1.2
Rhd'Sall4 -/-' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells in response to changes in Sall4
Adjusted p-valueLog2-fold change
1.9526 × 10-71.2
Rhd'Follicular B cell' vs 'Pre-B cell' in 'wild type genotype; MHC II-positive'cell type, genotype, phenotypeEffect of MHC II expression in pro-B cells: Pre-B cells and follicular B cells from wild-type and MHC II conditional mice
Adjusted p-valueLog2-fold change
1.6713 × 10-41.2
Rhd'estradiol' at '21 hour' vs 'none' at '0 hour'compound, timeTranscription profiling by array of G1E cells during time course treatment with estradiol.
Adjusted p-valueLog2-fold change
2.3955 × 10-41.2
Rhd'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
6.2049 × 10-3-1.2
Rhd'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
7.3407 × 10-31.2
Rhd'IkL/L mutant' vs 'wild type genotype'genotypeGene expression in WT and Ikaros-deficient LSK cells
Adjusted p-valueLog2-fold change
1.1595 × 10-161.1
Rhd'LKB1 knockout; floxed LKB1 with Ins1-Cre' vs 'floxed LKB1 without Ins1-Cre; wild type'genotype, phenotypeTranscription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice
Adjusted p-valueLog2-fold change
1.339 × 10-71.1
Rhd'LKB1 knockout; floxed LKB1 with RIP-Cre' vs 'floxed LKB1 without RIP-Cre; wild type'genotype, phenotypeTranscription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice
Adjusted p-valueLog2-fold change
3.1199 × 10-5-1.1
Rhd'RBM20 antisense oligonucleotide' vs 'none' in 'Titin-N2B knockout'RNA interference, genotypeHeart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF)
Adjusted p-valueLog2-fold change
4.3509 × 10-51.1
Rhd'heart-specific p53 knockout; 7 day' vs 'wild type phenotype'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
9.642 × 10-51.1
Rhd'estradiol' at '14 hour' vs 'none' at '0 hour'compound, timeTranscription profiling by array of G1E cells during time course treatment with estradiol.
Adjusted p-valueLog2-fold change
1.3285 × 10-4-1.1
Rhd'Abcc8-/-' vs 'wild type genotype' in 'high fat; male'diet, genotype, sexEffects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
Adjusted p-valueLog2-fold change
4.8311 × 10-4-1.1
Rhd'Runx3 knockout' vs 'wild type genotype'genotypeRunx3 function in CD8+ splenic T cells
Adjusted p-valueLog2-fold change
3.9668 × 10-2-1.1
Rhd'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha'genotype, stimulusRNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment
Adjusted p-valueLog2-fold change
1.6458 × 10-6-1
Rhd'Abcc8-/-' vs 'wild type genotype' in 'normal; male'diet, genotype, sexEffects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
Adjusted p-valueLog2-fold change
4.1387 × 10-61
Rhd'NHD13 mutant' vs 'wild type'genotypeMyelodysplastic syndrome: NUP98-HoxD13 (NHD13) expression effect on hematopoietic stem cells
Adjusted p-valueLog2-fold change
5.8716 × 10-6-1
Rhd'RBM20 antisense oligonucleotide' vs 'none' in 'wild type genotype'RNA interference, genotypeHeart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF)
Adjusted p-valueLog2-fold change
1.5466 × 10-5-1
Rhd'cardiac-specific constitutive expression of an activated Akt (caAkt)' vs 'wild type genotype'genotypeTranscription profiling by array of cardic ventricle tissues from mice with cardiac-specific constitutive expression of an activated Akt (caAkt) and wild-type controls to test whether Akt activation contributes to mitochondrial dysfunction in pathological cardiac hypertrophy
Adjusted p-valueLog2-fold change
6.5152 × 10-3-1
Rhd'Escherichia coli O18:K1:H7; 6 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
3.3043 × 10-2-1
Rhd'poly(I:C)' vs 'none'stimulus3’-Seq of ex vivo isolated mouse multipotent steady state hematopoietic stem cells (sHSC) and proliferating HSCs
Adjusted p-valueLog2-fold change
4.9666 × 10-21
Rhd'stabilization-competent' vs 'stabilization-incompetent' in '27 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Synonym
Rh, Rhced, Rhl1
Ortholog
ENSPANG00000010026 (Papio anubis), ENSOCUG00000001823 (Oryctolagus cuniculus), ENSCING00000008953 (Ciona intestinalis), ENSPPYG00000001710 (Pongo abelii), ENSCSAG00000000951 (Chlorocebus sabaeus), Rhd (Rattus norvegicus), ENSCSAVG00000007470 (Ciona savignyi), rhd (Tetraodon nigroviridis), RHD (Homo sapiens), ENSPTRG00000039847 (Tetraodon nigroviridis), ENSCSAVG00000009433 (Ciona savignyi), ENSOARG00020009279 (Salmo salar), ENSECAG00000013140 (Equus caballus), ENSCSAVG00000009731 (Ciona savignyi), ENSOANG00000038655 (Ciona intestinalis), rhd (Xenopus tropicalis), RHCE (Macaca mulatta), ENSDNOG00000017485 (Dasypus novemcinctus), rhr-2 (Caenorhabditis elegans), rhr-1 (Caenorhabditis elegans), ENSGGOG00000017174 (Gorilla gorilla), ENSACAG00000013694 (Anolis carolinensis), RHCE (Sus scrofa), ENSGGOG00000039842 (Gorilla gorilla), ENSBTAG00000001297 (Bos taurus), ENSMODG00000013982 (Monodelphis domestica), RHCE (Homo sapiens), ENSCING00000005428 (Ciona intestinalis), RHCE (Gallus gallus), ENSCING00000002595 (Salmo salar), ENSAPLG00000016375 (Anas platyrhynchos), rhd (Danio rerio), Rh50 (Drosophila melanogaster)
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
1417049_at, 4715780, 5119307, Msa.19100.0_s_at, 4849266, 10509002, 4835614, ILMN_2651609, 5141171, C77974_rc_g_at, 4681611, C77974_rc_at, 5205118, 4476760, 4838777, 5527172, 4453511, 17419799, 5493585, A_51_P241769, 4618426, 5533219, 103340_at