ENSMUSG00000032118 (Fez1)

mus musculus

fasciculation and elongation protein zeta 1 (zygin I)

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Mus musculus
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Showing 56 experiments:
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Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermhippocampuslungolfactory bulbskeletal muscle organtracheaaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartintestinal mucosalateral prominence neural epitheliummedial nasal prominencemuscle (biceps femoris)oviductpreoptic areaspleensubventricular zonevesicular glandwhole organism
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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14 - embryonic day 10.5
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 13
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Mammalian Kaessmann
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GENCODE
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Vertebrates
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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Developing gut
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49 FANTOM5 project - embryonic day 11
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3
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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3 Soumillon et al
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Sun et al., 2020 - Organism part
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4 Bonthuis et al - C57BL/6J
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Fat and muscle
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - lactating adult …
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Huttlin et al., 2010 - tissues - brain, …
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Linscheid et al., 2021 - tissue - heart …
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Duda et al., 2018 - organism part - …
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Linscheid et al. 2019 - organism part
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Deshmukh et al., 2015 - organism part
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Zhao et al., 2019 - tissue - lens
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Meierhofer et al., 2016 - organism part
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Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.1044 × 10-2-8.2
Fez1'CD81 positive' vs 'CD81 negative' in 'subcutaneous adipose tissue'organism part, phenotypeRNA-seq comparison of CD81 positive and negative cells in subcutaneous and visceral white fat and brown fat tissues in mouse
Adjusted p-valueLog2-fold change
1.4747 × 10-506.1
Fez1'5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a'genotype, timeRNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating
Adjusted p-valueLog2-fold change
4.6074 × 10-41-6.1
Fez1'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.8391 × 10-52-6
Fez1'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
7.9191 × 10-8-5.9
Fez1'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
5.6178 × 10-185.2
Fez1'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
7.5467 × 10-54.9
Fez1'19 to 22 month' vs '3 to 4 month' in 'endothelial cell'age, cell typeRNA-seq of 5 populations from the regenerative region of the brain of young and old mice
Adjusted p-valueLog2-fold change
2.0998 × 10-51-4.8
Fez1'interferon gamma' vs 'dexamethasone; 100 nanomolar'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
8.8494 × 10-134.7
Fez1'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
5.2249 × 10-744.2
Fez1'dexamethasone; 100 nanomolar; interferon gamma' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
8.9816 × 10-31-4.2
Fez1'Duchenne muscular dystrophy' vs 'normal'diseaseRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Adjusted p-valueLog2-fold change
4.1501 × 10-74.2
Fez1'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
1.0312 × 10-94.1
Fez1'6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
2.0868 × 10-83.9
Fez1'6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
4.1439 × 10-543.7
Fez1'dexamethasone; 100 nanomolar' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
4.5905 × 10-173.7
Fez1'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.3427 × 10-63.7
Fez1'144 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
1.2685 × 10-11-3.6
Fez1'ATF5 knockdown' vs 'wild type' in 'DMSO'compound, genotypeMicroarray to find ATF5 dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
7.9794 × 10-15-3.5
Fez1'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
5.2957 × 10-8-3.4
Fez1'lung carcinoma' vs 'normal' in 'lung cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
5.678 × 10-63.4
Fez1'Cbfb knockout' vs 'control of Cbfb knockout'genotypeTranscription profiling by array of Mus musculus expressing Cbfb-MYH11
Adjusted p-valueLog2-fold change
1.3977 × 10-23.4
Fez1'ICG-001 and PHA665752' vs 'DMSO'compoundTranscription profiling by array of mammospheres derived from tumors of mice harboring Wnt/Met signaling mutations treated Wnt and MET pathway inhibitors
Adjusted p-valueLog2-fold change
5.7765 × 10-93
Fez1'6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
6.3293 × 10-93
Fez1'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells'age, cell typeTranscriptional profiling of nascent and mature pancreatic beta cells
Adjusted p-valueLog2-fold change
9.7051 × 10-52.9
Fez1'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal'diseaseTranscription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma
Adjusted p-valueLog2-fold change
4.0051 × 10-142.8
Fez1'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
6.9142 × 10-3-2.8
Fez1'70 week' vs '6 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
3.4247 × 10-12-2.7
Fez1'hepatocyte-derived proliferative ducts (hepPDs)' vs 'biliary-derived proliferative ducts (bilDP)'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
8.0351 × 10-122.7
Fez1'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
3.721 × 10-72.7
Fez1'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte'cell type, compound, genotypeTranscription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin
Adjusted p-valueLog2-fold change
3.2214 × 10-42.7
Fez1'96 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
1.4965 × 10-202.6
Fez1'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
7.3087 × 10-182.6
Fez1'0.45 micromolar; 5-fluourouracil' vs 'none' at '24 hour'compound, timeTranscription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid
Adjusted p-valueLog2-fold change
1.1895 × 10-32.6
Fez1'transgenic humanSODG93A' vs 'wild type' in 'gastrocnemius'clinical treatment, genotype, organism partGene expression profiling of muscles from transgenic humanSODG93A mice at symptomatic stage
Adjusted p-valueLog2-fold change
1.8965 × 10-82.5
Fez1'3 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
1.2672 × 10-32.5
Fez1'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
6.8585 × 10-92.4
Fez1'Aire knockout' vs 'wild type' in 'cTEC'genotype, phenotypeTranscription profiling by high throughput sequencing of primary cTEC, mTEClo, and mTEChi harvested from wild type and Aire-deficient mice
Adjusted p-valueLog2-fold change
1.7996 × 10-72.4
Fez1'3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
4.6303 × 10-72.4
Fez1'6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
1.1547 × 10-32.4
Fez1'SOD1-G93A transgenic' vs 'wild type' at 'day 65' in 'B6/SJL'genotype, sampling time point, strainTranscription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
Adjusted p-valueLog2-fold change
2.2828 × 10-22.4
Fez1"muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP negative"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
3.3885 × 10-312.3
Fez1'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
3.1484 × 10-262.3
Fez1'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.111 × 10-62.3
Fez1'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
4.753 × 10-22.2
Fez1'transgenic humanSODG93A' vs 'wild type' in 'triceps'clinical treatment, genotype, organism partGene expression profiling of muscles from transgenic humanSODG93A mice at symptomatic stage
Adjusted p-valueLog2-fold change
9.8277 × 10-8-2.1
Fez1'Kit ligand; wasp knockout' vs 'Kit ligand; wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
2.4052 × 10-102
Fez1'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
5.3433 × 10-10-2
Fez1'MEF; transduced with MyoD lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
1.7038 × 10-8-2
Fez1'mutant MyoD expression' at '24 hour' vs 'wild type MyoD expression' at '0 hour'phenotype, timeTranscription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation.
Adjusted p-valueLog2-fold change
8.3176 × 10-72
Fez1'3 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
2.5548 × 10-9-1.9
Fez1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.2777 × 10-9-1.9
Fez1'MEF; transduced with NeuroD2 lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
3.406 × 10-71.9
Fez1'3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
6.9071 × 10-251.8
Fez1'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
1.6154 × 10-7-1.8
Fez1'NrlGFP positive' vs 'NrlGFP negative'phenotypeTranscription profiling by array of photoreceptor precursor cells selected via cell surface antigen expression.
Adjusted p-valueLog2-fold change
1.1057 × 10-6-1.8
Fez1'TLR9 ligand CpG ODN (1826)' vs 'none' in 'wild type genotype'genotype, stimulusTranscription profiling by sequencing of murine MyD88 -/- and MyD88 +/+ mTECs stimulated with a TLR9 ligand
Adjusted p-valueLog2-fold change
8.6375 × 10-41.8
Fez1'extracellular vesicle; MET cell culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
1.1263 × 10-3-1.8
Fez1'Insm1-expressing endocrine progenitor cell' vs 'Insm1-lacking endocrine progenitor cell' in 'embryonic day 15.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
3.993 × 10-3-1.8
Fez1'14M1.4; Leishmania donovani infected' at '48 hour' vs '14M1.4; normal' at '48 hour'cell line, infect, timeTranscription profiling of 3 mouse cell lines infected with Leishmania
Adjusted p-valueLog2-fold change
1.1807 × 10-21.8
Fez1'K-ras mutant/Wt1-null' vs 'wild type'genotypeTranscription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts
Adjusted p-valueLog2-fold change
1.7135 × 10-251.7
Fez1'Aire knockout' vs 'wild type' in 'mTEClo'genotype, phenotypeTranscription profiling by high throughput sequencing of primary cTEC, mTEClo, and mTEChi harvested from wild type and Aire-deficient mice
Adjusted p-valueLog2-fold change
2.9776 × 10-23-1.7
Fez1'cut nerve; 7 day' vs 'none'injury, protocol, timeChanges in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury
Adjusted p-valueLog2-fold change
7.4609 × 10-161.7
Fez1'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
6.2825 × 10-91.7
Fez1'mutant (Pdgfc-/-; Pdgfra GFP/+)' vs 'control'genotypeCerebral gene expression changes in Pdgfc and Pdgfra mutant
Adjusted p-valueLog2-fold change
1.9053 × 10-7-1.7
Fez1'5 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
3.8128 × 10-61.7
Fez1'interleukin-3 and stem cell factor' vs 'interleukin-3'growth conditionStem cell factor programs the mast cell activation phenotype
Adjusted p-valueLog2-fold change
3.8566 × 10-6-1.7
Fez1'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
8.5635 × 10-3-1.7
Fez1'hippocampus' vs 'cerebellum'organism partExpression data from adult Shh-responding astroglia cells in mice
Adjusted p-valueLog2-fold change
1.407 × 10-91.6
Fez1'Kit ligand' vs 'none' in 'wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
1.4944 × 10-8-1.6
Fez1'6 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
8.7582 × 10-8-1.6
Fez1'4 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.2658 × 10-7-1.6
Fez1'7 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
8.4805 × 10-6-1.6
Fez1'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
2.1277 × 10-4-1.6
Fez1'Mycobacterium tuberculosis; DBA/2J congenic; 70 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
2.2732 × 10-4-1.6
Fez1'bisphenol AF; 10 micromolar' vs 'vehicle'compoundTranscriptomic analyses of 11.5 dpc female germ cell (mouse) exposed or not to Bisphenol A analogues (BPAF and BADGE)
Adjusted p-valueLog2-fold change
4.0089 × 10-31.6
Fez1'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
3.0036 × 10-2-1.6
Fez1'Fhl1 knockdown by siRNA' vs 'wild type' at '1 day'phenotype, time3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1
Adjusted p-valueLog2-fold change
2.2922 × 10-231.5
Fez1'Abcc8 knockout' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of pancreatic beta cells from wild type and Abcc8 knockout mice
Adjusted p-valueLog2-fold change
1.8022 × 10-141.5
Fez1'8.5 millimolar; methoxyacetic acid' vs 'none' at '24 hour'compound, timeTranscription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid
Adjusted p-valueLog2-fold change
2.0386 × 10-7-1.5
Fez1'3 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
2.8825 × 10-6-1.5
Fez1'SARS coronavirus MA15; 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.736 × 10-51.5
Fez1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '30 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
1.2835 × 10-2-1.5
Fez1'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.4135 × 10-7-1.4
Fez1'mutant MyoD expression' at '12 hour' vs 'wild type MyoD expression' at '0 hour'phenotype, timeTranscription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation.
Adjusted p-valueLog2-fold change
3.044 × 10-6-1.4
Fez1'21 percent oxygen, 37 degree Celsius, no serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
6.3127 × 10-61.4
Fez1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '90 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
5.2499 × 10-51.4
Fez1'interleukin-3 and interleukin-33' vs 'interleukin-3'growth conditionStem cell factor programs the mast cell activation phenotype
Adjusted p-valueLog2-fold change
5.5993 × 10-51.4
Fez1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '60 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
1.9711 × 10-4-1.4
Fez1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.9387 × 10-41.4
Fez1'Crx knockout' vs 'control' at '6 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
4.1717 × 10-4-1.4
Fez1'glioblastoma multiforme' vs 'normal'diseaseAnalysis of the expression profiles of glioma-associated microglia/macrophages and naive control cells in Mus musculus.
Adjusted p-valueLog2-fold change
1.3021 × 10-3-1.4
Fez1'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
2.7711 × 10-3-1.4
Fez1'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
3.274 × 10-3-1.4
Fez1'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
4.6172 × 10-31.4
Fez1'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.2907 × 10-2-1.4
Fez1'T-cell depleted bone marrow transplant' vs 'none' in 'normal'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
2.5571 × 10-2-1.4
Fez1'PTEN null' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
7.4003 × 10-6-1.3
Fez1'Panct1' vs 'non-targeting siRNA'RNA interferenceA combined RNAi and localization approach for dissecting long noncoding RNAs reveals a function of Panct1 in ES cells
Adjusted p-valueLog2-fold change
5.1347 × 10-51.3
Fez1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '120 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
1.7736 × 10-4-1.3
Fez1'Mycobacterium tuberculosis; DBA/2J congenic; 30 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
1.915 × 10-4-1.3
Fez1'M-27; over-expressing IGF-IR' vs 'M-27; wild type'cell line, genotypeTranscription profiling of wild_type and IGF-I receptor over-expressing mouse lung carcinoma cells identifies a type I insulin like growth factor receptor regulated gene expression profile associated with an altered site-specificity of metastasis.
Adjusted p-valueLog2-fold change
1.3475 × 10-21.3
Fez1'synovial sarcoma' vs 'normal'diseaseTranscription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice
Adjusted p-valueLog2-fold change
1.8678 × 10-21.3
Fez1'ductus arteriosis' vs 'aorta'organism partGene Profiling in Mouse Fetal Ductus Arteriosus
Adjusted p-valueLog2-fold change
3.3272 × 10-21.3
Fez1'17beta-estradiol' vs 'DMSO' in 'wild type'compound, genotypeTranscription profiling of mouse male embryos treated with DMSO or 17beta-estradiol in wild type or ERalpha knock outs to assess the toxic effects of oestrogen exposure in fetal testis
Adjusted p-valueLog2-fold change
4.3776 × 10-311.2
Fez1'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
4.0446 × 10-91.2
Fez1'Abcc8-/-' vs 'wild type genotype' in 'normal; female'diet, genotype, sexEffects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
Adjusted p-valueLog2-fold change
4.2376 × 10-7-1.2
Fez1'10 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
2.4834 × 10-6-1.2
Fez1'carcinoma' vs 'normal'diseaseGene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse
Adjusted p-valueLog2-fold change
7.966 × 10-5-1.2
Fez1'Rfx2 knock out' vs 'wild type genotype'genotypeNext Generation Sequencing Analysis of Wild Type and Rfx2-/- Testicular Transcriptomes at post natal day 30 [RNA-Seq P30]
Adjusted p-valueLog2-fold change
8.2038 × 10-31.2
Fez1'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
9.8981 × 10-3-1.2
Fez1'overexpression of SRC-2' vs 'control'phenotypeA pivotal role of SRC-2 in Metastatic and Castration Resistant Prostate Cancer
Adjusted p-valueLog2-fold change
1.5085 × 10-21.2
Fez1'H9; undifferentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; undifferentiated embryonic stem cell' at '0 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
2.4024 × 10-21.2
Fez1'19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '5 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
2.9287 × 10-2-1.2
Fez1'damaged by neuropathy' vs 'control'sampling siteTranscriptional profiling of damaged and adjacent but intact dorsal root ganglia neurons against DRG cells from contralacteral control regions from mice with neuropathy
Adjusted p-valueLog2-fold change
5.0977 × 10-291.1
Fez1'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.9051 × 10-6-1.1
Fez1'2 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.2608 × 10-51.1
Fez1'PGC-1 beta knock in' vs 'wild type'genotypeTranscription profiling by array of skeletal muscle from PGC-1 beta transgenic mice
Adjusted p-valueLog2-fold change
9.3624 × 10-5-1.1
Fez1'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
9.4149 × 10-51.1
Fez1'Notch3 homozygous knockout' vs 'wild type genotype' in 'cerebellar microvascular fragments'genotype, organism partTranscription profiling by array of cerebral and cerebellar microvascular fragments from mice with Notch3 homozygous knockout vs samples from control, wild-type littermates
Adjusted p-valueLog2-fold change
7.855 × 10-4-1.1
Fez1'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 70 day' vs 'control; D2.B6-Chr7 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
2.6881 × 10-3-1.1
Fez1'21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
1.0731 × 10-2-1.1
Fez1'neuronal stem cell; positive staining for GFP and prominin' vs 'astrocyte; positive staining for GFP'cell type, phenotypeTranscription profiling by array of adult neural stem cells (hGFAP-GFP+/prominin1+ cells) compared to parenchymal astrocytes that are not neurogenic (hGFAP-GFP+ cells from the diencephalon)
Adjusted p-valueLog2-fold change
2.6422 × 10-21.1
Fez1'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
4.2018 × 10-2-1.1
Fez1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.9548 × 10-211
Fez1'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
3.5072 × 10-101
Fez1'Abcc8-/-' vs 'wild type genotype' in 'normal; male'diet, genotype, sexEffects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
Adjusted p-valueLog2-fold change
1.9765 × 10-71
Fez1'12 nanomolar; retinoic acid' vs 'none' at '24 hour'compound, timeTranscription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid
Adjusted p-valueLog2-fold change
5.4902 × 10-61
Fez1'Zbtb2 -/-' vs 'wild type genotype' in 'SerumLIF' at '2 day'genotype, growth condition, timeRNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.
Adjusted p-valueLog2-fold change
1.0679 × 10-5-1
Fez1'1 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
7.1553 × 10-5-1
Fez1'none; wasp knockout' vs 'none; wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
1.0781 × 10-41
Fez1'E2f1, E2f2, E2f3 triple knockout' vs 'control' at 'neonate'developmental stage, genotypeExpression data from lenses triply deficient for E2F1, E2F2, and E2F3 transcription factors
Adjusted p-valueLog2-fold change
8.3917 × 10-41
Fez1'Albumin Cre+/-;Hnf4a fl/fl' vs 'wild type genotype'genotypeTranscription profiling by array of liver-specific Hnf4alpha knock-out mice
Adjusted p-valueLog2-fold change
1.0742 × 10-31
Fez1'Notch3 homozygous knockout' vs 'wild type genotype' in 'cerebral microvascular fragments'genotype, organism partTranscription profiling by array of cerebral and cerebellar microvascular fragments from mice with Notch3 homozygous knockout vs samples from control, wild-type littermates
Adjusted p-valueLog2-fold change
1.3341 × 10-31
Fez1'calorie restricted diet' vs 'normal diet' at '15 month'age, dietTranscription profiling by array of cochleae from mice fed a calorie-restricted diet
Adjusted p-valueLog2-fold change
2.847 × 10-31
Fez1'tumor' vs 'normal' in 'liver'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
3.108 × 10-31
Fez1'12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
3.4399 × 10-3-1
Fez1'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week'age, genotypePrevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA
Adjusted p-valueLog2-fold change
7.5242 × 10-31
Fez1'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.3943 × 10-21
Fez1'1810027O10Rik knockout; gonad adipose tissue' vs 'wild type genotype; gonad adipose tissue'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
1.6123 × 10-21
Fez1'K14-Cre-ERT2 / CK1α fl/fl; 4-hydroxytamoxifen; none; 14 day' vs 'K14-Cre-ERT2; none; none'genotype, irradiate, timeAblation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin
Adjusted p-valueLog2-fold change
3.8085 × 10-2-1
Fez1'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
4.8222 × 10-21
Fez1'CD2314' vs 'none' at '11 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Synonym
UNC-76, UNC76
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
5473716, 10584259, ILMN_1213056, 4380693, A_52_P342828, 5014371, 5557194, 17516010, 5565769, 4990588, 4410576, 4527713, 4574630, 100876_at, R75432_rc_at, ILMN_2643495, 5590210, 4566679, 5587348, 4767290, 4653620, 5162921, 4949891, 5326735, 1454674_at, 4872295